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M. gilvum PYR-GCK Mflv_1892 (mscL)

annotation: large-conductance mechanosensitive channel
coordinates: 1972668 - 1973111
length: 147

LKGFKEFISRGNVIDLAVAVVVGAAFTGLVTAFTQNVVQPLVDRIGAGPDAEYGILKIPLGADQFVDLNA
VLSAAINFLIVAAVIYFVIVVPFKKIKERDAKVVSTETELTLLTEIRDLLQAQSSGTAATATDRDHTEQE
QPPAGK*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1892mscL-100% (147)large-conductance mechanosensitive channel

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1011cmscL2e-3551.97% (127) large-conductance mechanosensitive channel
M. tuberculosis H37RvRv0985cmscL2e-3551.97% (127) large-conductance mechanosensitive channel
M. leprae Br4923MLBr_00178mscL1e-3351.52% (132) large-conductance mechanosensitive channel
M. abscessus ATCC 19977MAB_1082c-7e-3753.44% (131) large-conductance mechanosensitive channel
M. marinum MMMAR_4525mscL7e-3748.61% (144) large-conductance ion mechanosensitive channel MscL
M. avium 104MAV_1098mscL4e-3753.85% (130) large-conductance mechanosensitive channel
M. smegmatis MC2 155MSMEG_5482mscL1e-4974.62% (130) large-conductance mechanosensitive channel
M. thermoresistible (build 8)TH_0943mscL2e-4159.69% (129) POSSIBLE LARGE-CONDUCTANCE ION MECHANOSENSITIVE CHANNEL MSCL
M. ulcerans Agy99MUL_4697mscL5e-3748.61% (144) large-conductance mechanosensitive channel
M. vanbaalenii PYR-1Mvan_4838mscL4e-5986.82% (129) large-conductance mechanosensitive channel

CLUSTAL 2.0.9 multiple sequence alignment


Mb1011c|M.bovis_AF2122/97           MLKGFKEFLARGNIVDLAVAVVIGTAFTALVTKFTDSIITPLINRIGVNA
Rv0985c|M.tuberculosis_H37Rv        MLKGFKEFLARGNIVDLAVAVVIGTAFTALVTKFTDSIITPLINRIGVNA
MMAR_4525|M.marinum_M               MLKGFKEFLSRGNIVDLAVAVVIGTAFTALVTRFTDSIITPLINRVGVNE
MUL_4697|M.ulcerans_Agy99           MLKGFKEFLSRGNIVDLAVAVVIGTAFTALVTRFTDSIITPLINRVGVNE
MAV_1098|M.avium_104                MLKGFKEFLSRGNIIDLSTAVVIGTAFTALVTTFTDSIIKPLINRIGVNQ
MLBr_00178|M.leprae_Br4923          MFRGFKEFLSRGNIVDLAVAVVIGTAFTALITKFTDSIITPLINRVGVNQ
MAB_1082c|M.abscessus_ATCC_199      MLKGFRDFLLRGNVIDLAVAVVIGAAFTALVTKFSDAIIQPLINRIGTGP
TH_0943|M.thermoresistible__bu      MLKGFKEFLARGNIVDLAVAVVIGTAFTGLVTRFTDSVIQPLINRIGATG
Mflv_1892|M.gilvum_PYR-GCK          MLKGFKEFISRGNVIDLAVAVVVGAAFTGLVTAFTQNVVQPLVDRIGAGP
Mvan_4838|M.vanbaalenii_PYR-1       MLKGFKEFISRGNVIDLAVAVVIGAAFTGLVTAFTENVIQPLIDRIGAGP
MSMEG_5482|M.smegmatis_MC2_155      MLKGFKEFLSRGNVIDLAVAVVIGAAFTGLVTAFTEKVIQPLIDRIGAGG
                                    *::**::*: ***::**:.***:*:***.*:* *:: :: **::*:*.  

Mb1011c|M.bovis_AF2122/97           QSDVGILRIGIGGG--QTIDLNVLLSAAINFFLIAFAVYFLVVLPYNTLR
Rv0985c|M.tuberculosis_H37Rv        QSDVGILRIGIGGG--QTIDLNVLLSAAINFFLIAFAVYFLVVLPYNTLR
MMAR_4525|M.marinum_M               QSDLGILKIGIGRG--QSIDLNVLLSATINFILVAGVVYFLVVVPYNTLR
MUL_4697|M.ulcerans_Agy99           QSDLGILKIGIGRG--QSIDLNVLLSATINFILVAGVVYFLVVVPYNTLR
MAV_1098|M.avium_104                KSDIGILRISIGGG--QTIDLNNVLSAAINFVIIAAVVYFLVVLPYTTLR
MLBr_00178|M.leprae_Br4923          QTNISPLRIDIGGD--QAIDLNIVLSAAINFLLIALVVYFLVVLPYTTIR
MAB_1082c|M.abscessus_ATCC_199      DSDHPALKVGIGGG--QYLDFNVLVTATINFVLIAAVVYFLVVLPYNTIK
TH_0943|M.thermoresistible__bu      ETDIGVLRIPIGGD--QAIDLNILLSALINFVIVAAVVYFLVVLPYNKLR
Mflv_1892|M.gilvum_PYR-GCK          DAEYGILKIPLGAD--QFVDLNAVLSAAINFLIVAAVIYFVIVVPFKKIK
Mvan_4838|M.vanbaalenii_PYR-1       DAEYGILRIPLGGD--QFVDLNAVLSAAVNFLIVAAVIYFVIVVPFKKLK
MSMEG_5482|M.smegmatis_MC2_155      EREYGILKIPLGGDPEQFVDLNAVLSAAINFLIVAAVLYFVIMLPYKKLR
                                    . :   *:: :* .  * :*:* :::* :**.::* .:**::::*:..::

Mb1011c|M.bovis_AF2122/97           K---KGEVEQPG----DTQVVLLTEIRDLLAQTNGDSPGRHGGR---GTP
Rv0985c|M.tuberculosis_H37Rv        K---KGEVEQPG----DTQVVLLTEIRDLLAQTNGDSPGRHGGR---GTP
MMAR_4525|M.marinum_M               K---KGEVEQAD----DAQIVLLTEIRDLLAQTNSNSSGRHEAPGTAGTP
MUL_4697|M.ulcerans_Agy99           K---KGEVEQAD----DAQIVLLTEIRDLLAQTNSNSSGRHEAPGTAGTP
MAV_1098|M.avium_104                K---RGEVEPAD----DAQVVLLTEIRDLLAQTNGDSSGKHGSVS--TTP
MLBr_00178|M.leprae_Br4923          K---HGEVEQFDTDLIGNQVVLLAEIRDLLAQSNGAPSGRHVDTAD-LTP
MAB_1082c|M.abscessus_ATCC_199      ERLAKSGEEPAA----QTEAELLVEIRDLLAEQKKAS-------------
TH_0943|M.thermoresistible__bu      A---RGEVEQAQ----DTELSLLTEIRDLLADTNG-SSGKHVSGPG-TGP
Mflv_1892|M.gilvum_PYR-GCK          E---RDAKVVST----ETELTLLTEIRDLLQAQSSG-----TAATA-TDR
Mvan_4838|M.vanbaalenii_PYR-1       E---RDKKVEST----ETELTLLTEIRDLLRDN--------AADAA-TGR
MSMEG_5482|M.smegmatis_MC2_155      E---RGEVEQAQ----DTELSILTEIRDLLAENSNGSTGKHVSGPG-TGP
                                        :.            :  :*.******                    

Mb1011c|M.bovis_AF2122/97           SPTDGPRASTESQ-
Rv0985c|M.tuberculosis_H37Rv        SPTDGPRASTESQ-
MMAR_4525|M.marinum_M               PPNYGPRADT----
MUL_4697|M.ulcerans_Agy99           PPNYGPRADT----
MAV_1098|M.avium_104                PPEYGPRAEAES--
MLBr_00178|M.leprae_Br4923          TPNHEPRADT----
MAB_1082c|M.abscessus_ATCC_199      --------------
TH_0943|M.thermoresistible__bu      SPDTAETTSADRT-
Mflv_1892|M.gilvum_PYR-GCK          DHTEQEQPPAGK--
Mvan_4838|M.vanbaalenii_PYR-1       HGGTGPQSHADE--
MSMEG_5482|M.smegmatis_MC2_155      SPDTATYTSGDRTS