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M. bovis AF2122 / 97 Mb2378c (glyS)

annotation: glycyl-tRNA synthetase
coordinates: 2607744 - 2609135
length: 463

VHHPVAPVIDTVVNLAKRRGFVYPSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVVTGRDDVVGIDSS
IILPREVWVASGHVDVFHDPLVESLITHKRYRADHLIEAYEAKHGHPPPNGLADIRDPETGEPGQWTQPR
EFNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQIGKSFRNEITPGNFIFRTR
EFEQMEMEFFVEPATAKEWHQYWIDNRLQWYIDLGIRRENLRLWEHPKDKLSHYSDRTVDIEYKFGFMGN
PWGELEGVANRTDFDLSTHARHSGVDLSFYDQINDVRYTPYVIEPAAGLTRSFMAFLIDAYTEDEAPNTK
GGMDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLGAELRKCWNIDFDDAGAIGRRYRRQDEVGTPF
CVTVDFDSLQDNAVTVRERDAMTQDRVAMSSVADYLAVRLKGS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2378cglyS-100% (463)glycyl-tRNA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2719-0.080.26% (466) glycyl-tRNA synthetase
M. tuberculosis H37RvRv2357cglyS0.0100.00% (463) glycyl-tRNA synthetase
M. leprae Br4923MLBr_00826glyS0.090.20% (459) glycyl-tRNA synthetase
M. abscessus ATCC 19977MAB_1702-0.080.00% (460) glycyl-tRNA synthetase
M. marinum MMMAR_3667glyS0.092.16% (459) glycyl-tRNA synthetase GlyS
M. avium 104MAV_2038glyS0.089.74% (458) glycyl-tRNA synthetase
M. smegmatis MC2 155MSMEG_4485glyS0.083.30% (461) glycyl-tRNA synthetase
M. thermoresistible (build 8)TH_0836glyS0.080.87% (460) PROBABLE GLYCYL-tRNA SYNTHETASE GLYS (GLYCINE--tRNA LIGASE)
M. ulcerans Agy99MUL_3610glyS0.091.92% (458) glycyl-tRNA synthetase
M. vanbaalenii PYR-1Mvan_3818-0.081.76% (466) glycyl-tRNA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2719|M.gilvum_PYR-GCK          ----MAP-SSIIDTVANLAKRRGLVFQSGEIYGGTKSAWDYGPLGVELKE
Mvan_3818|M.vanbaalenii_PYR-1       ----MAPSSSIIDTVANLAKRRGLVFQSGEIYGGTKSAWDYGPLGVELKE
MSMEG_4485|M.smegmatis_MC2_155      ----MAS---IIDTVANLAKRRGLVYQSGEIYGGTKSAWDYGPLGVELKE
TH_0836|M.thermoresistible__bu      ----VAS---IIDTVANLAKRRGFVYQSGEIYGGTRSAWDYGPLGVELKE
Mb2378c|M.bovis_AF2122/97           MHHPVAP---VIDTVVNLAKRRGFVYPSGEIYGGTKSAWDYGPLGVELKE
Rv2357c|M.tuberculosis_H37Rv        MHHPVAP---VIDTVVNLAKRRGFVYPSGEIYGGTKSAWDYGPLGVELKE
MLBr_00826|M.leprae_Br4923          MPCLVAS---VIDTVVNLAKRRGFVYPAGEIYGGTKSAWDYGPLGVEFKE
MAV_2038|M.avium_104                ----MAS---VIDTVVNLAKRRGFVYPSGEIYGGTRSAWDYGPLGVEFKE
MMAR_3667|M.marinum_M               MGCPVAS---VIDTVVNLAKRRGLVYPSGEIYGGTKSAWDYGPLGVELKE
MUL_3610|M.ulcerans_Agy99           ----MAS---VIDTVVNLAKRRGLVYPSGEIYGGTKSAWDYGPLGVELKE
MAB_1702|M.abscessus_ATCC_1997      MAAKPNAAGKKIEAVVNLAKRRGLVYPCGEIYGGTKSAWDYGPLGVELKE
                                          .    *::*.*******:*: .*******:***********:**

Mflv_2719|M.gilvum_PYR-GCK          NIKKQWWRSVITSRDDVVGLDSAIILPRQVWVASGHVEVFNDPLVECLNC
Mvan_3818|M.vanbaalenii_PYR-1       NIKRQWWRAVVTSRDDVVGLDSAIILPREVWVASGHVEVFNDPLVECLNC
MSMEG_4485|M.smegmatis_MC2_155      NIKRQWWKSVVTGRDDVVGLDSAIILPRQVWVASGHVEVFNDPLVECLSC
TH_0836|M.thermoresistible__bu      NIKRQWWKSMVTAREDVVGIDTSIILPREVWVASGHVDVFHDPLVECLNC
Mb2378c|M.bovis_AF2122/97           NIKRQWWRSVVTGRDDVVGIDSSIILPREVWVASGHVDVFHDPLVESLIT
Rv2357c|M.tuberculosis_H37Rv        NIKRQWWRSVVTGRDDVVGIDSSIILPREVWVASGHVDVFHDPLVESLIT
MLBr_00826|M.leprae_Br4923          NIKRQWWRSVVTGREDVVGIDSSIILPRQVWVASGHLEIFHDPLVESLIT
MAV_2038|M.avium_104                NIKRQWWRSVVTAREDVVGLDSSIILPRQVWVASGHVEVFHDPLVESLIT
MMAR_3667|M.marinum_M               NIKRQWWRSVVTGRDDVVGLDSSIILPREVWVASGHVEVFHDPLVESLIT
MUL_3610|M.ulcerans_Agy99           NIKRQWWRSVVTGREDVVGLDSSIILPREVWVASGHVEVFHDPLVESLIT
MAB_1702|M.abscessus_ATCC_1997      NIKKQWWRSVVTSRDDVVGLDSSVILPRQVWVASGHVEVFNDPLVECLNC
                                    ***:***::::*.*:****:*:::****:*******:::*:*****.*  

Mflv_2719|M.gilvum_PYR-GCK          HKRHRQDHMQEAFFEKGGEKKGFSSPDEVPMGEIVCPDCGTKGQWTEPRD
Mvan_3818|M.vanbaalenii_PYR-1       HKRHRQDHMQEAYAEKEAKKGVTVDPDAVAMTEIVCPDCGTKGQWTEPRD
MSMEG_4485|M.smegmatis_MC2_155      HKRHRQDHMQEAYAEK----KGIDDPDSVPMSEISCPDCGTKGQWTEPRD
TH_0836|M.thermoresistible__bu      HRRHRQDHLQEALAGK----KGLDNPDDVPMDEVVCPDCGTKGRWTEPRE
Mb2378c|M.bovis_AF2122/97           HKRYRADHLIEAYEAKHG------HPPPNGLADIRDPETGEPGQWTQPRE
Rv2357c|M.tuberculosis_H37Rv        HKRYRADHLIEAYEAKHG------HPPPNGLADIRDPETGEPGQWTQPRE
MLBr_00826|M.leprae_Br4923          HKRYRADHLIEAYEAKHG------QSPCNGLADIRDPDTGEPGQWTEPRE
MAV_2038|M.avium_104                HKRYRADHLIEAYEAKHG------HPPPNGLADIRDPDTGEPGRWTEPRE
MMAR_3667|M.marinum_M               HKRYRADHLIEAYEAKHG------QPPPNGLADIRDPETGEPGQWTEPRE
MUL_3610|M.ulcerans_Agy99           HKRYRADHLIEAYEAKHG------QPPPNGLADIRDPETGEPGQWTEPRE
MAB_1702|M.abscessus_ATCC_1997      HKRHRQDHLQEAYSEKEAKKGLTIAPESVPMTEIVCPDCGNKGQWTEPRD
                                    *:*:* **: **   *         .    : ::  *: *  *:**:**:

Mflv_2719|M.gilvum_PYR-GCK          FNMMLKTYLGPIESEEGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQ
Mvan_3818|M.vanbaalenii_PYR-1       FNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQ
MSMEG_4485|M.smegmatis_MC2_155      FNMMLKTYLGPIESEDGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQ
TH_0836|M.thermoresistible__bu      FNMMLKTYLGPIESDEGLHYLRPETAQGIFTNFANVVTTARKKPPFGIAQ
Mb2378c|M.bovis_AF2122/97           FNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQ
Rv2357c|M.tuberculosis_H37Rv        FNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQ
MLBr_00826|M.leprae_Br4923          FNLMLKTYLGPIETEEGLHYLRPETAQGIFINFANVVTTARRKPPFGIGQ
MAV_2038|M.avium_104                FNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQ
MMAR_3667|M.marinum_M               FNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFANVLTTSRKKPPFGIGQ
MUL_3610|M.ulcerans_Agy99           FNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFANVLTTSRKKPPFGIGQ
MAB_1702|M.abscessus_ATCC_1997      FNMMLKTYLGPIETEEGLHYLRPETAQGIFINFKNVVTTSRQKPPFGIGQ
                                    **:**********:::************** ** **:**:*:******.*

Mflv_2719|M.gilvum_PYR-GCK          IGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAAEWHKYWIETRLQWY
Mvan_3818|M.vanbaalenii_PYR-1       IGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAAEWHRYWIETRLQWY
MSMEG_4485|M.smegmatis_MC2_155      IGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAAEWHQYWIDTRLQWY
TH_0836|M.thermoresistible__bu      TGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDTRLQWY
Mb2378c|M.bovis_AF2122/97           IGKSFRNEITPGNFIFRTREFEQMEMEFFVEPATAKEWHQYWIDNRLQWY
Rv2357c|M.tuberculosis_H37Rv        IGKSFRNEITPGNFIFRTREFEQMEMEFFVEPATAKEWHQYWIDNRLQWY
MLBr_00826|M.leprae_Br4923          IGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTARDWHQYWIDTRMQWY
MAV_2038|M.avium_104                IGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDTRLQWY
MMAR_3667|M.marinum_M               IGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDTRLQWY
MUL_3610|M.ulcerans_Agy99           IGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDTRLQWY
MAB_1702|M.abscessus_ATCC_1997      IGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAPEWHKYWIDTRLQWY
                                     *******************************:** :**:***:.*:***

Mflv_2719|M.gilvum_PYR-GCK          VDLGIERDNLRLYEHPKEKLSHYSDGTTDIEYKFGFAGNPWGELEGIANR
Mvan_3818|M.vanbaalenii_PYR-1       VDLGINRDNLRLYEHPKEKLSHYSDGTTDIEYKFGFAGNPWGELEGIANR
MSMEG_4485|M.smegmatis_MC2_155      VDLGIDRDNLRLYEHPKEKLSHYSDRTVDIEYKFGFQGNPWGELEGVANR
TH_0836|M.thermoresistible__bu      VDLGIDRDNLRLYEHPPEKLSHYAERTVDIEYKYGFAGDPWGELEGIANR
Mb2378c|M.bovis_AF2122/97           IDLGIRRENLRLWEHPKDKLSHYSDRTVDIEYKFGFMGNPWGELEGVANR
Rv2357c|M.tuberculosis_H37Rv        IDLGIRRENLRLWEHPKDKLSHYSDRTVDIEYKFGFMGNPWGELEGVANR
MLBr_00826|M.leprae_Br4923          VELGIDPQNLRLFEHPKDKLSHYSDRTVDIEYKFGFVGNPWGELEGVANR
MAV_2038|M.avium_104                VELGIDPQNLRLFEHPADKLSHYSDRTVDIEYKFGFAGNPWGELEGVANR
MMAR_3667|M.marinum_M               VDLGIDAENLRLFEHPKEKLSHYSDRTVDIEYKFGFVGNPWGELEGVANR
MUL_3610|M.ulcerans_Agy99           VDLGIDAENLRLFEHPKEKLSHYSDRTVDIEYKFGFVGNPWGELEGVANR
MAB_1702|M.abscessus_ATCC_1997      VDLGIDPENLRLYDHPKEKLSHYSDGTVDIEYKFGFSGNPWGELEGIANR
                                    ::***  :****::** :*****:: *.*****:** *:*******:***

Mflv_2719|M.gilvum_PYR-GCK          TNFDLSTHSQHSGVDLSFYDQAADTRYVPYVIEPAAGLTRSLMAFLVDAY
Mvan_3818|M.vanbaalenii_PYR-1       TNFDLSTHSKHSGVDLSFYDQANDTRYVPYVIEPAAGLTRSLMAFLVDAY
MSMEG_4485|M.smegmatis_MC2_155      TNFDLSTHAKHSGVDLSFYDQAADTRYVPYVIEPAAGLTRSLMAFLVDAY
TH_0836|M.thermoresistible__bu      TDFDLSTHSKHSGVDLSYYDQATDTRYVPYVIEPAAGLTRSLMAFLIDAY
Mb2378c|M.bovis_AF2122/97           TDFDLSTHARHSGVDLSFYDQINDVRYTPYVIEPAAGLTRSFMAFLIDAY
Rv2357c|M.tuberculosis_H37Rv        TDFDLSTHARHSGVDLSFYDQINDVRYTPYVIEPAAGLTRSFMAFLIDAY
MLBr_00826|M.leprae_Br4923          TDFDLSTHARYSGVDLSFYDQVNDTRYTPYVIEPAAGLTRSFMAFLIDAY
MAV_2038|M.avium_104                TDFDLSTHSKHSGVDLSFYDQATDSRYIPYVIEPAAGLTRSFMAFLIDAY
MMAR_3667|M.marinum_M               TDFDLSTHSKHSGTELSFYDQVEDVRYTPYVIEPAAGLTRSFMAFLIDAY
MUL_3610|M.ulcerans_Agy99           TDFDLSTHSKHSGTELSFYDQVEDVRYTPYVIEPAAGLTRSFMAFLIDAY
MAB_1702|M.abscessus_ATCC_1997      TDFDLSTHAKHSGEDLSYYDQAEDRRYTPYVIEPAAGLTRSFMAFLVDAY
                                    *:******:::** :**:***  * ** *************:****:***

Mflv_2719|M.gilvum_PYR-GCK          TEDEAPNAKGGVDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLAAE
Mvan_3818|M.vanbaalenii_PYR-1       TEDEAPNAKGGVDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLAAE
MSMEG_4485|M.smegmatis_MC2_155      TEDEAPNAKGGVDKRTVLKLDPRLAPVKAAVLPLSRHADLSPKARDLAAE
TH_0836|M.thermoresistible__bu      SEDEAPNAKGGVDKRTVLRFDPRLAPVKVAVLPLSRHADLSPKARDLAAE
Mb2378c|M.bovis_AF2122/97           TEDEAPNTKGGMDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLGAE
Rv2357c|M.tuberculosis_H37Rv        TEDEAPNTKGGMDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLGAE
MLBr_00826|M.leprae_Br4923          TEDEAPNTRGGMDKRALLRLDPRLAPIKAAVLPLFRHVDLSPKARDLAAE
MAV_2038|M.avium_104                VEDEAPNAKGKMEKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLAAE
MMAR_3667|M.marinum_M               TEDEAPNAKGGVDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLAAE
MUL_3610|M.ulcerans_Agy99           TEDEAPNAKGGVDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLAAE
MAB_1702|M.abscessus_ATCC_1997      HEDEAPNAKGGVDTRTVLRLDPRLAPVKVAVLPLSRNADLSPRAKALAAE
                                     ******::* ::.*::*::******:*.***** *:.****:*: *.**

Mflv_2719|M.gilvum_PYR-GCK          LRQSWNVEFDDAGAIGRRYRRQDEIGTPYCITVDFDSLEDHAVTIRERDA
Mvan_3818|M.vanbaalenii_PYR-1       LRQSWNVEFDDAGAIGRRYRRQDEIGTPYCITFDFDSLEDHAVTIRERDA
MSMEG_4485|M.smegmatis_MC2_155      LRRNWNVEFDDAGAIGRRYRRQDEIGTPYCVTVDFDSLEDNAVTIRERDA
TH_0836|M.thermoresistible__bu      LRQHWNVEFDDAGAIGRRYRRQDEVGTPYCVTVDFDSLEDNAVTVRERDS
Mb2378c|M.bovis_AF2122/97           LRKCWNIDFDDAGAIGRRYRRQDEVGTPFCVTVDFDSLQDNAVTVRERDA
Rv2357c|M.tuberculosis_H37Rv        LRKCWNIDFDDAGAIGRRYRRQDEVGTPFCVTVDFDSLQDNAVTVRERDA
MLBr_00826|M.leprae_Br4923          LRKCWNSEFDDAGAIGRRYRRQDEVGTPFCVTVDFESLDDNAVTVRERDA
MAV_2038|M.avium_104                LRRFWNIEFDDAGAIGRRYRRQDEIGTPFCVTVDFDSLEDNAVTVRRRDD
MMAR_3667|M.marinum_M               LRKYWNIDFDDAGAIGRRYRRQDEIGTPFCVTVDFDSLEDDAVTVRERDA
MUL_3610|M.ulcerans_Agy99           LRKYWNIDFDDAGAIGRRYRRQDEIGTPFCVTVDFDSLEDDAVTVRERDA
MAB_1702|M.abscessus_ATCC_1997      LRQSWNVDFDDAGAIGRRYRRQDEIGTPFCVTVDFDSLEDDSVTVRDRDE
                                    **: ** :****************:***:*:*.**:**:*.:**:* ** 

Mflv_2719|M.gilvum_PYR-GCK          MSQERIAISEVSNYLAVRLKGC
Mvan_3818|M.vanbaalenii_PYR-1       MTQERVAISEVSNYLAVRLKGS
MSMEG_4485|M.smegmatis_MC2_155      MTQERIAIDKVSDYLAVRLKGA
TH_0836|M.thermoresistible__bu      MAQERISIDQVTDYLAVRLKGC
Mb2378c|M.bovis_AF2122/97           MTQDRVAMSSVADYLAVRLKGS
Rv2357c|M.tuberculosis_H37Rv        MTQDRVAMSSVADYLAVRLKGS
MLBr_00826|M.leprae_Br4923          MTQERVAMTNVADYLAVRLKGS
MAV_2038|M.avium_104                MSQERIGMDAVADYLSARLKGC
MMAR_3667|M.marinum_M               MTQERIGIAKVADYLAPRLKGC
MUL_3610|M.ulcerans_Agy99           MTQERIGIAKVADYLAPRLKGC
MAB_1702|M.abscessus_ATCC_1997      MTQQRIPIGGVADHLAKTLKGC
                                    *:*:*: :  *:::*:  ***.