For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_1030 (-)

SALNPDCLALQERLWAAVMDGDEYTASTVVFGALDAGLDPEDVLLDVIAVVQRRVGTEWAANRITVAQEH
AATAINDRVIAALAHHPKACRRPDAGRVTVACVDGEWHALPARLLAEVLRLRGWQVDFLGAQVPTPHLIA
HVHQHGPVAVALSCSIPTRLPTAHAAITACQAAGVPVLAGGAAFGFDGRFARLLGADAWASDARTAADLL
RGGVRPAQSTATHQPIDDLPHLADQEYTMVRSTATTLVQTTVEELEDRYPAMRDYNPAQRERTAEDIAHI
VAFLSTALYTDDDDLFTEFVCWTAEILVARAVPAESLYPALDSLSGQLREFPRAQRLLTAAHAALHQSTT
TNPPLFA*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_1030	-	-	100% (358)	cobalamin B12-binding domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	-	-	-	-	-
M. avium 104	-	-	-	-	-
M. smegmatis MC2 155	MSMEG_6542	-	1e-129	67.75% (338)	B12-binding domain-containing protein
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_5806	-	1e-152	76.59% (346)	cobalamin B12-binding domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1030|M.gilvum_PYR-GCK          ---MSALNPD-------CLALQERLWAAVMDGDEYTASTVVFGALDAGLD
Mvan_5806|M.vanbaalenii_PYR-1       ------MSVD-------ASRARERLWAAVLEADEFAAATTVFGAVDGGMP
MSMEG_6542|M.smegmatis_MC2_155      MSHGDGAAADPVTDPAVVESLRDRLWDAVIEADEDAAVDVVFGALEDGVP
                                             *           ::*** **::.** :*  .****:: *: 

Mflv_1030|M.gilvum_PYR-GCK          PEDVLLDVIAVVQRRVGTEWAANRITVAQEHAATAINDRVIAALAHHPKA
Mvan_5806|M.vanbaalenii_PYR-1       PEDVLLDVIASVQRRVGSEWAANRITVAQEHAATAINDRVIAALAHHPAC
MSMEG_6542|M.smegmatis_MC2_155      GEDLLLDVIAAVQRRVGVEWADNRLTVAAEHAATAINDRVIAALVRHPAV
                                     **:****** ****** *** **:*** ***************.:**  

Mflv_1030|M.gilvum_PYR-GCK          CRRPDAGRVTVACVDGEWHALPARLLAEVLRLRGWQVDFLGAQVPTPHLI
Mvan_5806|M.vanbaalenii_PYR-1       SRADGAGRVTVACVDGEWHALPARLLAEVLRLRGWHVDFLGAQVPTPHLI
MSMEG_6542|M.smegmatis_MC2_155      ARQTTTGRVAVACADGEWHALPARLLAEVLRLRGWRVDFLGAQVPTPHLI
                                    .*   :***:***.*********************:**************

Mflv_1030|M.gilvum_PYR-GCK          AHVHQHGPVAVALSCSIPTRLPTAHAAITACQAAGVPVLAGGAAFGFDGR
Mvan_5806|M.vanbaalenii_PYR-1       AHLHQHGPEAVALSCMIPTRLPTAHAAITACQAAGTAVLAGGAAFGADGR
MSMEG_6542|M.smegmatis_MC2_155      AHLHQHGPDAVALSCSISTRLPTAHAAITACQGAGVPVLVGGAGFGPDGR
                                    **:***** ****** *.**************.**..**.***.** ***

Mflv_1030|M.gilvum_PYR-GCK          FARLLGADAWASDARTAADLLRGGVRPAQSTATHQPIDDLPHLADQEYTM
Mvan_5806|M.vanbaalenii_PYR-1       FARQLGADAWAPDARAAAELLGRGLRPARTSPTHQPIDDLPHLADQEYTM
MSMEG_6542|M.smegmatis_MC2_155      YARLLGADAWAPDARAAAAQLADGLALTRRAPRDHLFDELPHLADQEYTM
                                    :** *******.***:**  *  *:  :: :. .: :*:***********

Mflv_1030|M.gilvum_PYR-GCK          VRSTATTLVQTTVEELEDRYPAMRDYNPAQRERTAEDIAHIVAFLSTALY
Mvan_5806|M.vanbaalenii_PYR-1       VKSAGAQLIQTTLWELEQRFPAMRGYTEMQRQHTIEDLAHIVDFLTTALY
MSMEG_6542|M.smegmatis_MC2_155      VSTTAGRLVRDTVSGLEKRVPAMASYSQLQRQHTSTDVAHIVDFLATALY
                                    * ::.  *:: *:  **.* *** .*.  **::*  *:**** **:****

Mflv_1030|M.gilvum_PYR-GCK          TDDDDLFTEFVCWTAEILVARAVPAESLYPALDSLSGQLREFPRAQRLLT
Mvan_5806|M.vanbaalenii_PYR-1       VDDDDLFTGFITWTADILAARDVPAASLIPALESLAGQLPEFPRTQRLLK
MSMEG_6542|M.smegmatis_MC2_155      VDDPELFTGFIAWTAEVLDARGVPVDSLQPTLELLGAQLQDFPRTQRMLS
                                    .** :*** *: ***::* ** **. ** *:*: *..** :***:**:*.

Mflv_1030|M.gilvum_PYR-GCK          AAHAALHQSTTTNPPLFA
Mvan_5806|M.vanbaalenii_PYR-1       AAHAAFPPTPTT-PSLPV
MSMEG_6542|M.smegmatis_MC2_155      AARDMLHATYARRNG---
                                    **:  :  : :