For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSSSGLTAEMTAESSVDKLPALTPRRPFPARVGPKGNLIYKLITTTDHKLIGIMYVVTCFVFFLIGGIMA LFIRTELAMPGLQFLSNEQYNQLFTMHGTAMLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNALSFWLF LFGALIALAGFITPGGAADFGWTAYSPLSDAIHSPGVGVDLWIFGLGVGGLGTILGAVNMVTTVVCMRAP GMTMFRMPIFTWNILVTSILVLLIFPLLTAALFGLAADRHLGAHVYDPANGGVILWQHLFWYFGHPEVYV IALPFFGIISEVIPVFSRKPIFGYTTLVYATFSIAALSMAVWAHHMFATGAVLLPFFSFMTFLIAVPTGI KFFNWIGTMWKGQLTFETPMLFSVGFILTFLLGGLSGVLLASPPLDFHVTDSYFVVAHFHYVLFGTIVFA TYAGVYFWFPKMTGRLLDERLGKLHFWLTFIGFHLTFLVQHWLGDEGMPRRYADYLPTDGFTTLNGISTI GAFMLGASMLPFVWNVFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPH MRERMRAEAHAGRSHGPDDGDVTRLDEENVRT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1196 | - | - | 100% (592) | cytochrome-c oxidase |
| M. gilvum PYR-GCK | Mflv_4277 | - | 0.0 | 90.89% (571) | cytochrome-c oxidase |
| M. gilvum PYR-GCK | Mflv_2818 | - | 0.0 | 90.37% (571) | cytochrome-c oxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3069c | ctaD | 0.0 | 87.28% (566) | cytochrome C oxidase polypeptide I |
| M. tuberculosis H37Rv | Rv3043c | ctaD | 0.0 | 87.28% (566) | cytochrome C oxidase polypeptide I |
| M. leprae Br4923 | MLBr_01728 | - | 0.0 | 86.32% (570) | cytochrome C oxidase, polypeptide I |
| M. abscessus ATCC 19977 | MAB_3389c | - | 0.0 | 86.22% (566) | cytochrome c oxidase polypeptide I |
| M. marinum M | MMAR_1651 | ctaD | 0.0 | 88.16% (566) | cytochrome C oxidase polypeptide I CtaD |
| M. avium 104 | MAV_3908 | ctaD | 0.0 | 87.66% (543) | cytochrome c oxidase, subunit I |
| M. smegmatis MC2 155 | MSMEG_4437 | ctaD | 0.0 | 86.13% (555) | cytochrome c oxidase, subunit I |
| M. thermoresistible (build 8) | TH_1815 | ctaD | 1e-171 | 85.27% (319) | PROBABLE CYTOCHROME C OXIDASE POLYPEPTIDE I CTAD (CYTOCHROME |
| M. ulcerans Agy99 | MUL_1887 | ctaD | 0.0 | 87.81% (566) | cytochrome C oxidase polypeptide I CtaD |
| M. vanbaalenii PYR-1 | Mvan_5610 | - | 0.0 | 94.18% (584) | cytochrome-c oxidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1196|M.gilvum_PYR-GCK MSSSGLTAEMTAESSVDKLPALTPRRPFPARVGPKGNLIYKLITTTDHKL
Mvan_5610|M.vanbaalenii_PYR-1 ---------MTAESTVEKPTTLVPKRPFPARLGPKGNLIYKLITTTDHKL
MAV_3908|M.avium_104 -------------------------------------------------M
Mb3069c|M.bovis_AF2122/97 ---------MTAEAPP--LGELEAIRPYPARTGPKGSLVYKLITTTDHKM
Rv3043c|M.tuberculosis_H37Rv ---------MTAEAPP--LGELEAIRPYPARTGPKGSLVYKLITTTDHKM
MLBr_01728|M.leprae_Br4923 ---------MTAEALS--SGELKAIRPYPARTGPKGNLVYKLITTTDHKM
MMAR_1651|M.marinum_M ---------MTAEAPP--LGELEAIRPYPARTGPKGNLVYKLLTTTDHKL
MUL_1887|M.ulcerans_Agy99 ---------MTAEAPP--LGELEAIRPYPARTGPKGNLVYKLLTTTDHKL
MAB_3389c|M.abscessus_ATCC_199 ---------MTAEAPP--IGGLQASRPFPPRMGARGTLIYRLITTTDHKL
MSMEG_4437|M.smegmatis_MC2_155 ---------MTTHAPS--AGELLARRPFPQRLGPRWTLLYKLVTTTDHKL
TH_1815|M.thermoresistible__bu --------------------------------------------------
Mflv_1196|M.gilvum_PYR-GCK IGIMYVVTCFVFFLIGGIMALFIRTELAMPGLQFLSNEQYNQLFTMHGTA
Mvan_5610|M.vanbaalenii_PYR-1 IGIMYVVTCFVFFLIGGIMALFIRTELAVPGLQFLSNEQYNQLFTMHGTA
MAV_3908|M.avium_104 IGIMYTVTCFAFFFIGGLMALLMRTELAAPGLQFLSNEQFNQLFTMHGTI
Mb3069c|M.bovis_AF2122/97 IGIMYCVACISFFFIGGLLALLMRTELAAPGLQFLSNEQFNQLFTMHGTI
Rv3043c|M.tuberculosis_H37Rv IGIMYCVACISFFFIGGLLALLMRTELAAPGLQFLSNEQFNQLFTMHGTI
MLBr_01728|M.leprae_Br4923 IGIMYCVACFIFFFVGGLLALLMRTELAAPGLQFLSNEQFNQLFTMHGTI
MMAR_1651|M.marinum_M IGIMYVVTCFIFFLIGGLLALLMRTELATPGLQFLSNEQFNQLFTMHGTV
MUL_1887|M.ulcerans_Agy99 IGIMYVVTCFIFFLIGGLLALLMRTELATPGLQFLSNEQFNQLFTMHGTV
MAB_3389c|M.abscessus_ATCC_199 IGIMYLVACFAFFLIGGLMALFMRAELAVPGLQFLSNEQFNQLFTMHGTV
MSMEG_4437|M.smegmatis_MC2_155 IGMMYVVACFIFFFIGGLMALLLRTELAVPGLQFLSNEQYNQLFTMHGTV
TH_1815|M.thermoresistible__bu --------------------------------------------------
Mflv_1196|M.gilvum_PYR-GCK MLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNALSFWLFLFGALIALAG
Mvan_5610|M.vanbaalenii_PYR-1 MLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGALIALSG
MAV_3908|M.avium_104 MLLLYATPVVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGGLIAASG
Mb3069c|M.bovis_AF2122/97 MLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFVFGATIGAAG
Rv3043c|M.tuberculosis_H37Rv MLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFVFGATIGAAG
MLBr_01728|M.leprae_Br4923 MLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGAAIGMAG
MMAR_1651|M.marinum_M MLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGATLGMAG
MUL_1887|M.ulcerans_Agy99 MLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGATLGMAG
MAB_3389c|M.abscessus_ATCC_199 MLLFYATPIVFGFANVVLPLQIGAPDVAFPRLNAFSFWLFLFGALIGIAG
MSMEG_4437|M.smegmatis_MC2_155 MLLFYATPIVFGFANLVVPLQIGAPDVAFPRLNALSFWLFLFGASIALGG
TH_1815|M.thermoresistible__bu ------------------------------------------------VG
*
Mflv_1196|M.gilvum_PYR-GCK FITPGGAADFGWTAYSPLSDAIHSPGVGVDLWIFGLGVGGLGTILGAVNM
Mvan_5610|M.vanbaalenii_PYR-1 FITPGGAADFGWTAYTPLSDAMYSPGAGGDLWIFGLGVGGLGTILGAVNM
MAV_3908|M.avium_104 FIVPGGAADFGWTAYTPLSDAVHSPGAGGDLWITGLIVAGLGTILGAVNM
Mb3069c|M.bovis_AF2122/97 FITPGGAADFGWTAYTPLTDAIHSPGAGGDLWIMGLIVAGLGTILGAVNM
Rv3043c|M.tuberculosis_H37Rv FITPGGAADFGWTAYTPLTDAIHSPGAGGDLWIMGLIVAGLGTILGAVNM
MLBr_01728|M.leprae_Br4923 FITPGGAADFGWTAYTPLTDAIHSPGVGGDLWIMGLIVAGLGTILGAVNM
MMAR_1651|M.marinum_M FITPGGAADFGWTAYTPLTDAIHSPGVGGDLWIMGIAVGGLGTILGAVNM
MUL_1887|M.ulcerans_Agy99 FITPGGAADFGWTAYTPLTDAIHSPGVGGDLWIMGIAVGGLGTILGAVNM
MAB_3389c|M.abscessus_ATCC_199 FITPGGAADFGWTAYTPLTDAIHSPGAGADLWIMGLAVGGLGTILGAVNM
MSMEG_4437|M.smegmatis_MC2_155 FLAPGGPADFGWTAYTPLSNAMHSPGAGGDLWIFGLIVGGLGTILGAVNM
TH_1815|M.thermoresistible__bu RIR----ADLCWDR------AMRSR---------------------YVPY
: **: * *: * *
Mflv_1196|M.gilvum_PYR-GCK VTTVVCMRAPGMTMFRMPIFTWNILVTSILVLLIFPLLTAALFGLAADRH
Mvan_5610|M.vanbaalenii_PYR-1 ITTVVCMRAPGMTMFRMPIFTWNILVTSILVLLIFPLLTAALFGLAADRH
MAV_3908|M.avium_104 ITTVVCMRAPGMTMFRMPIFTWNILVTSILILIAFPILTAALFGLAADRH
Mb3069c|M.bovis_AF2122/97 ITTVVCMRAPGMTMFRMPIFTWNIMVTSILILIAFPLLTAALFGLAADRH
Rv3043c|M.tuberculosis_H37Rv ITTVVCMRAPGMTMFRMPIFTWNIMVTSILILIAFPLLTAALFGLAADRH
MLBr_01728|M.leprae_Br4923 ITTVVCLRAPGMTMFRMPIFTWNILVTSILVLIAFPLLTAALFGLAADRH
MMAR_1651|M.marinum_M ITTVVCMRAPGMTMFRMPIFTWNILVTSILVLIAFPLLTAALFGLAADRH
MUL_1887|M.ulcerans_Agy99 ITTVVCMRAPGMTMFRMSIFTWNILVTSILVLIAFPLLTAALFGLAADRH
MAB_3389c|M.abscessus_ATCC_199 ITTVVCMRAPGMTMFRMPIFTWNILVTSVLVLLAFPLLTAALFGLAADRH
MSMEG_4437|M.smegmatis_MC2_155 ITTVVCMRAPGMIMFRMPIFTWNILVTSVIVLVAFPLLTSALFGLAADRN
TH_1815|M.thermoresistible__bu ATTPARLLAQLLSDIVIALW------IAVWVLVGMAVHTA----VSTIAE
** . : * : : :.:: :: :*: :.: *: ::: .
Mflv_1196|M.gilvum_PYR-GCK LGAHVYDPANGGVILWQHLFWYFGHPEVYVIALPFFGIISEVIPVFSRKP
Mvan_5610|M.vanbaalenii_PYR-1 LGAHVYDPANGGVLLWQHLFWYFGHPEVYVIALPFFGIISEVIPVFSRKP
MAV_3908|M.avium_104 LGAHVYDAANGGVLLWQHLFWFFGHPEVYIIALPFFGIITEIIPVFARKP
Mb3069c|M.bovis_AF2122/97 LGAHIYDAANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKP
Rv3043c|M.tuberculosis_H37Rv LGAHIYDAANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKP
MLBr_01728|M.leprae_Br4923 LGAHIYDAANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKP
MMAR_1651|M.marinum_M LGAHIYDPANGGVLLWQHLFWFFGHPEVYILALPFFGVVSEIFPVFSRKP
MUL_1887|M.ulcerans_Agy99 LGAHIYDPANGGVLLWQHLFWFFGHPEVYILALPFFGVVSEIFPVFSRKP
MAB_3389c|M.abscessus_ATCC_199 LGAHVFDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKP
MSMEG_4437|M.smegmatis_MC2_155 LGAHVFDPANGGTMLWEHLFWFFGHPEVYIIALPFFGIVTEIFPVFSRKP
TH_1815|M.thermoresistible__bu VGRNVHTGATG-------------VSEXXXVALPFFGIVTEIFPVFSRKP
:* ::. *.* .* :******:::*::***:***
Mflv_1196|M.gilvum_PYR-GCK IFGYTTLVYATFSIAALSMAVWAHHMFATGAVLLPFFSFMTFLIAVPTGI
Mvan_5610|M.vanbaalenii_PYR-1 IFGYTTLIYATFSIGALSMAVWAHHMFATGAVLYPFFSFMTFLIAVPTGI
MAV_3908|M.avium_104 VFGYTTLVYATLSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGI
Mb3069c|M.bovis_AF2122/97 IFGYTTLVYATLSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGI
Rv3043c|M.tuberculosis_H37Rv IFGYTTLVYATLSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGI
MLBr_01728|M.leprae_Br4923 IFGYTTLVYATLSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGI
MMAR_1651|M.marinum_M IFGYTTLVYATLSIAALSVAVWAHHMFATGAVLLPFFSFMTFLIAVPTGI
MUL_1887|M.ulcerans_Agy99 IFGYTTLVYATLSIAALSVAVWAHHMFATGAVLLPFFSFMTFLIAVPTGI
MAB_3389c|M.abscessus_ATCC_199 IFGYTTLIYATLGIAALSIAVWAHHMYATGAVLLPFFSFMTFLIAVPTGI
MSMEG_4437|M.smegmatis_MC2_155 VFGYTTLVYATISIGALSIAVWAHHLYATGAVLLPFFSFMTFMIAVPTGI
TH_1815|M.thermoresistible__bu VFGYTALVYATVGIGALSMAVWAHHMFATGAVLLPFFAFTTYLIAVPTGI
:****:*:***..*.***:******::****** ***:* *::*******
Mflv_1196|M.gilvum_PYR-GCK KFFNWIGTMWKGQLTFETPMLFSVGFILTFLLGGLSGVLLASPPLDFHVT
Mvan_5610|M.vanbaalenii_PYR-1 KFFNWLGTMWKGQLTFETPMLFSVGFIATFLLGGLSGVLLASPPLDFHVH
MAV_3908|M.avium_104 KFFNWIGTMWKGQLTFETPMLFCVGFLLTFLLGGLTGVMLASPPLDFHVT
Mb3069c|M.bovis_AF2122/97 KFFNWIGTMWKGQLTFETPMLFSVGFMVTFLLGGLTGVLLASPPLDFHVT
Rv3043c|M.tuberculosis_H37Rv KFFNWIGTMWKGQLTFETPMLFSVGFMVTFLLGGLTGVLLASPPLDFHVT
MLBr_01728|M.leprae_Br4923 KFFNWVGTMWKGQLTFETPMLFSVGFAVTFLLGGLTGVLLASPPLDFHVT
MMAR_1651|M.marinum_M KFFNWVGTMWKGQLTFETPMLFSVGFAVTFLLGGLSGVLLASPPLDFHVT
MUL_1887|M.ulcerans_Agy99 KFFNWVGTMWKGQLTFETPMLFSVGFAVTFLLGGLSGVLLASPPLNFHVT
MAB_3389c|M.abscessus_ATCC_199 KFFNWIGTMWKGQLTFETPMIFSVGFLVTFLFGGLTGVLLAMPPVDFHVT
MSMEG_4437|M.smegmatis_MC2_155 KFVNWIGTMWKGQLTFETPMLFSVGFLVTFLLGGLTGVILASPPLDFHVT
TH_1815|M.thermoresistible__bu KFFNWIGTMWKGQLTFESPMLFSVGFILTFLIGGLSGVMLASPPLDFHVT
**.**:***********:**:*.*** ***:***:**:** **::***
Mflv_1196|M.gilvum_PYR-GCK DSYFVVAHFHYVLFGTIVFATYAGVYFWFPKMTGRLLDERLGKLHFWLTF
Mvan_5610|M.vanbaalenii_PYR-1 DSYFVVAHFHYVLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTF
MAV_3908|M.avium_104 DTYFVVAHFHYVLFGTIVFATFAGVYFWFPKMTGRLLDERLGKLHFWLTF
Mb3069c|M.bovis_AF2122/97 DSYFVVAHFHYVLFGTIVFATFAGIYFWFPKMTGRLLDERLGKLHFWLTF
Rv3043c|M.tuberculosis_H37Rv DSYFVVAHFHYVLFGTIVFATFAGIYFWFPKMTGRLLDERLGKLHFWLTF
MLBr_01728|M.leprae_Br4923 DSYFVVAHFHYVLFGTIVFSTFAGIYFWFPKMTGRLLDEQLGKLHFWLTF
MMAR_1651|M.marinum_M DSYFVVAHFHYVLFGTIVFSTFAGIYFWFPKMTGRLLDERLGKLHFWLTF
MUL_1887|M.ulcerans_Agy99 DSYFVVAHFHYVLFGTIVFSTFAGIYFWFPKMTGRLLDERLGKLHFWLTF
MAB_3389c|M.abscessus_ATCC_199 DSYFVIAHFHYVLFGTIVFATYAGIYFWFPKMTGRLLDERLGKFHFWLTF
MSMEG_4437|M.smegmatis_MC2_155 DSYFVVAHFHYVLFGTIVFATYAGVYFWFPKMTGRLLDDRLGKLHFWLTL
TH_1815|M.thermoresistible__bu DTYFLVAHFHYVLFGTIVFATFAGVYFWFPKMTGRMLDERLAKLHFWLTF
*:**::*************:*:**:**********:**::*.*:*****:
Mflv_1196|M.gilvum_PYR-GCK IGFHLTFLVQHWLGDEGMPRRYADYLPTDGFTTLNGISTIGAFMLGASML
Mvan_5610|M.vanbaalenii_PYR-1 IGFHTTFLVQHWLGDEGMPRRYADYLPTDGFTTLNVISTIGAFILGASML
MAV_3908|M.avium_104 IGFHTTFLVQHWLGDLGMPRRYADYLPSDGFQPYNVASTVGAFILGASMF
Mb3069c|M.bovis_AF2122/97 IGFHTTFLVQHWLGDEGMPRRYADYLPTDGFQGLNVVSTIGAFILGASMF
Rv3043c|M.tuberculosis_H37Rv IGFHTTFLVQHWLGDEGMPRRYADYLPTDGFQGLNVVSTIGAFILGASMF
MLBr_01728|M.leprae_Br4923 IGFHTTFLVQHWLGDMGMPRRYADYLPTDGFQGLNVVSTIGSFILGASMF
MMAR_1651|M.marinum_M IGFHTTFLVQHWLGDEGMPRRYADYLPTDGFQGLNIVSTIGAFILGVAMI
MUL_1887|M.ulcerans_Agy99 IGFHTTFLVQHWLGDEGMPRRYADYLPTDGFQGLNIVSTIGAFILGVAMF
MAB_3389c|M.abscessus_ATCC_199 IGFHSTFLVQHWLGNQGMPRRYADYLPTDGFTFLNSFSTVGAFILGASTL
MSMEG_4437|M.smegmatis_MC2_155 IGFHTTFLVHHWLGAEGMPRRYADYLPTDGFTTLNIVSTIGSFILGVSML
TH_1815|M.thermoresistible__bu IGFHTTFLVQHWLGNEGMPRRYADYLPTDGFTELNIVSSVGAFILGASML
**** ****:**** ***********:*** * *::*:*:**.: :
Mflv_1196|M.gilvum_PYR-GCK PFVWNVFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSE
Mvan_5610|M.vanbaalenii_PYR-1 PFVWNVFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSE
MAV_3908|M.avium_104 PFVWNVFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSE
Mb3069c|M.bovis_AF2122/97 PFVWNVFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSE
Rv3043c|M.tuberculosis_H37Rv PFVWNVFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSE
MLBr_01728|M.leprae_Br4923 PFVWNVFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSE
MMAR_1651|M.marinum_M PFVWNVFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSE
MUL_1887|M.ulcerans_Agy99 PFVWNVFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSE
MAB_3389c|M.abscessus_ATCC_199 PFLWNVFKSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPRIRSE
MSMEG_4437|M.smegmatis_MC2_155 PFVWNVFKSWRYGEPVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSE
TH_1815|M.thermoresistible__bu PFIWNVFKSWRYGDPVTVDDPWGYGNSLEWATTCPPPRHNFYELPRIRSE
**:******:***: *****************:******** ********
Mflv_1196|M.gilvum_PYR-GCK RPAFELHYPHMRERMRAEAHAGRSHG-PDDGDVTRLDEENVRT-
Mvan_5610|M.vanbaalenii_PYR-1 RPAFELHYPHMVERMRAEAHAGRKHGGPAGGDVTRLDDENVRT-
MAV_3908|M.avium_104 RPAFELHYPHMVERLRAEAHVGRAHG-PADKDVTRLDDVQVRS-
Mb3069c|M.bovis_AF2122/97 RPAFELHYPHMVERLRAEAHVGRHHDEPAMVTSS----------
Rv3043c|M.tuberculosis_H37Rv RPAFELHYPHMVERLRAEAHVGRHHDEPAMVTSS----------
MLBr_01728|M.leprae_Br4923 RPAFELHYPHMVERLRDEAYVGRRHAEELVEVSLH---------
MMAR_1651|M.marinum_M RPAFELHYPHMVERLRAEAHVGRHHDELAKATSS----------
MUL_1887|M.ulcerans_Agy99 RPAFELHYPHMVERLRAEAHVGRHHDELAKATSS----------
MAB_3389c|M.abscessus_ATCC_199 RPAFELHYPHMSERMRAEAHVGGGH-------------------
MSMEG_4437|M.smegmatis_MC2_155 RPAFELHYPHMIERLRAESHPGRTQGGPGAVTLPQPQARSHPVE
TH_1815|M.thermoresistible__bu RPAFELHYPHMIERMRAESHIGRSHG-PADGDVTRMEDTNVRT-
*********** **:* *:: * :