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RKAHDTVEYDEDGDHYDLAALDLGSQDDAADQNGLGDVFGLVDAVSAGADDGKMPMFTVTNPPGTVTVTT CLDGRVHDVALSHSAAVLSEIALADEIVVIAGLATQDARSAQYTVMLDGMREHGHDTVTTRDFLTRDLHL PTPEQARAARAELFTTRYAGEE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0774 | - | - | 100% (163) | hypothetical protein Mflv_0774 |
| M. gilvum PYR-GCK | Mflv_0156 | - | 1e-12 | 34.43% (122) | hypothetical protein Mflv_0156 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3897 | - | 1e-25 | 42.68% (164) | hypothetical protein Mb3897 |
| M. tuberculosis H37Rv | Rv3867 | - | 1e-25 | 42.68% (164) | hypothetical protein Rv3867 |
| M. leprae Br4923 | MLBr_00407 | - | 4e-20 | 44.14% (111) | hypothetical protein MLBr_00407 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5442 | - | 2e-23 | 41.78% (146) | hypothetical protein MMAR_5442 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0058 | - | 3e-41 | 55.36% (168) | hypothetical protein MSMEG_0058 |
| M. thermoresistible (build 8) | TH_2234 | - | 1e-17 | 40.74% (108) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4592 | - | 5e-21 | 49.07% (108) | hypothetical protein MUL_4592 |
| M. vanbaalenii PYR-1 | Mvan_0071 | - | 2e-57 | 72.15% (158) | hypothetical protein Mvan_0071 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0774|M.gilvum_PYR-GCK --MR--------KAHDTVEYDEDG------------DHYDLAALDLGSQD
Mvan_0071|M.vanbaalenii_PYR-1 --MANPPPGFEASGFDASGFHDGG------------DHDDLAALDFSIAG
MSMEG_0058|M.smegmatis_MC2_155 --MG------DGSPYDP-EYDD--------------DHDSLAALDFPGTD
Mb3897|M.bovis_AF2122/97 -------------MVDPPGNDD--------------DHGDLDALDFSAAH
Rv3867|M.tuberculosis_H37Rv -------------MVDPPGNDD--------------DHGDLDALDFSAAH
MMAR_5442|M.marinum_M --------------MDLPGNDD--------------YNQDLGALDFSGGG
MUL_4592|M.ulcerans_Agy99 -------------MVQPRSN----------------AHSNLDALKFSRTA
MLBr_00407|M.leprae_Br4923 MGSRRRINRRLLPMSTFPAWQEFRRDVVVVFPGNDFDRDDCDTVDPWGVG
TH_2234|M.thermoresistible__bu ----------MTSPYDPDAEWDGESGGVG-----DSGDDLAAALDFSAPG
::.
Mflv_0774|M.gilvum_PYR-GCK DAA-DQNGLGDVFGL------------VDAVSAGADDGK------MPMFT
Mvan_0071|M.vanbaalenii_PYR-1 DE--DEADLGVIFG--------------DFGSASDDDGE------MPMFT
MSMEG_0058|M.smegmatis_MC2_155 DEPESSLDVFDVFDVG-----APADEPWDAATSADGDGEDETP--APVFT
Mb3897|M.bovis_AF2122/97 TNEASPLDALDDYAP---VQTDDAEGDLDALHALTERDEEPE---LELFT
Rv3867|M.tuberculosis_H37Rv TNEASPLDALDDYAP---VQTDDAEGDLDALHALTERDEEPE---LELFT
MMAR_5442|M.marinum_M TSEDSGLGALDEYAPPEPQETEQAGADLDALHGLTEKEDEPD---IAMFT
MUL_4592|M.ulcerans_Agy99 DNKESAIDALRAFAP---TQPEEADVDLRALHKPAKDDKAEE---CDLFT
MLBr_00407|M.leprae_Br4923 GAAHWTIDPIVGFASS--SAPQDRGTDVDNTRGQAEEDEKQKEPEVAIFT
TH_2234|M.thermoresistible__bu EDDADVDDLYVAEPEP-----EEPAEGYVDPYEQAEEPEDLG----PLFS
. . :*:
Mflv_0774|M.gilvum_PYR-GCK VTNPPGTVTVTTCLDGRVHDVALSHSAAVLSEIALADEIVVIAGLATQDA
Mvan_0071|M.vanbaalenii_PYR-1 VTNPPGTVTVTTYMDGRVHQIELAPSAAALPEAVLADEIVVIAGLATQDA
MSMEG_0058|M.smegmatis_MC2_155 VTNPPGTVTVAAYLDGRVHQIALSPKVVNMTERELADEIRVIADLAGEQA
Mb3897|M.bovis_AF2122/97 VTNPQGSVSVSTLMDGRIQHVELTDKATSMSEAQLADEIFVIADLARQKA
Rv3867|M.tuberculosis_H37Rv VTNPQGSVSVSTLMDGRIQHVELTDKATSMSEAQLADEIFVIADLARQKA
MMAR_5442|M.marinum_M VTNPQGSVSVTTMMGGIVQQVTVTDKAANMSESALAEEIFVIADLARQKA
MUL_4592|M.ulcerans_Agy99 VTNPQGTVSVSAVLGGKIRRVELSEEVTTMAEPNLAAEIYVIADLARQKA
MLBr_00407|M.leprae_Br4923 VTNPPRTVSVSVLMDGRIDHVELSKRVTWMSESQVASEILVLADLARQKA
TH_2234|M.thermoresistible__bu VTNPPGTLTVTAFLDGGIQSVEISPSVTGMTESELAQELLAIAKVAAMKA
**** :::*:. :.* : : :: .. :.* :* *: .:* :* .*
Mflv_0774|M.gilvum_PYR-GCK RSAQYTVMLDGMR-----EHGHDTVTTRDFLTRDLHLPTPEQARAARAEL
Mvan_0071|M.vanbaalenii_PYR-1 RSAQYTFMLEGMR-----EHGHDNVTTRDFLNRDLDLPTPEQARAARAEL
MSMEG_0058|M.smegmatis_MC2_155 RSAQYSFMLEGMR-----EHGHDDAATRDFLTRDLNLPTPEQADANQAQV
Mb3897|M.bovis_AF2122/97 RASQYTFMVENIG-ELTDEDAEGSALLREFVGMTLNLPTPEEAAAAEAEV
Rv3867|M.tuberculosis_H37Rv RASQYTFMVENIG-ELTDEDAEGSALLREFVGMTLNLPTPEEAAAAEAEV
MMAR_5442|M.marinum_M RAAQHTFMVEAMASELSDETEEEGALLREFVGMTLNLPTPEEAEAAEAEV
MUL_4592|M.ulcerans_Agy99 RAAQHTLMVQSMK---DIESEKHRAKLREFLGTMLNLPTPEQAAAAQKEV
MLBr_00407|M.leprae_Br4923 QSAQYTFILDKLS-QLADGDEHRVALLRESVGNTWNLPSPEQAAEAEAEV
TH_2234|M.thermoresistible__bu RAGQYEFLLEATP-----QEAGEREFLGEFLQHGVGLPTPEQAAQVEAEF
::.*: .::: : : **:**:* . :.
Mflv_0774|M.gilvum_PYR-GCK FTTRYAGEE----------------------------
Mvan_0071|M.vanbaalenii_PYR-1 FTTRYAGDE----------------------------
MSMEG_0058|M.smegmatis_MC2_155 FSTRYGGDHG---------------------------
Mb3897|M.bovis_AF2122/97 FATRYDVDYTSRYKADD--------------------
Rv3867|M.tuberculosis_H37Rv FATRYDVDYTSRYKADD--------------------
MMAR_5442|M.marinum_M FATRYEVDYTSRYNER---------------------
MUL_4592|M.ulcerans_Agy99 FATRYGRESARKSRGNGLDGVPVFARRVSDVHREADW
MLBr_00407|M.leprae_Br4923 FATRYSDYCPAQDTENDQW------------------
TH_2234|M.thermoresistible__bu VQRYLRDDV----------------------------
.