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VIRHFLRDDDLSPAEQAEVLELAAELKKDPVSRRPLQGPRGVAVIFDKNSTRTRFSFELGIAQLGGHAVV VDSGSTQLGRDETLQDTAKVLSRYVDAIVWRTFGQERLDAMASVATVPVINALSDEFHPCQVLADLQTIA ERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVAAPEGFLPDPSVRAAAERRAQDTGASVTVTAD AHAAAAGADVLVTDTWTSMGQENDGLDRVKPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDG PASAVWDEAENRLHAQKALLVWLLERS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1684 | argF | - | 100% (307) | ornithine carbamoyltransferase |
M. bovis AF2122 / 97 | Mb1415 | pyrB | 2e-20 | 29.84% (315) | aspartate carbamoyltransferase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_3526 | - | 1e-141 | 80.98% (305) | ornithine carbamoyltransferase |
M. tuberculosis H37Rv | Rv1656 | argF | 1e-174 | 100.00% (307) | ornithine carbamoyltransferase |
M. leprae Br4923 | MLBr_01410 | argF | 1e-151 | 85.53% (304) | ornithine carbamoyltransferase |
M. abscessus ATCC 19977 | MAB_2340 | - | 1e-140 | 80.26% (304) | ornithine carbamoyltransferase |
M. marinum M | MMAR_2466 | argF | 1e-154 | 86.93% (306) | ornithine carbamoyltransferase, anabolic ArgF |
M. avium 104 | MAV_3114 | argF | 1e-143 | 81.25% (304) | ornithine carbamoyltransferase |
M. smegmatis MC2 155 | MSMEG_3772 | argF | 1e-142 | 80.39% (306) | ornithine carbamoyltransferase |
M. thermoresistible (build 8) | TH_1596 | argF | 1e-144 | 81.37% (306) | Probable Ornithine carbamoyltransferase, anabolic ArgF |
M. ulcerans Agy99 | MUL_1648 | argF | 1e-154 | 85.95% (306) | ornithine carbamoyltransferase |
M. vanbaalenii PYR-1 | Mvan_3310 | - | 1e-142 | 81.31% (305) | ornithine carbamoyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3526|M.gilvum_PYR-GCK --------------MTRHFLRDDDLTPEEQAEVLALAAALKKDPFSRRPL Mvan_3310|M.vanbaalenii_PYR-1 --------------MTRHFLRDDDLSPEEQAEVLALAADLKKDRFSRRPL MSMEG_3772|M.smegmatis_MC2_155 --------------MIRHFLRDDDLSPEEQAEVLTLAADLKKTPFSRRPL MAB_2340|M.abscessus_ATCC_1997 ---------MIQSKSLRHFLRDDDLSPAEQAEVLTLAAELKKAPFSRRPL TH_1596|M.thermoresistible__bu -----------VSTVIRHFLRDDDLTPEEQAEVLALAAELKRDPLSHRPL Mb1684|M.bovis_AF2122/97 --------------MIRHFLRDDDLSPAEQAEVLELAAELKKDPVSRRPL Rv1656|M.tuberculosis_H37Rv --------------MIRHFLRDDDLSPAEQAEVLELAAELKKDPVSRRPL MLBr_01410|M.leprae_Br4923 MGGASRLRGRGAAQLTRHFLRDDDLSPTEQADILALAADLKKAPFSRRPL MMAR_2466|M.marinum_M --------------MIRHFLRDDDLSPAEQAEVLQLAAELKREPFSRRPL MUL_1648|M.ulcerans_Agy99 --------------MIRHFLRDDDLSPTEQAEVLQLAAELKREPFSRRPL MAV_3114|M.avium_104 -------------MTPRHFLRDDDLSPAEQAEVLALAAELKKDPFSARPL *********:* ***::* *** **: .* *** Mflv_3526|M.gilvum_PYR-GCK EGPRGVAVIFEKNSTRTRFSFEMGIAQLGGHAVVVDGRSTQLGREETLED Mvan_3310|M.vanbaalenii_PYR-1 EGPRGVAVIFEKNSTRTRFSFEMGIAELGGHAVVVDGRSTQLGREETLED MSMEG_3772|M.smegmatis_MC2_155 EGPRGVAVIFEKNSTRTRFSFEMGIAQLGGHAIVVDGRSTQLGREETLED MAB_2340|M.abscessus_ATCC_1997 EGPHGVAVIFEKNSTRTRFSFEMGIAQLGGHAVVVDSRTTQLGREETLED TH_1596|M.thermoresistible__bu EGPRGVAVIFDKNSTRTRFSFEIGIAQLGGHAVVVDGNTTQLGRDETLHD Mb1684|M.bovis_AF2122/97 QGPRGVAVIFDKNSTRTRFSFELGIAQLGGHAVVVDSGSTQLGRDETLQD Rv1656|M.tuberculosis_H37Rv QGPRGVAVIFDKNSTRTRFSFELGIAQLGGHAVVVDSGSTQLGRDETLQD MLBr_01410|M.leprae_Br4923 AGPRGVAVIFDKNSTRTRFSFDIGIAQLGGHAVVVDGLSTQLGRDETLQD MMAR_2466|M.marinum_M DGPRGVAVIFDKNSTRTRFSFEMGIAQLGGHAVVVDGRSTQLGREETLPD MUL_1648|M.ulcerans_Agy99 DGPRGVAVIFDKNSTRTRFSFEMGIAQLGGHAVVVDGRSTQLGREETLPD MAV_3114|M.avium_104 EGPRGVAVLFDKNSTRTRFSFEVGIAQLGGHAVVVDARSTQLGRDETLED **:****:*:**********::***:*****:***. :*****:*** * Mflv_3526|M.gilvum_PYR-GCK TGAVLSRYVDAIVWRTFAQERLTAMASGASVPIVNALSDEFHPCQVLADL Mvan_3310|M.vanbaalenii_PYR-1 TGQVLSRYVDAIVWRTFAQERLTAMASGSTVPIINALSDEFHPCQVLADL MSMEG_3772|M.smegmatis_MC2_155 TGAVLSRYVDAIVWRTFAQERLTAMASGASVPIVNALSDEFHPCQVLADL MAB_2340|M.abscessus_ATCC_1997 TGQVLSRYVEAIVWRTYAQERLTAMASGASVPIVNALSDDFHPCQVLADL TH_1596|M.thermoresistible__bu TGKVLSRYVEAIVWRTFGQDRLIEMAAGATVPVVNALSDEFHPCQVLADL Mb1684|M.bovis_AF2122/97 TAKVLSRYVDAIVWRTFGQERLDAMASVATVPVINALSDEFHPCQVLADL Rv1656|M.tuberculosis_H37Rv TAKVLSRYVDAIVWRTFGQERLDAMASVATVPVINALSDEFHPCQVLADL MLBr_01410|M.leprae_Br4923 TARVLSGYVDAIVWRTFGQHRLDAMAATATVPVVNALSDEFHPCQVLADL MMAR_2466|M.marinum_M TAKVLSRFVDAIVWRTFGQDRLQAMASTATVPVVNALSDEFHPCQVLADL MUL_1648|M.ulcerans_Agy99 TAKVLSRFVDAIVWRTFGQDRLQAMASTATVPVVNALSDEFHPCQVLADL MAV_3114|M.avium_104 TARVLSRYVEAIVWRTFEQHRLEAMAGAATVPVINALSDEFHPCQVLADL *. *** :*:******: *.** **. ::**::*****:********** Mflv_3526|M.gilvum_PYR-GCK QTLIERKGSLKGLRLAYFGDGANNMAHSLMLGGVTAGVDVTIAAPRGFEP Mvan_3310|M.vanbaalenii_PYR-1 QTLAERKGDLKGLRLTYFGDGANNMAHSLMLGGVTAGIHVTIAAPRGFEP MSMEG_3772|M.smegmatis_MC2_155 QTLAERKGKLAGLRMTYFGDGANNMAHSLMLGGVTAGVHVTIAAPDGFEP MAB_2340|M.abscessus_ATCC_1997 QTLAERKGSLDGLRLTYLGDGANNMAHSLMLGGVTAGIHVTIAAPNGFAP TH_1596|M.thermoresistible__bu QTLAERKGSLAGLRLTYLGDGANNMAHSLLLGGVTAGIHVTIAAPAGFAP Mb1684|M.bovis_AF2122/97 QTIAERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVAAPEGFLP Rv1656|M.tuberculosis_H37Rv QTIAERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVAAPEGFLP MLBr_01410|M.leprae_Br4923 QTIAERKGSLNGLRLSYFGDGANNMAHSLMLGAVTAGVHVTVATPVGFTP MMAR_2466|M.marinum_M QTITERRGSLKGLRLSYFGDGANNMAHSLMLGGVTAGMHVTVAAPDGFHP MUL_1648|M.ulcerans_Agy99 QTITERRGSLKGLRLSYFGDGANNMAHSLMLGGVTAGMHVTIAAPDGFHP MAV_3114|M.avium_104 QAIAEHKGSLSGLRMCYLGDGANNMAHSLMLGGVTAGIHVTIAAPDGFTP *:: *::* * ***: *:***********:**.****:.**:*:* ** * Mflv_3526|M.gilvum_PYR-GCK HPMFIAAAETRAHQTGATVAVIDDPLRAADGADVLVTDTWTSMGQENDGL Mvan_3310|M.vanbaalenii_PYR-1 HPMFVAAAETRAHRTGATVTLTDDPVRAADGVDVLVTDTWTSMGQENDGL MSMEG_3772|M.smegmatis_MC2_155 DPRFVDAARRRAAETGATVALTKDAKAGADGADVLVTDTWTSMGQENDGL MAB_2340|M.abscessus_ATCC_1997 HAKYVAEAEKVAATTGASVSVTADPRSAVARADVLVTDAWTSMGQENDGL TH_1596|M.thermoresistible__bu DPEVVAAAEQRARRTGATIAMTDDPRRGAAGADVLVTDTWTSMGQEDDGR Mb1684|M.bovis_AF2122/97 DPSVRAAAERRAQDTGASVTVTADAHAAAAGADVLVTDTWTSMGQENDGL Rv1656|M.tuberculosis_H37Rv DPSVRAAAERRAQDTGASVTVTADAHAAAAGADVLVTDTWTSMGQENDGL MLBr_01410|M.leprae_Br4923 DPSVLAAAKKRAEATGASVTVTVDADTAAAGADVLVTDTWTSMGQENDGL MMAR_2466|M.marinum_M DPSVVGAAEQRAETTGASVRLTADAHVAAAGADVLVTDTWTSMGQEDDGL MUL_1648|M.ulcerans_Agy99 DPSVVGAAEQRAETTGASVRLTADAHVAAAGADVLVTDTWTSMGQEDDGL MAV_3114|M.avium_104 APEFVAAARRRAESTGATVTLTTDARTAARGVDVLVTDTWTSMGQEDDGL . *. * ***:: : *. .. .******:*******:** Mflv_3526|M.gilvum_PYR-GCK DRVRPFRPFQVNADLLGRADSEAVVLHCLPAHRGHEITDEVIDGPRSAVW Mvan_3310|M.vanbaalenii_PYR-1 DRVRPFRPFQVNADMLAHADSEAVVLHCLPAHRGHEITDDVIDGPQSAVW MSMEG_3772|M.smegmatis_MC2_155 DRVRPFRPFQVNADLLELADPAAVVLHCLPAHRGHEITDEVIDGPQSAVF MAB_2340|M.abscessus_ATCC_1997 DRVRPFRAFQVNEDLLALADSEAVVLHCLPAHRGHEITDGVIDGPRSAVW TH_1596|M.thermoresistible__bu DRVRPFRPFQLNADLLGEADPEAVVLHCLPAHRGHEITDEVIDGPQSAVW Mb1684|M.bovis_AF2122/97 DRVKPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDGPASAVW Rv1656|M.tuberculosis_H37Rv DRVKPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDGPASAVW MLBr_01410|M.leprae_Br4923 DRVKPFWPFQVNARLVGLADSEAIVLHCLPAHRGDEITNEVMDGPTSAIW MMAR_2466|M.marinum_M DRVKPFRPFQVNEQLLAAADSEAVVLHCLPAHRGDEITDQVMDGPASAVW MUL_1648|M.ulcerans_Agy99 DRVKPFRPFQVNEQLLAAADSEVVVLHCLPAHRGDEITDQVMDGPASAVW MAV_3114|M.avium_104 DRRTPFWPYQLNADLVSLADPEAIVLHCLPAHRGEEITDEVMDGPSSVVW ** ** .:*:* :: **. .:**********.***: *:*** *.:: Mflv_3526|M.gilvum_PYR-GCK DEAENRLHAQKALLVWLLERS- Mvan_3310|M.vanbaalenii_PYR-1 DEAENRLHAQKALLAWLLERA- MSMEG_3772|M.smegmatis_MC2_155 DEAENRLHAQKALLVWLLEKR- MAB_2340|M.abscessus_ATCC_1997 DEAENRLHAQKALLVWLLENRR TH_1596|M.thermoresistible__bu DEAENRLHAQKALLTWLLERRR Mb1684|M.bovis_AF2122/97 DEAENRLHAQKALLVWLLERS- Rv1656|M.tuberculosis_H37Rv DEAENRLHAQKALLVWLLERS- MLBr_01410|M.leprae_Br4923 DEAENRLHAQKALLVWLLER-- MMAR_2466|M.marinum_M DEAENRLHAQKALLVWLLERGR MUL_1648|M.ulcerans_Agy99 DEAENRLHAQKALLVWLLERGR MAV_3114|M.avium_104 DEAENRLHAQKALLTWLLERQA **************.****.