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TLNESVPAALPVVERPINDVVVDVPTGRRARRGDDGMLGLGLLAGPANVIMQLARPAVGYGVLESRVESG RVDRHPIKRARTTFTYLAVSTNGTPEQQKAFRRAVNGAHAQVFSTDESPVKYHAFDKDLQLWVGACLYKG VVDVHRLFVGEMDEETADRVYVQGRALATMLQVPESMWPADREAFDRYWAASLDEVHIDDTVREYLYPIA ASRLRGLRLPGPLQRRNEELALLITTGFLPQRFRDEMRLPWGPDHQRRFDRLMKVLRVANTVSPKFVRQF PFNLLLKDVDRRIRTGRPLV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0330 | - | - | 100% (301) | hypothetical protein Mflv_0330 |
| M. gilvum PYR-GCK | Mflv_0423 | - | 1e-61 | 46.62% (281) | hypothetical protein Mflv_0423 |
| M. gilvum PYR-GCK | Mflv_0060 | - | 3e-09 | 22.27% (229) | hypothetical protein Mflv_0060 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0282 | - | 1e-113 | 67.23% (296) | hypothetical protein Mb0282 |
| M. tuberculosis H37Rv | Rv0276 | - | 1e-112 | 67.23% (296) | hypothetical protein Rv0276 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4329c | - | 6e-82 | 56.04% (273) | hypothetical protein MAB_4329c |
| M. marinum M | MMAR_0537 | - | 1e-114 | 67.00% (303) | hypothetical protein MMAR_0537 |
| M. avium 104 | MAV_4880 | - | 1e-111 | 68.42% (285) | hypothetical protein MAV_4880 |
| M. smegmatis MC2 155 | MSMEG_0613 | - | 1e-109 | 65.44% (298) | hypothetical protein MSMEG_0613 |
| M. thermoresistible (build 8) | TH_4513 | - | 2e-71 | 67.37% (190) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1201 | - | 1e-112 | 65.78% (301) | hypothetical protein MUL_1201 |
| M. vanbaalenii PYR-1 | Mvan_0410 | - | 1e-145 | 82.89% (304) | hypothetical protein Mvan_0410 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0282|M.bovis_AF2122/97 MAISLVAHQ------------PIPHVERPMADPPRLQLARRRRSAAGPGG
Rv0276|M.tuberculosis_H37Rv MAISLVAHQ------------PIPHVERPMADPPRLQLARRRRSAAGPGG
MMAR_0537|M.marinum_M MTIQEAAGR------------LAPHVERPISDPPR-QVRRRKR-----GG
MUL_1201|M.ulcerans_Agy99 MTIQEAAGR------------LAPHVERPISDPPR-QVRQRKR-----GG
MAV_4880|M.avium_104 MAIHEPVHQPTAHVEPTGHVEPTSHVERRVTDPPRPRRRKPLR----TLG
Mflv_0330|M.gilvum_PYR-GCK MTLNESVPA------------ALPVVERPINDVVVDV-PTGRRA---RRG
Mvan_0410|M.vanbaalenii_PYR-1 MTLDESVSA------------PVPLVERPVSESSVPAGPRARVS---TRS
MSMEG_0613|M.smegmatis_MC2_155 --MAMTVSE------------PIPYVERGMSESAGPAPVRRRRR---KAT
TH_4513|M.thermoresistible__bu --------------------------------------------------
MAB_4329c|M.abscessus_ATCC_199 MVTIEQVSEAEAQLAGDGGPGTRSRRNEPVPPAAPLSPWWSWRR---RPT
Mb0282|M.bovis_AF2122/97 NEDSLMGVALLAGPANVIMELAMPGVGYGVLESRVESGRLDRHPIKRART
Rv0276|M.tuberculosis_H37Rv NEDSLMGVALLAGPANVIMELAMPGVGYGVLESRVESGRLDRHPIKRART
MMAR_0537|M.marinum_M FGDGLMGVALLAGPANVIMELARPGVGHGVMESRVESGRIDRHPIKRART
MUL_1201|M.ulcerans_Agy99 FGNGLMGVALLAGPANVIMELARPGVGHGVMESRVESGRIDRHPIKRART
MAV_4880|M.avium_104 IDEGLMGVALLAGPANVIMQLANPGVGYGVMESRVESGRVDLHPIKRART
Mflv_0330|M.gilvum_PYR-GCK -DDGMLGLGLLAGPANVIMQLARPAVGYGVLESRVESGRVDRHPIKRART
Mvan_0410|M.vanbaalenii_PYR-1 -DDGMLGLGLLAGPANVIMQLARPGVGYGVLESRVESGRIDRHPVKRART
MSMEG_0613|M.smegmatis_MC2_155 FDDGLMGVALLAGPANVIMQLANPGVGYGVVESRVDSGRTDLHPVKRART
TH_4513|M.thermoresistible__bu --------------------------------------------------
MAB_4329c|M.abscessus_ATCC_199 VADNFMGLALLGGPANIIMQLARPGVGYGVVDSKVESGRADLHPIKRART
Mb0282|M.bovis_AF2122/97 TFTYVAVAVAGSDDQKAAFRRAVNKVHAQVYSTPESPVSYHAFDPELQLW
Rv0276|M.tuberculosis_H37Rv TFTYVAVAVAGSDDQKAAFRRAVNKVHAQVYSTPESPVSYHAFDPELQLW
MMAR_0537|M.marinum_M TFTYVAVASAGTDEQKAAFRRAVNRVHAQVYSTPESPVSYSAFDVELQLW
MUL_1201|M.ulcerans_Agy99 TFTYVAVASAGTDEQKAAFRRAVNRVHAQVYSTPESPVSYSAFDVELQLW
MAV_4880|M.avium_104 TFTYLAVATSGSEAQKDAFRRAVNRAHAQVYSTPESPVSYNAFDPNLQLW
Mflv_0330|M.gilvum_PYR-GCK TFTYLAVSTNGTPEQQKAFRRAVNGAHAQVFSTDESPVKYHAFDKDLQLW
Mvan_0410|M.vanbaalenii_PYR-1 TFTYLAVSTNGTPEQQAAFRRAVNRAHAQVFSTDESPVKYHAFDKDLQLW
MSMEG_0613|M.smegmatis_MC2_155 TFTYLAVATRGTEAQKAAFRRAVNKAHAQVYSTEDSPVQYNAFDKNLQLW
TH_4513|M.thermoresistible__bu -----------------------------VFSTDESPVSYNAFDKDLQLW
MAB_4329c|M.abscessus_ATCC_199 TFTFLAVATLGTPEQKAAFRKATNRAHAQVHSQPGDKVQYNAFDPELQKW
*.* . *.* *** :** *
Mb0282|M.bovis_AF2122/97 VAACLYKGGVDVYRTFVGEMDDEEADHHYRAGMAMGTTLQVPPQMWPPDR
Rv0276|M.tuberculosis_H37Rv VAACLYKGGVDVYRTFVGEMDDEEADHHYRAGMAMGTTLQVPPQMWPPDR
MMAR_0537|M.marinum_M VAACLYKGGVDIYRTFVGEMDDEEADRHYRDGMSMGTTLQVPAELWPPDR
MUL_1201|M.ulcerans_Agy99 VAACLYKGGVDIYRTFVGEMDDEEADRHYRDGMSMGTTLQVPAELWPPDR
MAV_4880|M.avium_104 VGACLYKGGLDIYRMFIGELDGDDADRHYREGMTLATTLQVPPAMWPPDR
Mflv_0330|M.gilvum_PYR-GCK VGACLYKGVVDVHRLFVGEMDEETADRVYVQGRALATMLQVPESMWPADR
Mvan_0410|M.vanbaalenii_PYR-1 VGACLYKGVVDVHRLFVGEMDEETADRLYLQGRALATMLQVPEDMWPADR
MSMEG_0613|M.smegmatis_MC2_155 VAACLYKGGVDVLRMFVGEMDDETADRHYRDSVTMGTTLQVPAEMWPADR
TH_4513|M.thermoresistible__bu VAACLYKGGVDVFRMFVGEMDDDTADQHYRDSMSMATTLQVPPEMWPADR
MAB_4329c|M.abscessus_ATCC_199 VAVCLYKGFVDVYEAFVGPLTGETAERCLQEGAVMGTTLQMPLAMWPKSC
*..***** :*: . *:* : : *:: . :.* **:* :** .
Mb0282|M.bovis_AF2122/97 AAFDRYWRQSLD-RVHIDDVVRDYLYPIVALRIRGIALPGPLRRLSEGIA
Rv0276|M.tuberculosis_H37Rv AAFDRYWRQSLD-RVHIDDVVRDYLYPIVALRIRGIALPGPLRRLSEGIA
MMAR_0537|M.marinum_M AAFDRYWQESLQ-KIHIDDAVREYLYPIAASRVRGVALPGPLRRWSEGLA
MUL_1201|M.ulcerans_Agy99 AAFDRYWQESLQ-KIHIDDAVREYLYPIAASRVRGVALPGPLRRWSEGLA
MAV_4880|M.avium_104 AAFDRYWEESLA-KVHIDDAVREYLYPIAANRIRGVWLPGPVRRLTEGFA
Mflv_0330|M.gilvum_PYR-GCK EAFDRYWAASLD-EVHIDDTVREYLYPIAASRLRGLRLPGPLQRRNEELA
Mvan_0410|M.vanbaalenii_PYR-1 AAFDRYWQESLD-DVHIDDTVREFLYPIAATRLRGLALPGPLQRQTEKLA
MSMEG_0613|M.smegmatis_MC2_155 AAFDRYWNEQIE-KVHIDDTVRAYLYPIAAGRPKATKLPRFIQKRLDGIA
TH_4513|M.thermoresistible__bu AAFDKYWQEQLETKIHIDDTVRGYLYPIAAGRPKSSPLPKAVQRRLDSVG
MAB_4329c|M.abscessus_ATCC_199 AEFDEYWAQSMD-LVHIDDHVRPYLYRIAS---ASIAVPPFMRGPVGAFS
**.** .: :**** ** :** *.: . :* :: ..
Mb0282|M.bovis_AF2122/97 LLITTGFLPQRFRDEMRLPWDATKQRRFDALMAVLRTVNRLMPRFVREFP
Rv0276|M.tuberculosis_H37Rv LLITTGFLPQRFRDEMRLPWDATKQRRFDALMAVLRTVNRLMPRFVREFP
MMAR_0537|M.marinum_M LLITTGFLPQRFRDEMRLPWDAAKQRRFDRLIAVVGALNRMMPRIVREFP
MUL_1201|M.ulcerans_Agy99 LLITTGFLPQRFRDEMRLPWDAAKQRRFDRLIAMVGALNRMMPRIVREFP
MAV_4880|M.avium_104 LFITTGFLPQRFRDEMRLPWDSTKQRRFDRLIAVLATVNRYLPRFIRQFP
Mflv_0330|M.gilvum_PYR-GCK LLITTGFLPQRFRDEMRLPWGPDHQRRFDRLMKVLRVANTVSPKFVRQFP
Mvan_0410|M.vanbaalenii_PYR-1 LLITTGFLPQRFREEMQLPWDAGQQRRFDRLMAALRAVNSVSPKFVRQFP
MSMEG_0613|M.smegmatis_MC2_155 LLITTGFLPQRFRDEMRLPWDEKRQQRFDRLIAVLRFVNDLLPAPVRAFP
TH_4513|M.thermoresistible__bu LLITTGFLPQRFRDEMRLPWDAGRQRRFDRLIAALRAGNDLAPSVVRQFP
MAB_4329c|M.abscessus_ATCC_199 RFITTGFLPQRFRDEMGFAWDPSRERMFRWLLAVLGLAARLLPNGLRRFP
:***********:** :.*. ::: * *: : * :* **
Mb0282|M.bovis_AF2122/97 FNLMLWDLDRRMRRGRPLV
Rv0276|M.tuberculosis_H37Rv FNLMLWDLDRRMRRGRPLV
MMAR_0537|M.marinum_M FNLMLWDLDRRIRTGRRLV
MUL_1201|M.ulcerans_Agy99 FNFMLWDLDRRIRTGRRLV
MAV_4880|M.avium_104 FNVLLYDLDRRIRKGRPLV
Mflv_0330|M.gilvum_PYR-GCK FNLLLKDVDRRIRTGRPLV
Mvan_0410|M.vanbaalenii_PYR-1 FNVLLKDLDWRVRTGRPLV
MSMEG_0613|M.smegmatis_MC2_155 FNALLKDLDWRIRTGRSLV
TH_4513|M.thermoresistible__bu FNVLLRDLDWRRRTGRPLV
MAB_4329c|M.abscessus_ATCC_199 FNALMLDLDWRIRTGRPLV
** :: *:* * * ** **