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FRGFKEFLSRGNIVDLAVAVVIGTAFTALITKFTDSIITPLINRVGVNQQTNISPLRIDIGGDQAIDLNI VLSAAINFLLIALVVYFLVVLPYTTIRKHGEVEQFDTDLIGNQVVLLAEIRDLLAQSNGAPSGRHVDTAD LTPTPNHEPRADT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00178 | mscL | - | 100% (154) | large-conductance mechanosensitive channel |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1011c | mscL | 9e-53 | 70.97% (155) | large-conductance mechanosensitive channel |
| M. gilvum PYR-GCK | Mflv_1892 | mscL | 4e-33 | 51.52% (132) | large-conductance mechanosensitive channel |
| M. tuberculosis H37Rv | Rv0985c | mscL | 9e-53 | 70.97% (155) | large-conductance mechanosensitive channel |
| M. abscessus ATCC 19977 | MAB_1082c | - | 1e-34 | 54.81% (135) | large-conductance mechanosensitive channel |
| M. marinum M | MMAR_4525 | mscL | 6e-53 | 69.03% (155) | large-conductance ion mechanosensitive channel MscL |
| M. avium 104 | MAV_1098 | mscL | 2e-52 | 69.28% (153) | large-conductance mechanosensitive channel |
| M. smegmatis MC2 155 | MSMEG_5482 | mscL | 4e-39 | 53.33% (150) | large-conductance mechanosensitive channel |
| M. thermoresistible (build 8) | TH_0943 | mscL | 7e-47 | 65.54% (148) | POSSIBLE LARGE-CONDUCTANCE ION MECHANOSENSITIVE CHANNEL MSCL |
| M. ulcerans Agy99 | MUL_4697 | mscL | 4e-53 | 69.03% (155) | large-conductance mechanosensitive channel |
| M. vanbaalenii PYR-1 | Mvan_4838 | mscL | 3e-35 | 51.77% (141) | large-conductance mechanosensitive channel |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1011c|M.bovis_AF2122/97 MLKGFKEFLARGNIVDLAVAVVIGTAFTALVTKFTDSIITPLINRIGVNA
Rv0985c|M.tuberculosis_H37Rv MLKGFKEFLARGNIVDLAVAVVIGTAFTALVTKFTDSIITPLINRIGVNA
MMAR_4525|M.marinum_M MLKGFKEFLSRGNIVDLAVAVVIGTAFTALVTRFTDSIITPLINRVGVNE
MUL_4697|M.ulcerans_Agy99 MLKGFKEFLSRGNIVDLAVAVVIGTAFTALVTRFTDSIITPLINRVGVNE
MAV_1098|M.avium_104 MLKGFKEFLSRGNIIDLSTAVVIGTAFTALVTTFTDSIIKPLINRIGVNQ
MLBr_00178|M.leprae_Br4923 MFRGFKEFLSRGNIVDLAVAVVIGTAFTALITKFTDSIITPLINRVGVNQ
MAB_1082c|M.abscessus_ATCC_199 MLKGFRDFLLRGNVIDLAVAVVIGAAFTALVTKFSDAIIQPLINRIGTGP
TH_0943|M.thermoresistible__bu MLKGFKEFLARGNIVDLAVAVVIGTAFTGLVTRFTDSVIQPLINRIGATG
Mflv_1892|M.gilvum_PYR-GCK MLKGFKEFISRGNVIDLAVAVVVGAAFTGLVTAFTQNVVQPLVDRIGAGP
Mvan_4838|M.vanbaalenii_PYR-1 MLKGFKEFISRGNVIDLAVAVVIGAAFTGLVTAFTENVIQPLIDRIGAGP
MSMEG_5482|M.smegmatis_MC2_155 MLKGFKEFLSRGNVIDLAVAVVIGAAFTGLVTAFTEKVIQPLIDRIGAGG
*::**::*: ***::**:.***:*:***.*:* *:: :: **::*:*.
Mb1011c|M.bovis_AF2122/97 QSDVGILRIGIGGG--QTIDLNVLLSAAINFFLIAFAVYFLVVLPYNTLR
Rv0985c|M.tuberculosis_H37Rv QSDVGILRIGIGGG--QTIDLNVLLSAAINFFLIAFAVYFLVVLPYNTLR
MMAR_4525|M.marinum_M QSDLGILKIGIGRG--QSIDLNVLLSATINFILVAGVVYFLVVVPYNTLR
MUL_4697|M.ulcerans_Agy99 QSDLGILKIGIGRG--QSIDLNVLLSATINFILVAGVVYFLVVVPYNTLR
MAV_1098|M.avium_104 KSDIGILRISIGGG--QTIDLNNVLSAAINFVIIAAVVYFLVVLPYTTLR
MLBr_00178|M.leprae_Br4923 QTNISPLRIDIGGD--QAIDLNIVLSAAINFLLIALVVYFLVVLPYTTIR
MAB_1082c|M.abscessus_ATCC_199 DSDHPALKVGIGGG--QYLDFNVLVTATINFVLIAAVVYFLVVLPYNTIK
TH_0943|M.thermoresistible__bu ETDIGVLRIPIGGD--QAIDLNILLSALINFVIVAAVVYFLVVLPYNKLR
Mflv_1892|M.gilvum_PYR-GCK DAEYGILKIPLGAD--QFVDLNAVLSAAINFLIVAAVIYFVIVVPFKKIK
Mvan_4838|M.vanbaalenii_PYR-1 DAEYGILRIPLGGD--QFVDLNAVLSAAVNFLIVAAVIYFVIVVPFKKLK
MSMEG_5482|M.smegmatis_MC2_155 EREYGILKIPLGGDPEQFVDLNAVLSAAINFLIVAAVLYFVIMLPYKKLR
. : *:: :* . * :*:* :::* :**.::* .:**::::*:..::
Mb1011c|M.bovis_AF2122/97 K---KGEVEQPG----DTQVVLLTEIRDLLAQTNGDSPGRHGGR---GTP
Rv0985c|M.tuberculosis_H37Rv K---KGEVEQPG----DTQVVLLTEIRDLLAQTNGDSPGRHGGR---GTP
MMAR_4525|M.marinum_M K---KGEVEQAD----DAQIVLLTEIRDLLAQTNSNSSGRHEAPGTAGTP
MUL_4697|M.ulcerans_Agy99 K---KGEVEQAD----DAQIVLLTEIRDLLAQTNSNSSGRHEAPGTAGTP
MAV_1098|M.avium_104 K---RGEVEPAD----DAQVVLLTEIRDLLAQTNGDSSGKHGSVS--TTP
MLBr_00178|M.leprae_Br4923 K---HGEVEQFDTDLIGNQVVLLAEIRDLLAQSNGAPSGRHVDTAD-LTP
MAB_1082c|M.abscessus_ATCC_199 ERLAKSGEEPAA----QTEAELLVEIRDLLAEQKKAS-------------
TH_0943|M.thermoresistible__bu A---RGEVEQAQ----DTELSLLTEIRDLLADTNG-SSGKHVSGPG-TGP
Mflv_1892|M.gilvum_PYR-GCK E---RDAKVVST----ETELTLLTEIRDLLQAQSSG-----TAATA-TDR
Mvan_4838|M.vanbaalenii_PYR-1 E---RDKKVEST----ETELTLLTEIRDLLRDN--------AADAA-TGR
MSMEG_5482|M.smegmatis_MC2_155 E---RGEVEQAQ----DTELSILTEIRDLLAENSNGSTGKHVSGPG-TGP
:. : :*.******
Mb1011c|M.bovis_AF2122/97 SPTDGPRASTESQ-
Rv0985c|M.tuberculosis_H37Rv SPTDGPRASTESQ-
MMAR_4525|M.marinum_M PPNYGPRADT----
MUL_4697|M.ulcerans_Agy99 PPNYGPRADT----
MAV_1098|M.avium_104 PPEYGPRAEAES--
MLBr_00178|M.leprae_Br4923 TPNHEPRADT----
MAB_1082c|M.abscessus_ATCC_199 --------------
TH_0943|M.thermoresistible__bu SPDTAETTSADRT-
Mflv_1892|M.gilvum_PYR-GCK DHTEQEQPPAGK--
Mvan_4838|M.vanbaalenii_PYR-1 HGGTGPQSHADE--
MSMEG_5482|M.smegmatis_MC2_155 SPDTATYTSGDRTS