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M. bovis AF2122 / 97 Mb1681 (argJ)

annotation: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein
coordinates: 1852017 - 1853231
length: 404

VTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGPDYAAAGVFTRNQVKAAPVLWTQQ
VLTTGRLRAVILNSGGANACTGPAGFADTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLL
AGVAHVVHEMHGGLVGGDEAAHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPSLATMLCVLTTDAA
AEPAALERALRRAAAATFDRLDIDGSCSTNDTVLLLSSGASEIPPAQADLDEAVLRVCDDLCAQLQADAE
GVTKRVTVTVTGAATEDDALVAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFNGAA
VCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVEENSAYSS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1681argJ-100% (404)bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3529argJ0.085.14% (397) bifunctional ornithine acetyltransferase/N-acetylglutamate
M. tuberculosis H37RvRv1653argJ0.0100.00% (404) bifunctional ornithine acetyltransferase/N-acetylglutamate
M. leprae Br4923MLBr_01407argJ0.082.43% (404) bifunctional ornithine acetyltransferase/N-acetylglutamate
M. abscessus ATCC 19977MAB_2337argJ1e-17775.74% (404) bifunctional ornithine acetyltransferase/N-acetylglutamate
M. marinum MMMAR_2463argJ0.086.14% (404) glutamate N-acetyltransferase ArgJ
M. avium 104MAV_3117argJ0.083.91% (404) bifunctional ornithine acetyltransferase/N-acetylglutamate
M. smegmatis MC2 155MSMEG_3775argJ0.082.07% (396) bifunctional ornithine acetyltransferase/N-acetylglutamate
M. thermoresistible (build 8)TH_1594argJ8e-7178.40% (162) Probable Glutamate n-acetyltransferase argJ
M. ulcerans Agy99MUL_1645argJ0.085.89% (404) bifunctional ornithine acetyltransferase/N-acetylglutamate
M. vanbaalenii PYR-1Mvan_3313argJ0.085.39% (397) bifunctional ornithine acetyltransferase/N-acetylglutamate

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3529|M.gilvum_PYR-GCK          ---------MTRMLRTQGVTAPAGFRAAGIAAGIKASGKLDLALVFNEGP
Mvan_3313|M.vanbaalenii_PYR-1       ---------MTRLLRTQGVTAPAGFRATGIAAGIKASGKLDLALVFNEGP
Mb1681|M.bovis_AF2122/97            ---MTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGP
Rv1653|M.tuberculosis_H37Rv         ---MTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGP
MMAR_2463|M.marinum_M               ---MTEVVSAGRLLRSQGITAPAGFRAAGIAAGIKASGARDLALVFNEGP
MUL_1645|M.ulcerans_Agy99           ---MTEVVSAGRLLRSQGITAPAGFRAAGIAAGIKASGARDLALVFNEGP
MLBr_01407|M.leprae_Br4923          MTKIVEIVNETRLLRAQGVTAPAGFQAAGITAGIKVSGAPDLALVFNEGP
MAV_3117|M.avium_104                ---MTETVNAARLLREQGVTAPAGFRAAGIAAGIKASGKRDLALVFNEGP
MSMEG_3775|M.smegmatis_MC2_155      --------MDAKLVRTQGVTAPAGFRATGIAAGIKASGALDLALVFNEGP
TH_1594|M.thermoresistible__bu      --------------------------------------------------
MAB_2337|M.abscessus_ATCC_1997      ---MTNETVISRLVRTQGVTAPAGFKAAGISAGIKASGKPDLALIFNEGP
                                                                                      

Mflv_3529|M.gilvum_PYR-GCK          DHSAAAVFTRNKIKAAPVLWTQQVLTTGRLRAVILNSGGANACTGPGGFQ
Mvan_3313|M.vanbaalenii_PYR-1       DYAAAGVFTRNKVKAAPVLWSQQVLTTGRLRAVILNSGGANACTGPGGFQ
Mb1681|M.bovis_AF2122/97            DYAAAGVFTRNQVKAAPVLWTQQVLTTGRLRAVILNSGGANACTGPAGFA
Rv1653|M.tuberculosis_H37Rv         DYAAAGVFTRNQVKAAPVLWTQQVLTTGRLRAVILNSGGANACTGPAGFA
MMAR_2463|M.marinum_M               DYSAAGVFTRNQVKAAPVLWTQQALTTGQLRAVILNSGGANACTGPGGFQ
MUL_1645|M.ulcerans_Agy99           DYSAAGVFTRNQVKAAPVLWTQQALTTGQLRAVILNSGGANACTGPGGFQ
MLBr_01407|M.leprae_Br4923          DYAAAGVFTRNKVKAAPVLWTQRVLSTGQLRAVILNSGGANACTGPAGFQ
MAV_3117|M.avium_104                DYGAAGVFTRNKVKAAPVLWSQQVVTTGALRAVILNSGGANACTGPGGFQ
MSMEG_3775|M.smegmatis_MC2_155      DHNAAGVFTRNQIKAAPVQWSQQVLTTGNLRAVILNSGGANACTGALGFQ
TH_1594|M.thermoresistible__bu      --------------------------------------------------
MAB_2337|M.abscessus_ATCC_1997      DYAAAGVFTRNKVKAAPVLWSQQVLTTGRLRAVILNSGGANACTGPQGFQ
                                                                                      

Mflv_3529|M.gilvum_PYR-GCK          DTHATAEAVAAALSAWGTETGAIEVAVCSTGLIGDRLPMDKVSAGVREIV
Mvan_3313|M.vanbaalenii_PYR-1       DTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKVLAGVQEIV
Mb1681|M.bovis_AF2122/97            DTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVV
Rv1653|M.tuberculosis_H37Rv         DTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVV
MMAR_2463|M.marinum_M               DTHATAEAVAAALSDWGTETGAVEVAVCSTGLIGDRLPMDKVLAGVEHIV
MUL_1645|M.ulcerans_Agy99           DTHATAEAVAAALSDWGTETGAVEVAVCSTGLIGDRLPMDKVLAGVEHIV
MLBr_01407|M.leprae_Br4923          DAHTTAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKVLAGVRAIV
MAV_3117|M.avium_104                DAHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVRTIV
MSMEG_3775|M.smegmatis_MC2_155      DAHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKVLAGVTEIV
TH_1594|M.thermoresistible__bu      --------------------------------------------------
MAB_2337|M.abscessus_ATCC_1997      DSHATAEEVAKTLSDWGTQTGAIEVAVCSTGLIGDRLPMDKVLAGVQEIV
                                                                                      

Mflv_3529|M.gilvum_PYR-GCK          QEMAGGLSGGEEAARAIMTTDTVPKQVALHHADNWTVGGMAKGAGMLAPS
Mvan_3313|M.vanbaalenii_PYR-1       HEMAGGLTGGEEAARAIMTTDTVPKQAALHHDDKWTVGGMAKGAGMLAPS
Mb1681|M.bovis_AF2122/97            HEMHGGLVGGDEAAHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPS
Rv1653|M.tuberculosis_H37Rv         HEMHGGLVGGDEAAHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPS
MMAR_2463|M.marinum_M               HELHGGLHGGDDAAHAIMTTDTVAKQVALHHQSKWTVGGMVKGAGMLAPS
MUL_1645|M.ulcerans_Agy99           HELHGGLHGGDDAAHAIMTTDTVAKQVALHHQSKWTVGGMVKGAGMLAPS
MLBr_01407|M.leprae_Br4923          HKMAGGVTGGDDAAHAIMTTDTVPKQVALHNRNKWTVGGMAKGAGMLAPS
MAV_3117|M.avium_104                QDMAGGLSGGDDAAQAIMTTDTVPKQVALHHPGNWTVGGMAKGAGMIAPS
MSMEG_3775|M.smegmatis_MC2_155      HEMAGGLTGGEEAARAIMTTDTVPKQVALHAEN-WTVGGMAKGAGMLAPS
TH_1594|M.thermoresistible__bu      --------------------------------------------------
MAB_2337|M.abscessus_ATCC_1997      HELAGGLGGGTDAAHAIMTTDTVPKEVALHHKDGWTVGAMGKGAGMLAPS
                                                                                      

Mflv_3529|M.gilvum_PYR-GCK          LATMLCVITTDAAAGPEALQSALRNAAARTFDRLDVDGSCSTNDTVLLLS
Mvan_3313|M.vanbaalenii_PYR-1       LATMLTVITTDAVAGPEALDHALRSAAARTFDRLDIDGSCSTNDTVLLLS
Mb1681|M.bovis_AF2122/97            LATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTNDTVLLLS
Rv1653|M.tuberculosis_H37Rv         LATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTNDTVLLLS
MMAR_2463|M.marinum_M               LATMLCVLTTDAVASSAALEQALRRATARTFDRLDIDGSCSTNDTVLLLA
MUL_1645|M.ulcerans_Agy99           LATMLCVLTTDAVASSAALEQALRRATARTFDRLDIDGSCSTNDTVLLLA
MLBr_01407|M.leprae_Br4923          LATMLCVLTTDAVVEPAALDQALRRATAHTFDRLDIDGCCSTNDTVLLLA
MAV_3117|M.avium_104                LATMLCVLTTDAAVDPVALDTALRRATAATFDRLDIDGACSTNDTVLLLA
MSMEG_3775|M.smegmatis_MC2_155      LATMLVVLTTDAVADSAALDTALRRAAAKTFDRLDIDGSCSTNDTVLLLS
TH_1594|M.thermoresistible__bu      ---------------------------------------------VLLLS
MAB_2337|M.abscessus_ATCC_1997      LATMLVVITTDAAVPAEQLDSTLRLATARTFDRLDVDGSCSTNDTVLLLA
                                                                                 ****:

Mflv_3529|M.gilvum_PYR-GCK          SGASEVTPSQAALDEAVLRVCDDLCAQLQADAEGVTKRVLITVTGAESED
Mvan_3313|M.vanbaalenii_PYR-1       SGASEVAPSQQDLDDAVYRVCDDLCTQLQADAEGVTKRVQVTVTGAADED
Mb1681|M.bovis_AF2122/97            SGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATED
Rv1653|M.tuberculosis_H37Rv         SGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATED
MMAR_2463|M.marinum_M               SGASEIAPSQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVKGAATEE
MUL_1645|M.ulcerans_Agy99           SGASEIAPSQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVKGAATEE
MLBr_01407|M.leprae_Br4923          SGASGITPPQADLDDAVRHACDDLCAQLQADAEGVTKRVTVTVIGAASDD
MAV_3117|M.avium_104                SGASAITPAQADLDDAVLRVCDDLCAQLQADAEGVTKRVNVTVTGAASDD
MSMEG_3775|M.smegmatis_MC2_155      SGASEFTPSQDELDAAVLAVCNDLCAQLQADAEGVTKRINITVTGAVSED
TH_1594|M.thermoresistible__bu      SGASEVRPSQEQLDEAVLQVCDDLCRQLQADAEGVTKRVSVTVTGAPSED
MAB_2337|M.abscessus_ATCC_1997      SGASEITPDAAEFAEAVFQVCDDLAAQLQADAEGVTKRILITVTGALSED
                                    **** . *    :  **  .*:**. ************: :** **  ::

Mflv_3529|M.gilvum_PYR-GCK          DAVTAARVIARDSLVKTALFGSDPNWGRVLAAVGMAPVKLDADRISVSFN
Mvan_3313|M.vanbaalenii_PYR-1       DALTAARVIARDSLVKTALFGSDPNWGRVLAAVGMAPVKLDADRITVSFN
Mb1681|M.bovis_AF2122/97            DALVAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFN
Rv1653|M.tuberculosis_H37Rv         DALVAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFN
MMAR_2463|M.marinum_M               DALIAARVIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPNRISVLFN
MUL_1645|M.ulcerans_Agy99           DALIAARVIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPNRISVLFN
MLBr_01407|M.leprae_Br4923          DALVAARMIARDNLVKTAVFGSDPNWGRVLAAVGMAPVALDPDRLCMSFN
MAV_3117|M.avium_104                DAVVAARTIARDSLVKTAVFGSDPNWGRVVAAVGIAPIALDPDRMTVSFN
MSMEG_3775|M.smegmatis_MC2_155      EALVAARAVARDSLVKTALFGSDANWGRVLAAVGIAPVTLDPQRISVSFN
TH_1594|M.thermoresistible__bu      DAVAVARTVARDSLVKTALFGSDPNWGRVLAAVGMSPVTIDPDRILVSFN
MAB_2337|M.abscessus_ATCC_1997      DAVATARVVARDSLVKTALFGSDPNWGRVLAAVGMAPVELDPDRVTVSFN
                                    :*: .** :***.*****:****.*****:****::*: :*.:*: : **

Mflv_3529|M.gilvum_PYR-GCK          GSPVCVDSVGAPGARDVDLSGEEIDVVVDLGVGSGTASIRTTDLSHAYVE
Mvan_3313|M.vanbaalenii_PYR-1       GFPVCVDSVGVPGAREVDLSGEDVTVVVDLGVGSGSASIRTTDLSHAYVE
Mb1681|M.bovis_AF2122/97            GAAVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVE
Rv1653|M.tuberculosis_H37Rv         GAAVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVE
MMAR_2463|M.marinum_M               GSAVCIDGVGAPGAREVDLSATDTYVTVELGVGDAHAAIRTTDLSHAYVE
MUL_1645|M.ulcerans_Agy99           GSAVCIDGVGAPGAGEVDLSATDTYVTVELGVGDAHAAIRTTDLSHAYVE
MLBr_01407|M.leprae_Br4923          GAAVCIDGVGTPCARDVDLSTADIDITVDLRIGDSAATIRTTDLSHTYVE
MAV_3117|M.avium_104                GSAVFADGVGTPGAREVDLSGPDIDITVDLRLGDGRATIRTTDLSHGYVE
MSMEG_3775|M.smegmatis_MC2_155      GSPVCIDGAGAPGAREVDLSGADVDVVIDLASGEHSATVRTTDLSHAYVE
TH_1594|M.thermoresistible__bu      GSPVCIGGVGAPGARAVDLSGEDVDVVVELGLGDGRATVRTTDLSHGYVE
MAB_2337|M.abscessus_ATCC_1997      GNLVCANCTGLPSARQIDLSGPEVEVLIDLGAGDRSATIRTTDLSHAYVE
                                    *  *    .* * *  :***  :  : ::*  *.  * :******* ***

Mflv_3529|M.gilvum_PYR-GCK          ENSAYSS
Mvan_3313|M.vanbaalenii_PYR-1       ENSAYSS
Mb1681|M.bovis_AF2122/97            ENSAYSS
Rv1653|M.tuberculosis_H37Rv         ENSAYSS
MMAR_2463|M.marinum_M               ENSAYSS
MUL_1645|M.ulcerans_Agy99           ENSAYSS
MLBr_01407|M.leprae_Br4923          ENSAYSS
MAV_3117|M.avium_104                ENSAYSS
MSMEG_3775|M.smegmatis_MC2_155      ENSAYSS
TH_1594|M.thermoresistible__bu      ENSAYSS
MAB_2337|M.abscessus_ATCC_1997      ENSAYSS
                                    *******