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VPNGANFVDLHVYVGGAAELDGPGTLYSYVYGEQTPDFPLPFTYPPFAAVVFYPLHVLPFGLVAFAWQIG IIAALYGVVRLSQRLLGGGDRRVAMLWTAVGIWTEPLRSTFDYGQVNVLLVLAILYAVYSTRWWLSGLLV GLAAGIKLTPAVAGLYFVGARRWAAVVCSAAVFLLTIGVSALIVGEQTRFYFTELLGDADRVGPVGTSFN QSWRGGISRILGHDAGYGPVVLIGVAVTAVLALLAWRAIDGAQDRLGGIVVVQLFGLLLSPISWTHHWVW LIPLMIWLLHGPLRDRLGAKVLGWGWLALILVGVPWLLSFAQPTIWVIPRPWYLAWAGLIYIVATVATLA WIAIRGSRRCRGPSPDPSV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2153 | pimE | - | 100% (369) | mannosyltransferase |
| M. gilvum PYR-GCK | Mflv_0993 | - | 1e-40 | 34.49% (374) | hypothetical protein Mflv_0993 |
| M. gilvum PYR-GCK | Mflv_2968 | - | 3e-35 | 31.79% (368) | putative integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1190 | pimE | 1e-160 | 72.68% (355) | mannosyltransferase |
| M. tuberculosis H37Rv | Rv1159 | pimE | 1e-160 | 72.68% (355) | mannosyltransferase |
| M. leprae Br4923 | MLBr_01504 | pimE | 1e-159 | 72.63% (358) | mannosyltransferase |
| M. abscessus ATCC 19977 | MAB_1304 | pimE | 1e-147 | 67.23% (357) | mannosyltransferase |
| M. marinum M | MMAR_4292 | pimE | 1e-168 | 76.60% (359) | transmembrane protein |
| M. avium 104 | MAV_1298 | pimE | 1e-168 | 73.87% (375) | mannosyltransferase |
| M. smegmatis MC2 155 | MSMEG_5149 | pimE | 0.0 | 83.90% (354) | mannosyltransferase |
| M. thermoresistible (build 8) | TH_0647 | - | 1e-178 | 76.46% (378) | CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1006 | pimE | 1e-166 | 75.49% (359) | mannosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4550 | pimE | 0.0 | 87.84% (370) | mannosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1190|M.bovis_AF2122/97 MCRTLIDGPVRSAIAKVRQIDTTSSTPAAAR---RVTSPPARETRAAVLL
Rv1159|M.tuberculosis_H37Rv MCRTLIDGPVRSAIAKVRQIDTTSSTPAAAR---RVTSPPARETRAAVLL
MMAR_4292|M.marinum_M MTGHLGN----WVGTRVGRIDTTSAAPAASTTRHKAVSPKVWGRRGAPLL
MUL_1006|M.ulcerans_Agy99 MTGHLGN----WVGTRVGRIDTTSAAPAASTTRHKAVSPKVWGRRGAPLL
MLBr_01504|M.leprae_Br4923 MVAVIMAK-AFAAVARVGQIDTTTTNTTAAASAPRVRRLTSRLNAAAPLL
MAV_1298|M.avium_104 --------------------------------------------MAAPLL
Mflv_2153|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4550|M.vanbaalenii_PYR-1 ------------------------------MPARRAARLVAHLSAAAPAL
MSMEG_5149|M.smegmatis_MC2_155 ------------------------------------------------ML
TH_0647|M.thermoresistible__bu --------------------------------VSTTVRRSNRLLIAAPVL
MAB_1304|M.abscessus_ATCC_1997 ---------------MATEKTEPTRANVEPPMPTRGASAWRRVRAWGPWL
Mb1190|M.bovis_AF2122/97 LVLSVGARLAWTYLAPNGANFVDLHVYVSGAASLDHPGTLYGYVYADQTP
Rv1159|M.tuberculosis_H37Rv LVLSVGARLAWTYLAPNGANFVDLHVYVSGAASLDHPGTLYGYVYADQTP
MMAR_4292|M.marinum_M LVFSVAARLAWTYLTSNGANFVDLHVYVGGAAALDHPGSLYSYVYADQTP
MUL_1006|M.ulcerans_Agy99 LVFSVAARLAWTYLTSNGANFVDLHVYVGGAAALGHPGSLYSYVYADQTP
MLBr_01504|M.leprae_Br4923 LVFSVAVRLAWTYLAPNGANFVDLHVYLGGAATIDHPGTLYRYVYVDQTP
MAV_1298|M.avium_104 LVASVAARLAWTYLVPNGANFVDLHVYLGGAAALDHPGTLYSYVYADQTP
Mflv_2153|M.gilvum_PYR-GCK --------------MPNGANFVDLHVYVGGAAELDGPGTLYSYVYGEQTP
Mvan_4550|M.vanbaalenii_PYR-1 LILSIAARLAWTYLVPNGANFVDLHVYVGGAAELDGPGTLYEYVYADQTP
MSMEG_5149|M.smegmatis_MC2_155 LVVSILARLAWTYLVPNGANFVDLHVYVGGADALDGPGALYDYVYADQTP
TH_0647|M.thermoresistible__bu LVVSIAARLAWAYLLPNGANFVDLHVYVGGAERVDGPGALYDYVYADQTP
MAB_1304|M.abscessus_ATCC_1997 LGLSVAVRLAWAYLTPHGADLVDLHVYVSGPATLGH-GNLYEFTYPDKTP
.:**::******:.*. :. * ** :.* ::**
Mb1190|M.bovis_AF2122/97 DFPLPFTYPPFAAVVFYPLHLVPFGLIALLWQVVTMAALYGAVRISQRLM
Rv1159|M.tuberculosis_H37Rv DFPLPFTYPPFAAVVFYPLHLVPFGLIALLWQVVTMAALYGAVRISQRLM
MMAR_4292|M.marinum_M DFPLPFTYPPFAAVVFYPLHLLPFGLVAFLWQLATIAALYGAVRISQRLI
MUL_1006|M.ulcerans_Agy99 DFPLPFTYPPFAAVVFYPLHLLPFGLVAFLWQLATITALYGAVRISQRLI
MLBr_01504|M.leprae_Br4923 DFPLPFTYPPFAAVVFYPLHLLPFALVAFLWQITTIAALYGAVRISQRLL
MAV_1298|M.avium_104 DFPLPFTYPPFAAIVFYPLHLLPFGLVALGWQLATIAALYGAVRISQRLL
Mflv_2153|M.gilvum_PYR-GCK DFPLPFTYPPFAAVVFYPLHVLPFGLVAFAWQIGIIAALYGVVRLSQRLL
Mvan_4550|M.vanbaalenii_PYR-1 DFPLPFTYPPFAAVVFYPLHLLPFGFVAFAWQVGIIAALYGVVRLSQRLL
MSMEG_5149|M.smegmatis_MC2_155 DFPLPFTYPPFAAIVFYPLHLLPFGVVAFIWQIGIIAALYGVVRVSQRLM
TH_0647|M.thermoresistible__bu DFPLPFTYPPFAALIFYPMHLLPFGVLGFLWQLGTIAALYGVVRLSQRLL
MAB_1304|M.abscessus_ATCC_1997 DFPLPFTYPPFAAVVFWPLHLIPFTLLGLCWILGTIAALYAVVRLSQRLL
*************::*:*:*::** .:.: * : ::***..**:****:
Mb1190|M.bovis_AF2122/97 GGTA-ETGHFAAMLWTAIAIWIEPLRSTFDYGQINVLLMLAALWAVYTPR
Rv1159|M.tuberculosis_H37Rv GGTA-ETGHFAAMLWTAIAIWIEPLRSTFDYGQINVLLMLAALWAVYTPR
MMAR_4292|M.marinum_M GVPA-ERGHRAAMVWTAVAIWIEPLRSTFDYGQINVLLMLAALWAVYTTR
MUL_1006|M.ulcerans_Agy99 GVPA-ERGHRAAMVWTAVAIWIEPLRSTFDYGQINVLLMLAALWAVYTTR
MLBr_01504|M.leprae_Br4923 GVSS-HTGHRVALLWTAIAIWIEPLRSAFDYGQINVLPMLGVLWAVYTTR
MAV_1298|M.avium_104 GVAAGAHGRRVAMVWTAVTIWIEPLRSTFDYGQVNVLLMTAVLWAVYSTR
Mflv_2153|M.gilvum_PYR-GCK GG----GDRRVAMLWTAVGIWTEPLRSTFDYGQVNVLLVLAILYAVYSTR
Mvan_4550|M.vanbaalenii_PYR-1 SPTA-VGSRRVAMLWTAVGIWTEPLRSTFDYGQVNVLLVLGVLYAVYTSK
MSMEG_5149|M.smegmatis_MC2_155 GLQ---SQRRVAMLWTALGIWTEPLRSTFDYGQVNVVLVLAVLCAVSTTR
TH_0647|M.thermoresistible__bu AGP---QDRRVAMLWTAVGIWTEPLRSTFDYGQINVVLVFAALWAVYSTR
MAB_1304|M.abscessus_ATCC_1997 GFDD----ARAAAVWTAVTMWTEPVRSTLDYGQINVLLMLLILLAVASSR
. .* :***: :* **:**::****:**: : * ** :.:
Mb1190|M.bovis_AF2122/97 WWLSGLLVGVASGVKLTPAITAVYLVGVRRLHAAAFSVVVFLATVGVSLL
Rv1159|M.tuberculosis_H37Rv WWLSGLLVGVASGVKLTPAITAVYLVGVRRLHAAAFSVVVFLATVGVSLL
MMAR_4292|M.marinum_M WWLSGLLVGVAAGIKLTPAITAVYLAGVRRWRAAVCSAIVFLVSVGVSLL
MUL_1006|M.ulcerans_Agy99 WWLSGLLVGVAAGIKLTPAITAVYLAGVRRWRAAVCSAIVFLVSVGVSLL
MLBr_01504|M.leprae_Br4923 NWLSGLLVGVAGGIKLTPAIAAVYFLGARRVRAAALSAAVFGATVAVSAL
MAV_1298|M.avium_104 WWVSALLVGLAAGIKLTPAVSGVYLAGARRWAATVFSAVIFLATIGISVL
Mflv_2153|M.gilvum_PYR-GCK WWLSGLLVGLAAGIKLTPAVAGLYFVGARRWAAVVCSAAVFLLTIGVSAL
Mvan_4550|M.vanbaalenii_PYR-1 WWLSGLVVGLAAGVKLTPAVAGLYFVGARRWATVLFSAAVFALTIGVSAL
MSMEG_5149|M.smegmatis_MC2_155 WWLSGLLVGLAAGIKLTPAVAGLYFLGARRWAAVACSAAVFFATVGVSWL
TH_0647|M.thermoresistible__bu WWLSGLLVGLAAGVKLTPAITGLYFLGARRWGAAIFSAVVFFATVGLSIL
MAB_1304|M.abscessus_ATCC_1997 WWISGTLIGLAGGVKLTPLVSGLYFLGARRWTTAIWAGVVFLLTVVVGIA
*:*. ::*:*.*:**** ::.:*: *.** :. : :* :: :.
Mb1190|M.bovis_AF2122/97 VVGDEARYYFTDLLGDAGRVGPIATSFNQSWRGAISRILGHDAGFGPLVL
Rv1159|M.tuberculosis_H37Rv VVGDEARYYFTDLLGDAGRVGPIATSFNQSWRGAISRILGHDAGFGPLVL
MMAR_4292|M.marinum_M IVGGQARYYFTDLLGDAHRVGPIATSFNQSWRGAISRILGHDAGFGPLVL
MUL_1006|M.ulcerans_Agy99 IVGGQARYYFTDLLGDAHRVGPIATSFSQSWRGAISRILGHDAGFGPLVL
MLBr_01504|M.leprae_Br4923 VVGDQARYYFTELLGDAHRVGPIATSFNQSWRGGISRIMGYDAGLGPLVL
MAV_1298|M.avium_104 VVGDQTRYYFTELLGDAHRVGPIATSFNQSWRGGLSRILGHDVGFGPLLV
Mflv_2153|M.gilvum_PYR-GCK IVGEQTRFYFTELLGDADRVGPVGTSFNQSWRGGISRILGHDAGYGPVVL
Mvan_4550|M.vanbaalenii_PYR-1 IVGDQTRMYFTELLGDADRVGPVGTSFNQSWRGGISRILGHDAGYGALVL
MSMEG_5149|M.smegmatis_MC2_155 VVGAQARRYFTELLGDADRIGPIGTSFNQSWRGGISRILGHDAGFGPLVL
TH_0647|M.thermoresistible__bu VVDQQARYYFTDLLGDADRVGPIGTSFNQSWRGGLSRVLGYDAGYGPLVL
MAB_1304|M.abscessus_ATCC_1997 VVGEQGRYYFTDLLGKPDRIGPIATVFNQSWRGGISRILGHDAGSGVLVL
:*. : * ***:***.. *:**:.* *.*****.:**::*:*.* * :::
Mb1190|M.bovis_AF2122/97 AAIASTAVLAILAWRALDRSD-----RLGKLLVVELFGLLLSPISWTHHW
Rv1159|M.tuberculosis_H37Rv AAIASTAVLAILAWRALDRSD-----RLGKLLVVELFGLLLSPISWTHHW
MMAR_4292|M.marinum_M AAIAVTAVLAVLAWRALEPAD-----HLGKLLVVELFGLLLSPISWTHHW
MUL_1006|M.ulcerans_Agy99 AAIAVTAVLAVLAWRALEPAD-----HLGKLLVVELFGLLLSPISWTHHW
MLBr_01504|M.leprae_Br4923 AAIAITAVVAVVAWRALDRPD-----RLGKLLVVELFGLLLSPISWTHHW
MAV_1298|M.avium_104 AAVAGTAVLAVLAWRALDRSD-----RLGRLIVVEVFGLLLSPISWTHHW
Mflv_2153|M.gilvum_PYR-GCK IGVAVTAVLALLAWRAIDGAQ----DRLGGIVVVQLFGLLLSPISWTHHW
Mvan_4550|M.vanbaalenii_PYR-1 VGVAVTAVLALLAWRAIGGAD----DRLGAIVIVELFGLLLSPISWTHHW
MSMEG_5149|M.smegmatis_MC2_155 IGIGITAVLALLAWRAIGGAQ----DRLGGILVVSLFGLVLSPISWTHHW
TH_0647|M.thermoresistible__bu TALALTAVLAVLAWRAIGGARGENGDRLGALVIVQLFGLLLSPISWTHHW
MAB_1304|M.abscessus_ATCC_1997 FAYAVTAILAFLAWRAVN-------DRLGQICVVEMFGLLISPISWTHHW
. . **::*.:****: :** : :*.:***::*********
Mb1190|M.bovis_AF2122/97 VWLVPLMIWLIDGPARERPGARILGWGWLVLTIVGVPWLLSFAQPSIWQI
Rv1159|M.tuberculosis_H37Rv VWLVPLMIWLIDGPARERPGARILGWGWLVLTIVGVPWLLSFAQPSIWQI
MMAR_4292|M.marinum_M VWLVPLMIWLLSGPLRDRLGARILGWGWLALTVIGVPWLLSFAQPTIWQI
MUL_1006|M.ulcerans_Agy99 VWLVPLMIWVLSGPLRDRLGARILGWGWLALTVIGVPWLLSFAQPTIWQI
MLBr_01504|M.leprae_Br4923 VWLVPLMIWLIHGPLGERPGAQIVGWGWLALSVVGVPWLLSFAQPTIWQL
MAV_1298|M.avium_104 VWLVPLMIWAIHGPVRAWRGARLVGWGWLALTVIGVPWLLSFAQPNIWQI
Mflv_2153|M.gilvum_PYR-GCK VWLIPLMIWLLHGPLRDRLGAKVLGWGWLALILVGVPWLLSFAQPTIWVI
Mvan_4550|M.vanbaalenii_PYR-1 VWLIPLMIWLLHGPLRAQLGARVLGWGWLALTLVGVPWLLSFAQPTIWVI
MSMEG_5149|M.smegmatis_MC2_155 VWLIPLMMWLLHGPLSALRGARILGWGWLALTLLGVPWLLSFAQPTIWEI
TH_0647|M.thermoresistible__bu VWLIPLMIWLIHGPLRDRVGAKVLGWGWLALTLIGVPWLLSFAQPSIWEI
MAB_1304|M.abscessus_ATCC_1997 VWMVPFMVWLLHGPWRDKVGAKVFGCGWLVLLLIGVPWLLSFAQPDIWRI
**::*:*:* : ** **::.* ***.* ::*********** ** :
Mb1190|M.bovis_AF2122/97 GRPWYLAWAGLVYVVATLATLGWIAASERYV------RIRPRRMAN--
Rv1159|M.tuberculosis_H37Rv GRPWYLAWAGLVYVVATLATLGWIAASERYV------RIRPRRMAN--
MMAR_4292|M.marinum_M GRPWYLAWAGLVYVVATLATLGWIATTRQRA------R----------
MUL_1006|M.ulcerans_Agy99 GRPWYLAWAGLVYVVATLATLGWIATTRQRA------R----------
MLBr_01504|M.leprae_Br4923 GRPWYLAWGGLVYIVVALVTLIWIVVIGKHP------VVASPR-----
MAV_1298|M.avium_104 GRPWYLAWAGLVYIVAAVATLVWIAAAGRRAG----HQVTAPSVTPA-
Mflv_2153|M.gilvum_PYR-GCK PRPWYLAWAGLIYIVATVATLAWIAIRGS-------RRCRGPSPDPSV
Mvan_4550|M.vanbaalenii_PYR-1 PRPWYLAWAGLVYIVATLATLAWVATRGS-------RRYRAPSAHPCL
MSMEG_5149|M.smegmatis_MC2_155 GRPWYLAWAGLVYIVATLATLGWIAFSR---KGSG-------------
TH_0647|M.thermoresistible__bu GRPWYLAWAGLCYVVATIATLAWIAGTRPAVTGRSVRRSPLPVPSPSR
MAB_1304|M.abscessus_ATCC_1997 DRPWPLAWAGLVDIVAAIATLTWMAVVGRRSG----HLGRLPWRHV--
*** ***.** :*.::.** *:.