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VGGASRLRGRGAAQLTRHFLRDDDLSPTEQADILALAADLKKAPFSRRPLAGPRGVAVIFDKNSTRTRFS FDIGIAQLGGHAVVVDGLSTQLGRDETLQDTARVLSGYVDAIVWRTFGQHRLDAMAATATVPVVNALSDE FHPCQVLADLQTIAERKGSLNGLRLSYFGDGANNMAHSLMLGAVTAGVHVTVATPVGFTPDPSVLAAAKK RAEATGASVTVTVDADTAAAGADVLVTDTWTSMGQENDGLDRVKPFWPFQVNARLVGLADSEAIVLHCLP AHRGDEITNEVMDGPTSAIWDEAENRLHAQKALLVWLLER
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01410 | argF | - | 100% (320) | ornithine carbamoyltransferase |
| M. leprae Br4923 | MLBr_00532 | pyrB | 1e-19 | 28.40% (324) | aspartate carbamoyltransferase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1684 | argF | 1e-150 | 85.53% (304) | ornithine carbamoyltransferase |
| M. gilvum PYR-GCK | Mflv_3526 | - | 1e-140 | 80.07% (306) | ornithine carbamoyltransferase |
| M. tuberculosis H37Rv | Rv1656 | argF | 1e-150 | 85.53% (304) | ornithine carbamoyltransferase |
| M. abscessus ATCC 19977 | MAB_2340 | - | 1e-135 | 76.90% (303) | ornithine carbamoyltransferase |
| M. marinum M | MMAR_2466 | argF | 1e-147 | 83.33% (306) | ornithine carbamoyltransferase, anabolic ArgF |
| M. avium 104 | MAV_3114 | argF | 1e-145 | 80.92% (304) | ornithine carbamoyltransferase |
| M. smegmatis MC2 155 | MSMEG_3772 | argF | 1e-139 | 78.43% (306) | ornithine carbamoyltransferase |
| M. thermoresistible (build 8) | TH_1596 | argF | 1e-139 | 78.95% (304) | Probable Ornithine carbamoyltransferase, anabolic ArgF |
| M. ulcerans Agy99 | MUL_1648 | argF | 1e-148 | 83.01% (306) | ornithine carbamoyltransferase |
| M. vanbaalenii PYR-1 | Mvan_3310 | - | 1e-139 | 78.43% (306) | ornithine carbamoyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3526|M.gilvum_PYR-GCK --------------MTRHFLRDDDLTPEEQAEVLALAAALKKDPFSRRPL
Mvan_3310|M.vanbaalenii_PYR-1 --------------MTRHFLRDDDLSPEEQAEVLALAADLKKDRFSRRPL
MSMEG_3772|M.smegmatis_MC2_155 --------------MIRHFLRDDDLSPEEQAEVLTLAADLKKTPFSRRPL
MAB_2340|M.abscessus_ATCC_1997 ---------MIQSKSLRHFLRDDDLSPAEQAEVLTLAAELKKAPFSRRPL
TH_1596|M.thermoresistible__bu -----------VSTVIRHFLRDDDLTPEEQAEVLALAAELKRDPLSHRPL
Mb1684|M.bovis_AF2122/97 --------------MIRHFLRDDDLSPAEQAEVLELAAELKKDPVSRRPL
Rv1656|M.tuberculosis_H37Rv --------------MIRHFLRDDDLSPAEQAEVLELAAELKKDPVSRRPL
MLBr_01410|M.leprae_Br4923 MGGASRLRGRGAAQLTRHFLRDDDLSPTEQADILALAADLKKAPFSRRPL
MMAR_2466|M.marinum_M --------------MIRHFLRDDDLSPAEQAEVLQLAAELKREPFSRRPL
MUL_1648|M.ulcerans_Agy99 --------------MIRHFLRDDDLSPTEQAEVLQLAAELKREPFSRRPL
MAV_3114|M.avium_104 -------------MTPRHFLRDDDLSPAEQAEVLALAAELKKDPFSARPL
*********:* ***::* *** **: .* ***
Mflv_3526|M.gilvum_PYR-GCK EGPRGVAVIFEKNSTRTRFSFEMGIAQLGGHAVVVDGRSTQLGREETLED
Mvan_3310|M.vanbaalenii_PYR-1 EGPRGVAVIFEKNSTRTRFSFEMGIAELGGHAVVVDGRSTQLGREETLED
MSMEG_3772|M.smegmatis_MC2_155 EGPRGVAVIFEKNSTRTRFSFEMGIAQLGGHAIVVDGRSTQLGREETLED
MAB_2340|M.abscessus_ATCC_1997 EGPHGVAVIFEKNSTRTRFSFEMGIAQLGGHAVVVDSRTTQLGREETLED
TH_1596|M.thermoresistible__bu EGPRGVAVIFDKNSTRTRFSFEIGIAQLGGHAVVVDGNTTQLGRDETLHD
Mb1684|M.bovis_AF2122/97 QGPRGVAVIFDKNSTRTRFSFELGIAQLGGHAVVVDSGSTQLGRDETLQD
Rv1656|M.tuberculosis_H37Rv QGPRGVAVIFDKNSTRTRFSFELGIAQLGGHAVVVDSGSTQLGRDETLQD
MLBr_01410|M.leprae_Br4923 AGPRGVAVIFDKNSTRTRFSFDIGIAQLGGHAVVVDGLSTQLGRDETLQD
MMAR_2466|M.marinum_M DGPRGVAVIFDKNSTRTRFSFEMGIAQLGGHAVVVDGRSTQLGREETLPD
MUL_1648|M.ulcerans_Agy99 DGPRGVAVIFDKNSTRTRFSFEMGIAQLGGHAVVVDGRSTQLGREETLPD
MAV_3114|M.avium_104 EGPRGVAVLFDKNSTRTRFSFEVGIAQLGGHAVVVDARSTQLGRDETLED
**:****:*:**********::***:*****:***. :*****:*** *
Mflv_3526|M.gilvum_PYR-GCK TGAVLSRYVDAIVWRTFAQERLTAMASGASVPIVNALSDEFHPCQVLADL
Mvan_3310|M.vanbaalenii_PYR-1 TGQVLSRYVDAIVWRTFAQERLTAMASGSTVPIINALSDEFHPCQVLADL
MSMEG_3772|M.smegmatis_MC2_155 TGAVLSRYVDAIVWRTFAQERLTAMASGASVPIVNALSDEFHPCQVLADL
MAB_2340|M.abscessus_ATCC_1997 TGQVLSRYVEAIVWRTYAQERLTAMASGASVPIVNALSDDFHPCQVLADL
TH_1596|M.thermoresistible__bu TGKVLSRYVEAIVWRTFGQDRLIEMAAGATVPVVNALSDEFHPCQVLADL
Mb1684|M.bovis_AF2122/97 TAKVLSRYVDAIVWRTFGQERLDAMASVATVPVINALSDEFHPCQVLADL
Rv1656|M.tuberculosis_H37Rv TAKVLSRYVDAIVWRTFGQERLDAMASVATVPVINALSDEFHPCQVLADL
MLBr_01410|M.leprae_Br4923 TARVLSGYVDAIVWRTFGQHRLDAMAATATVPVVNALSDEFHPCQVLADL
MMAR_2466|M.marinum_M TAKVLSRFVDAIVWRTFGQDRLQAMASTATVPVVNALSDEFHPCQVLADL
MUL_1648|M.ulcerans_Agy99 TAKVLSRFVDAIVWRTFGQDRLQAMASTATVPVVNALSDEFHPCQVLADL
MAV_3114|M.avium_104 TARVLSRYVEAIVWRTFEQHRLEAMAGAATVPVINALSDEFHPCQVLADL
*. *** :*:******: *.** **. ::**::*****:**********
Mflv_3526|M.gilvum_PYR-GCK QTLIERKGSLKGLRLAYFGDGANNMAHSLMLGGVTAGVDVTIAAPRGFEP
Mvan_3310|M.vanbaalenii_PYR-1 QTLAERKGDLKGLRLTYFGDGANNMAHSLMLGGVTAGIHVTIAAPRGFEP
MSMEG_3772|M.smegmatis_MC2_155 QTLAERKGKLAGLRMTYFGDGANNMAHSLMLGGVTAGVHVTIAAPDGFEP
MAB_2340|M.abscessus_ATCC_1997 QTLAERKGSLDGLRLTYLGDGANNMAHSLMLGGVTAGIHVTIAAPNGFAP
TH_1596|M.thermoresistible__bu QTLAERKGSLAGLRLTYLGDGANNMAHSLLLGGVTAGIHVTIAAPAGFAP
Mb1684|M.bovis_AF2122/97 QTIAERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVAAPEGFLP
Rv1656|M.tuberculosis_H37Rv QTIAERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVAAPEGFLP
MLBr_01410|M.leprae_Br4923 QTIAERKGSLNGLRLSYFGDGANNMAHSLMLGAVTAGVHVTVATPVGFTP
MMAR_2466|M.marinum_M QTITERRGSLKGLRLSYFGDGANNMAHSLMLGGVTAGMHVTVAAPDGFHP
MUL_1648|M.ulcerans_Agy99 QTITERRGSLKGLRLSYFGDGANNMAHSLMLGGVTAGMHVTIAAPDGFHP
MAV_3114|M.avium_104 QAIAEHKGSLSGLRMCYLGDGANNMAHSLMLGGVTAGIHVTIAAPDGFTP
*:: *::* * ***: *:***********:**.****:.**:*:* ** *
Mflv_3526|M.gilvum_PYR-GCK HPMFIAAAETRAHQTGATVAVIDDPLRAADGADVLVTDTWTSMGQENDGL
Mvan_3310|M.vanbaalenii_PYR-1 HPMFVAAAETRAHRTGATVTLTDDPVRAADGVDVLVTDTWTSMGQENDGL
MSMEG_3772|M.smegmatis_MC2_155 DPRFVDAARRRAAETGATVALTKDAKAGADGADVLVTDTWTSMGQENDGL
MAB_2340|M.abscessus_ATCC_1997 HAKYVAEAEKVAATTGASVSVTADPRSAVARADVLVTDAWTSMGQENDGL
TH_1596|M.thermoresistible__bu DPEVVAAAEQRARRTGATIAMTDDPRRGAAGADVLVTDTWTSMGQEDDGR
Mb1684|M.bovis_AF2122/97 DPSVRAAAERRAQDTGASVTVTADAHAAAAGADVLVTDTWTSMGQENDGL
Rv1656|M.tuberculosis_H37Rv DPSVRAAAERRAQDTGASVTVTADAHAAAAGADVLVTDTWTSMGQENDGL
MLBr_01410|M.leprae_Br4923 DPSVLAAAKKRAEATGASVTVTVDADTAAAGADVLVTDTWTSMGQENDGL
MMAR_2466|M.marinum_M DPSVVGAAEQRAETTGASVRLTADAHVAAAGADVLVTDTWTSMGQEDDGL
MUL_1648|M.ulcerans_Agy99 DPSVVGAAEQRAETTGASVRLTADAHVAAAGADVLVTDTWTSMGQEDDGL
MAV_3114|M.avium_104 APEFVAAARRRAESTGATVTLTTDARTAARGVDVLVTDTWTSMGQEDDGL
. *. * ***:: : *. .. .******:*******:**
Mflv_3526|M.gilvum_PYR-GCK DRVRPFRPFQVNADLLGRADSEAVVLHCLPAHRGHEITDEVIDGPRSAVW
Mvan_3310|M.vanbaalenii_PYR-1 DRVRPFRPFQVNADMLAHADSEAVVLHCLPAHRGHEITDDVIDGPQSAVW
MSMEG_3772|M.smegmatis_MC2_155 DRVRPFRPFQVNADLLELADPAAVVLHCLPAHRGHEITDEVIDGPQSAVF
MAB_2340|M.abscessus_ATCC_1997 DRVRPFRAFQVNEDLLALADSEAVVLHCLPAHRGHEITDGVIDGPRSAVW
TH_1596|M.thermoresistible__bu DRVRPFRPFQLNADLLGEADPEAVVLHCLPAHRGHEITDEVIDGPQSAVW
Mb1684|M.bovis_AF2122/97 DRVKPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDGPASAVW
Rv1656|M.tuberculosis_H37Rv DRVKPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDGPASAVW
MLBr_01410|M.leprae_Br4923 DRVKPFWPFQVNARLVGLADSEAIVLHCLPAHRGDEITNEVMDGPTSAIW
MMAR_2466|M.marinum_M DRVKPFRPFQVNEQLLAAADSEAVVLHCLPAHRGDEITDQVMDGPASAVW
MUL_1648|M.ulcerans_Agy99 DRVKPFRPFQVNEQLLAAADSEVVVLHCLPAHRGDEITDQVMDGPASAVW
MAV_3114|M.avium_104 DRRTPFWPYQLNADLVSLADPEAIVLHCLPAHRGEEITDEVMDGPSSVVW
** ** .:*:* :: **. .:**********.***: *:*** *.::
Mflv_3526|M.gilvum_PYR-GCK DEAENRLHAQKALLVWLLERS-
Mvan_3310|M.vanbaalenii_PYR-1 DEAENRLHAQKALLAWLLERA-
MSMEG_3772|M.smegmatis_MC2_155 DEAENRLHAQKALLVWLLEKR-
MAB_2340|M.abscessus_ATCC_1997 DEAENRLHAQKALLVWLLENRR
TH_1596|M.thermoresistible__bu DEAENRLHAQKALLTWLLERRR
Mb1684|M.bovis_AF2122/97 DEAENRLHAQKALLVWLLERS-
Rv1656|M.tuberculosis_H37Rv DEAENRLHAQKALLVWLLERS-
MLBr_01410|M.leprae_Br4923 DEAENRLHAQKALLVWLLER--
MMAR_2466|M.marinum_M DEAENRLHAQKALLVWLLERGR
MUL_1648|M.ulcerans_Agy99 DEAENRLHAQKALLVWLLERGR
MAV_3114|M.avium_104 DEAENRLHAQKALLTWLLERQA
**************.****.