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VTRARITLAATAVIIAGLDLGLKAWAGRALNDGSSTDLGLLHLRLAFNPGVAFSLGDTLPPAVLLAVTGV IVVALAVFAYRFTRTAALPVVLALAALLGGALANLIDRAADGLVTDYLHTGWFPTFNLADVFVVTGAAAL ALASWRASDTADTGAAT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2867 | - | - | 100% (157) | lipoprotein signal peptidase |
| M. gilvum PYR-GCK | Mflv_3640 | lspA | 8e-12 | 32.67% (150) | lipoprotein signal peptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1566 | lspA | 5e-12 | 33.79% (145) | lipoprotein signal peptidase |
| M. tuberculosis H37Rv | Rv1539 | lspA | 5e-12 | 33.79% (145) | lipoprotein signal peptidase |
| M. leprae Br4923 | MLBr_01199 | lspA | 5e-13 | 34.00% (150) | lipoprotein signal peptidase |
| M. abscessus ATCC 19977 | MAB_2700c | - | 1e-10 | 31.29% (163) | lipoprotein signal peptidase |
| M. marinum M | MMAR_2361 | lspA | 9e-12 | 33.33% (150) | lipoprotein signal peptidase LspA |
| M. avium 104 | MAV_3231 | lspA | 9e-12 | 33.33% (150) | lipoprotein signal peptidase |
| M. smegmatis MC2 155 | MSMEG_3174 | lspA | 4e-11 | 32.67% (150) | lipoprotein signal peptidase |
| M. thermoresistible (build 8) | TH_1296 | lspA | 9e-11 | 30.87% (149) | PROBABLE LIPOPROTEIN SIGNAL PEPTIDASE LSPA |
| M. ulcerans Agy99 | MUL_1537 | lspA | 6e-12 | 33.33% (150) | lipoprotein signal peptidase LspA |
| M. vanbaalenii PYR-1 | Mvan_2773 | lspA | 7e-12 | 31.87% (160) | lipoprotein signal peptidase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_1296|M.thermoresistible__bu --------------------------------------------------
Mvan_2773|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1566|M.bovis_AF2122/97 --------------------------------------------------
Rv1539|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2361|M.marinum_M --------------------------------------------------
MUL_1537|M.ulcerans_Agy99 MGDNHPIGPIGAVGAAPGDGVQGGADAIPVRRHQLRAVQRHQVDDFDIQI
MAV_3231|M.avium_104 --------------------------------------------------
MLBr_01199|M.leprae_Br4923 --------------------------------------------------
MSMEG_3174|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2700c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2867|M.gilvum_PYR-GCK --------------------------------------------------
TH_1296|M.thermoresistible__bu --------------------------------------------------
Mvan_2773|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1566|M.bovis_AF2122/97 --------------------------------------------------
Rv1539|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2361|M.marinum_M --------------------------------------------------
MUL_1537|M.ulcerans_Agy99 PAHGSGELRTVTRRSAHSVGARAGRDRSSGGDNGEAGHGGIISHPCHRHP
MAV_3231|M.avium_104 --------------------------------------------------
MLBr_01199|M.leprae_Br4923 --------------------------------------------------
MSMEG_3174|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2700c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2867|M.gilvum_PYR-GCK --------------------------------------------------
TH_1296|M.thermoresistible__bu --------------------------------------------------
Mvan_2773|M.vanbaalenii_PYR-1 -------------MTDESSSPVEPVTGEGKAAGDEPAQ----PSPPRRLR
Mb1566|M.bovis_AF2122/97 -------------MPDEPTGSADPLTSTEEAGGAGEPN---APAPPRRLR
Rv1539|M.tuberculosis_H37Rv -------------MPDEPTGSADPLTSTEEAGGAGEPN---APAPPRRLR
MMAR_2361|M.marinum_M -------------MSDEPTGSADPLTTAGETGVTEEPKVSAPEPPPRRLR
MUL_1537|M.ulcerans_Agy99 DVGTGTKLRDDGGVSDEPTGSADPLTTAGETGVTEEPKVSAPEPPPRRLR
MAV_3231|M.avium_104 -------------MPEEPTGSTAPQ-----------------DRPPRRLR
MLBr_01199|M.leprae_Br4923 ---------MMGRVPDGPTGLAALVPSVEEAQ---------AMLPPRRLR
MSMEG_3174|M.smegmatis_MC2_155 -------------MTDETSGPAEPVTDAPGDAES-------PAQPKRRLR
MAB_2700c|M.abscessus_ATCC_199 -------------MSDESET---------------------ARKPKRRIK
Mflv_2867|M.gilvum_PYR-GCK --------------------------------------------MTRARI
TH_1296|M.thermoresistible__bu -------VVLVLDIVTKVLAVRFLTPGQPVSIIGDTVTWTLVRNSGAAFS
Mvan_2773|M.vanbaalenii_PYR-1 LLLTVAGVVLVLDIVTKVLAVRLLTPGQPVSIIGDTVTWTLVRNSGAAFS
Mb1566|M.bovis_AF2122/97 MLLSVAVVVLTLDIVTKVVAVQLLPPGQPVSIIGDTVTWTLVRNSGAAFS
Rv1539|M.tuberculosis_H37Rv MLLSVAVVVLTLDIVTKVVAVQLLPPGQPVSIIGDTVTWTLVRNSGAAFS
MMAR_2361|M.marinum_M LLLSVAAVVLALDVVTKVLAVKLLPPGQPVSIIGDTVTWTLVRNSGAAFS
MUL_1537|M.ulcerans_Agy99 LLLSVAAVVLALDVVTKVLAVKLLPPGQPVSIIGDTVTWTLVRNSGAAFS
MAV_3231|M.avium_104 LLLSVAATVLALDIVTKVLAVKLLPPGQPVPIIGDTVTWTLVRNSGAAFS
MLBr_01199|M.leprae_Br4923 LLLSIAAVVLTLDIVTKVLAVKFLLPGKSVSIIGDTVTWTLVRNSGAAFS
MSMEG_3174|M.smegmatis_MC2_155 LLLTVAAVVLFLDVVTKVLAVRLLTPGQPVSIIGDTVTWTLVRNSGAAFS
MAB_2700c|M.abscessus_ATCC_199 LLLIVASVVLVLDVVTKVLAVRLLQPGKPVPIIGDTVTWTLVRNSGAAFS
Mflv_2867|M.gilvum_PYR-GCK TLAATAVIIAGLDLGLKAWAGRALNDGSSTDLG--LLHLRLAFNPGVAFS
: **: *. * : * *... : : *. *.*.***
TH_1296|M.thermoresistible__bu MATGYTWVLTLIATGVVIG----IIWMGRRLVSPWWAIGLGMILGGAMGN
Mvan_2773|M.vanbaalenii_PYR-1 MATGYTWVLTLVATGVVLG----IIWMGRRLVSPWWALGLGLILGGAMGN
Mb1566|M.bovis_AF2122/97 MATGYTWVLTLIATGVVVG----IFWMGRRLVSPWWALGLGMILGGAMGN
Rv1539|M.tuberculosis_H37Rv MATGYTWVLTLIATGVVVG----IFWMGRRLVSPWWALGLGMILGGAMGN
MMAR_2361|M.marinum_M MATGYTWVLTLIATGVVVG----IFWMGRRLVSPWWAVGLGMILGGAMGN
MUL_1537|M.ulcerans_Agy99 MATGYTWVLTLIATGVVVG----IFWMGRRLVSPWWAVGLGMILGGAMGN
MAV_3231|M.avium_104 MATGYTWVLTLIATGVVVG----IFWMGRRLVSPWWAVGLGMILGGAMGN
MLBr_01199|M.leprae_Br4923 MATGYTWVLTLIATGVVIG----IFWMGRRLVSSWWALGLGMILGGAMGN
MSMEG_3174|M.smegmatis_MC2_155 MATGYTWVLTLVATGVVIG----IIWMGRRLVSPWWALGLGLILGGATGN
MAB_2700c|M.abscessus_ATCC_199 FATGYTWVLTLIAISVVVG----ILFIGRRLVSTWWAIGLGMILGGALGN
Mflv_2867|M.gilvum_PYR-GCK LGDTLPPAVLLAVTGVIVVALAVFAYRFTRTAALPVVLALAALLGGALAN
:. . .: * . .*:: : : * .: .:.*. :**** .*
TH_1296|M.thermoresistible__bu LVDRFFRSPGPLRGHVVDFLSIGWWPVFNVADPSVVGGAILLVVLSLLGF
Mvan_2773|M.vanbaalenii_PYR-1 LVDRFFRSPGPLRGHVVDFLSIGWWPVFNVADPSVVGGAILLVVLSLFGF
Mb1566|M.bovis_AF2122/97 LVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVILSIFGF
Rv1539|M.tuberculosis_H37Rv LVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVILSIFGF
MMAR_2361|M.marinum_M LVDRFFRAPGPLRGHVVDFFSVGWWPVFNVADPSVVGGAILLVILSIFGF
MUL_1537|M.ulcerans_Agy99 LVDRFFRAPGPLRGHVVDFFSVGWWPVFNVADPSVVGGAILLVILSIFGF
MAV_3231|M.avium_104 LVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVVLSIFGY
MLBr_01199|M.leprae_Br4923 LVDRFFRAPAPLRGHVVDFLSIGWWPVFNVADPSVVVGAILLVVLSIFGF
MSMEG_3174|M.smegmatis_MC2_155 LVDRFFRSPGPLRGHVVDFFSVGWWPVFNVADPSVVGGAILLVALSLFGF
MAB_2700c|M.abscessus_ATCC_199 LVDRFFRGPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVALSLFGY
Mflv_2867|M.gilvum_PYR-GCK LIDR------AADGLVTDYLHTGWFPTFNLADVFVVTGAAALALASWRAS
*:** . * *.*:: **:*.**:** ** ** *. * .
TH_1296|M.thermoresistible__bu DYDTVGRRRN-SG---AAG-------------------------------
Mvan_2773|M.vanbaalenii_PYR-1 DFDSVGRRQP-DGGEDSVGRRQPDGGEDSVGRRQPDGGEDSVGRRRPDGG
Mb1566|M.bovis_AF2122/97 DFDTVGRRHA-DG--DTVGRRKADG-------------------------
Rv1539|M.tuberculosis_H37Rv DFDTVGRRHA-DG--DTVGRRKADG-------------------------
MMAR_2361|M.marinum_M DFDTVGRRK--AD--ER---------------------------------
MUL_1537|M.ulcerans_Agy99 DFDTVGRRK--AD--ER---------------------------------
MAV_3231|M.avium_104 DFDTVGRRKK-AD--QSRD-------------------------------
MLBr_01199|M.leprae_Br4923 DFDTVGRRKA-EF--DIAGQRKAEQR------------------------
MSMEG_3174|M.smegmatis_MC2_155 DFDTVGRRRPGEDAEPSAGASDSTPEAPAADGPDKPAGPVGPEDAAEESK
MAB_2700c|M.abscessus_ATCC_199 DYDREGRSTSKPASSGPEDSVNADPQASQTKPS-----------------
Mflv_2867|M.gilvum_PYR-GCK DTADTGAAT-----------------------------------------
* *
TH_1296|M.thermoresistible__bu -DAE-----
Mvan_2773|M.vanbaalenii_PYR-1 EDSENG---
Mb1566|M.bovis_AF2122/97 ---------
Rv1539|M.tuberculosis_H37Rv ---------
MMAR_2361|M.marinum_M ---------
MUL_1537|M.ulcerans_Agy99 ---------
MAV_3231|M.avium_104 ---------
MLBr_01199|M.leprae_Br4923 ---------
MSMEG_3174|M.smegmatis_MC2_155 TVGHQAEPS
MAB_2700c|M.abscessus_ATCC_199 ---------
Mflv_2867|M.gilvum_PYR-GCK ---------