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AAADELRDRVGEKIHFRGADSVTQNDIRRKLEVFTFSCPLHDDEAAAKAHGYLGVVAPVTMTPLWGLPPY WAPGQPSPYLVDGQEMTGNITDTLALPFSRSVNVSSEWQYHTPLYLGDRLQGTTTIISVEQKRTRVGTGI FLQYESEYVKVSGELVARNRNTVFNYDPDDASRPEPGTSARAQQGDRGPRTRSVDDADTSVDWNTPLQFD DVTVGAQVRGPALALTYQRMVMNIAADRMFSGIHHSAAAAHAAGLADIIFNTRGLETLFETGLRRWMGLR GRLVQLGPFKMSASVHPGDVVQARWTVTGKHAQAGADVVDLEFGVFAGDRQAAQGVAAIHLNGKKQC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0552 | - | - | 100% (348) | hypothetical protein Mflv_0552 |
| M. gilvum PYR-GCK | Mflv_0634 | - | 0.0 | 100.00% (348) | hypothetical protein Mflv_0634 |
| M. gilvum PYR-GCK | Mflv_0994 | - | 1e-06 | 23.45% (307) | dehydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2057 | - | 2e-09 | 26.47% (136) | hypothetical protein MAB_2057 |
| M. marinum M | MMAR_3967 | - | 9e-13 | 30.56% (144) | hypothetical protein MMAR_3967 |
| M. avium 104 | MAV_1641 | - | 1e-11 | 31.30% (131) | hypothetical protein MAV_1641 |
| M. smegmatis MC2 155 | MSMEG_5992 | - | 2e-06 | 25.00% (192) | hypothetical protein MSMEG_5992 |
| M. thermoresistible (build 8) | TH_0364 | - | 9e-06 | 25.12% (207) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3823 | - | 1e-12 | 29.86% (144) | hypothetical protein MUL_3823 |
| M. vanbaalenii PYR-1 | Mvan_0531 | - | 0.0 | 100.00% (348) | hypothetical protein Mvan_0531 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5992|M.smegmatis_MC2_155 ----MTTQVNEDLQAGIEKIKAEGK-SDPRKGRDPVNQPMIHHWVDAIGD
TH_0364|M.thermoresistible__bu ----MS-----ELQSAIDEIKAAGT-SAPRKGRDPVNQPMIHHWVDAIGD
MMAR_3967|M.marinum_M MAPGSQVGYRLAFGTYQDALQMVGTASPPRTAATAVSGARIQLFAALVHD
MUL_3823|M.ulcerans_Agy99 ------MGYRLAFGTYQDALQMVGTTSPPRTAATAVSGARIQLFAALVHD
MAV_1641|M.avium_104 --MDQDFGRRLAFGTYEDALRMVGAKGQPRTAGTAVSAARIQLFAAMVRD
Mflv_0552|M.gilvum_PYR-GCK -------------MAAADELRDRVGEKIHFRGADSVTQNDIRRKLEVFTF
Mvan_0531|M.vanbaalenii_PYR-1 -------------MAAADELRDRVGEKIHFRGADSVTQNDIRRKLEVFTF
MAB_2057|M.abscessus_ATCC_1997 ----MNGSTEHSMVRFPVRFEDIAVGDTLTPVSIEISYKRICMNAASTWD
:. :. *
MSMEG_5992|M.smegmatis_MC2_155 KNPIYVDQEAAKAAGHPGIVAPPAMIQVWTMGGLGA------GRSDDDPL
TH_0364|M.thermoresistible__bu RNPIYVDDEAARAVGHPGVVAPPAMIQVWTMGGLGE------GRPDDDPL
MMAR_3967|M.marinum_M GNRSYWDEDYARAHWG-GLLAPPALLMGWLTTPP--------WQPGERDS
MUL_3823|M.ulcerans_Agy99 GNRSYWDEDYARAHWG-GLLAPPALLMGWLTTPP--------WQPAERDS
MAV_1641|M.avium_104 GNRSYWDSAFAQRHWG-GLLAPPALLMGWLIAPP--------WQPDGRPS
Mflv_0552|M.gilvum_PYR-GCK SCPLHDDEAAAKAHGYLGVVAPVTMTPLWGLPPYWAPGQPSPYLVDGQEM
Mvan_0531|M.vanbaalenii_PYR-1 SCPLHDDEAAAKAHGYLGVVAPVTMTPLWGLPPYWAPGQPSPYLVDGQEM
MAB_2057|M.abscessus_ATCC_1997 WFPGHHDPDYARSQGQRTIYLSTLFFHGFIDRGLN---------------
: * *: : . : :
MSMEG_5992|M.smegmatis_MC2_155 SKIMKLFDDAGYVGVVATNCEQTYHRYLQPGEELTIHAEITDVVGPKQTA
TH_0364|M.thermoresistible__bu SKMMRLFDDAGFVGVVATNCDQTYHRYLRPGEEVTINAEITDVIGPKQTA
MMAR_3967|M.marinum_M AGSLALRVPLPGTTFINAANDVEFLQPIVEGDRLCVVEELVSVSPEKRTR
MUL_3823|M.ulcerans_Agy99 AGSLALRVPLPGTAFINAANDVEFLQPIVEGDRLCVVEQLVSVSPEKRTR
MAV_1641|M.avium_104 ASLIALRVPLPGTTFINAANEVEFPHPIVEGDVLTVVDELVSVSPEKRTR
Mflv_0552|M.gilvum_PYR-GCK TGNITDTLALPFSRSVNVSSEWQYHTPLYLGDRLQGTTTIISVE-QKRTR
Mvan_0531|M.vanbaalenii_PYR-1 TGNITDTLALPFSRSVNVSSEWQYHTPLYLGDRLQGTTTIISVE-QKRTR
MAB_2057|M.abscessus_ATCC_1997 --------EWAGPDALIRRRRISMIRSIYPGQTATLSGKVVAKRDDGGRR
: : *: :
MSMEG_5992|M.smegmatis_MC2_155 LGEGYFINQLITWTTEEGEAVAEMNWRIMKFKPREDQK-PAVPDDLDPDK
TH_0364|M.thermoresistible__bu LGEGYFINQHITWQVDGGETVAEMDWRIMKFRPREKTTGPVVPDDLDPEK
MMAR_3967|M.marinum_M LGVGHFVETLETYRRQDAMVVARARNTLFRFTPGPSS-------------
MUL_3823|M.ulcerans_Agy99 LGVGHFVETLETYRRQDAVVVARSRNTLFRFTPGPSS-------------
MAV_1641|M.avium_104 LGVGHFVETLETYRRQDGTVVATSRNTLFRFTPGPSS-------------
Mflv_0552|M.gilvum_PYR-GCK VGTGIFLQYESEYVKVSGELVARNRNTVFNYDPDDASRPEPGTSARAQQG
Mvan_0531|M.vanbaalenii_PYR-1 VGTGIFLQYESEYVKVSGELVARNRNTVFNYDPDDASRPEPGTSARAQQG
MAB_2057|M.abscessus_ATCC_1997 LVDLELLVSSEDGPCVPSEATVELADPFVEVPG-----------------
: :: . .. ...
MSMEG_5992|M.smegmatis_MC2_155 LMRP----------ASSRDTQFFWDGVNAHELRIQRRPDGTLQHPPVPAV
TH_0364|M.thermoresistible__bu LMRP----------APSRDTQFFWDGVNAHELRIQRLPDGTLQHPPVPAV
MMAR_3967|M.marinum_M --------------------------------------------------
MUL_3823|M.ulcerans_Agy99 --------------------------------------------------
MAV_1641|M.avium_104 --------------------------------------------------
Mflv_0552|M.gilvum_PYR-GCK DRGPRTRSVDDADTSVDWNTPLQFDDVTVGAQVRGPALALTYQRMVMNIA
Mvan_0531|M.vanbaalenii_PYR-1 DRGPRTRSVDDADTSVDWNTPLQFDDVTVGAQVRGPALALTYQRMVMNIA
MAB_2057|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5992|M.smegmatis_MC2_155 WQDKEQPIDYVVASGNGTVFSYVVHHAPKVPGRTLPFVIALVELEEGVRM
TH_0364|M.thermoresistible__bu WQDKSEEVDYVVAGGRGTVFSFVVHHAPKVPGRTLPFVIALVELDEGVRM
MMAR_3967|M.marinum_M --------------------------------------------------
MUL_3823|M.ulcerans_Agy99 --------------------------------------------------
MAV_1641|M.avium_104 --------------------------------------------------
Mflv_0552|M.gilvum_PYR-GCK ADRMFSGIHHSAAAAHAAGLADIIFNTRGLETLFETGLRRWMGLRGRLVQ
Mvan_0531|M.vanbaalenii_PYR-1 ADRMFSGIHHSAAAAHAAGLADIIFNTRGLETLFETGLRRWMGLRGRLVQ
MAB_2057|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5992|M.smegmatis_MC2_155 LGELRN----VDPDQVQIGMPVRATFIDFPDSEISPAWTLYAWEPRA---
TH_0364|M.thermoresistible__bu LGELRN----VDPAAVQIGMPVRVMFIDLPETESGPSWTLYAWEPDT---
MMAR_3967|M.marinum_M --------------------------------------------------
MUL_3823|M.ulcerans_Agy99 --------------------------------------------------
MAV_1641|M.avium_104 --------------------------------------------------
Mflv_0552|M.gilvum_PYR-GCK LGPFKMSASVHPGDVVQARWTVTGKHAQAGADVVDLEFGVFAGDRQAAQG
Mvan_0531|M.vanbaalenii_PYR-1 LGPFKMSASVHPGDVVQARWTVTGKHAQAGADVVDLEFGVFAGDRQAAQG
MAB_2057|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5992|M.smegmatis_MC2_155 ------------
TH_0364|M.thermoresistible__bu ------------
MMAR_3967|M.marinum_M ------------
MUL_3823|M.ulcerans_Agy99 ------------
MAV_1641|M.avium_104 ------------
Mflv_0552|M.gilvum_PYR-GCK VAAIHLNGKKQC
Mvan_0531|M.vanbaalenii_PYR-1 VAAIHLNGKKQC
MAB_2057|M.abscessus_ATCC_1997 ------------