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PDTDRLIISRRTLLRASLAGALLVPAAACGTPSSAPSSTGLIANRPRLTHGVATGDPRPDGALVWARADE PARMIVETAATESFSNPNRIEGPQLTPESDGTGRVRITGLEPGQTVHYRVTLEGEDGATSEPVTGVFKTV PTQAQDITFVWGGDVVGQGWGINKQGGMSIFGAMADRNPDFFIHSGDAIYADGPVPETQKRNDGGMYVNL TDPAKDHVAQTLADYRGNYAYNLTDQHYRRFNATVPQLIQWDDHEVINNWFPHESLVGQGRAGYTETDVD KLAGYAYQAWREWQPVDPSEAVDGRLYRKVSYGPLLDVFVLDMRTYKNPNPQAWATSDDDGILGREQTQW LINGLKNSTAAWKIVANDLPISIVVPDKATNPEQGPASMEAVAQGDNGRPLGREIAFSRILSATKDVRNI VYLTADVHYTAAISYHPDRAAFGDFTPFWEFVSGPLNAGAFPQSPLDGTFGPRYEFVHAPEVENTSPAEG FQHFGEVHIDSDTRVLTVNLRDATGKSLYSTDLAPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5508 | - | - | 100% (527) | alkaline phosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2747 | - | 2e-08 | 24.77% (214) | hypothetical protein Mflv_2747 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3749 | - | 1e-169 | 58.69% (518) | putative phosphodiesterase/alkaline phosphatase |
| M. marinum M | MMAR_2145 | - | 1e-05 | 26.55% (177) | hypothetical protein MMAR_2145 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4164 | - | 7e-08 | 26.22% (225) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1026 | - | 2e-31 | 27.81% (453) | alkaline phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2747|M.gilvum_PYR-GCK -------------MSVTLVLGPVLRHVGESTA--------AVWVQTDAPA
TH_4164|M.thermoresistible__bu ---------------MGLLLGPVLRHVSETTA--------QVWVQTDRPA
MMAR_2145|M.marinum_M --------------MAELVLGPLLRHVGECDA--------TVWVETSKPC
MSMEG_5508|M.smegmatis_MC2_155 MPDTDRLIISRRTLLRASLAGALLVPAAACGTPSSAPSSTGLIANRPRLT
MAB_3749|M.abscessus_ATCC_1997 -----MTAFPRRTVLRAALLGLAAVPVAACGP--------ALVTTRPRLT
Mvan_1026|M.vanbaalenii_PYR-1 ----MSPKLSRRAALKGAVGLAAVPLLGFTGEPR------RGVVAADPFT
: . .
Mflv_2747|M.gilvum_PYR-GCK EVEVLG--CSARTFQVQEHH--------------YALVPITGLTPDSVHE
TH_4164|M.thermoresistible__bu TVSVLG--CSASTFQVQDYH--------------YALVPVTGLTPGTTTR
MMAR_2145|M.marinum_M EVEILG--HRERAWTVAGHH--------------YALVVVRGLQADSSTP
MSMEG_5508|M.smegmatis_MC2_155 HGVATGDPRPDGALVWARAD--------------EPARMIVETAATESFS
MAB_3749|M.abscessus_ATCC_1997 HGVASGFPRTDGAVIWARSD--------------RPAALIVETAATESFS
Mvan_1026|M.vanbaalenii_PYR-1 LGVASGEPSPDGVVIWTRLAPRPLADDGLGGMPARVVDVEWEVAGDETFT
* .
Mflv_2747|M.gilvum_PYR-GCK YQVRIDGEIVWPEPDS-----------EFPPSVIRTRGPAGAHRLKVVFG
TH_4164|M.thermoresistible__bu YEVHVDGERVWPLPDSS-FPPDSSPPVSFPPSVIRTRGPESAHRARAVFG
MMAR_2145|M.marinum_M YEVHLDGNRVWPLPDA------------VRLSTIRTLN--NRDSLDLVFG
MSMEG_5508|M.smegmatis_MC2_155 NPNRIEGPQLTPESDGTGRVRITGLEPGQTVHYRVTLEGEDGATSEPVTG
MAB_3749|M.abscessus_ATCC_1997 DTRRFTGPLLTPDADGTGRIRLTGLPADSEVHYRVTLD-ADGALSEPATG
Mvan_1026|M.vanbaalenii_PYR-1 RIEQRGRSVATPESAHSVHVEVAGLRPGGEYFYRFRAEGYLSPAGRTRTA
: * . .
Mflv_2747|M.gilvum_PYR-GCK SCRYPKTGVQKLDDKLGLDALDC--------YAERLTATPVDEWPDALLL
TH_4164|M.thermoresistible__bu SCRYPKTGVDDVDDKLGHDALDR--------YAARMAQQPVDDWPDMLVL
MMAR_2145|M.marinum_M SCRFATLTATAGNTHFNADALDA--------LAWRMYEQPPDRWPDALLL
MSMEG_5508|M.smegmatis_MC2_155 VFKTVPTQAQDITFVWGGDVVGQGWGIN-KQGGMSIFGAMADRNPDFFIH
MAB_3749|M.abscessus_ATCC_1997 VFRTAPATARDVRLIWSGDVAGQGFGINPDIGGMTVFRTMAERNPHFFIH
Mvan_1026|M.vanbaalenii_PYR-1 PATDAPASSLTMCFASCSNFEQG---------WFTAYRRLAEEEPDLVLH
: : *. .:
Mflv_2747|M.gilvum_PYR-GCK LGDQVYADELTPEARRNLSGRRQTK----RRPPDEVVTFDEYEGLYRHTW
TH_4164|M.thermoresistible__bu LGDQVYADELTPEARRQLTGRRRRKQTRTKRPPDEVVSFTEYERLYRHSW
MMAR_2145|M.marinum_M LGDQIYADDLSPETLRCVIDRRGID----DPHSAEVRDFEEYTWLYAESW
MSMEG_5508|M.smegmatis_MC2_155 SGDAIYADGPVPETQKRNDGGMYVN-LTDPAKDHVAQTLADYRGNYAYNL
MAB_3749|M.abscessus_ATCC_1997 SGDTVYADVPIPETLPLPDGRIWRN-EISEAKSAVAQTLDQYRGQHAYNL
Mvan_1026|M.vanbaalenii_PYR-1 LGDYQYEYAAREHAVRRHVG-------------PETVTLANYRQRYAQYK
** * .: . . : :* :
Mflv_2747|M.gilvum_PYR-GCK GDPEIRWILSTLPTAMIFDDHDIRDDWNTSAPWRAEVNEKPWWRDRIHAG
TH_4164|M.thermoresistible__bu TDPEIRWIMSTVPTAMIFDDHDIRDDWNTSGRWREEMSAQPWWRERIRAG
MMAR_2145|M.marinum_M SDPQVRWLLSTVPTSMIFDDHDVHDDWNTSQSWRQEIQATPWWKERIVSA
MSMEG_5508|M.smegmatis_MC2_155 TDQHYRRFNATVPQLIQWDDHEVINNWFPHESLVGQGRAGYTETDVDKLA
MAB_3749|M.abscessus_ATCC_1997 TDANYRYFNAHVPQLVQWDDHEVINNWYPGEVLDNDK---YTEKRVDILA
Mvan_1026|M.vanbaalenii_PYR-1 TDPDLQAAHAAAPWLVVWDDHELDNNWADEVPEEPQPD----YSARRAAA
* . : : * : :***:: ::* : .
Mflv_2747|M.gilvum_PYR-GCK LGSYWVYQHIGNLSPEELASDEDYQKVLANDGDCWPHLVELADRADYEVD
TH_4164|M.thermoresistible__bu LASYWVYQHIGNLSPEQLEEDPDYQRIRGIDGDAWPALVELADRADAEVD
MMAR_2145|M.marinum_M LSSYWVYQHLGNLTPAALAEDELYQRVRAHPGDAAPLIRQFATAADEEAD
MSMEG_5508|M.smegmatis_MC2_155 GYAYQAWREWQPVDPSEAVDGRLYRKVSYG-----PLLDVFVLDMRTYKN
MAB_3749|M.abscessus_ATCC_1997 RHGHRAFHEWQPLEAREAVDGRVYQRVSYG-----PLLDVFLLDMRSYKD
Mvan_1026|M.vanbaalenii_PYR-1 LQAYYENMPLRSSAMPRGGEMRLFRRVEWGALATFHMLDTRQYRSDQACD
.: . :::: : :
Mflv_2747|M.gilvum_PYR-GCK GDKGLRFSFRWDLGRSRLIMVDSRNARILDSGERKMLGDREFRWLEDQVN
TH_4164|M.thermoresistible__bu ANKGVRFSYRWDLGCTRFIMMDSRNGRILDSGERMMLGEKEFRWVEEQAA
MMAR_2145|M.marinum_M GGKGAQWSYRRDLGNTRLLVIDTRCGRILSAGRRSMLSENEFSWIEQQTG
MSMEG_5508|M.smegmatis_MC2_155 PNPQAWA----------------------TSDDDGILGREQTQWLINGLK
MAB_3749|M.abscessus_ATCC_1997 PNSPNRQ----------------------QHG--TILGARQAGWLINEMA
Mvan_1026|M.vanbaalenii_PYR-1 DQYRSDCPAR-------------------LDPFRTLTGQAQEQWLLNGFQ
: . : *: :
Mflv_2747|M.gilvum_PYR-GCK DDLGTVDHLLIGSSLPWLLPPALGDVQTINEIAAD--RDGLRGKLAETIR
TH_4164|M.thermoresistible__bu DGIENVEHLVLGSSVPWLMPPALADLQAVNELAAD--RPGWRGALAEKIR
MMAR_2145|M.marinum_M ---GDYDHLLVGSSLPWLLPRTLHDLESWDEHLASGARGRLLAGWAEKLR
MSMEG_5508|M.smegmatis_MC2_155 NSTAAWKIVANDLPISIVVP----DKATNPEQGPASMEAVAQGDNGRPLG
MAB_3749|M.abscessus_ATCC_1997 SSTAVWKVVANDLPLALVVP----DGTTD-------FEAVANGDNDLPLG
Mvan_1026|M.vanbaalenii_PYR-1 QSRARWDLLGQQVFFSQLDLTPGPGRGFN--------PDAWDGYVANRDR
. : .. : . .
Mflv_2747|M.gilvum_PYR-GCK QTADLEHWPAFLKSFLRLSALIE--SAADHSSTGPATVSVLSGDVHHSYA
TH_4164|M.thermoresistible__bu QGADLEHWPAFMKSFLRLTTMIR--AAADHP-DGPATVTVLSGDVHHSYA
MMAR_2145|M.marinum_M RAADLEHWAAFGESFDRLTRLFSRVSRGQVSGPAPATICVLSGDVHHAYV
MSMEG_5508|M.smegmatis_MC2_155 REIAFSRILSATKD--------------------VRNIVYLTADVH--YT
MAB_3749|M.abscessus_ATCC_1997 RETELAHILSQLKARK------------------VRNVVWLTADVH--YT
Mvan_1026|M.vanbaalenii_PYR-1 ITTGIANSP-------------------------VRNAVLLTGDVHAHWA
: . . *:.*** :.
Mflv_2747|M.gilvum_PYR-GCK ARADFP--GKHATRVHQLVCSPVHNYVPAPLKPFFRLVWSPRLARVTRRW
TH_4164|M.thermoresistible__bu ARADFDGLGADAAAVHQLVCSPVHNYVPAFVKPVFALGWSRRLAPLTRRW
MMAR_2145|M.marinum_M AQARFS--EPVHSRVYQLTCSPLHNYVPAAMKMAFRISWSRVTERATRFL
MSMEG_5508|M.smegmatis_MC2_155 AAISYH-----PDRAAFGDFTPFWEFVSGPLN-----AGAFPQSPLDGTF
MAB_3749|M.abscessus_ATCC_1997 AAHEYS-----PARAAFTDFDPFWEFVSGPLN-----AGAGKESTLDGTF
Mvan_1026|M.vanbaalenii_PYR-1 AEVYERAGDPLSRRVATELVTTSISSGGDGSDTRADVDEILPDNPHIRYF
* . . . .
Mflv_2747|M.gilvum_PYR-GCK ARRAG-SPDLPMSWRNLSGPLFGNTIASLNVSGRDAEVVFEQP--RDDGS
TH_4164|M.thermoresistible__bu ARRHG-VPALPLTWTNTCGPIFGNTIATLRVDGPQAEVVFEQP--DDAGD
MMAR_2145|M.marinum_M LNRVSTVPPPPIDWDPIAGPFFGDQVATLRVRGRTIGVVLEQAGTDDTGH
MSMEG_5508|M.smegmatis_MC2_155 GPRYEFVHAPEVENTSPAEGFQHFGEVHIDSDTRVLTVNLRDATGKSLYS
MAB_3749|M.abscessus_ATCC_1997 GPRADFVHAAPPGKQSPLDGYQHFGQIDIDGGSGDLTVTLCDAAGAALYT
Mvan_1026|M.vanbaalenii_PYR-1 SNRRGYVRTR-ITPDELRADFRTVPYVTSPGAPVQVGASFRIPDRLPQLL
* . : .
Mflv_2747|M.gilvum_PYR-GCK --LTSVITVSLTD------------
TH_4164|M.thermoresistible__bu --LGRVARVGLTGSAASPPISPAAR
MMAR_2145|M.marinum_M PRLRMVADIALA-------------
MSMEG_5508|M.smegmatis_MC2_155 TDLAPA-------------------
MAB_3749|M.abscessus_ATCC_1997 RTLARI-------------------
Mvan_1026|M.vanbaalenii_PYR-1 -------------------------