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LTGKMKLIDRVSAINWNWLQDDKDAEVWDRLTGNFWLPEKVPVSNDLPSWGTLTASEKQLTMRVFTGLTL LDTIQGTVGAVSLIPDALTPHEEAVYTNIAFMESVHAKSYSSIFSTLCSTAEIDEAFRWSEENNNLQRKA KIVMEYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQR GLVLVDDARRAELKEYTYELLFELYDNEVEYTQDLYDRVGLTEDVKKFLRYNANKALMNLGYEALFPRDE TDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVVTEDEDWDF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01731 | nrdF | - | 100% (325) | ribonucleotide-diphosphate reductase subunit beta |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3074c | nrdF2 | 1e-179 | 93.52% (324) | ribonucleotide-diphosphate reductase subunit beta |
| M. gilvum PYR-GCK | Mflv_4286 | nrdF | 1e-177 | 93.75% (320) | ribonucleotide-diphosphate reductase subunit beta |
| M. tuberculosis H37Rv | Rv3048c | nrdF2 | 1e-179 | 93.52% (324) | ribonucleotide-diphosphate reductase subunit beta |
| M. abscessus ATCC 19977 | MAB_3404c | nrdF | 1e-172 | 90.34% (321) | ribonucleotide-diphosphate reductase subunit beta |
| M. marinum M | MMAR_1647 | nrdF | 1e-178 | 92.59% (324) | ribonucleoside-diphosphate reductase (beta chain) NrdF2 |
| M. avium 104 | MAV_3913 | nrdF | 1e-177 | 94.06% (320) | ribonucleotide-diphosphate reductase subunit beta |
| M. smegmatis MC2 155 | MSMEG_2313 | nrdF2 | 1e-172 | 91.56% (320) | ribonucleotide-diphosphate reductase subunit beta |
| M. thermoresistible (build 8) | TH_1825 | nrdG | 1e-173 | 91.25% (320) | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDF2 |
| M. ulcerans Agy99 | MUL_1883 | nrdF | 1e-177 | 92.28% (324) | ribonucleotide-diphosphate reductase subunit beta |
| M. vanbaalenii PYR-1 | Mvan_2060 | nrdF | 1e-175 | 93.12% (320) | ribonucleotide-diphosphate reductase subunit beta |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3074c|M.bovis_AF2122/97 -------------MTGNAKLIDRVSAINWNRLQDEKDAEVWDRLTGNFWL
Rv3048c|M.tuberculosis_H37Rv -------------MTGNAKLIDRVSAINWNRLQDEKDAEVWDRLTGNFWL
MMAR_1647|M.marinum_M -------------MTGNAKLIDRVSAINWNRVQDEKDAEVWDRLTGNFWL
MUL_1883|M.ulcerans_Agy99 -------------MTGNAKLIDRVSAINWNRVQDEKDAEVWDRLTGNFWL
MLBr_01731|M.leprae_Br4923 ------------MLTGKMKLIDRVSAINWNWLQDDKDAEVWDRLTGNFWL
Mflv_4286|M.gilvum_PYR-GCK -----------------MKLIDRVSAINWNRLQDDKDAEVWDRLTGNFWL
Mvan_2060|M.vanbaalenii_PYR-1 -------------MSDGMKLIDRVSAINWNRLQDDKDAEVWERLTGNFWL
MAV_3913|M.avium_104 -------------MSENMKLIDRLSAINWNRLQDDKDAEVWDRLTGNFWL
MSMEG_2313|M.smegmatis_MC2_155 -------------MSDGIKLIDRVSAINWNRLQDEKDAEVWHRLTGNFWL
TH_1825|M.thermoresistible__bu VFGYNVPTSEVGTVSEGMKLVNRVSAINWNRLEDDKDAEVWHRLTGNFWL
MAB_3404c|M.abscessus_ATCC_199 -------------MSEKLKLVSRVSAINWNRVPDEKDAEVWDRLTGNFWL
**:.*:****** : *:******.********
Mb3074c|M.bovis_AF2122/97 PEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDA
Rv3048c|M.tuberculosis_H37Rv PEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDA
MMAR_1647|M.marinum_M PEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDA
MUL_1883|M.ulcerans_Agy99 PEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDA
MLBr_01731|M.leprae_Br4923 PEKVPVSNDLPSWGTLTASEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
Mflv_4286|M.gilvum_PYR-GCK PEKVPVSNDIPSWNTLTAHEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
Mvan_2060|M.vanbaalenii_PYR-1 PEKVPVSNDIPSWNTLTAHEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
MAV_3913|M.avium_104 PEKVPVSNDLQSWATLTAHEKQMTMRVFTGLTLLDTIQGTVGAVSLIPDA
MSMEG_2313|M.smegmatis_MC2_155 PEKVPVSNDIQSWHTLTDNEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
TH_1825|M.thermoresistible__bu PEKVPVSNDIPSWNTLTDTEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
MAB_3404c|M.abscessus_ATCC_199 PEKVPVSNDIQSWNTLTDHEKQLTMRVFTGLTLLDTIQGTVGAVSLIPDA
*********: ** *** ***:*********:*****************
Mb3074c|M.bovis_AF2122/97 LTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENRNLQ
Rv3048c|M.tuberculosis_H37Rv LTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENRNLQ
MMAR_1647|M.marinum_M LTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENSNLQ
MUL_1883|M.ulcerans_Agy99 LTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENSNLQ
MLBr_01731|M.leprae_Br4923 LTPHEEAVYTNIAFMESVHAKSYSSIFSTLCSTAEIDEAFRWSEENNNLQ
Mflv_4286|M.gilvum_PYR-GCK LTPHEEAVYTNIAFMESVHARSYSNIFSTLCSTSEIDDAFRWSEENPNLQ
Mvan_2060|M.vanbaalenii_PYR-1 LTPHEEAVYTNIAFMESVHARSYSNIFSTLCSTAEIDDAFRWSEENPNLQ
MAV_3913|M.avium_104 LTPHEEAVYTNIAFMESVHARSYSNIFSTLCSTAEIDDAFRWSEENPNLQ
MSMEG_2313|M.smegmatis_MC2_155 VTPHEEAVLTNIAFMESVHAKSYSNIFSTLCSTAEIDDAFRWSEENPNLQ
TH_1825|M.thermoresistible__bu LTPHEEAVLTNIAFMESVHAKSYSNIFSTLCSTAEIDDAFRWSEENPNLQ
MAB_3404c|M.abscessus_ATCC_199 ITPHEEAVYTNIAFMESVHAKSYSSIFSTLCSTREIDDAFRWSEENPNLQ
:******* ***********:***.******** ***:******** ***
Mb3074c|M.bovis_AF2122/97 RKAEIVLQYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
Rv3048c|M.tuberculosis_H37Rv RKAEIVLQYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
MMAR_1647|M.marinum_M RKAEIVLEYYRGDDPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
MUL_1883|M.ulcerans_Agy99 RKAEIVLEYYRGDDPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
MLBr_01731|M.leprae_Br4923 RKAKIVMEYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
Mflv_4286|M.gilvum_PYR-GCK RKAEIVMQYYKGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
Mvan_2060|M.vanbaalenii_PYR-1 RKAEIVMQYYKGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
MAV_3913|M.avium_104 RKAEIVMQYYKGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
MSMEG_2313|M.smegmatis_MC2_155 RKAAIVMQYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
TH_1825|M.thermoresistible__bu RKAEIVMQYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
MAB_3404c|M.abscessus_ATCC_199 RKAEIVMEYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTA
*** **::**:**:************************************
Mb3074c|M.bovis_AF2122/97 DMIRLIIRDEAVHGYYIGYKFQRGLALVDDVTRAELKDYTYELLFELYDN
Rv3048c|M.tuberculosis_H37Rv DMIRLIIRDEAVHGYYIGYKFQRGLALVDDVTRAELKDYTYELLFELYDN
MMAR_1647|M.marinum_M DMIRLIIRDEAVHGYYIGYKFQRGLAAADEARRTELKDYTYELLFELYDN
MUL_1883|M.ulcerans_Agy99 DMIRLIIRDEAVHGYYIGYKFQRGLAAADEARRTELKDYTYELLFELYDN
MLBr_01731|M.leprae_Br4923 DMIRLIIRDEAVHGYYIGYKFQRGLVLVDDARRAELKEYTYELLFELYDN
Mflv_4286|M.gilvum_PYR-GCK DMIRLIIRDEAVHGYYIGYKFQKGLALADDATRQELKDYTYELLFELYDN
Mvan_2060|M.vanbaalenii_PYR-1 DMIRLIIRDEAVHGYYIGYKFQKGLALESEATRQELKDYTYELLFELYDN
MAV_3913|M.avium_104 DMIRLIIRDEAVHGYYIGYKYQRGLALVDDAKRQELKDYTYELLFELYDN
MSMEG_2313|M.smegmatis_MC2_155 DMIRLIIRDEAVHGYYIGYKYQRGLALVDEEKKQELKDYTYELLFELYDN
TH_1825|M.thermoresistible__bu DMIRLIIRDEAVHGYYIGYKYQRGLAMVEPAKQKELKDYTYDLLFELYDN
MAB_3404c|M.abscessus_ATCC_199 DMIRLIIRDEAVHGYYIGYKFQRGLERVDEAKRAEIKEYTYDLLYELYEN
********************:*:** . : *:*:***:**:***:*
Mb3074c|M.bovis_AF2122/97 EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
Rv3048c|M.tuberculosis_H37Rv EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
MMAR_1647|M.marinum_M EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
MUL_1883|M.ulcerans_Agy99 EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
MLBr_01731|M.leprae_Br4923 EVEYTQDLYDRVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
Mflv_4286|M.gilvum_PYR-GCK EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
Mvan_2060|M.vanbaalenii_PYR-1 EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
MAV_3913|M.avium_104 EVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
MSMEG_2313|M.smegmatis_MC2_155 EVEYTQDLYDSVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAI
TH_1825|M.thermoresistible__bu EVEYTQDLYDDVGLTEDVKKFLRYNANKALMNLGYEALFPKDETDVNPAI
MAB_3404c|M.abscessus_ATCC_199 ETDYTEDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPREETDVNPAI
*.:**:**** *****************************::********
Mb3074c|M.bovis_AF2122/97 LSALSPNADENHDFFSGSGSSYVIGKAVVTEDDDWDF
Rv3048c|M.tuberculosis_H37Rv LSALSPNADENHDFFSGSGSSYVIGKAVVTEDDDWDF
MMAR_1647|M.marinum_M LSALSPNADENHDFFSGSGSSYVIGKAVVTQDEDWDF
MUL_1883|M.ulcerans_Agy99 LSALSPNADENHDFFSGSGSSYVIGKAVATQDEDWDF
MLBr_01731|M.leprae_Br4923 LSALSPNADENHDFFSGSGSSYVIGKAVVTEDEDWDF
Mflv_4286|M.gilvum_PYR-GCK LSALSPNADENHDFFSGSGSSYVIGKAVITEDEDWDF
Mvan_2060|M.vanbaalenii_PYR-1 LSALSPNADENHDFFSGSGSSYVIGKAVNTEDEDWDF
MAV_3913|M.avium_104 LSALSPNADENHDFFSGSGSSYVIGKAVVTEDEDWDF
MSMEG_2313|M.smegmatis_MC2_155 LSALAPNADENHDFFSGSGSSYVIGKAVNTEDEDWDF
TH_1825|M.thermoresistible__bu LSALAPNADENHDFFSGSGSSYVIGKAVVTEDEDWDF
MAB_3404c|M.abscessus_ATCC_199 LSALSPNADENHDFFSGSGSSYVIGKAVNTEDEDWDF
****:*********************** *:*:****