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NEPDSNKLLQALDKSIETAGKLARQRVEALRSKHPQLSDEQLLKKVDTTFTSAVTTTGAATGAMAAAPGV GTAAGLVAAAGDTSWFLAAAAAYVLSAAELRGVKVEDFEHQRALVLMVLAGGGGSTFFTNAASRTGPHLG KIVTNAVPLSTIRSINKVLGAHFVTKYGTKRGIIAIGKVAPFGVGFAIGAGGNLVMARGVIKTARIMFDS ADALNRSDTGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0802 | - | - | 100% (222) | hypothetical protein Mflv_0802 |
| M. gilvum PYR-GCK | Mflv_2219 | - | 5e-30 | 34.62% (208) | hypothetical protein Mflv_2219 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1281c | - | 9e-29 | 35.55% (211) | hypothetical protein Mb1281c |
| M. tuberculosis H37Rv | Rv1249c | - | 3e-29 | 36.02% (211) | hypothetical protein Rv1249c |
| M. leprae Br4923 | MLBr_01096 | - | 8e-28 | 32.39% (213) | hypothetical protein MLBr_01096 |
| M. abscessus ATCC 19977 | MAB_1394c | - | 6e-29 | 34.93% (209) | hypothetical protein MAB_1394c |
| M. marinum M | MMAR_4193 | - | 3e-30 | 35.10% (208) | hypothetical protein MMAR_4193 |
| M. avium 104 | MAV_1386 | - | 2e-27 | 33.65% (208) | hypothetical protein MAV_1386 |
| M. smegmatis MC2 155 | MSMEG_5048 | - | 4e-29 | 34.80% (204) | hypothetical protein MSMEG_5048 |
| M. thermoresistible (build 8) | TH_1000 | - | 2e-27 | 41.61% (161) | POSSIBLE MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4499 | - | 3e-28 | 34.48% (203) | hypothetical protein MUL_4499 |
| M. vanbaalenii PYR-1 | Mvan_4476 | - | 1e-30 | 35.10% (208) | hypothetical protein Mvan_4476 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1281c|M.bovis_AF2122/97 --MSARRIRSWKRFDNRSANAAEPDPQLAGTGGRPKVSTRALAQVIERSS
Rv1249c|M.tuberculosis_H37Rv --MSARRIRSWKRFDNRSANAAEPDPQLAGTGGRPKVSTRALAQVIERSS
MMAR_4193|M.marinum_M --MSARRTR-----------QSEPAAQPTGIMGRPKASTRALAQVIERSS
MUL_4499|M.ulcerans_Agy99 --MSARRTR-----------QSEPAAQPTGIMGRPKASTRALAQVIERSS
MAV_1386|M.avium_104 --MRARRNRFPNR------FFSTSSAAARTDSGRPKVSARALAQVIERSS
MLBr_01096|M.leprae_Br4923 -----------------------------------------MAQVIERSV
MSMEG_5048|M.smegmatis_MC2_155 --MVFGRSKSKN--------LPATVEGANGLSDDPGTAAKVLSHIIESST
Mvan_4476|M.vanbaalenii_PYR-1 ---MFARSRGKG--------QPPAVVDE-----DPGAAAKVLSQIIERGA
TH_1000|M.thermoresistible__bu --------------------------------------------------
MAB_1394c|M.abscessus_ATCC_199 MPMSTRITEP----------QRQLALGGKSKESKPGASGKLLSLVLDQST
Mflv_0802|M.gilvum_PYR-GCK ---------------------------------MNEPDSNKLLQALDKSI
Mb1281c|M.bovis_AF2122/97 RIQGPAAQAYVARLRRAHPGASPAKIVAKLEKRFLSVVTASGAAVGTAAT
Rv1249c|M.tuberculosis_H37Rv RIQGPAAQAYVARLRRAHPGASPAKIVAKLEKRFLSVVTASGAAVGAAAT
MMAR_4193|M.marinum_M HIQSPAAEAYVARLRRAHPAASPAEIVSKIEKRFLAVVTASGAAVGAAAT
MUL_4499|M.ulcerans_Agy99 HIQSPAAEAYMARLRRAHPAASPAEIVSKIEKRFLAVVTASGAAVGAAAT
MAV_1386|M.avium_104 RIQGPAAEAYVTRLRNAHPDAGPAEILAKLQKRYLAIVTAGGVAVGAAAT
MLBr_01096|M.leprae_Br4923 WIQGPAAEAYVARLRRTHPSASPTEIVAKLEKHYLAALTASGAVVGSVAT
MSMEG_5048|M.smegmatis_MC2_155 RVQAPAVRAYVERLRSQQPDATPAQIVSRLEKHYLAAVMASGAAVGSAAA
Mvan_4476|M.vanbaalenii_PYR-1 RVQGPAVKAYVERLRDNNPGATPAEIIDKLDKKYLAAVMASGAAVGSTAA
TH_1000|M.thermoresistible__bu -------------------------------------VVASGAAVGSTAA
MAB_1394c|M.abscessus_ATCC_199 KVQEPAVRAYVQKLRATHPTATPADVVAMLEKRYLATVMGSGAAVGAAAA
Mflv_0802|M.gilvum_PYR-GCK ETAGKLARQRVEALRSKHPQLSDEQLLKKVDTTFTSAVTTTGAATGAMAA
: *...*: *:
Mb1281c|M.bovis_AF2122/97 LPGIGTLAAWFAAAGEVVVFLEATALFVLALASVHAIPLDHRERRRALVL
Rv1249c|M.tuberculosis_H37Rv LPGIGTLAAWFAAAGEVVVFLEATALFVLALASVHAIPLDHRERRRALVL
MMAR_4193|M.marinum_M LPGIGTLAALSAAAGETAVFLEATALLVLALASVYDIPLDHRERRRALVL
MUL_4499|M.ulcerans_Agy99 LPGIGTLAALSAAAGETAVFLEATALLVLALASVYDHPLDHRERRGALVL
MAV_1386|M.avium_104 IPGIGTLSALSAAAAETVTFLEATAFFVLAAAVVYDIPADHRERRRALVL
MLBr_01096|M.leprae_Br4923 LPGIGTLAAVSANAGETVFFLEATAVFVLTIASVYGIPANHRERRRALVL
MSMEG_5048|M.smegmatis_MC2_155 FPGIGTLAALSAVAGETVVFLEATSVFVLAVAEVHGIPADHRERRRALVL
Mvan_4476|M.vanbaalenii_PYR-1 YPGIGTLVAMSAVAGETVVFLEATALYVLAVAEVHGIPAEHRERRRALVL
TH_1000|M.thermoresistible__bu VPGVGTLAALSAVTGETAVFLEATAVFVLAVAEVHGIPLEERERRRALVL
MAB_1394c|M.abscessus_ATCC_199 FPGVGTLAALSATAGEAVLFLEATSLFTLALAAVHDIELAKIEHRHTLVL
Mflv_0802|M.gilvum_PYR-GCK APGVGTAAGLVAAAGDTSWFLAAAAAYVLSAAELRGVKVEDFEHQRALVL
**:** . * :.:. ** *:: .*: * : . *:: :***
Mb1281c|M.bovis_AF2122/97 AVLVGDN-TTAVADLLG-PGRTSG-GWVSETMASLPLPAISSLNSRMLKY
Rv1249c|M.tuberculosis_H37Rv AVLVGDN-TTAVADLLG-PGRTSG-GWVSETMASLPLPAISSLNSRMLKY
MMAR_4193|M.marinum_M AVLVGDNSKNAVAEVIG-SGRTSG-VWVSESMASLPLPAISKLNTRMFKY
MUL_4499|M.ulcerans_Agy99 AVLVGDNSKNAVAEVIG-SGRTSG-VWVSESMASLPLPAISKLNTRMFKY
MAV_1386|M.avium_104 AVLVGDNSERAVAQLIG-PGRTQG-GWVSESLAAVPLSSMSRLNSRLLKS
MLBr_01096|M.leprae_Br4923 AVLAGDDTRLTIGELIG-PGRTNG-GWLLEGMASLPLSTWSQLHTRMLRY
MSMEG_5048|M.smegmatis_MC2_155 SVLVGEDSKRALADLLG-TGRTSG-AWLSDGAATLPLPAVSQLNSRLVRY
Mvan_4476|M.vanbaalenii_PYR-1 SVLVGEDSKRAVADLLG-SGRTSG-AWVSDGAATLPLPALSQLNSRLLRY
TH_1000|M.thermoresistible__bu AVLVGDEGKGAVRDLLG-RGRTSG-AWISEGAATLPLPTVSQLNSRLLRY
MAB_1394c|M.abscessus_ATCC_199 AVLLGEDGETTVSDVLG-KERTVGGGWLAEATSTLPVPALSHLNATLLKR
Mflv_0802|M.gilvum_PYR-GCK MVLAGGGGSTFFTNAASRTGPHLG----KIVTNAVPLSTIRSINKVLGAH
** * . : . * ::*:.: :: :
Mb1281c|M.bovis_AF2122/97 VVKRFALKRGALMFGKLVPMGIGAIIGAIGNRLVGKKLVRNARSAFGTPP
Rv1249c|M.tuberculosis_H37Rv VVKRFALKRGALMFGKLVPMGIGAIIGAIGNRLVGKKLVRNARSAFGTPP
MMAR_4193|M.marinum_M FVKRFALKRGVLLFGKLLPAGIGAIIGAIGNRLVGRKLVRNARSAFGAPP
MUL_4499|M.ulcerans_Agy99 FVKRFALKRGVLLFGKLLPAGIGAIIGAIGNRLVGRKLVRNARSAFGAPP
MAV_1386|M.avium_104 WVRRYTLRRGALLFGKLLPVGIGVVVGAVGNYLAGKKIIRNANRAFGAPP
MLBr_01096|M.leprae_Br4923 AAKRCTVRRGALMFGKILPIGIGAAVGGAGNRVVGKKIISNTRNAFGTAP
MSMEG_5048|M.smegmatis_MC2_155 FVKRYTLKRGAMAFGKLLPVGIGALIGGVGNRMMGKKIVANAAKAFGAPP
Mvan_4476|M.vanbaalenii_PYR-1 FVKRYTLKRGALAFGKMLPVGIGAVVGGVGNRFMGKKIIANAHNAFGAAP
TH_1000|M.thermoresistible__bu FVKRYTLKRGALAFGKALPVGVGAVVGGVGNRMMGKKIIGNARTAFGAAP
MAB_1394c|M.abscessus_ATCC_199 FTKKFAVKRGAMAAGKLLPAGIGAVIGAGGNRFIGKRIITNARNAFGEPP
Mflv_0802|M.gilvum_PYR-GCK FVTKYGTKRGIIAIGKVAPFGVGFAIGAGGNLVMARGVIKTARIMFDSAD
. : :** : ** * *:* :*. ** . .: :: .: *. .
Mb1281c|M.bovis_AF2122/97 ARWPVTLHVLPTVRDAS----
Rv1249c|M.tuberculosis_H37Rv ARWPVTLHVLPTVRDAS----
MMAR_4193|M.marinum_M ARWPVTLHVLPNVRDAS----
MUL_4499|M.ulcerans_Agy99 TRWPVTLHVLPNVRDAS----
MAV_1386|M.avium_104 ARWPRALHLVPPIHEAG----
MLBr_01096|M.leprae_Br4923 SRWPATLILLPTVHNAG----
MSMEG_5048|M.smegmatis_MC2_155 PRWPATLHVLPSAQT------
Mvan_4476|M.vanbaalenii_PYR-1 ARWPSPLHLLPAPRP------
TH_1000|M.thermoresistible__bu PRWPAPLHLLPPLPESGTDST
MAB_1394c|M.abscessus_ATCC_199 TAWPVQLRLVAPDS-------
Mflv_0802|M.gilvum_PYR-GCK ALNRSDTGA------------
.