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MTGKRVERVHAINWNRLLDAKDLQVWERLTGNFWLPEKIPLSNDLASWQTLSSTEQQTTIRVFTGLTLLD TAQATVGAVAMIDDAVTPHEEAVLTNMAFMESVHAKSYSSIFSTLCSTKQIDDAFDWSEQNPYLQRKAQI IVDYYRGDDALKRKASSVMLESFLFYSGFYLPMYWSSRGKLTNTADLIRLIIRDEAVHGYYIGYKCQRGL ADLTDAERADHREYTCELLHTLYANEIDYAHDLYDELGWTDDVLPYMRYNANKALANLGYQPAFDRDTCQ VNPAVRAALDPGAGENHDFFSGSGSSYVMGTHQPTTDTDWDF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2003c | nrdF1 | - | 100% (322) | ribonucleotide-diphosphate reductase subunit beta |
| M. bovis AF2122 / 97 | Mb3074c | nrdF2 | e-135 | 70.85% (319) | ribonucleotide-diphosphate reductase subunit beta |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4286 | nrdF | 1e-134 | 70.22% (319) | ribonucleotide-diphosphate reductase subunit beta |
| M. tuberculosis H37Rv | Rv1981c | nrdF1 | 0.0 | 99.69% (322) | ribonucleotide-diphosphate reductase subunit beta |
| M. leprae Br4923 | MLBr_01731 | nrdF | 1e-135 | 70.37% (324) | ribonucleotide-diphosphate reductase subunit beta |
| M. abscessus ATCC 19977 | MAB_3404c | nrdF | 1e-136 | 71.16% (319) | ribonucleotide-diphosphate reductase subunit beta |
| M. marinum M | MMAR_1647 | nrdF | 1e-135 | 70.53% (319) | ribonucleoside-diphosphate reductase (beta chain) NrdF2 |
| M. avium 104 | MAV_3913 | nrdF | 1e-135 | 70.53% (319) | ribonucleotide-diphosphate reductase subunit beta |
| M. smegmatis MC2 155 | MSMEG_2313 | nrdF2 | 1e-134 | 70.53% (319) | ribonucleotide-diphosphate reductase subunit beta |
| M. thermoresistible (build 8) | TH_1825 | nrdG | 1e-134 | 70.53% (319) | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDF2 |
| M. ulcerans Agy99 | MUL_1883 | nrdF | 1e-135 | 70.53% (319) | ribonucleotide-diphosphate reductase subunit beta |
| M. vanbaalenii PYR-1 | Mvan_2060 | nrdF | 1e-134 | 70.22% (319) | ribonucleotide-diphosphate reductase subunit beta |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1647|M.marinum_M -------------MTGNAKLIDRVSAINWNRVQDEKDAEVWDRLTGNFWL
MUL_1883|M.ulcerans_Agy99 -------------MTGNAKLIDRVSAINWNRVQDEKDAEVWDRLTGNFWL
MLBr_01731|M.leprae_Br4923 ------------MLTGKMKLIDRVSAINWNWLQDDKDAEVWDRLTGNFWL
Mflv_4286|M.gilvum_PYR-GCK -----------------MKLIDRVSAINWNRLQDDKDAEVWDRLTGNFWL
Mvan_2060|M.vanbaalenii_PYR-1 -------------MSDGMKLIDRVSAINWNRLQDDKDAEVWERLTGNFWL
MAV_3913|M.avium_104 -------------MSENMKLIDRLSAINWNRLQDDKDAEVWDRLTGNFWL
MSMEG_2313|M.smegmatis_MC2_155 -------------MSDGIKLIDRVSAINWNRLQDEKDAEVWHRLTGNFWL
TH_1825|M.thermoresistible__bu VFGYNVPTSEVGTVSEGMKLVNRVSAINWNRLEDDKDAEVWHRLTGNFWL
MAB_3404c|M.abscessus_ATCC_199 -------------MSEKLKLVSRVSAINWNRVPDEKDAEVWDRLTGNFWL
Mb2003c|M.bovis_AF2122/97 -------------MTG--KRVERVHAINWNRLLDAKDLQVWERLTGNFWL
Rv1981c|M.tuberculosis_H37Rv -------------MTG--KLVERVHAINWNRLLDAKDLQVWERLTGNFWL
* :.*: ***** : * ** :**.********
MMAR_1647|M.marinum_M PEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDA
MUL_1883|M.ulcerans_Agy99 PEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDA
MLBr_01731|M.leprae_Br4923 PEKVPVSNDLPSWGTLTASEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
Mflv_4286|M.gilvum_PYR-GCK PEKVPVSNDIPSWNTLTAHEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
Mvan_2060|M.vanbaalenii_PYR-1 PEKVPVSNDIPSWNTLTAHEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
MAV_3913|M.avium_104 PEKVPVSNDLQSWATLTAHEKQMTMRVFTGLTLLDTIQGTVGAVSLIPDA
MSMEG_2313|M.smegmatis_MC2_155 PEKVPVSNDIQSWHTLTDNEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
TH_1825|M.thermoresistible__bu PEKVPVSNDIPSWNTLTDTEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
MAB_3404c|M.abscessus_ATCC_199 PEKVPVSNDIQSWNTLTDHEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
Mb2003c|M.bovis_AF2122/97 PEKIPLSNDLASWQTLSSTEQQTTIRVFTGLTLLDTAQATVGAVAMIDDA
Rv1981c|M.tuberculosis_H37Rv PEKIPLSNDLASWQTLSSTEQQTTIRVFTGLTLLDTAQATVGAVAMIDDA
***:*:***: ** **: *:* *:*******:*** *.*****::* **
MMAR_1647|M.marinum_M LTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENSNLQ
MUL_1883|M.ulcerans_Agy99 LTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENSNLQ
MLBr_01731|M.leprae_Br4923 LTPHEEAVYTNIAFMESVHAKSYSSIFSTLCSTAEIDEAFRWSEENNNLQ
Mflv_4286|M.gilvum_PYR-GCK LTPHEEAVYTNIAFMESVHARSYSNIFSTLCSTSEIDDAFRWSEENPNLQ
Mvan_2060|M.vanbaalenii_PYR-1 LTPHEEAVYTNIAFMESVHARSYSNIFSTLCSTAEIDDAFRWSEENPNLQ
MAV_3913|M.avium_104 LTPHEEAVYTNIAFMESVHARSYSNIFSTLCSTAEIDDAFRWSEENPNLQ
MSMEG_2313|M.smegmatis_MC2_155 VTPHEEAVLTNIAFMESVHAKSYSNIFSTLCSTAEIDDAFRWSEENPNLQ
TH_1825|M.thermoresistible__bu LTPHEEAVLTNIAFMESVHAKSYSNIFSTLCSTAEIDDAFRWSEENPNLQ
MAB_3404c|M.abscessus_ATCC_199 ITPHEEAVYTNIAFMESVHAKSYSSIFSTLCSTREIDDAFRWSEENPNLQ
Mb2003c|M.bovis_AF2122/97 VTPHEEAVLTNMAFMESVHAKSYSSIFSTLCSTKQIDDAFDWSEQNPYLQ
Rv1981c|M.tuberculosis_H37Rv VTPHEEAVLTNMAFMESVHAKSYSSIFSTLCSTKQIDDAFDWSEQNPYLQ
:******* **:********:***.******** :**:** ***:* **
MMAR_1647|M.marinum_M RKAEIVLEYYRGDDPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
MUL_1883|M.ulcerans_Agy99 RKAEIVLEYYRGDDPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
MLBr_01731|M.leprae_Br4923 RKAKIVMEYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
Mflv_4286|M.gilvum_PYR-GCK RKAEIVMQYYKGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
Mvan_2060|M.vanbaalenii_PYR-1 RKAEIVMQYYKGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
MAV_3913|M.avium_104 RKAEIVMQYYKGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
MSMEG_2313|M.smegmatis_MC2_155 RKAAIVMQYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
TH_1825|M.thermoresistible__bu RKAEIVMQYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
MAB_3404c|M.abscessus_ATCC_199 RKAEIVMEYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
Mb2003c|M.bovis_AF2122/97 RKAQIIVDYYRGDDALKRKASSVMLESFLFYSGFYLPMYWSSRGKLTNTA
Rv1981c|M.tuberculosis_H37Rv RKAQIIVDYYRGDDALKRKASSVMLESFLFYSGFYLPMYWSSRGKLTNTA
*** *:::**:**:.****.:*.:*******************.******
MMAR_1647|M.marinum_M DMIRLIIRDEAVHGYYIGYKFQRGLAAADEARRTELKDYTYELLFELYDN
MUL_1883|M.ulcerans_Agy99 DMIRLIIRDEAVHGYYIGYKFQRGLAAADEARRTELKDYTYELLFELYDN
MLBr_01731|M.leprae_Br4923 DMIRLIIRDEAVHGYYIGYKFQRGLVLVDDARRAELKEYTYELLFELYDN
Mflv_4286|M.gilvum_PYR-GCK DMIRLIIRDEAVHGYYIGYKFQKGLALADDATRQELKDYTYELLFELYDN
Mvan_2060|M.vanbaalenii_PYR-1 DMIRLIIRDEAVHGYYIGYKFQKGLALESEATRQELKDYTYELLFELYDN
MAV_3913|M.avium_104 DMIRLIIRDEAVHGYYIGYKYQRGLALVDDAKRQELKDYTYELLFELYDN
MSMEG_2313|M.smegmatis_MC2_155 DMIRLIIRDEAVHGYYIGYKYQRGLALVDEEKKQELKDYTYELLFELYDN
TH_1825|M.thermoresistible__bu DMIRLIIRDEAVHGYYIGYKYQRGLAMVEPAKQKELKDYTYDLLFELYDN
MAB_3404c|M.abscessus_ATCC_199 DMIRLIIRDEAVHGYYIGYKFQRGLERVDEAKRAEIKEYTYDLLYELYEN
Mb2003c|M.bovis_AF2122/97 DLIRLIIRDEAVHGYYIGYKCQRGLADLTDAERADHREYTCELLHTLYAN
Rv1981c|M.tuberculosis_H37Rv DLIRLIIRDEAVHGYYIGYKCQRGLADLTDAERADHREYTCELLHTLYAN
*:****************** *:** : : ::** :**. ** *
MMAR_1647|M.marinum_M EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
MUL_1883|M.ulcerans_Agy99 EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
MLBr_01731|M.leprae_Br4923 EVEYTQDLYDRVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
Mflv_4286|M.gilvum_PYR-GCK EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
Mvan_2060|M.vanbaalenii_PYR-1 EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
MAV_3913|M.avium_104 EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
MSMEG_2313|M.smegmatis_MC2_155 EVEYTQDLYDSVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
TH_1825|M.thermoresistible__bu EVEYTQDLYDDVGLTEDVKKFLRYNANKALMNLGYEALFPKDETDVNPAI
MAB_3404c|M.abscessus_ATCC_199 ETDYTEDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPREETDVNPAI
Mb2003c|M.bovis_AF2122/97 EIDYAHDLYDELGWTDDVLPYMRYNANKALANLGYQPAFDRDTCQVNPAV
Rv1981c|M.tuberculosis_H37Rv EIDYAHDLYDELGWTDDVLPYMRYNANKALANLGYQPAFDRDTCQVNPAV
* :*:.**** :* *:** ::******** ****:. * :: :****:
MMAR_1647|M.marinum_M LSALSPNADENHDFFSGSGSSYVIGKAVVTQDEDWDF
MUL_1883|M.ulcerans_Agy99 LSALSPNADENHDFFSGSGSSYVIGKAVATQDEDWDF
MLBr_01731|M.leprae_Br4923 LSALSPNADENHDFFSGSGSSYVIGKAVVTEDEDWDF
Mflv_4286|M.gilvum_PYR-GCK LSALSPNADENHDFFSGSGSSYVIGKAVITEDEDWDF
Mvan_2060|M.vanbaalenii_PYR-1 LSALSPNADENHDFFSGSGSSYVIGKAVNTEDEDWDF
MAV_3913|M.avium_104 LSALSPNADENHDFFSGSGSSYVIGKAVVTEDEDWDF
MSMEG_2313|M.smegmatis_MC2_155 LSALAPNADENHDFFSGSGSSYVIGKAVNTEDEDWDF
TH_1825|M.thermoresistible__bu LSALAPNADENHDFFSGSGSSYVIGKAVVTEDEDWDF
MAB_3404c|M.abscessus_ATCC_199 LSALSPNADENHDFFSGSGSSYVIGKAVNTEDEDWDF
Mb2003c|M.bovis_AF2122/97 RAALDPGAGENHDFFSGSGSSYVMGTHQPTTDTDWDF
Rv1981c|M.tuberculosis_H37Rv RAALDPGAGENHDFFSGSGSSYVMGTHQPTTDTDWDF
:** *.*.**************:*. * * ****