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VPAHTADLYSGDIKSVLLSEDQIRAKTAELAALIADDYQDRESGQDLLLITVLKGAVMFVTDLARAIPLP TQLEFMAVSSYGSSTSSSGVVRILKDLDRDINGRDVLIVEDIIDSGLTLSWLLRNLATRGPKSLRVCTLL RKPEAVRAELDVEYIGFDIPNEFVVGYGLDYAERYRDLPYIGTLDPKVYKP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1412 | - | - | 100% (191) | hypoxanthine phosphoribosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3648c | hpt | 1e-80 | 75.92% (191) | hypoxanthine-guanine phosphoribosyltransferase |
| M. tuberculosis H37Rv | Rv3624c | hpt | 1e-80 | 75.92% (191) | hypoxanthine-guanine phosphoribosyltransferase |
| M. leprae Br4923 | MLBr_00214 | hpt | 1e-81 | 76.96% (191) | putative hypoxanthine phosphoribosyltransferase |
| M. abscessus ATCC 19977 | MAB_0523 | - | 2e-76 | 77.35% (181) | hypoxanthine phosphoribosyltransferase (HPT) |
| M. marinum M | MMAR_5124 | hpt | 1e-80 | 78.01% (191) | hypoxanthine-guanine phosphoribosyltransferase Hpt |
| M. avium 104 | MAV_0532 | hpt | 5e-82 | 78.53% (191) | hypoxanthine phosphoribosyltransferase |
| M. smegmatis MC2 155 | MSMEG_6110 | hpt | 2e-87 | 83.60% (189) | hypoxanthine phosphoribosyltransferase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4200 | hpt | 2e-81 | 78.53% (191) | hypoxanthine-guanine phosphoribosyltransferase Hpt |
| M. vanbaalenii PYR-1 | Mvan_5377 | - | 5e-95 | 90.00% (190) | hypoxanthine phosphoribosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0523|M.abscessus_ATCC_1997 --------------------MTCEQDQACGEQYSGDVKSVLLTEEQIRAK
MSMEG_6110|M.smegmatis_MC2_155 ----------------------MDVAVESTEMYPGDIKSVLLSEEQIRTR
Mflv_1412|M.gilvum_PYR-GCK ------------------------MPAHTADLYSGDIKSVLLSEDQIRAK
Mvan_5377|M.vanbaalenii_PYR-1 ----------------------MHVPTRTAELYPGDIKSVLLSEEQIKAK
Mb3648c|M.bovis_AF2122/97 MTPALVVGPAAWHAVHVTQSSSAITPGQTAELYPGDIKSVLLTAEQIQAR
Rv3624c|M.tuberculosis_H37Rv MTPALVVGPAAWHAVHVTQSSSAITPGQTAELYPGDIKSVLLTAEQIQAR
MMAR_5124|M.marinum_M --------------MHVAQSSSAITPGHAGELYPGDIKSVLLTEEQIQRR
MUL_4200|M.ulcerans_Agy99 --------------MHVAQSSSAITPGHTGELYPGDIKSVLLTEEQIQRR
MAV_0532|M.avium_104 --------------MGVAQISSAITPAQPAELYPGDIKSVLLTAEQIQAR
MLBr_00214|M.leprae_Br4923 ----MVFRRAAWHALLVAQSFSAINPGPTAELYLGDIKSVMLTQEQIQAR
: * **:***:*: :**: :
MAB_0523|M.abscessus_ATCC_1997 TQELGAAIGEKYRDIEG----DLLLVTVLKGAVMFVSDLARAIPIPTQME
MSMEG_6110|M.smegmatis_MC2_155 TAELAAAIADQYRDNLGDD--DLLLVTVLKGAVMFVTDLARSIPLPTQLE
Mflv_1412|M.gilvum_PYR-GCK TAELAALIADDYQDR--ESGQDLLLITVLKGAVMFVTDLARAIPLPTQLE
Mvan_5377|M.vanbaalenii_PYR-1 TAELAAQIAGDYQDA--ESGQDLLLVTVLKGAVMFVTDLARAIPVPTQLE
Mb3648c|M.bovis_AF2122/97 IAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFE
Rv3624c|M.tuberculosis_H37Rv IAELGEQIGNDYRELSATTGQDLLLITVLKGAVLFVTDLARAIPVPTQFE
MMAR_5124|M.marinum_M IDELAAQIGNDYRELADTSDQDLLLITVLKGAVLFVTDLARAIPLPTQFE
MUL_4200|M.ulcerans_Agy99 IDELAAQIGNDYRELVDTSDQDLLLITVLKGAVLFVTDLARAIPLPTQFE
MAV_0532|M.avium_104 IAELGREIGDNYRDAAAETGQDLLLITVLKGAVIFVTDLARAIPLPTQFE
MLBr_00214|M.leprae_Br4923 IAELGAQIGHDYRDRSPASDQDLLLVTVLKGAVIFVTDLARAIPLPTQFE
**. *. .*:: ****:*******:**:****:**:***:*
MAB_0523|M.abscessus_ATCC_1997 FMAVSSYGSATSSSGVVRILKDLDRDIQNLDVLIVEDIIDSGLTLSWLMR
MSMEG_6110|M.smegmatis_MC2_155 FMAVSSYGSSTSSSGVVRILKDLDRDINDRDVLIVEDIIDSGLTLSWLLR
Mflv_1412|M.gilvum_PYR-GCK FMAVSSYGSSTSSSGVVRILKDLDRDINGRDVLIVEDIIDSGLTLSWLLR
Mvan_5377|M.vanbaalenii_PYR-1 FMAVSSYGSSTSSSGVVRILKDLDRDINDRDVLIVEDIVDSGLTLSWLLR
Mb3648c|M.bovis_AF2122/97 FMAVSSYGSSTSSSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSR
Rv3624c|M.tuberculosis_H37Rv FMAVSSYGSSTSSSGVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSR
MMAR_5124|M.marinum_M FMAVSSYGSSTSSSGVVRILKDLDRDIAGRDVLIVEDVVDSGLTLSWLLR
MUL_4200|M.ulcerans_Agy99 FMAVSSYGSSTSSSGVVRILKDLDRDIAGRDVLIVEDVVDSGLTLSWLLR
MAV_0532|M.avium_104 FMAVSSYGSSTSSSGVVRILKDLDRDIQGRDVLIVEDVVDSGLTLSWLLR
MLBr_00214|M.leprae_Br4923 FMAVSSYGSSMSSSGVVRILKDLDRDIHDRNVLIVEDVVDSGLTLSWLLR
*********: **************** . :******::********* *
MAB_0523|M.abscessus_ATCC_1997 NLASRGPRSLNVVSLLRKPEAKKVDVDVALVGFEIPNEFVVGYGLDYGER
MSMEG_6110|M.smegmatis_MC2_155 NLATRHPRSLKVCTLLRKPEAVRTDIDVEYVGFDIPNEFVVGYGLDYAER
Mflv_1412|M.gilvum_PYR-GCK NLATRGPKSLRVCTLLRKPEAVRAELDVEYIGFDIPNEFVVGYGLDYAER
Mvan_5377|M.vanbaalenii_PYR-1 NLATRGPRSLRVCTLLRKPEAVRADVDISYIGFDIPNEFVVGYGLDYAER
Mb3648c|M.bovis_AF2122/97 NLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDER
Rv3624c|M.tuberculosis_H37Rv NLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDER
MMAR_5124|M.marinum_M NLKSRQPKSLRVCTLLRKPEAVGANVDITYVGFDISNDFVVGYGLDYDER
MUL_4200|M.ulcerans_Agy99 NLKSRQPKSLRVCTLLRKPEAVGANVDITYVGFDISNDFVVGYGLDYDER
MAV_0532|M.avium_104 NLSTRHPRSLRVCTLLRKPDARGAHVDIAYVGFDIPNDFVVGYGLDYDER
MLBr_00214|M.leprae_Br4923 NLATRRPQSLQVCTLLRKPDALRANVDITYVGFDIPNDFVVGYGLDYDER
** :* *:**.* :*****:* ..::: :**:*.*:********* **
MAB_0523|M.abscessus_ATCC_1997 YRDLPFIGTLHPRVYTD-
MSMEG_6110|M.smegmatis_MC2_155 YRDLPFIGLLDPKVYTH-
Mflv_1412|M.gilvum_PYR-GCK YRDLPYIGTLDPKVYKP-
Mvan_5377|M.vanbaalenii_PYR-1 YRDLPYIGTLDPKVYEQT
Mb3648c|M.bovis_AF2122/97 YRDLSYIGTLDPRVYQ--
Rv3624c|M.tuberculosis_H37Rv YRDLSYIGTLDPRVYQ--
MMAR_5124|M.marinum_M YRDLSYIGTLDPRVYQ--
MUL_4200|M.ulcerans_Agy99 YRDLSYIGTLDPRVYQ--
MAV_0532|M.avium_104 YRDLSYIGTLDPRVYQQ-
MLBr_00214|M.leprae_Br4923 YRDLPYIGMLDPRVYQQ-
****.:** *.*:**