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MTFSLQESIISVTMSDDHAETTKWDPGFTRQITDWVGPVIRRYFRAEVRGMDSMPATGGALVVSNHSGGM LTPDVMVFAPSFYERFGFDRPLYTLAHYGVFMGPLGDLLRRAGVIEASRENAADALRSGAVVLVFPGGDY DSYRPTMTANKVDFAGRTGYVRTALETGVPIVPVVSIGAQETQMFLARGDSIARRIGLTRARMEILPISI GFPFGLSVIFPPNLPLPSKIVTQVLEPVDITAQFGEDPDIDEVDQYVRSTMQKALDELARTRRFPVLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2426 | - | - | 100% (278) | phospholipid/glycerol acyltransferase |
| M. gilvum PYR-GCK | Mflv_0434 | - | 2e-89 | 58.78% (262) | phospholipid/glycerol acyltransferase |
| M. gilvum PYR-GCK | Mflv_1020 | - | 1e-56 | 45.66% (265) | phospholipid/glycerol acyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1463c | - | 2e-92 | 62.65% (257) | hypothetical protein Mb1463c |
| M. tuberculosis H37Rv | Rv1428c | - | 2e-92 | 62.65% (257) | hypothetical protein Rv1428c |
| M. leprae Br4923 | MLBr_02427 | - | 7e-21 | 31.92% (260) | hypothetical protein MLBr_02427 |
| M. abscessus ATCC 19977 | MAB_4002c | - | 3e-25 | 35.68% (241) | putative acyltransferase |
| M. marinum M | MMAR_5273 | - | 1e-97 | 64.50% (262) | hypothetical protein MMAR_5273 |
| M. avium 104 | MAV_3346 | - | 2e-94 | 61.48% (270) | acyltransferase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0305 | - | 6e-96 | 62.12% (264) | acyltransferase domain-containing protein |
| M. thermoresistible (build 8) | TH_1905 | - | 3e-90 | 60.92% (261) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4347 | - | 3e-98 | 64.89% (262) | hypothetical protein MUL_4347 |
| M. vanbaalenii PYR-1 | Mvan_4226 | - | 1e-139 | 86.33% (278) | phospholipid/glycerol acyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1463c|M.bovis_AF2122/97 --------------------------------------------------
Rv1428c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3346|M.avium_104 --------------------------------------------------
MSMEG_0305|M.smegmatis_MC2_155 --------------------------------------------------
TH_1905|M.thermoresistible__bu --------------------------------------------------
Mflv_2426|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4226|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_5273|M.marinum_M --------------------------------------------------
MUL_4347|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02427|M.leprae_Br4923 MNSVGWGQVDTVVGETRANVIPLHIKRGRVASR-RRAGYRVDGSRQHPSL
MAB_4002c|M.abscessus_ATCC_199 -----------MAGETKAKVIQLQANSERHAARARRAEARADAGRRHPSS
Mb1463c|M.bovis_AF2122/97 -------------------------------------------------M
Rv1428c|M.tuberculosis_H37Rv -------------------------------------------------M
MAV_3346|M.avium_104 --------------------------------------------------
MSMEG_0305|M.smegmatis_MC2_155 -------------------------------------------------M
TH_1905|M.thermoresistible__bu -------------------------------------------------L
Mflv_2426|M.gilvum_PYR-GCK ---------------------------------------------MTFSL
Mvan_4226|M.vanbaalenii_PYR-1 ---------------------------------------------MTFSF
MMAR_5273|M.marinum_M -------------------------------------------------M
MUL_4347|M.ulcerans_Agy99 -------------------------------------------------M
MLBr_02427|M.leprae_Br4923 LSDLRGRASAEQIAAVVREIDEHRRSTGATNLWEVTTEAPLSELAQHVAA
MAB_4002c|M.abscessus_ATCC_199 LTNGAPVHDPAETAAVIHDLNEIRAAQGNA---HVGDEESLTALAANIAA
Mb1463c|M.bovis_AF2122/97 SETDSPGNGDDAGIGDIGKFDPGLTQRLIS-VLRPVLKTYHRSQVHGLDS
Rv1428c|M.tuberculosis_H37Rv SETDSPGNGDDAGIGDIGKFDPGLTQRLIS-VLRPVLKTYHRSQVHGLDS
MAV_3346|M.avium_104 -MTDS----DNADGGDIGKFDPVLTQRLMT-VMRPVLKAYFRSEVHGLES
MSMEG_0305|M.smegmatis_MC2_155 AATDT-------DPGEITKWDPGLTEKVMG-WLRPLIKGYHRAEVHGLDT
TH_1905|M.thermoresistible__bu SPTDI-------EPSEIAKWDPDLTERVMG-LLRPLIKGYHRAEIRGLDT
Mflv_2426|M.gilvum_PYR-GCK QESIISVT-MSDDHAETTKWDPGFTRQITD-WVGPVIRRYFRAEVRGMDS
Mvan_4226|M.vanbaalenii_PYR-1 PESSISGT-MSDELAETAKWDPGFTRRITG-WVGPVIRRYFRAEVRDIES
MMAR_5273|M.marinum_M NRNEIDG-------PEIAKWDRGFTSTVIG-AVTPVIKRWFRSEVRGLES
MUL_4347|M.ulcerans_Agy99 NRNEIDG-------PEIAKWDRGFTSTVIG-AVTPVIKRWFRSEVRGLES
MLBr_02427|M.leprae_Br4923 VAGFLRQRLTGDYTVDEFGFDPHFNNAIIRPFLRFFFKSWFRVEVSGIEN
MAB_4002c|M.abscessus_ATCC_199 VAEFIRRRVGGDYSVDDFGFDEHLNESLLLPLLRPLFNRWFRVDVTGVEN
: :* :. : : .:. :.* :: .::.
Mb1463c|M.bovis_AF2122/97 FPP-GGALVVANHSGGMFPMDVPVFSVDFYDKFGYDRPVYTLSHDILFMG
Rv1428c|M.tuberculosis_H37Rv FPP-GGALVVANHSGGMFPMDVPVFSVDFYDKFGYDRPVYTLSHDILFMG
MAV_3346|M.avium_104 FPP-GGALVVGNHSGGMFPMDVPIFSVHFYDKYGYDRPIYTLSHDILMTG
MSMEG_0305|M.smegmatis_MC2_155 FPN-GGALVVSNHSGGLFPMDVPVFATGFYEKFGYDRPVYTLSHDMLMTG
TH_1905|M.thermoresistible__bu FPH-GGALVVSNHSGGLFPMDVPVFATGFYERFGYDRPVYTLSHDILLTG
Mflv_2426|M.gilvum_PYR-GCK MPATGGALVVSNHSGGMLTPDVMVFAPSFYERFGFDRPLYTLAHYGVFMG
Mvan_4226|M.vanbaalenii_PYR-1 VPAEGGVLIVSNHSGGMLTPDVMVFAPAFYEHFGYDRPLYTLAHYGVLIG
MMAR_5273|M.marinum_M FPPTGGVLVVSNHSGGVLTPDWNVLAPALYGKFGYQRPLYTLAHYGVFIT
MUL_4347|M.ulcerans_Agy99 FPPTGGVLVVSNHSGGVLTPDWNVLAPALYGKFGYQRPLYTLAHYGVFIT
MLBr_02427|M.leprae_Br4923 LPSTGGALVVANHAG-VLPFDGLMLSLAVHDEHPAQRDLRLLVADMVFDL
MAB_4002c|M.abscessus_ATCC_199 IPATGGALVVANHAG-VLPLDGLMLSVAVHDRCPGNRTLRNLAADMVFDA
.* **.*:*.**:* ::. * ::: .: . :* : * ::
Mb1463c|M.bovis_AF2122/97 LTG-DLFRRTGYIRATRENAAKALRSGGVVVVFPGGDYDAYRPTFAENVI
Rv1428c|M.tuberculosis_H37Rv LTG-DLFRRTGYIRATRENAAKALRSGGVVVVFPGGDYDAYRPTFAENVI
MAV_3346|M.avium_104 PTG-DFFRRTGYIRANRENAAAALRSGGVVIVFPGGDYDAYRPTLAENVI
MSMEG_0305|M.smegmatis_MC2_155 PTA-DFFKKTGFIRANHENADEALRSGGVVVVFPGGDYDVYRPTLAANKI
TH_1905|M.thermoresistible__bu PTA-DFFIRTGFIRANHDNADEALRSGGVVIVFPGGDYDVYRPTFAQHKI
Mflv_2426|M.gilvum_PYR-GCK PLG-DLLRRAGVIEASRENAADALRSGAVVLVFPGGDYDSYRPTMTANKV
Mvan_4226|M.vanbaalenii_PYR-1 PLG-DLLRRAGVIEASRDNAAEALRSGAVVLVFPGGDYDSYRPTMAANVV
MMAR_5273|M.marinum_M PFR-ASLGRLGVIHASPDNATAALRSGGVVLVFPGGDYDAFRPTLAQNVI
MUL_4347|M.ulcerans_Agy99 PFR-ASLGRLGVIHASPDNATAALRSGGVVLVFPGGDYDAFRPTLAQNVI
MLBr_02427|M.leprae_Br4923 PVVGEAVRKAGHTVACTSDAHRLLAAGELTAVFPEGYKGLGKRFQDRYRL
MAB_4002c|M.abscessus_ATCC_199 PFLGQLARKAGHTLACTADAHRLLSGGELTAVFPEGYKGLGKPFKDRYKL
: * * :* * .* :. *** * . : :
Mb1463c|M.bovis_AF2122/97 DFNGRKGYVSTAVEAGVPIVPAVSIGGQESQLYLSRGTWLARRLG-LKRL
Rv1428c|M.tuberculosis_H37Rv DFNGRKGYVSTAVEAGVPIVPAVSIGGQESQLYLSRGTWLARRLG-LKRL
MAV_3346|M.avium_104 DFDGRKGYVRTAIEAGVPIVPAVSIGGQETQLYLTRGTWLAERLG-IKRL
MSMEG_0305|M.smegmatis_MC2_155 DFAGRTGYVRAALNAGVPIVPMVGVGGQETQLFLSRGTAVAKALGPIARL
TH_1905|M.thermoresistible__bu DFDGRTGYVRAALNAGVPIVPTVAVGGQESQLFLSRGESLARLLR-LDKL
Mflv_2426|M.gilvum_PYR-GCK DFAGRTGYVRTALETGVPIVPVVSIGAQETQMFLARGDSIARRIG--LTR
Mvan_4226|M.vanbaalenii_PYR-1 DFAGRTGYVRAALESGVPIVPVVSIGAQETQMFLARGDAIARRIG--LTR
MMAR_5273|M.marinum_M DFGGRTGYVRAAMRAGAPIVPAVSIGGQETQLFVSRGNWLAKRLG--LKR
MUL_4347|M.ulcerans_Agy99 DFGGRTGYVRAAMRAGVPIVPAVSIGGQETQLFVSRGNWLAKRLG--LKR
MLBr_02427|M.leprae_Br4923 QRFGRGGFVKAALSTKATIVPCSIVGSEEIYPMLTDVKLLARLFG-----
MAB_4002c|M.abscessus_ATCC_199 QRFGRGGFVAAAIRTGAPIVPCSIVGSEEIYPMIADLKVIARLFG-----
: ** *:* :*: : ..*** :*.:* :: :*. :
Mb1463c|M.bovis_AF2122/97 LRSDILPISFGFPFGFSAAIPPNLPLPAKIVMQVLDPINLTKQFGEDPD-
Rv1428c|M.tuberculosis_H37Rv LRSDILPISFGFPFGFSAAIPPNLPLPAKIVMQVLDPINLTKQFGEDPD-
MAV_3346|M.avium_104 LRSAILPVSFGFPFGLSAVIPPNLPLPAKIVTRVLDPIDIAKQFGEDPD-
MSMEG_0305|M.smegmatis_MC2_155 ARTKIVPVSFGFPFGLSAVLPLNVPLPSKIVMKTLPPIDITAEFGEDPD-
TH_1905|M.thermoresistible__bu MRVKILPISFGFPWGLSAVVPVNVPLPTKIVMQVLPPIDIEAEFGPDPD-
Mflv_2426|M.gilvum_PYR-GCK ARMEILPISIGFPFGLSVIFPPNLPLPSKIVTQVLEPVDITAQFGEDPD-
Mvan_4226|M.vanbaalenii_PYR-1 ARMEILPVSIGFPFGLSVLVPPNLPLPSKIVTQVLEPIDITAQFGQDPD-
MMAR_5273|M.marinum_M IRIEILPITIGLPFGLTMFFPANFPLPAKIVYQVLEPIDIAAQFGTDPD-
MUL_4347|M.ulcerans_Agy99 IRIEILPITIGLPFGLTMFFPANFPLPAKIVYQVLEPIDIAAQFGTDPD-
MLBr_02427|M.leprae_Br4923 --VPYFPVTPLFPLAGPAGLVP---LPSKWRIAFGEPIYTTDYAATDADD
MAB_4002c|M.abscessus_ATCC_199 --LPYFPVTPLFPAAGPVGLVP---LPSKWHIEFGTPIPTDGYDEAAADD
.*:: :* . . . **:* *: .*
Mb1463c|M.bovis_AF2122/97 ---VDAVDEHVRSVMQQALNDLAAKRRFPILG
Rv1428c|M.tuberculosis_H37Rv ---VDAVDEHVRSVMQQALNDLAAKRRFPILG
MAV_3346|M.avium_104 ---VDEVDEYVRSVMQQALNELAAERRFPILG
MSMEG_0305|M.smegmatis_MC2_155 ---IDEVDAHVRHVMQQALDELAEQRRFPVIG
TH_1905|M.thermoresistible__bu ---IDEVDAHVRRTMQRALDELAAERRLPVLG
Mflv_2426|M.gilvum_PYR-GCK ---IDEVDQYVRSTMQKALDELARTRRFPVLG
Mvan_4226|M.vanbaalenii_PYR-1 ---IDEVDYHVRSVMQAALDELARNRRFPVLG
MMAR_5273|M.marinum_M ---VAQVDAHVRSVMQSALDRLGEQRRFPVLG
MUL_4347|M.ulcerans_Agy99 ---VAQVDAHVRSVMQSALDRLGEQRRFPVLG
MLBr_02427|M.leprae_Br4923 PMVTFELTDQVRETIQQTLYRLLAGRRNIFFG
MAB_4002c|M.abscessus_ATCC_199 PMVTFEVTDQVRETIQQTLYRLLAGRRNMFFG
: ** .:* :* * ** .:*