For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VRIKIFMLVTAVVLLCCSGVATAAPKTYCEELKGTDTGQACQIQMSDPAYNINISLPSYYPDQKSLENYI AQTRDKFLSAATSSTPREAPYELNITSATYQSAIPPRGTQAVVLKVYQNAGGTHPTTTYKAFDWDQAYRK PITYDTLWQADTDPLPVVFPIVQGELSKQTGQQVSIAPNAGLDPVNYQNFAVTNDGVIFFFNPGELLPEA AGPTQVLVPRSAIDSMLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2002c | mpt64 | - | 100% (228) | immunogenic protein MPT64 (antigen MPT64/MPB64) |
| M. bovis AF2122 / 97 | Mb3062c | TB22.2 | 7e-53 | 45.91% (220) | hypothetical protein Mb3062c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4267 | - | 2e-47 | 42.58% (209) | immunogenic protein MPB64/MPT64 precursor |
| M. tuberculosis H37Rv | Rv1980c | mpt64 | 1e-132 | 100.00% (228) | immunogenic protein MPT64 (antigen MPT64/MPB64) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1835c | - | 5e-59 | 44.40% (268) | immunogenic protein MPT64 precursor |
| M. marinum M | MMAR_5409 | mpt64 | 2e-87 | 66.08% (227) | immunogenic protein Mpt64 |
| M. avium 104 | MAV_4130 | - | 9e-69 | 54.62% (249) | immunogenic protein MPT64 |
| M. smegmatis MC2 155 | MSMEG_2331 | - | 4e-48 | 42.22% (225) | immunogenic protein MPB64/MPT64 |
| M. thermoresistible (build 8) | TH_2187 | - | 1e-52 | 46.05% (215) | PROBABLE CONSERVED SECRETED PROTEIN TB22.2 |
| M. ulcerans Agy99 | MUL_5032 | mpt64 | 1e-87 | 66.52% (227) | immunogenic protein Mpt64 |
| M. vanbaalenii PYR-1 | Mvan_2092 | - | 1e-48 | 43.96% (207) | immunogenic protein MPB64/MPT64 precursor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2002c|M.bovis_AF2122/97 -----MR-IKIFM------LVTAVVLLCCSGVATAAP-KTYCEELKGTDT
Rv1980c|M.tuberculosis_H37Rv -----MR-IKIFM------LVTAVVLLCCSGVATAAP-KTYCEELKGTDT
MMAR_5409|M.marinum_M -----MRHIMMFV------LITFATLFGSTGLAAAAPPKSYCDELKGTTT
MUL_5032|M.ulcerans_Agy99 -----MRHIMMFV------LVTFATLFGSTGLAAAAPPKSYCDELKGTTT
MAB_1835c|M.abscessus_ATCC_199 MPYLSLRSISASV------LVTAASIFGFSGVAGAAP-HDYCGDLKGTNT
MAV_4130|M.avium_104 -----MRSFSVAA------FAAALVLAGPAGAAAAAP-KDYCADLKGANT
Mflv_4267|M.gilvum_PYR-GCK -----MRFLAAALTAAAVSASLAAGPAALAQPAPPA-TPSACVALSGTVD
Mvan_2092|M.vanbaalenii_PYR-1 -----MRIFAAALTAAGATAGLLAVPAAGLLAAPAAGAQSACAELGGTVD
TH_2187|M.thermoresistible__bu -----MRILKT-------TAALLAGGLISCSIPGTAGAQTACDALGGTVA
MSMEG_2331|M.smegmatis_MC2_155 -----MRISTV-------VGVLAAGVLIGGVAAPSAAAQSTCAELGGTVD
:* . .* * * *:
Mb2002c|M.bovis_AF2122/97 G-QACQIQMSDPAYNINISLPSYYPDQKSLENYIAQTRDKFLSAATSSTP
Rv1980c|M.tuberculosis_H37Rv G-QACQIQMSDPAYNINISLPSYYPDQKSLENYIAQTRDKFLSAATSSTP
MMAR_5409|M.marinum_M G-EVCKIQMTEPGYTVDISLPSNYPDGKSLESFVRETGEHFLDKAKSSAA
MUL_5032|M.ulcerans_Agy99 G-EVCKIQMTEPGYTVDISLPSNYPDGKSLESFVRETGEHFLDKAKSSTA
MAB_1835c|M.abscessus_ATCC_199 G-KTCEIRLSDTGYSVDVTIPLNYPDQKSIAEYVAKTRDAFVNAAKSGAA
MAV_4130|M.avium_104 G-QTCQIQMADPGYNVDISFPANYPDEQPVADFISKQRDDFLNAAKSSAP
Mflv_4267|M.gilvum_PYR-GCK TDDMCLVQVENPTYRLDYSFPADYPDQQALTAYLTQTRDGFVNVAGMPGS
Mvan_2092|M.vanbaalenii_PYR-1 AEQTCHVHAENSTYRLDYTFPVDYPDQQALAAYLTQTRDGFVNVSEMPGS
TH_2187|M.thermoresistible__bu DDRRCEVHAETPTYLLDMVFPVDYPDQQALTDYLIQTRDGFVNVSEMPGS
MSMEG_2331|M.smegmatis_MC2_155 ADQICQVHTANATYRLDYTFSTTYPDQEAVVGYLSQTRDGFVNVSDMPGS
* :: . * :: :. *** :.: :: : : *:. : .
Mb2002c|M.bovis_AF2122/97 REAPYELNITSATYQSAIPP---RGTQAVVLKVYQNAGGTHPTTTYKAFD
Rv1980c|M.tuberculosis_H37Rv REAPYELNITSATYQSAIPP---RGTQAVVLKVYQNAGGTHPTTTYKAFD
MMAR_5409|M.marinum_M RDAPYELDITSTNYESAIPP---RGTQSVVLKIYQNVGGPRPQTTYKAFN
MUL_5032|M.ulcerans_Agy99 RDAPYELDITSTHYESAIPP---RGTQSVVLKIYQNVGGPRPQTTYKAFN
MAB_1835c|M.abscessus_ATCC_199 RSTTAQLSMKPTEYNSDLPP---RGTQTVVFKVYQTGGNGQPQTAYKAFN
MAV_4130|M.avium_104 RDQPYQLTITSAKYGSAIPP---RGTEAVVLKVVQNTGAG-PHTTYKSFN
Mflv_4267|M.gilvum_PYR-GCK WNLPYVLDGRGTGYRTGPDD---GGTRSVVFEMYENVGGAHPQTWFKSFN
Mvan_2092|M.vanbaalenii_PYR-1 WNLPYVLDGRGTGYRTGPDG---AGTRSVVFEVYENVGGAHPQTWFKAFN
TH_2187|M.thermoresistible__bu RNLPYALDARATEYRSGDAA---TGTRSVVFEVYQNVGGAHPTTWYQAFN
MSMEG_2331|M.smegmatis_MC2_155 RDQPYVLDARGSSYSSAVAPGLPARTQSLVLEVFQDVGGAQPETWYKSFN
. . * : * : *.::*::: : * * * :::*:
Mb2002c|M.bovis_AF2122/97 WDQAYRKPITYDT---------LWQADTDPLPVVFPIVQGELSKQTGQQ-
Rv1980c|M.tuberculosis_H37Rv WDQAYRKPITYDT---------LWQADTDPLPVVFPIVQGELSKQTGQQ-
MMAR_5409|M.marinum_M WDQAYRKPITWDK---------LWQPETDPLKVVFPIVESELSKQSEEQ-
MUL_5032|M.ulcerans_Agy99 WDQAYRKPITWEK---------LWQPETDPLEVVFPIVESELSKQSEEQ-
MAB_1835c|M.abscessus_ATCC_199 WDQSYRKPVLYTVPKDDKDDAPLWRVD-DPLKTVAPIVQAQLQQQLAPPP
MAV_4130|M.avium_104 WDQAYRKEIVWTAAADDKKNTPLWRVD-DPLATVAPIVQSELQKQTAPP-
Mflv_4267|M.gilvum_PYR-GCK WDVAKKAPITFDT---------LFKPGSEPLAVIFPIVRSDISRQLGIE-
Mvan_2092|M.vanbaalenii_PYR-1 WDVAKKAPITFDT---------LFRPDTKPLDVIFPIVQKDISRQLGVD-
TH_2187|M.thermoresistible__bu YDLRTRAPITFDT---------LFDPESAPLEVIYPVVQRELQELTGID-
MSMEG_2331|M.smegmatis_MC2_155 YDLVKRAPITFDT---------LFKPGSRPLDVIFPIVARELETQAGIV-
:* : : : *: ** .: *:* ::.
Mb2002c|M.bovis_AF2122/97 --------------------------------VSIAPNAGLDPVNYQNFA
Rv1980c|M.tuberculosis_H37Rv --------------------------------VSIAPNAGLDPVNYQNFA
MMAR_5409|M.marinum_M --------------------------------VVIASSAGLDPKNYQNFA
MUL_5032|M.ulcerans_Agy99 --------------------------------VVIASSAGLDPKNYQNFA
MAB_1835c|M.abscessus_ATCC_199 VATPTPTTTSGQPTTTTSTTTTSTTPPPPPPPLPFSPATLYDPANYQNFA
MAV_4130|M.avium_104 ----------ANPNQPAPPANQPASPTPTAPPVTVASAAAYDPANYQSFA
Mflv_4267|M.gilvum_PYR-GCK --------------------------------APITTADGLDPAKYTEFA
Mvan_2092|M.vanbaalenii_PYR-1 --------------------------------APISAADGLDPAKYQEFA
TH_2187|M.thermoresistible__bu --------------------------------QPILPEDGLDPANYQNFA
MSMEG_2331|M.smegmatis_MC2_155 --------------------------------QSISQSAGMDPTHYQNFA
. ** :* .**
Mb2002c|M.bovis_AF2122/97 VTNDGVIFFFNPGELLPEAAGPTQVLVPRSAIDSMLA--------
Rv1980c|M.tuberculosis_H37Rv VTNDGVIFFFNPGELLPEAAGPTQVLVPRSAIDSMLA--------
MMAR_5409|M.marinum_M ISNDGITFFFSPGELLPEAAGARQVLVPRAAVDPMLA--------
MUL_5032|M.ulcerans_Agy99 ISNDGITFFFSPGELLPEAAGARQVLVPRAAVDPMLA--------
MAB_1835c|M.abscessus_ATCC_199 VLNDGIRFFFDQGAILPDSYGALQVLVPRSAIDPMIA--------
MAV_4130|M.avium_104 ITNDGVIFFFDQGRLLPDSAGAPQVLVPRSAIDPMLA--------
Mflv_4267|M.gilvum_PYR-GCK ITDDAVIFYFGQGEIMAGAGGALQATIPRSEIASMLALEPVPVTP
Mvan_2092|M.vanbaalenii_PYR-1 LTDDSLIFYFGQGEIMPGAGGALQATVPRSAVAAMLAEPAVTQG-
TH_2187|M.thermoresistible__bu LTDDEVIFFFSQGELLPHAAGVSQVSVPRTVLVNLLTV-------
MSMEG_2331|M.smegmatis_MC2_155 ITDDSVIFFFDRGALVADSAGALQASVPRWAVASLLA--------
: :* : *:*. * ::. : * *. :** : :::