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GRTAAVIWHASFSIAAGVLYFFFVLPRTPELLGDTSHTLGTALRIVAGALIGLAALPVVFTLLRTRRPEF GTPKLALNLRTASIALHVLAAALIVGTAISEIWLSVDSAGQWLFGIYGAAAAIGLLGIFAFYLAFVAELP PPPPKPLKATKRTGRGRKGDGSEDSADVEGSEGEVLESERTDGVTDADVDTGENGVKAEDAPAAVSDADD ADDADGKLRNRRPTGKGTGLGRRKRTRGGVAVED*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1279 | - | - | 100% (245) | hypothetical protein Mflv_1279 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3750 | - | 2e-77 | 60.87% (253) | transmembrane protein |
| M. tuberculosis H37Rv | Rv3723 | - | 2e-77 | 60.87% (253) | transmembrane protein |
| M. leprae Br4923 | MLBr_02337 | - | 1e-66 | 54.37% (252) | hypothetical protein MLBr_02337 |
| M. abscessus ATCC 19977 | MAB_0283c | - | 1e-44 | 48.44% (225) | hypothetical protein MAB_0283c |
| M. marinum M | MMAR_5242 | - | 5e-78 | 56.74% (282) | hypothetical protein MMAR_5242 |
| M. avium 104 | MAV_0378 | - | 1e-84 | 62.50% (264) | hypothetical protein MAV_0378 |
| M. smegmatis MC2 155 | MSMEG_6288 | - | 1e-69 | 51.19% (293) | hypothetical protein MSMEG_6288 |
| M. thermoresistible (build 8) | TH_1678 | - | 2e-75 | 62.95% (251) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4318 | - | 3e-78 | 57.88% (273) | hypothetical protein MUL_4318 |
| M. vanbaalenii PYR-1 | Mvan_5536 | - | 3e-96 | 70.70% (256) | hypothetical protein Mvan_5536 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3750|M.bovis_AF2122/97 --MGRKVAVL----WHASFSIGAGVLYFYFVLPRWPELMGDTGHSLGTGL
Rv3723|M.tuberculosis_H37Rv --MGRKVAVL----WHASFSIGAGVLYFYFVLPRWPELMGDTGHSLGTGL
MLBr_02337|M.leprae_Br4923 --MGYKVATL----WHASFSIGAGVLYFYFVLPRWPELIGETTHTLGTTL
MMAR_5242|M.marinum_M --MGRKVAML----WHASFSIGAGVLYFFFVLPRWPELMGDTAHSLGTGL
MUL_4318|M.ulcerans_Agy99 --MGRKVAML----WHASFSIGAGVLYFFFVVPRWPELMGDTAHSLGTGL
MAV_0378|M.avium_104 --MGRKVAIP----WHASFSIAAGVLYFFFVLPRWPELMGDTTHSLGTAL
Mflv_1279|M.gilvum_PYR-GCK --MGRTAAVI----WHASFSIAAGVLYFFFVLPRTPELLGDTSHTLGTAL
Mvan_5536|M.vanbaalenii_PYR-1 --MGRTVAVI----WHASFSIAAGVLYFFFVLPRTPELVGDTSPTLGTVL
TH_1678|M.thermoresistible__bu --MRRTGAVL----WHASFSVIAAVLYFFFVLPRWFELTGQLSETLGTVL
MSMEG_6288|M.smegmatis_MC2_155 --MGRTVAVT----WHVASTLIAAGLFFFFVIPRWPELMGETSPTLGTVL
MAB_0283c|M.abscessus_ATCC_199 MAAGRRTATIVLTSSHAALSLIAGLLFFFFVLPRWPELNGATGHTFGTGM
* *.: :: *. *:*:**:** ** * ::** :
Mb3750|M.bovis_AF2122/97 RIATGALVGLAALPVVFTLLRTRKPELGTPQLALSMRIWSIMAHVLAGAL
Rv3723|M.tuberculosis_H37Rv RIATGALVGLAALPVVFTLLRTRKPELGTPQLALSMRIWSIMAHVLAGAL
MLBr_02337|M.leprae_Br4923 RIVTGVLFGLAALPVVFTLLRSQTSELGIPQLALSIRTWSIVAHVLSGVL
MMAR_5242|M.marinum_M RITAGALFGLAALPVVFTLLRTRKPELGTPALALSIRTWSIVAHVLAGVL
MUL_4318|M.ulcerans_Agy99 RITAGALFGLAALPVVFTLLRTRKPELGTPALALSIRTWSIVAHVLAGVL
MAV_0378|M.avium_104 RIVAGVLAALAALPVVFTLLRTRKPELGTPQLALSLRVASIVAHVLAGLL
Mflv_1279|M.gilvum_PYR-GCK RIVAGALIGLAALPVVFTLLRTRRPEFGTPKLALNLRTASIALHVLAAAL
Mvan_5536|M.vanbaalenii_PYR-1 RVVVGALIGLAALPVVFTLLRTRRPEFGTPQMALNLRTTSIALHVLSGVL
TH_1678|M.thermoresistible__bu RIVTGVLIGLAALPVVFTLLRTRRPEFGTPQLALTLRTVSIALHVLAGVL
MSMEG_6288|M.smegmatis_MC2_155 RIVTGVLVALTALPVVFTLLRTRRPELGTPELALRLRTTSIVFHVLAGVL
MAB_0283c|M.abscessus_ATCC_199 RIVGGLLVAAAGAPVLISWRRTRRPEFATPRLALTLRAASFTGHFLAGVL
*:. * * . :. **::: *:: .*:. * :** :* *: *.*:. *
Mb3750|M.bovis_AF2122/97 IVGTAISEVWLSLDAAGQWLFGIYGAAAAIAVLGFFGFYLSFVAELPPPP
Rv3723|M.tuberculosis_H37Rv IVGTAISEVWLSLDAAGQWLFGIYGAAAAIAVLGFFGFYLSFVAELPPPP
MLBr_02337|M.leprae_Br4923 IVSTAIGEIWLSSDTAVQCLFGIYGAAAASAVLGFVAFYLSFVAALPPPS
MMAR_5242|M.marinum_M IIGTAISEIWLSLDSVGQWLFGIYGAAAAIAVLGFFAFYLSFVAELPPPP
MUL_4318|M.ulcerans_Agy99 IIGTAISEIWLSLDSVGQWLFGIYGAAAAIAVLGFFAFYLSFVAELPPPP
MAV_0378|M.avium_104 IIGTAVSEIWLSLDAAGRWLFGIYGAAAAIALLGIFAFYLSFVAELPPPP
Mflv_1279|M.gilvum_PYR-GCK IVGTAISEIWLSVDSAGQWLFGIYGAAAAIGLLGIFAFYLAFVAELPPPP
Mvan_5536|M.vanbaalenii_PYR-1 IVGAAVAEIWISLDSAGQWLFGIYGAAAAVALLGVLAFYLAFVAELPPPP
TH_1678|M.thermoresistible__bu IVGTAVTEIWVSLDDAGQWLFGVYGAAAAIALLGMFAFYLAFVAELPPPP
MSMEG_6288|M.smegmatis_MC2_155 IVGTAIAEIWVSLDSAGSWLFGIYGAAAALALLGAFGFYLAFIAELPPPP
MAB_0283c|M.abscessus_ATCC_199 IVGTAIAEIWLDLDRFGIWEFGGYGAAAAIGILAFAAYHLAFVAERPAPE
*:.:*: *:*:. * ** ****** .:*. .::*:*:* *.*
Mb3750|M.bovis_AF2122/97 PKPLKPKKPKQRRLRRKKT--------AKGDEAEPEAAEEAEN-------
Rv3723|M.tuberculosis_H37Rv PKPLKPKKPKQRRLRRKKT--------AKGDEAEPEAAEEAEN-------
MLBr_02337|M.leprae_Br4923 PKPVKLKKANQRRIRRRKG--------RKDNEAEDEEADAGEHNE-----
MMAR_5242|M.marinum_M PKPIKVKEPKQRRRRKKGD--------EGDDVDETDEADEADEAEDVDEA
MUL_4318|M.ulcerans_Agy99 PKPIKVKEPKQRRRRKKGG--------EGDDVDETDETEDAEDAEDVDEA
MAV_0378|M.avium_104 PKPIKAKKPKKRRLRRKKAG-------EEVETAETAEAEEAEAEEAD---
Mflv_1279|M.gilvum_PYR-GCK PKPLKATKRTGRGRKGDGS---------ED--SADVEGSEGEVLE-----
Mvan_5536|M.vanbaalenii_PYR-1 PKPLKVKKRKSRRGRSDAA---------EDTETADAETADAEVEE-----
TH_1678|M.thermoresistible__bu PKPVKAGKAKKAKKR-----------------TRRGRRPAGDTED-----
MSMEG_6288|M.smegmatis_MC2_155 PKPVKPKVNAVRRNTRAAKDTADADEIDKDAADEDEAGEGEDATERAEDS
MAB_0283c|M.abscessus_ATCC_199 RTPRPAKKKLTRATTENAD----------DSDVDKAIASEPEAR------
.* :
Mb3750|M.bovis_AF2122/97 ---------TELAAQEDEEAVEAPPESIESPGGEPESATREAPAAETAT-
Rv3723|M.tuberculosis_H37Rv ---------TELAAQEDEEAVEAPPESIESPGGEPESATREAPAAETAT-
MLBr_02337|M.leprae_Br4923 ---------AETPAQAEEVTSENPQPAPES-GAQKE--PDELLANKTEE-
MMAR_5242|M.marinum_M GEAEDVDETDEAEETDEAEEADEASDGEESVESEEAEPAEEAEVAEEAEA
MUL_4318|M.ulcerans_Agy99 ------DEADEAEETDEAEEADEASDGEESVESEEAEPTEEAEVAEAAE-
MAV_0378|M.avium_104 ---------ETEAAQTVTAETEAAEAAGETEAAEDTAEAEKPAANEPEAE
Mflv_1279|M.gilvum_PYR-GCK ---------SERTDGVTD---ADVDTGENGVKAEDAPAAVSD--ADDAD-
Mvan_5536|M.vanbaalenii_PYR-1 ---------TETADAETESVTPDADADADADAEEPVPTAEDDPASDTPE-
TH_1678|M.thermoresistible__bu ---------TEPGD---------TEDTAEAPAEDPAES------PPEAE-
MSMEG_6288|M.smegmatis_MC2_155 ADEPSDDTAVEASDEDADQTDDETEDATSENNDEPRAAEPESKAVEPEST
MAB_0283c|M.abscessus_ATCC_199 ----------EPAD----------EPSGDSPDSDEK-------VLEPAR-
. :
Mb3750|M.bovis_AF2122/97 ---AEEPRG---------GLRNRRPTGKTSH-----RRRRTRSGVQVAKV
Rv3723|M.tuberculosis_H37Rv ---AEEPRG---------GLRNRRPTGKTSH-----RRRRTRSGVQVAKV
MLBr_02337|M.leprae_Br4923 ---TDEPRR---------GLHNRRPTGKVSH-----QRRRARSGIAVEN-
MMAR_5242|M.marinum_M DEETAEPEAQGEDATAHGGLRNRRPTGKTSH-----RRRRVRRGVTVEE-
MUL_4318|M.ulcerans_Agy99 --ETAEPEAQGQDATAHGGLRNRRPTGKTSH-----RRRRVRRGVTVEE-
MAV_0378|M.avium_104 TLVAEDSDE------SRAKLRNRRPTGKGTHRM---RRRRTRAGVAVDQT
Mflv_1279|M.gilvum_PYR-GCK -----DADG---------KLRNRRPTGKGTGLG---RRKRTRGGVAVED-
Mvan_5536|M.vanbaalenii_PYR-1 -----SGDG---------KLQNRRPTGKGAVLG---RRKRTRGGVAVED-
TH_1678|M.thermoresistible__bu -----PTDG---------KLRNRRPTGKAR------TRRRLRSDTAADD-
MSMEG_6288|M.smegmatis_MC2_155 AVEAESLDGADTDDSSGGKLRNRRPSNKANKGGSSRFRRRSRGGITVEE-
MAB_0283c|M.abscessus_ATCC_199 ------------------GLRNRR-------------TRRS---------
*:*** :*
Mb3750|M.bovis_AF2122/97 DE---------
Rv3723|M.tuberculosis_H37Rv DE---------
MLBr_02337|M.leprae_Br4923 -----------
MMAR_5242|M.marinum_M -----------
MUL_4318|M.ulcerans_Agy99 -----------
MAV_0378|M.avium_104 AEQSGDDADED
Mflv_1279|M.gilvum_PYR-GCK -----------
Mvan_5536|M.vanbaalenii_PYR-1 -----------
TH_1678|M.thermoresistible__bu -----------
MSMEG_6288|M.smegmatis_MC2_155 -----------
MAB_0283c|M.abscessus_ATCC_199 -----------