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VGMRSAARMPKLTRRSRILIMIALGVIVLLLAGPRLIDAYVDWLWFGELGYRSVFTTMLATRIVVCLVAG VVVGGIVFGGLALAYRTRPVFVPDADNDPVARYRAVVLARLRLVGIGIPAAIGLLAGIVAQSYWARIQLF LHGGDFGVRDPQFGRDLGFYAFELPFYRLMLSYMLVSVFLAFVANLVAHYIFGGIRLSGRTGALSRSARV QLVSLVGVLVLLKAVAYWLDRYELLSHTRGGKPFTGAGYTDINAVLPAKLILMAIALICAAAVFSAIALR DLRIPAIGLVLLLLSSLIVGAGWPLIVEQISVKPNAAQKESEYISRSITATRQAYGLTSDVVTYRNYSGD SPATAQQVAADRATTSNIRLLDPTIVSPAFTQFQQGKNFYYFPDQLSIDRYLDRNGNLRDYVVAARELNP DRLIDNQRDWINRHTVYTHGNGFIASPANTVRGIANDPNQNGGYPEFLVNVVGANGTVVSDGPAPLDQPR IYFGPVISNTSADYAIVGRNGDDREYDYETNIDTKRYTYTGSGGVPLGGWLARSVFAAKFAERNFLFSNV IGSNSKILFNRDPAQRVEAVAPWLTTDSAVYPAIVNKRLVWIVDGYTTLDNYPYSELTSLSSATADSNEV AFNRLVPDKKVSYIRNSVKATVDAYDGTVTLYQQDEKDPVLKAWMQVFPGTVKPKSDIAPELAEHLRYPE DLFKVQRMLLAKYHVNDPVTFFSTSDFWDVPLDPNPTASSYQPPYYIVAKNIAKDDNSASYQLISAMNRF KRDYLAAYISASSDPATYGNLTVLTIPGQVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLP VAQGGLLYVEPVYASPGASDAASSYPRLIRVAMMYNDKVGYGPTVRDALTGLFGPGAGATATGIAPTEAA VPPSPAANPPPPASGPQPPPVTAAPPVPVGAVTLSPAKVAALQEIQAAIGAARDAQKKGDFAAYGSALQR LDEAITKFNDAG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3215c | - | - | 100% (992) | hypothetical protein Mb3215c |
M. bovis AF2122 / 97 | Mb0065 | - | 0.0 | 50.30% (986) | hypothetical protein Mb0065 |
M. bovis AF2122 / 97 | Mb1284c | lprE | 2e-05 | 40.74% (54) | lipoprotein LprE |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_4654 | - | 0.0 | 77.47% (1003) | hypothetical protein Mflv_4654 |
M. tuberculosis H37Rv | Rv3193c | - | 0.0 | 99.90% (992) | hypothetical protein Rv3193c |
M. leprae Br4923 | MLBr_00644 | - | 0.0 | 86.35% (989) | hypothetical protein MLBr_00644 |
M. abscessus ATCC 19977 | MAB_3498c | - | 0.0 | 70.77% (999) | hypothetical protein MAB_3498c |
M. marinum M | MMAR_1371 | - | 0.0 | 89.63% (993) | transmembrane protein |
M. avium 104 | MAV_4137 | - | 0.0 | 90.31% (991) | hypothetical protein MAV_4137 |
M. smegmatis MC2 155 | MSMEG_1959 | - | 0.0 | 79.38% (1004) | hypothetical protein MSMEG_1959 |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_2505 | - | 0.0 | 89.22% (993) | hypothetical protein MUL_2505 |
M. vanbaalenii PYR-1 | Mvan_1814 | - | 0.0 | 79.98% (999) | hypothetical protein Mvan_1814 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4654|M.gilvum_PYR-GCK MGMRPAARMPSLTQRSRFLIAVSAVLVLLLLLGPRFIDTYVDWLWFGELG Mvan_1814|M.vanbaalenii_PYR-1 --MRPAARMPNLTRRSRVMIAVALAVVVLLLLGPRLVDTYVNWLWFGELG MSMEG_1959|M.smegmatis_MC2_155 MGMRPTARMPKLTRRSRVLIAFALVAVLLLLLGPRLIDTYVDWLWFGELG Mb3215c|M.bovis_AF2122/97 MGMRSAARMPKLTRRSRILIMIALGVIVLLLAGPRLIDAYVDWLWFGELG Rv3193c|M.tuberculosis_H37Rv MGMRSAARMPKLTRRSRILIMIALGVIVLLLAGPRLIDAYVDWLWFGELG MMAR_1371|M.marinum_M MGMRPTARMPKLTRRSRVLILIALGVIALLLAGPRLIDAYVDWLWFGELG MUL_2505|M.ulcerans_Agy99 MGMRPTARMPKLTRRSRVLILIALGVIALLLAGPRLIDAYVDWLWFGELG MAV_4137|M.avium_104 MGMRPTARMPKLTRRSRILILIALGVIALLLAGPRLIDAYVDWLWFGELG MLBr_00644|M.leprae_Br4923 MGMRPAARMPKLTRRSRTLIMVALGVIVLLLAGPRLVDAYVEWLWFGELG MAB_3498c|M.abscessus_ATCC_199 MGMRPNGALPRLTRRSRRLVAASLVIVVLLLIGPRLVDTYINWLWFGELG **. . :* **:*** :: : : *** ***::*:*::******** Mflv_4654|M.gilvum_PYR-GCK YRSVFTTQIITRLVIFFVVAILVGAVVFAGLALAYRTRPVFVPTAGPNDP Mvan_1814|M.vanbaalenii_PYR-1 YRSVFTTQIVTRLLLFLAVAVVFGAVVFAAMALAYRTRPVFVPTAGPNDP MSMEG_1959|M.smegmatis_MC2_155 YRSVFTTVLATRLIVFVVVALAIGAIVFAGLALAYRTRPVFVPTAGPNDP Mb3215c|M.bovis_AF2122/97 YRSVFTTMLATRIVVCLVAGVVVGGIVFGGLALAYRTRPVFVPDAD-NDP Rv3193c|M.tuberculosis_H37Rv YRSVFTTMLATRIVVCLVAGVVVGGIVFGGLALAYRTRPVFVPDAD-NDP MMAR_1371|M.marinum_M YRSVFTTVLVTRFLVFLVAGVLVGGIVFAGLALAYRTRPVFVPNND-NDP MUL_2505|M.ulcerans_Agy99 YLSVFTTVLVTRFLVFLVAGVLVGGIVFAGLALAYRTRPVFVPNND-NDP MAV_4137|M.avium_104 YRSVFSTVLVTRFVVFLIAGLLVGGIVFAGLAVAYRTRPVFVPSND-NDP MLBr_00644|M.leprae_Br4923 YRSVFSTVLVTRVVVFLVAGLVVGGIVFAGLAVAYRTRPVFVPSHD-NDP MAB_3498c|M.abscessus_ATCC_199 FRGVFTTVLLTRLALFLIVGTLVAAVVFAGFGLAYRARPVFVPAKGPGDA : .**:* : **. : . .. ...:**..:.:***:****** . .*. Mflv_4654|M.gilvum_PYR-GCK IARYRTAVMARLRLIGIGVPLAIGVLAGFVGQSYWQRVQLFLHGGDFGVS Mvan_1814|M.vanbaalenii_PYR-1 IARYRTAVMARLRLVGIGVPVAVGLLAGLIAQNYWQRVQLFLHGGSFGVS MSMEG_1959|M.smegmatis_MC2_155 VARYRTTVMARLRLFGIGVPVFIGLLAGIVAQSYWVKIQLFLHGGDFGIT Mb3215c|M.bovis_AF2122/97 VARYRAVVLARLRLVGIGIPAAIGLLAGIVAQSYWARIQLFLHGGDFGVR Rv3193c|M.tuberculosis_H37Rv VARYRAVVLARLRLVGIGIPAAIGLLAGIVAQSYWARIQLFLHGGDFGVR MMAR_1371|M.marinum_M VARYRTVVLARLRLFGIGIPAAIGLLAGIVAQSYWVRIQLFLHGGDFGIT MUL_2505|M.ulcerans_Agy99 VARYRTVVLARLRLFGIGIPAAIGLLAGIVAQSYWVRIQLFLHGGDFGIT MAV_4137|M.avium_104 VARYRALVLSRLRLVSIGVPVAIGLLAGIIAQSYWVRIQLFLHGGDFGIK MLBr_00644|M.leprae_Br4923 VARYRAMALSRLRLIGVGIPAAIGLLAGIIAQSYWVRIQLFLHGDNFGIR MAB_3498c|M.abscessus_ATCC_199 LAQYRALILSRVRLFLIGVPILIGVLAGVVAQSYWMPVQLFLEGGDFGIK :*:**: ::*:**. :*:* :*:***.:.*.** :****.*..**: Mflv_4654|M.gilvum_PYR-GCK DPQFGIDLGFYAFDLPFYRLVLTYLFVGVFLAFLANLLGHYLFGGIRLAG Mvan_1814|M.vanbaalenii_PYR-1 DPQFGIDLGFYAFDLPFYRLMLTYLFAATFLAFIANLLGHYLFGGIRLAG MSMEG_1959|M.smegmatis_MC2_155 DPEFGKDLGFYAFDLPFYRLVLTYLFVATFLAFVANLLGHYLFGGIRLTG Mb3215c|M.bovis_AF2122/97 DPQFGRDLGFYAFELPFYRLMLSYMLVSVFLAFVANLVAHYIFGGIRLSG Rv3193c|M.tuberculosis_H37Rv DPQFGRDLGFYAFELPFYRLMLSYMLVSVFLAFVANLVAHYIFGGIRLSG MMAR_1371|M.marinum_M DPQFGKDLGFYAFELPFYRLLLSYLFVAIFLAFVANVVSHYLFGGIRLTG MUL_2505|M.ulcerans_Agy99 DPQFGKDLGFYAFELPFYRLLLSYLFVAIFLAFVANVVSHYLFGGIRLTG MAV_4137|M.avium_104 DPQFGKDLGFYAFELPFYRLLLSYLFVAVFLAFVANLLAHYIFGGIRLSG MLBr_00644|M.leprae_Br4923 DPQFGKDLGFYAFELPFYRLVLSYVFVAVFLAFVVNLLAHYIFGGIRLSG MAB_3498c|M.abscessus_ATCC_199 DPQFGLDLGFFAFDLPFYRFVLTYLFIAASIALIVNGLVHYIFGGIRLSG **:** ****:**:*****::*:*:: . :*::.* : **:******:* Mflv_4654|M.gilvum_PYR-GCK RSGALSRAARIQLITLVGLLMLLKAVAYWFDRYELLSHTRGGKPFTGAGY Mvan_1814|M.vanbaalenii_PYR-1 RSGALSRAARIQLIALVGFLMLLKAVAYWLDRYELLSHTRGGKPFTGAGY MSMEG_1959|M.smegmatis_MC2_155 RVGALSRAARIQLISLAGTLIVLKAFAYWLDRYELLSNDRSAKPFTGAGY Mb3215c|M.bovis_AF2122/97 RTGALSRSARVQLVSLVGVLVLLKAVAYWLDRYELLSHTRGGKPFTGAGY Rv3193c|M.tuberculosis_H37Rv RTGALSRSARVQLVSLVGVLVLLKAVAYWLDRYELLSHTRGGKPFTGAGY MMAR_1371|M.marinum_M RSGALSRSARIQLVSLVGVLVLLKAVAYWLDRYELLSHTRGGKPFTGAGY MUL_2505|M.ulcerans_Agy99 RSGALSRSARIQLVSLVGVLVLLKTVAYWLNRYELLSHTRGGKPFTGAGY MAV_4137|M.avium_104 RTGALSRSARIQLVTLVGLLVLLKAVAYWLDRYELLSHTRGGKPFTGAGY MLBr_00644|M.leprae_Br4923 RTGALSRLARLQLVSLVGVLVLLKAVAYWLDRYELLSRTRSSKPFTGAGY MAB_3498c|M.abscessus_ATCC_199 RSGTLSRPARIQLITFAGILVLLKVAAYWLDRYELLSHTRAGKPFTGAGY * *:*** **:**:::.* *::**. ***::******. *..******** Mflv_4654|M.gilvum_PYR-GCK TDINAVLPAKLILMAIAVICAVAVFSAIFLRDLRIPAIGVVLLLLSSLVV Mvan_1814|M.vanbaalenii_PYR-1 TDINAVLPAKLILMVIAVICAAAVFSAIVLRDLRIPAIGVVLLLLSSLIV MSMEG_1959|M.smegmatis_MC2_155 TDINAVLPAKLIMLAIAVICAVAVFSALVLRDLRIPAIGVALLLLSSLVV Mb3215c|M.bovis_AF2122/97 TDINAVLPAKLILMAIALICAAAVFSAIALRDLRIPAIGLVLLLLSSLIV Rv3193c|M.tuberculosis_H37Rv TDINAVLPAKLILMAIALICAAAVFSAIALRDLRIPAIGLVLLLLSSLIV MMAR_1371|M.marinum_M TDINAVLPAKLILMAIAVICAAAVFSAIVLRDLRIPAIGLVLLLLSSLIV MUL_2505|M.ulcerans_Agy99 TDINAVLPAKLILMAIAVICAAAVFSAIVLRDLRIPAIGLVLLLLSSLIV MAV_4137|M.avium_104 TDINAVLPAKLILMAIALICAAAVFSAITMRDLRIPAIGLVLLLLSSLIV MLBr_00644|M.leprae_Br4923 TDINAVQPAKLILIAIALICAAAVFSAITLRDFRIPAIGLVLLMLSSLIV MAB_3498c|M.abscessus_ATCC_199 TDINAVLPAKLILLAIAVICAVAVFSALVLKDLRIPAIGLALLLLSSLVV ****** *****::.**:***.*****: ::*:******:.**:****:* Mflv_4654|M.gilvum_PYR-GCK GAGWPLVVEQISVRPNAAQKESEYISRSITATRQAYGLTEESVTYRDYPG Mvan_1814|M.vanbaalenii_PYR-1 GAGWPLVVEQISVRPNAAQKESEYISRSITATRQAYGLTDEAVEYRDYPG MSMEG_1959|M.smegmatis_MC2_155 GAGWPLIVEQFSVKPNAAQKEAEYISRSIEATRHAYGLTDETVTYRNYEN Mb3215c|M.bovis_AF2122/97 GAGWPLIVEQISVKPNAAQKESEYISRSITATRQAYGLTSDVVTYRNYSG Rv3193c|M.tuberculosis_H37Rv GAGWPLIVEQISVKPNAAQKESEYISRSITATRQAYGLTSDVVTYRNYSG MMAR_1371|M.marinum_M GAAWPMIVEQISVKPNAAQKESEYISRSITATRQAYGLTSNVVTYRNYTG MUL_2505|M.ulcerans_Agy99 GAAWPMIVEQISVKPNAAQKESEYISRSITATRQAYGLTSNVVTYRNYTG MAV_4137|M.avium_104 GAGWPLIVEQISVKPNAAQKESEYISRSITATRQAYGLTSDVVTYRNYTG MLBr_00644|M.leprae_Br4923 GTGWPLIVEQLIAKPDAVRKESEYIRRSITATRHAYGLTEDVVTYRNYIG MAB_3498c|M.abscessus_ATCC_199 GAGWPLIVEQFSVKPNAAQKESEYIARSIKATRDAYGLTDDVVTYRDYSG *:.**::***: .:*:*.:**:*** *** ***.*****.: * **:* . Mflv_4654|M.gilvum_PYR-GCK NA------SATAQQVAADRATTSNIRVLDPNIVAPAFTQFQQGKNFYFFP Mvan_1814|M.vanbaalenii_PYR-1 NA------TATAQQVAADRATTSNIRVLDPNIVSPAFTQFQQGKNFYFFP MSMEG_1959|M.smegmatis_MC2_155 TG------QTTAAQVAADRATTSNIRLLDPTIVSPAFTQFQQGKNFYYFP Mb3215c|M.bovis_AF2122/97 DS------PATAQQVAADRATTSNIRLLDPTIVSPAFTQFQQGKNFYYFP Rv3193c|M.tuberculosis_H37Rv DS------PATAQQVAADRATTSNIRLLDPTIVSPAFTQFQQGKNFYYFP MMAR_1371|M.marinum_M DG------EATAQQVAADRATTSNIRLLDPTIVSPAFTQFQQGKNFYYFP MUL_2505|M.ulcerans_Agy99 DG------EATAQQVAADRATTSNIRLLDPTIVSPAFTQFQQGKNFYYFP MAV_4137|M.avium_104 DA------QATAQQVADDRATTSNIRLLDPTIVSPAFTQFQQGKNFYYFP MLBr_00644|M.leprae_Br4923 DA------PAIAQQIATDHATTSNIRLLDPTIVSPAFTQFQRGKNFYYFP MAB_3498c|M.abscessus_ATCC_199 TASSPAGSQQLAKQVAADRSTIANIRVLDPNIISPAFTQLQQGKNFYAFP . * *:* *::* :***:***.*::*****:*:***** ** Mflv_4654|M.gilvum_PYR-GCK DQLNMDRYRDDSGNLRDYVVAARELNPDRLIDNQRDWINRHTVFTHGNGF Mvan_1814|M.vanbaalenii_PYR-1 DQLNMDRYRDEDGNLRDYVVAARELNPDRLIDNQRDWINRHSVYTHGNGF MSMEG_1959|M.smegmatis_MC2_155 DQLSIDRYIGPDGNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGF Mb3215c|M.bovis_AF2122/97 DQLSIDRYLDRNGNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGF Rv3193c|M.tuberculosis_H37Rv DQLSIDRYLDRNGNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGF MMAR_1371|M.marinum_M DQLSIDRYFDRNNNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGF MUL_2505|M.ulcerans_Agy99 DQLSIDRYFDRNNNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGF MAV_4137|M.avium_104 DQLSIDRYLDRNGALRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGF MLBr_00644|M.leprae_Br4923 DQLSIDRYLDKKGNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGF MAB_3498c|M.abscessus_ATCC_199 DALSIDRYQDKNGSLRDYVVAARELDPAKLRDNQRDWINRHTVYTHGNGF * *.:*** . .. ***********:* :* **********:*:****** Mflv_4654|M.gilvum_PYR-GCK IASPANTVRGIANDPNQNGGYPEFLASVVGANGEVSSPGPAPLAQPRIYF Mvan_1814|M.vanbaalenii_PYR-1 IASPANTVRGIANDPNQNGGYPEFLASVVGANGEVVSPGPAPLDQPRIYF MSMEG_1959|M.smegmatis_MC2_155 IASPANTVRGVANDPNQNGGYPEFLASVVGANGSVISPGPAPLDQPRIYF Mb3215c|M.bovis_AF2122/97 IASPANTVRGIANDPNQNGGYPEFLVNVVGANGTVVSDGPAPLDQPRIYF Rv3193c|M.tuberculosis_H37Rv IASPANTVRGIANDPNQNGGYPEFLVNVVGANGTVVSDGPAPLDQPRIYF MMAR_1371|M.marinum_M IASPANTVRGIANDPNQNGGYPEFLVNVVGANGTVVSDGPAPLDQPRIYY MUL_2505|M.ulcerans_Agy99 IASPANTVRGIANDPNQNGGYPEFLVNVVGANGTVVSDGPAPLDQPRIYY MAV_4137|M.avium_104 IASPANTVRGIANDPNQNGGYPEFLVNVVGANGNVVSDGPAPLDQPRVYF MLBr_00644|M.leprae_Br4923 IASPANTVRGIANDPNQNGGYPQFLVNVVG-NGTVVSEGPARLDQPRVYF MAB_3498c|M.abscessus_ATCC_199 IAAPANTVRGVADKPDENGGYPEFLVNAVDDNGKVLSDGPAPLAQPRVYY **:*******:*:.*::*****:**...*. ** * * *** * ***:*: Mflv_4654|M.gilvum_PYR-GCK GPVIASAADDYAIVGESG-TPREYDYETNTDTRNYTYTGSGGVPIGNWLT Mvan_1814|M.vanbaalenii_PYR-1 GPVIANTPADYAIVGESG-TPREYDYETNTATRNYTYTGSGGVPIGNWLT MSMEG_1959|M.smegmatis_MC2_155 GPVISNTPADYAIVGKTGDTDREYDYETNTETKNYTYGGKGGVPIGNWLN Mb3215c|M.bovis_AF2122/97 GPVISNTSADYAIVGRNG-DDREYDYETNIDTKRYTYTGSGGVPLGGWLA Rv3193c|M.tuberculosis_H37Rv GPVISNTSADYAIVGRNG-DDREYDYETNIDTKRYTYTGSGGVPLGGWLA MMAR_1371|M.marinum_M GPVISNTPADYAIVGKTG-ADREYDYETSADTKNYTYTGSGGVSVGSWIS MUL_2505|M.ulcerans_Agy99 GPVISNTPADYAIVGKTG-ADREYDYETSADTKNYTYTGSGGVSVGSWIS MAV_4137|M.avium_104 GPVISNTSADYAIVGRNG-ADREYDYETSTETKNYTYTGLGGVPIGDWLS MLBr_00644|M.leprae_Br4923 GPVISNTSADYAIVGKNG-DDREYDYETNTDTKRYTYAGSGGVPIGSWLS MAB_3498c|M.abscessus_ATCC_199 GPIIASDTNDYAIVGKNG-NDREYDYENNAGTKNSTYTGSGGVPVGGALA **:*:. . ******..* ******.. *:. ** * ***.:*. : Mflv_4654|M.gilvum_PYR-GCK RSVFAAKYAERNFLFSNVINENSKILFNRDPADRVEAVAPWLTTDTTVYP Mvan_1814|M.vanbaalenii_PYR-1 RSVFAAKYAERNFLFSNVIGENSKILFNRDPADRVEAVAPWLTTDTAVYP MSMEG_1959|M.smegmatis_MC2_155 RSVFAAKFAERNFLFSNVIGENSKILFNRDPAERVEAVAPWLTTDTSVYP Mb3215c|M.bovis_AF2122/97 RSVFAAKFAERNFLFSNVIGSNSKILFNRDPAQRVEAVAPWLTTDSAVYP Rv3193c|M.tuberculosis_H37Rv RSVFAAKFAERNFLFSNVIGSNSKILFNRDPAQRVEAVAPWLTTDSAVYP MMAR_1371|M.marinum_M RTVFAAKFAERNFLFSNVIGSNSKILFNRDPAQRVEAVAPWLTTDSAVYP MUL_2505|M.ulcerans_Agy99 RTVFAAKFAERNFLFSNVIGSNSKILFNRDPAQRVEAVAPWLTTDSAVYP MAV_4137|M.avium_104 RSVFAAKFAERNFLFSNVIGSNSKILFNRDPARRVEAVAPWLTTDSSVYP MLBr_00644|M.leprae_Br4923 RSVFAAKFAERNFLFSSVIGSNSKILFNRDPAQRVEAVAPWLTTDSSVYP MAB_3498c|M.abscessus_ATCC_199 RTVFGLKYAERNFLFSNVIGDNSKILFNRDPSRRVEAVAPWLTVDSGTYP *:**. *:********.**..**********: **********.*: .** Mflv_4654|M.gilvum_PYR-GCK AIVNERIVWIVDGYTTLDNYPYSELSTLSSVTTDSNEVAQNRLQLDKQVS Mvan_1814|M.vanbaalenii_PYR-1 AIVNKRIVWIVDGYTTLDNYPYSELMSLSSATTDSNEVALNRLQPDKQVS MSMEG_1959|M.smegmatis_MC2_155 AIVNKRMVWIVDGYTTLDNYPYSELTTLSSATADSNEVAVNRLAPDKKVS Mb3215c|M.bovis_AF2122/97 AIVNKRLVWIVDGYTTLDNYPYSELTSLSSATADSNEVAFNRLVPDKKVS Rv3193c|M.tuberculosis_H37Rv AIVNKRLVWIVDGYTTLDNYPYSELTSLSSATADSNEVAFNRLVPDKKVS MMAR_1371|M.marinum_M AIVNKRMVWILDGYTTLDNYPYSQLTSLSSATADSNEVAFNRLLPDKQVS MUL_2505|M.ulcerans_Agy99 AIVNKRMVWILDGYTTLDNYPYSQLTSLSSATADSNEVAFNRLLPDKQVS MAV_4137|M.avium_104 AIVNKRLVWIIDGYTTLDNYPYSELTSLESATADSNEVAFNKLAPDKRVS MLBr_00644|M.leprae_Br4923 AIVNKRLVWIIDGYTTLDNYPYSERTSLSSATADSTEVAFNRLAPDKRVA MAB_3498c|M.abscessus_ATCC_199 AIVDKRLVWIVDGYTTLDNYPYSQQTSLSEATFDSQVGRTGGALPNQQVS ***::*:***:************: :*...* ** . :::*: Mflv_4654|M.gilvum_PYR-GCK YIRNSVKATVDAYDGTVTLYAQDEQDPVLQAWMKVFPDSVKPKSDITPEL Mvan_1814|M.vanbaalenii_PYR-1 YIRNSVKATVDAYDGTVTLYAQDEQDPVLQAWMKVFPDTVKPKADITPEL MSMEG_1959|M.smegmatis_MC2_155 YIRNSVKATVDAYDGTVTLYAQDENDPVLKAWMDVFPGTVKPKADITPEL Mb3215c|M.bovis_AF2122/97 YIRNSVKATVDAYDGTVTLYQQDEKDPVLKAWMQVFPGTVKPKSDIAPEL Rv3193c|M.tuberculosis_H37Rv YIRNSVKATVDAYDGTVTLYQQDEKDPVLKAWMQVFPGTVKPKSDIAPEL MMAR_1371|M.marinum_M YIRNSVKATVDAYDGTVTLYQQDEQDPVLKAWMQVFPGTVKPKGDISPEL MUL_2505|M.ulcerans_Agy99 YIRNSVKATVDAYDGTVTLYQQDEQDPVLKAWMQVFPGTVKPKGDISPEL MAV_4137|M.avium_104 YIRNSVKATVDAYDGTVTLYQQDEQDPVLKAWMQVFPGTVKPKSDISPEL MLBr_00644|M.leprae_Br4923 YIRNSVKATVDAYDGAVTLYQQDEYDPVLKVWMKVFPGTVRPKGDITPEL MAB_3498c|M.abscessus_ATCC_199 YIRNSVKATVDAYDGTVTLYQQDEKDPVLKAWMKIFPGTVKPKADISDDL ***************:**** *** ****:.**.:**.:*:**.**: :* Mflv_4654|M.gilvum_PYR-GCK QEHLRYPEDLFKVQRALLAKYHVDDPVTFFSTSDFWDVPLDPNPTASSYQ Mvan_1814|M.vanbaalenii_PYR-1 QEHLRYPEDLFKVQRALLAKYHVDDPVTFFSTSDFWDVPLDPNPTASSYQ MSMEG_1959|M.smegmatis_MC2_155 QAHLRYPEDLFKVQRALLAKYHVDNPVTFFSAQDFWDVPLDPNPTASSFQ Mb3215c|M.bovis_AF2122/97 AEHLRYPEDLFKVQRMLLAKYHVNDPVTFFSTSDFWDVPLDPNPTASSYQ Rv3193c|M.tuberculosis_H37Rv AEHLRYPEDLFKVQRMLLAKYHVNDPVTFFSTSDFWDVPLDPNPTASSYQ MMAR_1371|M.marinum_M AAHLRYPEDLFKVQRMLLAKYHVNDPVTFFSTSDFWDVPLDPNPTASSYQ MUL_2505|M.ulcerans_Agy99 AAHLRYPEDLFKVQRMLLAKYHVNDPVTFFSTSDFWDVPLDPNPTASSYQ MAV_4137|M.avium_104 AEHLRYPEDLFKVQRMLLAKYHVNDPVTFFSTSDFWDVPLDPNPTASSYQ MLBr_00644|M.leprae_Br4923 AEHLRYPEDLFKVQRMLLAKYHVNDPGTFFNTSDFWDVPLDPNPTASSYQ MAB_3498c|M.abscessus_ATCC_199 KRHLRYPEDLFKVQRTLLARYHVNDPVTFFSTSDFWQVPDDPNAPTGS-Q ************* ***:***::* ***.:.***:** ***..:.* * Mflv_4654|M.gilvum_PYR-GCK PPYYIVAKDLAENNGSASFQLTSAMNRFRRDFLAAYISASSDPETYGRLT Mvan_1814|M.vanbaalenii_PYR-1 PPYYIVAKDLAENNNSSSFQLTSAMNRFRRDFLAAYISASSDPETYGKLT MSMEG_1959|M.smegmatis_MC2_155 PPYYIVAKDLVKNDNSASFQLTSALNRFQRDFLAAYVSASSDPETYGKLT Mb3215c|M.bovis_AF2122/97 PPYYIVAKNIAKDDNSASYQLISAMNRFKRDYLAAYISASSDPATYGNLT Rv3193c|M.tuberculosis_H37Rv PPYYIVAKNIAKDDNSASYQLISAMNRFKRDYLAAYISASSDPATYGNLT MMAR_1371|M.marinum_M PPYYIVAKNIAKNDNSASYQLISAMNRFKRDYLAAYISASSDPATYGKIT MUL_2505|M.ulcerans_Agy99 PPYYIVAKNIAKNDNSASYQLISAMNRFKRDYLAAYISASSDPATYGKIT MAV_4137|M.avium_104 PPYYIVAKNIAKNDNSSSYQLTSAMNRFKRDYLAAYISASSDPATYGRIT MLBr_00644|M.leprae_Br4923 PPYYIVAKNILKNDRSASYQLTSAMNRFKQDFLAAYISASSDPETYGKIT MAB_3498c|M.abscessus_ATCC_199 PPYYIVAKDITKNDNSASFQLTSALNRFQRDFLAAYVSASSDPETYGKIT ********:: ::: *:*:** **:***::*:****:****** ***.:* Mflv_4654|M.gilvum_PYR-GCK VLTVPGQVNGPKLAFNAISTDTAISTELGQIGRDGQNRIRWGNLLTLPMG Mvan_1814|M.vanbaalenii_PYR-1 VLTIPGQVNGPKLAFNAISTDTAVSQDLGVIGRDNQNRIRWGNLLTLPMG MSMEG_1959|M.smegmatis_MC2_155 VLTIPGQVNGPKLAFNAISTDTAVSQDLGVIGRDNQNRIRWGNLLTLPVA Mb3215c|M.bovis_AF2122/97 VLTIPGQVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVA Rv3193c|M.tuberculosis_H37Rv VLTIPGQVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVA MMAR_1371|M.marinum_M VLTIPGQVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVG MUL_2505|M.ulcerans_Agy99 VLTIPGQVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVG MAV_4137|M.avium_104 VLTIPGQVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVG MLBr_00644|M.leprae_Br4923 VLTIPGNVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVA MAB_3498c|M.abscessus_ATCC_199 VLTVPGTVQGPKLVNNAITTDNQVSSHVGIIK--NQNILKWGNLLTLPVA ***:** *:****. ***:** :* .:* * .** ::********:. Mflv_4654|M.gilvum_PYR-GCK DGGLLYVAPIYASPGNTDAASTYPRLIRVAMMYNDQIGYGPTVRDALTDL Mvan_1814|M.vanbaalenii_PYR-1 QGGLLYVAPVYASPGASDAASSYPRLIRVAMMYNDQIGYGPTVRDALTDL MSMEG_1959|M.smegmatis_MC2_155 DGGLLYVAPVYASPGSSDAASSYPRLIRVAMLYNDRVGYGPTVSDALTEL Mb3215c|M.bovis_AF2122/97 QGGLLYVEPVYASPGASDAASSYPRLIRVAMMYNDKVGYGPTVRDALTGL Rv3193c|M.tuberculosis_H37Rv RGGLLYVEPVYASPGASDAASSYPRLIRVAMMYNDKVGYGPTVRDALTGL MMAR_1371|M.marinum_M QGGLLYVEPVYASPGASDAASSYPRLIRVAMMYNDKIGYGPTVRDALNGL MUL_2505|M.ulcerans_Agy99 QGGLLYVEPVYASPGASDAASSYPRLIRVAMMYNDKIGYGPTVRDALNGL MAV_4137|M.avium_104 QGGLLYVEPVYASPGASDAASSYPRLIRVAMMYNDKIGYGPTVRDALTGL MLBr_00644|M.leprae_Br4923 QGGLLYVEPVYASPGVSDAASSYPRLIRVAMMYNDKIGYGPTVGDALTGL MAB_3498c|M.abscessus_ATCC_199 NGGLLFVEPLYASPGQGDQSS-YPRLIRVGMYYNGKVGYATTVRDALDMV ****:* *:***** * :* *******.* **.::**..** *** : Mflv_4654|M.gilvum_PYR-GCK FGPGADATATGPAATEPPAGQAPQTQGNNTAPPAAQPPNRQGQAPAGR-P Mvan_1814|M.vanbaalenii_PYR-1 FGPGADATATGPAATEPPAGQAPQPQGNN-QPPAAAPPNRPGQAPTPQQP MSMEG_1959|M.smegmatis_MC2_155 FGPGAGATATDVAPAE---GRPAQSTPNGQQPAASPPPAANADGRPAQAP Mb3215c|M.bovis_AF2122/97 FGPGAGATATGIAPTEA--AVPP-SPAANPPPPASGPQP---------PP Rv3193c|M.tuberculosis_H37Rv FGPGAGATATGIAPTEA--AVPP-SPAANPPPPASGPQP---------PP MMAR_1371|M.marinum_M FGPGAGDAATGIQPTEG--GAPANVPPNNAPSPEALPGTPP-------SP MUL_2505|M.ulcerans_Agy99 FGPGAGDAATGIQPTEG--GAPANVPPNNAPSPEALPGTPP-------SP MAV_4137|M.avium_104 FGPGAGAAATNIQPTEG--GAPAASPPANAPAPAVTPGS---------AP MLBr_00644|M.leprae_Br4923 FGPGAASAATGIEPTEA--VPPK--SPAGSSTP----------------P MAB_3498c|M.abscessus_ATCC_199 FGPGAGATATAPAVEPG---AMPPAPPGGQNVP----------------V ***** :** . . Mflv_4654|M.gilvum_PYR-GCK EVPVAVPPTGPTQLSAAKSAALQDVNAALDALRGAQESGDFAQYGEALQR Mvan_1814|M.vanbaalenii_PYR-1 EVPVAVPPTGPTQLSAGKAAALQDVNAALDALQDAQRSGDFAQYGEALQR MSMEG_1959|M.smegmatis_MC2_155 PPPSAATPTGPVQISQAKAEALQDLESALTAAQEAQRSGDFAEYGQALQR Mb3215c|M.bovis_AF2122/97 VTAAPPVPVGAVTLSPAKVAALQEIQAAIGAARDAQKKGDFAAYGSALQR Rv3193c|M.tuberculosis_H37Rv VTAAPPVPVGAVTLSPAKVAALQEIQAAIGAARDAQKKGDFAAYGSALQR MMAR_1371|M.marinum_M PTAVPPAPEASVTLSPAKAAAMKEIQSAIGAARDAQKKGDFAAYGAALQR MUL_2505|M.ulcerans_Agy99 PTAVPPAPEASVTLSPARAAAMKEIQSAIGAARDAQKKGDFAAYGAALQR MAV_4137|M.avium_104 PVAAPPVPDGSVTLSPAKAAVLQEIQAAIGAAKDAQKKGDFAGYGAALQR MLBr_00644|M.leprae_Br4923 IAVVPSAPDGSVALSAAKAAALQEIQAVIGAAREAQKKGDFVAYGSALQR MAB_3498c|M.abscessus_ATCC_199 VPPVTPPPTGSAELSSAKAAALQEVQRAIGEVKEAQKSGDFARYGQALKG . * ... :* .: .::::: .: : **..***. ** **: Mflv_4654|M.gilvum_PYR-GCK LDDAVNKYQETD Mvan_1814|M.vanbaalenii_PYR-1 LDDAVNKYQATN MSMEG_1959|M.smegmatis_MC2_155 LNDAMKKYDSAK Mb3215c|M.bovis_AF2122/97 LDEAITKFNDAG Rv3193c|M.tuberculosis_H37Rv LDEAITKFNDAG MMAR_1371|M.marinum_M LDDAITKFNNTQ MUL_2505|M.ulcerans_Agy99 LDDAITKFNNTQ MAV_4137|M.avium_104 LDDAITKYNNTK MLBr_00644|M.leprae_Br4923 LDDAITKFNSTK MAB_3498c|M.abscessus_ATCC_199 LDDAMTKFTQAR *::*:.*: :