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M. gilvum PYR-GCK Mflv_1622 (-)

annotation: beta-lactamase domain-containing protein
coordinates: 1693832 - 1694482
length: 216

QLTHFGHSCLLASFTGQGPDTSVLFDPGAFSHGFEGITGLAAILITHQHPDHVDVERLPALIEANPQAAL
YADPQTAAQLGGPWQAVNVGDELSIGHLTVRGAGGTHAVIHPEIPVIDNISYLVGDGEHPARLMHPGDAL
FVPDEPVDVLATPAAAPWLKISEAVDYLRAVAPTHAVPIHQAIIDPIGRPIFYGRLTEMTDTDFQVLEQE
NAVTF*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1622--100% (216)beta-lactamase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0809c-4e-5579.07% (129) hypothetical protein Mb0809c
M. tuberculosis H37RvRv0786c-4e-5579.07% (129) hypothetical protein Rv0786c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0696c-3e-9473.15% (216) hypothetical protein MAB_0696c
M. marinum MMMAR_4901-4e-9579.17% (216) Zn-dependent hydrolase
M. avium 104MAV_0733-7e-9778.70% (216) metallo-beta-lactamase superfamily protein, putative
M. smegmatis MC2 155MSMEG_5834-2e-9779.25% (212) metallo-beta-lactamase superfamily protein
M. thermoresistible (build 8)TH_0565-1e-9686.01% (193) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5131-1e-11389.40% (217) beta-lactamase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1622|M.gilvum_PYR-GCK          ---------------------------------------MQLTHFGHSCL
Mvan_5131|M.vanbaalenii_PYR-1       --------------------------------------MLQLTHFGHSCL
MSMEG_5834|M.smegmatis_MC2_155      MGAAPAGTATSVVAASPAAASNVAQINRMNPPTEGNNIEMQLTHFGHSCL
TH_0565|M.thermoresistible__bu      --------------------------------------------------
Mb0809c|M.bovis_AF2122/97           --------------------------------------------------
Rv0786c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4901|M.marinum_M               ---------------------------------------MQLTHFGHSCL
MAV_0733|M.avium_104                ---------------------------------------MQLTHFGHSCL
MAB_0696c|M.abscessus_ATCC_199      ---------------------------------------MQLTHFGHSCL
                                                                                      

Mflv_1622|M.gilvum_PYR-GCK          LASFT-GQGPDTSVLFDPGAFSHGFEGITGLAAILITHQHPDHVDVERLP
Mvan_5131|M.vanbaalenii_PYR-1       LASFDDGSGAQTTVLFDPGNFSHGFEGITGLDAILITHQHPDHADTARLP
MSMEG_5834|M.smegmatis_MC2_155      LATIS-----DTTVLFDPGNFSHGFEGITGLSAILITHQHPDHADTTRLP
TH_0565|M.thermoresistible__bu      -------------VLFDPGIFSHGFEGITGLSAILITHQHPDHADTERLP
Mb0809c|M.bovis_AF2122/97           --------------------------------------------------
Rv0786c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4901|M.marinum_M               LADFG-----QTRVLFDPGTFAHGFEGITGLAAILITHQHPDHVDVSRLP
MAV_0733|M.avium_104                LAEFD-----HTRVLFDPGTFAHGFEGITGLTAILITHQHPDHIDATRLP
MAB_0696c|M.abscessus_ATCC_199      LAEFP-SENGNTTLLFDPGNFSHGFEGITGLSAILITHQHPDHVDLQRLP
                                                                                      

Mflv_1622|M.gilvum_PYR-GCK          ALIEANPQAALYADPQTAAQLGGPWQAVNVGDELSIGHLTVRGAGGTHAV
Mvan_5131|M.vanbaalenii_PYR-1       ALVEANPQAALFADPQTAAQLGGSWQAVNVGDQLSIGHLTVRGAGGTHAV
MSMEG_5834|M.smegmatis_MC2_155      ALLDANPQAKLYADPQTAAQLGEPWTAVHVGDEFTIGSINVRGVGGKHAV
TH_0565|M.thermoresistible__bu      ALLEANPQAKLYADPQTAAQLGEPWQPVHVGDEFTIGHLTVRGAGGRHAV
Mb0809c|M.bovis_AF2122/97           ---------------------------MHVGDELPLAELTVRAVGGCHAV
Rv0786c|M.tuberculosis_H37Rv        ---------------------------MHVGDELPLAELTVRAVGGCHAV
MMAR_4901|M.marinum_M               ALLAANPDAALYADAQTAAVLGTECREVHVGDELAVGELTIRAVGGRHAV
MAV_0733|M.avium_104                ALLEGNPDAALYADPQTTAQLGAPCRAVHVGDELQIGELTVRAVGGKHAV
MAB_0696c|M.abscessus_ATCC_199      ALVEANPGAALYADPMTAAQLGGPWQAVHAGDNFTVADLTVRGVGGQHAV
                                                               ::.**:: :. :.:*..** ***

Mflv_1622|M.gilvum_PYR-GCK          IHPEIPVIDNISYLVGDGEHPARLMHPGDALFVPDEPVDVLATPAAAPWL
Mvan_5131|M.vanbaalenii_PYR-1       IHPEIPVIDNISYLVGDGEHPAKLMHPGDALFVPGEPVDVLATPAAAPWM
MSMEG_5834|M.smegmatis_MC2_155      IHPEIPVIDNISYLLGDDEHPARFMHPGDALFVPGEPVDVLATPAAAPWM
TH_0565|M.thermoresistible__bu      IHPELPVIDNISYLIGDGEHPARLMHPGDALFTPGEPVDVLATPAAAPWL
Mb0809c|M.bovis_AF2122/97           IHPEIPVIENISYLVGDSKHRARLMHPGDALFVPGEQVDVLATPAAAPWM
Rv0786c|M.tuberculosis_H37Rv        IHPEIPVIENISYLVGDSKHRARLMHPGDALFVPGEQVDVLATPAAAPWM
MMAR_4901|M.marinum_M               IHPEIPVIENISYLVGDGDHRARLMHPGDALFVPDEPVDVLATPAAAPWM
MAV_0733|M.avium_104                IHPEIPVIENISFLVGDGGHRARLMHPGDALFVPDEPVDVLATPAAAPWM
MAB_0696c|M.abscessus_ATCC_199      IHPEIPLIDNTSYLIGDAEHAARLMHPGDALFAPGEDVDVLALPAAAPWM
                                    ****:*:*:* *:*:**  * *::********.*.* ***** ******:

Mflv_1622|M.gilvum_PYR-GCK          KISEAVDYLRAVAPTHAVPIHQAIIDPIGRPIFYGRLTEMTDTDFQVLEQ
Mvan_5131|M.vanbaalenii_PYR-1       KISEAIDYLRAVAPVHAVPIHQAIIDPIGRPIFYGRLTEMTDTDFRVLEQ
MSMEG_5834|M.smegmatis_MC2_155      KVSEAVDYLRAVAPRAAVPIHQGIIAPDARGVFYGRLSEMTSTDFQVLQE
TH_0565|M.thermoresistible__bu      KISEAVDYLRAVAPNRAVPIHQAIIDPSARGIFYSRLQEMTDTDFQVLKE
Mb0809c|M.bovis_AF2122/97           KISEAVDYLRAVAPARAVPIHQAIVAPDARGIYYGRLTEMTTTDFQVLPE
Rv0786c|M.tuberculosis_H37Rv        KISEAVDYLRAVAPARAVPIHQAIVAPDARGIYYGRLTEMTTTDFQVLPE
MMAR_4901|M.marinum_M               KISEAVDYLRSVAPARAVPIHQGIIATEARGIYYGRLAEMTDTDFQVLPE
MAV_0733|M.avium_104                KVSEAVDYLRAVAPARAVPIHQGIIAPDARGIYYGRLSEMTSTDFQVLPE
MAB_0696c|M.abscessus_ATCC_199      KVSEAIEYLRAVNPARAVPIHQGILQEAAYPFYYTRFREMSDADFQVLPQ
                                    *:***::***:* *  ******.*:   .  .:* *: **: :**:** :

Mflv_1622|M.gilvum_PYR-GCK          ENAVTF
Mvan_5131|M.vanbaalenii_PYR-1       ESAVTF
MSMEG_5834|M.smegmatis_MC2_155      ENGTEV
TH_0565|M.thermoresistible__bu      ENATQF
Mb0809c|M.bovis_AF2122/97           ESAVTF
Rv0786c|M.tuberculosis_H37Rv        ESAVTF
MMAR_4901|M.marinum_M               ESAVTF
MAV_0733|M.avium_104                EDAVTF
MAB_0696c|M.abscessus_ATCC_199      EDAVTF
                                    *... .