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MKMVKSIAAGLTAAAAIGAAAAGVTSIMAGGPVVYQMQPVVFGAPLPLDPASAPDVPTAAQLTSLLNSLA DPNVSFANKGSLVEGGIGGTEARIADHKLKKAAEHGDLPLSFSVTNIQPAAAGSATADVSVSGPKLSSPV TQNVTFVNQGGWMLSRASAMELLQAAGN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2397c | cfp2 | - | 100% (168) | low molecular weight antigen CFP2 (low molecular weight protein antigen 2) (CFP-2) |
| M. bovis AF2122 / 97 | Mb2140 | lppK | 3e-08 | 29.63% (162) | lipoprotein lppK |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3068 | - | 2e-23 | 42.26% (168) | hypothetical protein Mflv_3068 |
| M. tuberculosis H37Rv | Rv2376c | cfp2 | 3e-90 | 100.00% (168) | low molecular weight antigen CFP2 (low molecular weight |
| M. leprae Br4923 | MLBr_00620 | mtb12 | 4e-55 | 65.45% (165) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_2161c | - | 4e-28 | 42.33% (163) | low molecular weight antigen Mtb12 |
| M. marinum M | MMAR_3688 | cfp2 | 2e-65 | 73.05% (167) | low molecular weight antigen Cfp2 |
| M. avium 104 | MAV_2019 | - | 1e-55 | 65.90% (173) | low molecular weight antigen MTB12 |
| M. smegmatis MC2 155 | MSMEG_3903 | - | 4e-22 | 38.37% (172) | low molecular weight antigen MTB12 |
| M. thermoresistible (build 8) | TH_2667 | - | 9e-36 | 48.52% (169) | PUTATIVE low molecular weight antigen Cfp2 |
| M. ulcerans Agy99 | MUL_2338 | lppK | 4e-08 | 31.71% (164) | lipoprotein, LppK |
| M. vanbaalenii PYR-1 | Mvan_3459 | - | 8e-22 | 41.67% (168) | low molecular weight antigen CFP2 (low molecular weight protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3068|M.gilvum_PYR-GCK MTLKSLVTSLTTGAAAAACVGAAVAGVTSIAAG--AGIASASPVVS-APL
Mvan_3459|M.vanbaalenii_PYR-1 MTLKTLVTSFTAGAAAAATLGAAAVGVTSIAVG--AGTAAASPVAL-APL
MSMEG_3903|M.smegmatis_MC2_155 MTPKSLVTGFITAAAAAAVVSGAAAGVTSIASSGMSTSPAIQPVVFGAPL
Mb2397c|M.bovis_AF2122/97 ---MKMVKSIAAGLTAAAAIGAAAAGVTSIMAG-GPVVYQMQPVVFGAPL
Rv2376c|M.tuberculosis_H37Rv ---MKMVKSIAAGLTAAAAIGAAAAGVTSIMAG-GPVVYQMQPVVFGAPL
MMAR_3688|M.marinum_M ----MTLKSITMGMAAAAAIGAAVTGVTVVTSA-AGASYQVQPVVFGAPL
MLBr_00620|M.leprae_Br4923 ----MTMKSIAT-YAALAIIGAAVDGLTSMAIPTGPAASHIQPVAFGVPL
MAV_2019|M.avium_104 ---MNTVKTIATGVAALAIVGGAAAGLAAAAAP--SAPGTVRLAAVGAPL
TH_2667|M.thermoresistible__bu -VTLNRLKTSLVTGAAAIAFAGAAAGVTTVAAGSLTASPTVQPVVFGTPL
MAB_2161c|M.abscessus_ATCC_199 MTGVAMLGLLAAVAVGSAVPTGEPTASSASPTATTVTSFTIAPASWDVPL
MUL_2338|M.ulcerans_Agy99 -MHRNRRLAITAITAITAVATLGVAGCSPSPDNAESSTSAVAPAPPAAPS
. . : . .*
Mflv_3068|M.gilvum_PYR-GCK PAAPAPDL---------AGPLVSTLSALSGPGSFGGNKASYVQGGLGRIE
Mvan_3459|M.vanbaalenii_PYR-1 PAAPAPEL---------QGALVSTLSALSGPGSFAGGKASYVQGGLGRIE
MSMEG_3903|M.smegmatis_MC2_155 PQQPAPEL---------EAPLIQTLQALASGGSFSG-KAPYIQGGIGRVE
Mb2397c|M.bovis_AF2122/97 PLDPASAP-----DVPTAAQLTSLLNSLADPNVSFANKGSLVEGGIGGTE
Rv2376c|M.tuberculosis_H37Rv PLDPASAP-----DVPTAAQLTSLLNSLADPNVSFANKGSLVEGGIGGTE
MMAR_3688|M.marinum_M PQDPAPAPAT---DVPTAAELTGLLNSLVDPNVSFTSKSGLVEGGIGGTE
MLBr_00620|M.leprae_Br4923 PQDPAPAA-----DVPTAAELTSLLNKIVDPDVSFMHKSQLVEGGIGSAE
MAV_2019|M.avium_104 PQDPPPAQPVAGANVPTSDQLTGLLNSLADPSVPFANKSNLVQGGISGVE
TH_2667|M.thermoresistible__bu PEQPAPRQP--AVDAPTADQVYAVLNGLGNPNVPFREKADLIEGGVGIVE
MAB_2161c|M.abscessus_ATCC_199 DVPAEPAD-----GTPTPDELSGLLYSLADPGVSALAKGGLVEGGIGAGE
MUL_2338|M.ulcerans_Agy99 ALPVPPSAP-----LPPPEALVDVLSRLADPNIPGDKKLDLVEG-STPDT
. : * : . . * ::*
Mflv_3068|M.gilvum_PYR-GCK ARVADSGYANAAAKGYFPLNFTVADIDQNGP----VVTANVTAA-AASGA
Mvan_3459|M.vanbaalenii_PYR-1 ARVADSGYNNAAAKGYFPLSFTVADIDQNGP----VVTANVTAA-APTGA
MSMEG_3903|M.smegmatis_MC2_155 SIAADRAYNRAAADGKFPLTFTVNNVDQQGP----VAYADVTAT-AATGG
Mb2397c|M.bovis_AF2122/97 ARIADHKLKKAAEHGDLPLSFSVTNIQPAAAG---SATADVSVSGPKLSS
Rv2376c|M.tuberculosis_H37Rv ARIADHKLKKAAEHGDLPLSFSVTNIQPAAAG---SATADVSVSGPKLSS
MMAR_3688|M.marinum_M ARLADHELKKAAKNGDLPLSFTVANIAPAAAG---AATADVSVSGPKFTA
MLBr_00620|M.leprae_Br4923 AHIGDRELKNAAQKGELPLLFSVTNIRPGTSG---SATADVSVSGPKLNP
MAV_2019|M.avium_104 AHVADKKLQKAAKNGDLPLSFDVTNIQPTASG---AATADVSVSGPKLTS
TH_2667|M.thermoresistible__bu GRTADRLVQSAVEKGYFPLSFRVSEIVPVGPG---LAAATVTASGPNLT-
MAB_2161c|M.abscessus_ATCC_199 AIYADRAFKNANRDGFLPLAFTVSNVKSTGPG---LAAAAVTITGPKTQA
MUL_2338|M.ulcerans_Agy99 AAALDRFTTAARDGGYLPMNFAANDLAWSATNPCDVVATVVVTTAQPENR
. * * * :*: * . :: . . : * :
Mflv_3068|M.gilvum_PYR-GCK VATQPLTFIAGPSPTGWQLSKQSAMALMSAVG------------------
Mvan_3459|M.vanbaalenii_PYR-1 VATQPLTFIAGPSPTGWQLSKQSAMALMSAVG------------------
MSMEG_3903|M.smegmatis_MC2_155 TATQNIQFVAGPSPTGWQISKGSALSLLSSVG------------------
Mb2397c|M.bovis_AF2122/97 PVTQNVTFVN---QGGWMLSRASAMELLQAAGN-----------------
Rv2376c|M.tuberculosis_H37Rv PVTQNVTFVN---QGGWMLSRASAMELLQAAGN-----------------
MMAR_3688|M.marinum_M PITQNVTFVN---QGSWVLSRSSAMQLLQAAGH-----------------
MLBr_00620|M.leprae_Br4923 PVTQNITFIN---KGSWVLSRHSAMELLQAAGR-----------------
MAV_2019|M.avium_104 PVTQNVTFVN---QGGWVLSRASAMELLQAAGQ-----------------
TH_2667|M.thermoresistible__bu PTTERITLVN---DGGWKLSRASGLALLQSALS-----------------
MAB_2161c|M.abscessus_ATCC_199 YTTN-INFVD---QDGWKISKASAISLIQAASGKSGR-------------
MUL_2338|M.ulcerans_Agy99 EFTVPMEFTP--IHGGWQLSQRTSEMLLAPGNSRGSQTATPEPSPGPAPN
* : : .* :*: :. *: .
Mflv_3068|M.gilvum_PYR-GCK ----------------------------
Mvan_3459|M.vanbaalenii_PYR-1 ----------------------------
MSMEG_3903|M.smegmatis_MC2_155 ----------------------------
Mb2397c|M.bovis_AF2122/97 ----------------------------
Rv2376c|M.tuberculosis_H37Rv ----------------------------
MMAR_3688|M.marinum_M ----------------------------
MLBr_00620|M.leprae_Br4923 ----------------------------
MAV_2019|M.avium_104 ----------------------------
TH_2667|M.thermoresistible__bu ----------------------------
MAB_2161c|M.abscessus_ATCC_199 ----------------------------
MUL_2338|M.ulcerans_Agy99 PEPAPVEPAPEESPPATGSVAPSSGPPG