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M. bovis AF2122 / 97 Mb2162 (lppL)

annotation: lipoprotein LppL
coordinates: 2377728 - 2378804
length: 358

LLTGNKPAVQRRFIGLLMLSVLVAGCSSNPLANFAPGYPPTIEPAQPAVSPPTSQDPAGAVRPLSGHPRA
ALFDNGTRQLVALRPGADSAAPASIMVFDDVHVAPRVIFLPGPAAALTSDDHGTAFLAARGGYFVADLSS
GHTARVNVADAAHTDFTAIARRSDGKLVLGSADGAVYTLAKNPAVDPASGAATVASRTKIFARVDALVTQ
GNTTVVLDRGQTSVTTIGADGHAQQALRAGQGATTMAADPLGRVLIADTRGGQLLVYGVDPLILRQAYPV
RQAPYGLAGSRELAWVSQTASNTVIGYDLTTGIPVEKVRYPTVQQPNSLAFDETSDTLYVVSGSGAGSRF
IEHAAGTR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2162lppL-100% (358)lipoprotein LppL

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3041-8e-9858.94% (341) putative lipoprotein
M. tuberculosis H37RvRv2138lppL0.099.16% (358) lipoprotein LppL
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2106c-5e-7850.15% (327) lipoprotein LppL
M. marinum MMMAR_3118lppL1e-13469.64% (359) lipoprotein LppL
M. avium 104MAV_2355-1e-13371.68% (346) LppL protein
M. smegmatis MC2 155MSMEG_4196-9e-9659.05% (337) LppL protein
M. thermoresistible (build 8)TH_2366lppL2e-9153.37% (356) Probable conserved lipoprotein LppL
M. ulcerans Agy99MUL_2368lppL1e-13569.64% (359) lipoprotein LppL
M. vanbaalenii PYR-1Mvan_3485-1e-10057.34% (354) SMP-30/gluconolaconase/LRE domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2162|M.bovis_AF2122/97            ----------------MLTGNKPAVQRRFIG---LLMLSVLVAGCSSNPL
Rv2138|M.tuberculosis_H37Rv         ----------------MLTGNKPAVQRRFIG---LLMLSVLVAGCSSNPL
MMAR_3118|M.marinum_M               ----------------MLRNHRKPLQRYFYAPVILLTLLALLTGCSSGPL
MUL_2368|M.ulcerans_Agy99           ----------------MLRNHRKPLQRYFYAPVILLTLLTLLTGCSSGPL
MAV_2355|M.avium_104                ----------------------------------------MLSGCSSNPL
Mflv_3041|M.gilvum_PYR-GCK          ----------------------------------------MISGCSSNPV
Mvan_3485|M.vanbaalenii_PYR-1       ----------------MSRHINPQAQLTRLG--IAALALTLVAGCSSNPV
MSMEG_4196|M.smegmatis_MC2_155      ----------------MLRPITAGQP---LYAAVVSLALLLAAGCSSNVV
TH_2366|M.thermoresistible__bu      -----------------LRPRSNPSARLIRLGAALAAVPLLLSCSGGNPV
MAB_2106c|M.abscessus_ATCC_199      MGNPSSIAMMDAMNRLPRRGMRGIRGTVAALAVVITAAAAASSGCSSGGD
                                                                              : ....  

Mb2162|M.bovis_AF2122/97            ANFAPGYPPTIEPAQPAVSPPTSQDPAGAVRPLSGHPRAALFDNGTRQLV
Rv2138|M.tuberculosis_H37Rv         ANFAPGYPPTIEPAQPAVSPPTSQDPAGAVRPLSGHPRAALFDNGTRQLV
MMAR_3118|M.marinum_M               Q----SAPPTIEPARPAVSPPISQPPAGVVRPLGGHPQAAVYDVDSGRLA
MUL_2368|M.ulcerans_Agy99           Q----SVPPTIEPARPAVSPPISQPPAGVVRPLGGHPQAAVYDVDSGRLA
MAV_2355|M.avium_104                R----GAPPTIEPAGAAVSPPSAQQPAGSVRPLAAHAAAAVFDAGTHQLA
Mflv_3041|M.gilvum_PYR-GCK          D----APPPTIPAAQPAESPVPTARPAGDVQPLAAPVAAAVFDRATKSLL
Mvan_3485|M.vanbaalenii_PYR-1       D----APPPTIEPARAADSPPVTAAPPGVVWPMAGAALAAVFDAATASLL
MSMEG_4196|M.smegmatis_MC2_155      D----APPPTIEPAQAAVSPPVTQQPDGQVRPLASPGQAAVFDPATRQLA
TH_2366|M.thermoresistible__bu      D----RGPATVAPATPAASPPVTGDPAGTVRALDLSARAALFDPGTDTLV
MAB_2106c|M.abscessus_ATCC_199      SE-NSADPRVITPASAAQSPPVTTAPAGTVHRIAGQASAVLFDTSTKTVS
                                           * .: .* .* **  :  * * *  :     *.::*  :  : 

Mb2162|M.bovis_AF2122/97            ALRPGADSAAPASIMVFDDVHVAPRVIFLPGPAAALTSDDHGTAFLAARG
Rv2138|M.tuberculosis_H37Rv         ALRPGADSAAPASIMVFDDVHVAPRVIFLPGPAAALTSDDHGTAFLAARG
MMAR_3118|M.marinum_M               VLSPGSDASAPASISVFTQEQTPARPITLPGPATGLTGDGHGKAYASARG
MUL_2368|M.ulcerans_Agy99           VLSPGSDASAPASISVFAQEQTPARPITLPGPATGLTGDGHGKAYASARG
MAV_2355|M.avium_104                VLAAASD---PASVTLFGDPQVPPRVAALPGPATALTGDGRGTVYLATRG
Mflv_3041|M.gilvum_PYR-GCK          TLCPGPVGR--STVTVFGTS-GPPRPIELDTAATAMVTDGAGAAYLARRG
Mvan_3485|M.vanbaalenii_PYR-1       VLSPGPDG---SAVTVVAES-GAQRPVELADPATAIAGDDDGWAYLSTRG
MSMEG_4196|M.smegmatis_MC2_155      VLSTDAEGQ--SAVALLGQDSRPPVTVPLGANAAALAGDGKGGLLLSTRG
TH_2366|M.thermoresistible__bu      VLG-----TVPAVALLPSTPGVAPRTVALPAEATAICGDGAGTVYLATRG
MAB_2106c|M.abscessus_ATCC_199      ILADEGQ---IVTTVTRDDLDTVRRVTRLPSPATAAVGDDRGTVYLSTAG
                                     *                          *   *:.   *. *    :  *

Mb2162|M.bovis_AF2122/97            GYFVADLS--SGH--TARVNVADAAHTDFTAIARRSDGKLVLGSADGAVY
Rv2138|M.tuberculosis_H37Rv         GYFVADLS--SGH--TARVNVADAAHTDFTAIARRSDGKLVLGSADGAVY
MMAR_3118|M.marinum_M               GYFVVDLP--SGG--ISQVSVADSAGTEFTAIARRMDGKLVLGTADGALY
MUL_2368|M.ulcerans_Agy99           GYFVVDLP--SGG--VSQVNVSDSADTEFTAIARRMDGKLVLGTADGALY
MAV_2355|M.avium_104                GYFVLDLG--TGR--VVRVGVADAAQTEFTAVAQRADGALVLGSADGAVY
Mflv_3041|M.gilvum_PYR-GCK          GYLRLDIA--SGE--VTSRAVDGQDDVDFTAIARRADGRLVLGSADGAVS
Mvan_3485|M.vanbaalenii_PYR-1       GYYRLDIA--TAD--VTKVEVEGREGVDFTAIARRGDGRLVLGSADGTVY
MSMEG_4196|M.smegmatis_MC2_155      GYFRVDLT--AATPAPARVDVDGKGDVDFTAIAVREDGRVVLGSADGAVY
TH_2366|M.thermoresistible__bu      GYLRMNLSGPAEQVAAEKVEVDGHQDTEFTAIARHDDGRLVLGSADGGVY
MAB_2106c|M.abscessus_ATCC_199      GYFALDIA--SGR--ADKVNISGHENTEFSAITRRPDGRIVLGSADGTVF
                                    **   ::   :         : .   .:*:*:: : ** :***:*** : 

Mb2162|M.bovis_AF2122/97            TLAKNPAVDPASG---------AATVASRTKIFARVDALVTQGNTTVVLD
Rv2138|M.tuberculosis_H37Rv         TLAKNPAVDPASG---------AATVASRTKIFARVDALVTQGNTTVVLD
MMAR_3118|M.marinum_M               TLAS-PQTHASAG---------TAQVLSRIKIFARVDAVVTQGNTAVVLD
MUL_2368|M.ulcerans_Agy99           TLAS-PQTPASAG---------TAQVLSRIKIFARVDAVVTQGNTAVVLD
MAV_2355|M.avium_104                TLASPTPAVPTTGPTTRSITGSTAAVANRSKIFARVDSLATQGNTTVVLD
Mflv_3041|M.gilvum_PYR-GCK          TLSS------------------DTAVGARLKIFARVDALATQGDTAVVLD
Mvan_3485|M.vanbaalenii_PYR-1       TLTS------------------ENTVGAQLKTFARVDALVTQGDTAVVLD
MSMEG_4196|M.smegmatis_MC2_155      TLTG------------------DGGVDAELKIFARVDSLVTQGNTAIVLD
TH_2366|M.thermoresistible__bu      TLDS------------------DTTVGGEVTSFVRVDALVTQGGDTVVLD
MAB_2106c|M.abscessus_ATCC_199      TLDL------------------QNQVIAHAAGFAHIDSLAYQGNTVAVLD
                                    **                       *  .   *.::*::. **. . ***

Mb2162|M.bovis_AF2122/97            RGQTSVTTIGADG-HAQQALRAGQGATTMAADPLGRVLIADTRGGQLLVY
Rv2138|M.tuberculosis_H37Rv         RGQTSVTTIGADG-HAQQALRAGQGATTMAADPLGRVLIADTRGGQLLVY
MMAR_3118|M.marinum_M               RGQTSVTTIDADG-RAEQALRAGDGATTMAADSLGRVLVADTRGGQLLVY
MUL_2368|M.ulcerans_Agy99           RGQTSVTTIDADG-RAEQALRAGEGATTMAADSLGRVLVADTRGGQLLVY
MAV_2355|M.avium_104                RGQTSVTTIGADG-RAQQALRAGRGATTMAADAAGRVLVADTRGGQLLVY
Mflv_3041|M.gilvum_PYR-GCK          RGQTSVTTLNSDGTGAAHALRAGEGATTLVADGAHRVLVTDTRGGELLVY
Mvan_3485|M.vanbaalenii_PYR-1       RGQTSVTSLNADGTKSEHALRAGEGATMMAADGAGRVLVTDTRGGELLVY
MSMEG_4196|M.smegmatis_MC2_155      RGQTSVTTVDPSGTKAAHALRAGEGATTIATDPRGLLLVADTRGDGLLVY
TH_2366|M.thermoresistible__bu      RAQSLVTTVDNSGRNPRHALRAGDGATTLATDPAGRVLVADTRGGELLVF
MAB_2106c|M.abscessus_ATCC_199      RAQSSVTTLTAAGDGTAHALRAGEGATTMLADDKGRLLVADTRGGALLAF
                                    *.*: **::   *  . :***** *** : :*    :*::****. **.:

Mb2162|M.bovis_AF2122/97            G-VDPLILRQAYPVRQAPYGLAGSRE---LAWVSQTASNTVIGYDLTTGI
Rv2138|M.tuberculosis_H37Rv         G-VDPLILRQAYPVRQAPYGLAGSRE---LAWVSQTASNTVIGYDLTTGI
MMAR_3118|M.marinum_M               G-VDPLILRQAYPVPQDPYGLAGSNQ---LAWVSQTAANLVIGYDLSTGI
MUL_2368|M.ulcerans_Agy99           G-VDPLILRQAYPVSQDPYGLAGSNQ---LAWVSQTAANLVIGYDLSTGI
MAV_2355|M.avium_104                G-VDPLILRQAYPVPQAPYGLAGSRA---LAWVSQTVSNIVIGYDLSTGI
Mflv_3041|M.gilvum_PYR-GCK          G-VDPLILRQRYPVPDAPYGLAGSTDPKGLAWVAQTANNTVVGYDLATGI
Mvan_3485|M.vanbaalenii_PYR-1       G-VNPLILRQRYPVPDAPYAVAGSRDDDGLAWVAQTATNTVVGYDLSTGI
MSMEG_4196|M.smegmatis_MC2_155      S-VDPLILRQRSPVRGAPYGLAGSAN---LVWVSETSTNTVIGYDLSTGI
TH_2366|M.thermoresistible__bu      S-VDPLLMRQRYPVPDSPYGLAGSRS---LTWVSQTATNTVIGYDLSTGI
MAB_2106c|M.abscessus_ATCC_199      GLADSLILRQRYPVPGAPYGLAYSAT---LIWVSQTATNTVIGYDLSTGI
                                    . .:.*::**  **   **.:* *     * **::*  * *:****:***

Mb2162|M.bovis_AF2122/97            PVEKVRYPTVQQPNSLAFDETSDTLYVVSGSGAGSRFIEHAAGTR
Rv2138|M.tuberculosis_H37Rv         PVEKVRYPTVQQPNSLAFDETSDTLYVVSGSGAGVQVIEHAAGTR
MMAR_3118|M.marinum_M               PVEKVRYPTVQQPNSLAFDEASGTLFVVSGSGAGVQVIEHAAGVP
MUL_2368|M.ulcerans_Agy99           PVEKVRYPTVQQPNSLAFDEASGTLFVVSGSGAGVQVIEHAAGVP
MAV_2355|M.avium_104                PVEKVRYPTVQQPNSLAFDEASDTLYVVSGSGAGVQVIDHAAGKR
Mflv_3041|M.gilvum_PYR-GCK          PVEKVRYPTVQQPNSLAYDDASDTLYVASGSGAGVQVIADAGGPR
Mvan_3485|M.vanbaalenii_PYR-1       PVEKVRYRTVQQPNSLAFDDASGTLYVVSGAGAGVQVITGAAK--
MSMEG_4196|M.smegmatis_MC2_155      PVEKVRYRTVQQPNSLAYDETSGTLYVVSATGAGVQVIPDATVGP
TH_2366|M.thermoresistible__bu      PVERIRYRTVQQPNALAFDDASGTLYVVSGSGAGVQIISDAVVSG
MAB_2106c|M.abscessus_ATCC_199      PEERARFATVRQPNSLVSDGS--TLFVASGAGDGIQATDIRSLG-
                                    * *: *: **:***:*. * :  **:*.*.:* * :