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M. bovis AF2122 / 97 Mb3750 (-)

annotation: transmembrane protein
coordinates: 4105996 - 4106760
length: 254

MGRKVAVLWHASFSIGAGVLYFYFVLPRWPELMGDTGHSLGTGLRIATGALVGLAALPVVFTLLRTRKPE
LGTPQLALSMRIWSIMAHVLAGALIVGTAISEVWLSLDAAGQWLFGIYGAAAAIAVLGFFGFYLSFVAEL
PPPPPKPLKPKKPKQRRLRRKKTAKGDEAEPEAAEEAENTELAAQEDEEAVEAPPESIESPGGEPESATR
EAPAAETATAEEPRGGLRNRRPTGKTSHRRRRTRSGVQVAKVDE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3750--100% (254)transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1279-3e-7760.87% (253) hypothetical protein Mflv_1279
M. tuberculosis H37RvRv3723-1e-145100.00% (254) transmembrane protein
M. leprae Br4923MLBr_02337-3e-8664.43% (253) hypothetical protein MLBr_02337
M. abscessus ATCC 19977MAB_0283c-4e-4744.44% (234) hypothetical protein MAB_0283c
M. marinum MMMAR_5242-5e-9767.73% (282) hypothetical protein MMAR_5242
M. avium 104MAV_0378-7e-9466.79% (268) hypothetical protein MAV_0378
M. smegmatis MC2 155MSMEG_6288-2e-7353.26% (291) hypothetical protein MSMEG_6288
M. thermoresistible (build 8)TH_1678-5e-7158.02% (243) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_4318-1e-9870.00% (270) hypothetical protein MUL_4318
M. vanbaalenii PYR-1Mvan_5536-8e-7959.92% (252) hypothetical protein Mvan_5536

CLUSTAL 2.0.9 multiple sequence alignment


Mb3750|M.bovis_AF2122/97            --MGRKVAVL----WHASFSIGAGVLYFYFVLPRWPELMGDTGHSLGTGL
Rv3723|M.tuberculosis_H37Rv         --MGRKVAVL----WHASFSIGAGVLYFYFVLPRWPELMGDTGHSLGTGL
MLBr_02337|M.leprae_Br4923          --MGYKVATL----WHASFSIGAGVLYFYFVLPRWPELIGETTHTLGTTL
MMAR_5242|M.marinum_M               --MGRKVAML----WHASFSIGAGVLYFFFVLPRWPELMGDTAHSLGTGL
MUL_4318|M.ulcerans_Agy99           --MGRKVAML----WHASFSIGAGVLYFFFVVPRWPELMGDTAHSLGTGL
MAV_0378|M.avium_104                --MGRKVAIP----WHASFSIAAGVLYFFFVLPRWPELMGDTTHSLGTAL
Mflv_1279|M.gilvum_PYR-GCK          --MGRTAAVI----WHASFSIAAGVLYFFFVLPRTPELLGDTSHTLGTAL
Mvan_5536|M.vanbaalenii_PYR-1       --MGRTVAVI----WHASFSIAAGVLYFFFVLPRTPELVGDTSPTLGTVL
TH_1678|M.thermoresistible__bu      --MRRTGAVL----WHASFSVIAAVLYFFFVLPRWFELTGQLSETLGTVL
MSMEG_6288|M.smegmatis_MC2_155      --MGRTVAVT----WHVASTLIAAGLFFFFVIPRWPELMGETSPTLGTVL
MAB_0283c|M.abscessus_ATCC_199      MAAGRRTATIVLTSSHAALSLIAGLLFFFFVLPRWPELNGATGHTFGTGM
                                           *       *.: :: *. *:*:**:**  ** *    ::** :

Mb3750|M.bovis_AF2122/97            RIATGALVGLAALPVVFTLLRTRKPELGTPQLALSMRIWSIMAHVLAGAL
Rv3723|M.tuberculosis_H37Rv         RIATGALVGLAALPVVFTLLRTRKPELGTPQLALSMRIWSIMAHVLAGAL
MLBr_02337|M.leprae_Br4923          RIVTGVLFGLAALPVVFTLLRSQTSELGIPQLALSIRTWSIVAHVLSGVL
MMAR_5242|M.marinum_M               RITAGALFGLAALPVVFTLLRTRKPELGTPALALSIRTWSIVAHVLAGVL
MUL_4318|M.ulcerans_Agy99           RITAGALFGLAALPVVFTLLRTRKPELGTPALALSIRTWSIVAHVLAGVL
MAV_0378|M.avium_104                RIVAGVLAALAALPVVFTLLRTRKPELGTPQLALSLRVASIVAHVLAGLL
Mflv_1279|M.gilvum_PYR-GCK          RIVAGALIGLAALPVVFTLLRTRRPEFGTPKLALNLRTASIALHVLAAAL
Mvan_5536|M.vanbaalenii_PYR-1       RVVVGALIGLAALPVVFTLLRTRRPEFGTPQMALNLRTTSIALHVLSGVL
TH_1678|M.thermoresistible__bu      RIVTGVLIGLAALPVVFTLLRTRRPEFGTPQLALTLRTVSIALHVLAGVL
MSMEG_6288|M.smegmatis_MC2_155      RIVTGVLVALTALPVVFTLLRTRRPELGTPELALRLRTTSIVFHVLAGVL
MAB_0283c|M.abscessus_ATCC_199      RIVGGLLVAAAGAPVLISWRRTRRPEFATPRLALTLRAASFTGHFLAGVL
                                    *:. * * . :. **:::  *:: .*:. * :** :*  *:  *.*:. *

Mb3750|M.bovis_AF2122/97            IVGTAISEVWLSLDAAGQWLFGIYGAAAAIAVLGFFGFYLSFVAELPPPP
Rv3723|M.tuberculosis_H37Rv         IVGTAISEVWLSLDAAGQWLFGIYGAAAAIAVLGFFGFYLSFVAELPPPP
MLBr_02337|M.leprae_Br4923          IVSTAIGEIWLSSDTAVQCLFGIYGAAAASAVLGFVAFYLSFVAALPPPS
MMAR_5242|M.marinum_M               IIGTAISEIWLSLDSVGQWLFGIYGAAAAIAVLGFFAFYLSFVAELPPPP
MUL_4318|M.ulcerans_Agy99           IIGTAISEIWLSLDSVGQWLFGIYGAAAAIAVLGFFAFYLSFVAELPPPP
MAV_0378|M.avium_104                IIGTAVSEIWLSLDAAGRWLFGIYGAAAAIALLGIFAFYLSFVAELPPPP
Mflv_1279|M.gilvum_PYR-GCK          IVGTAISEIWLSVDSAGQWLFGIYGAAAAIGLLGIFAFYLAFVAELPPPP
Mvan_5536|M.vanbaalenii_PYR-1       IVGAAVAEIWISLDSAGQWLFGIYGAAAAVALLGVLAFYLAFVAELPPPP
TH_1678|M.thermoresistible__bu      IVGTAVTEIWVSLDDAGQWLFGVYGAAAAIALLGMFAFYLAFVAELPPPP
MSMEG_6288|M.smegmatis_MC2_155      IVGTAIAEIWVSLDSAGSWLFGIYGAAAALALLGAFGFYLAFIAELPPPP
MAB_0283c|M.abscessus_ATCC_199      IVGTAIAEIWLDLDRFGIWEFGGYGAAAAIGILAFAAYHLAFVAERPAPE
                                    *:.:*: *:*:. *      ** ****** .:*.  .::*:*:*  *.* 

Mb3750|M.bovis_AF2122/97            PKPLKPKKPKQRRLRRKKT--------AKGDEAEPEAAEEAEN-------
Rv3723|M.tuberculosis_H37Rv         PKPLKPKKPKQRRLRRKKT--------AKGDEAEPEAAEEAEN-------
MLBr_02337|M.leprae_Br4923          PKPVKLKKANQRRIRRRKG--------RKDNEAEDEEADAGEHNE-----
MMAR_5242|M.marinum_M               PKPIKVKEPKQRRRRKKGD--------EGDDVDETDEADEADEAEDVDEA
MUL_4318|M.ulcerans_Agy99           PKPIKVKEPKQRRRRKKGG--------EGDDVDETDETEDAEDAEDVDEA
MAV_0378|M.avium_104                PKPIKAKKPKKRRLRRKKAG-------EEVETAETAEAEEAEAEEAD---
Mflv_1279|M.gilvum_PYR-GCK          PKPLKATKRTGRGRKGDGS---------ED--SADVEGSEGEVLE-----
Mvan_5536|M.vanbaalenii_PYR-1       PKPLKVKKRKSRRGRSDAA---------EDTETADAETADAEVEE-----
TH_1678|M.thermoresistible__bu      PKPVKAGKAKKAKKR-----------------TRRGRRPAGDTED-----
MSMEG_6288|M.smegmatis_MC2_155      PKPVKPKVNAVRRNTRAAKDTADADEIDKDAADEDEAGEGEDATERAEDS
MAB_0283c|M.abscessus_ATCC_199      RTPRPAKKKLTRATTENAD----------DSDVDKAIASEPEAR------
                                     .*                                      :        

Mb3750|M.bovis_AF2122/97            ---------TELAAQEDEEAVEAPPESIESPGGEPESATREAPAAETAT-
Rv3723|M.tuberculosis_H37Rv         ---------TELAAQEDEEAVEAPPESIESPGGEPESATREAPAAETAT-
MLBr_02337|M.leprae_Br4923          ---------AETPAQAEEVTSENPQPAPES-GAQKE--PDELLANKTEE-
MMAR_5242|M.marinum_M               GEAEDVDETDEAEETDEAEEADEASDGEESVESEEAEPAEEAEVAEEAEA
MUL_4318|M.ulcerans_Agy99           ------DEADEAEETDEAEEADEASDGEESVESEEAEPTEEAEVAEAAE-
MAV_0378|M.avium_104                ---------ETEAAQTVTAETEAAEAAGETEAAEDTAEAEKPAANEPEAE
Mflv_1279|M.gilvum_PYR-GCK          ---------SERTDGVTD---ADVDTGENGVKAEDAPAAVSD--ADDAD-
Mvan_5536|M.vanbaalenii_PYR-1       ---------TETADAETESVTPDADADADADAEEPVPTAEDDPASDTPE-
TH_1678|M.thermoresistible__bu      ---------TEPGD---------TEDTAEAPAEDPAES------PPEAE-
MSMEG_6288|M.smegmatis_MC2_155      ADEPSDDTAVEASDEDADQTDDETEDATSENNDEPRAAEPESKAVEPEST
MAB_0283c|M.abscessus_ATCC_199      ----------EPAD----------EPSGDSPDSDEK-------VLEPAR-
                                                                .    :                

Mb3750|M.bovis_AF2122/97            ---AEEPRG---------GLRNRRPTGKTSH-----RRRRTRSGVQVAKV
Rv3723|M.tuberculosis_H37Rv         ---AEEPRG---------GLRNRRPTGKTSH-----RRRRTRSGVQVAKV
MLBr_02337|M.leprae_Br4923          ---TDEPRR---------GLHNRRPTGKVSH-----QRRRARSGIAVEN-
MMAR_5242|M.marinum_M               DEETAEPEAQGEDATAHGGLRNRRPTGKTSH-----RRRRVRRGVTVEE-
MUL_4318|M.ulcerans_Agy99           --ETAEPEAQGQDATAHGGLRNRRPTGKTSH-----RRRRVRRGVTVEE-
MAV_0378|M.avium_104                TLVAEDSDE------SRAKLRNRRPTGKGTHRM---RRRRTRAGVAVDQT
Mflv_1279|M.gilvum_PYR-GCK          -----DADG---------KLRNRRPTGKGTGLG---RRKRTRGGVAVED-
Mvan_5536|M.vanbaalenii_PYR-1       -----SGDG---------KLQNRRPTGKGAVLG---RRKRTRGGVAVED-
TH_1678|M.thermoresistible__bu      -----PTDG---------KLRNRRPTGKAR------TRRRLRSDTAADD-
MSMEG_6288|M.smegmatis_MC2_155      AVEAESLDGADTDDSSGGKLRNRRPSNKANKGGSSRFRRRSRGGITVEE-
MAB_0283c|M.abscessus_ATCC_199      ------------------GLRNRR-------------TRRS---------
                                                       *:***              :*          

Mb3750|M.bovis_AF2122/97            DE---------
Rv3723|M.tuberculosis_H37Rv         DE---------
MLBr_02337|M.leprae_Br4923          -----------
MMAR_5242|M.marinum_M               -----------
MUL_4318|M.ulcerans_Agy99           -----------
MAV_0378|M.avium_104                AEQSGDDADED
Mflv_1279|M.gilvum_PYR-GCK          -----------
Mvan_5536|M.vanbaalenii_PYR-1       -----------
TH_1678|M.thermoresistible__bu      -----------
MSMEG_6288|M.smegmatis_MC2_155      -----------
MAB_0283c|M.abscessus_ATCC_199      -----------