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MTEVVSAGRLLRSQGITAPAGFRAAGIAAGIKASGARDLALVFNEGPDYSAAGVFTRNQVKAAPVLWTQQ ALTTGQLRAVILNSGGANACTGPGGFQDTHATAEAVAAALSDWGTETGAVEVAVCSTGLIGDRLPMDKVL AGVEHIVHELHGGLHGGDDAAHAIMTTDTVAKQVALHHQSKWTVGGMVKGAGMLAPSLATMLCVLTTDAV ASSAALEQALRRATARTFDRLDIDGSCSTNDTVLLLASGASEIAPSQADLDEAVLRVCDDLCAQLQADAE GVTKRVTVTVKGAATEEDALIAARVIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPNRISVLFNGSA VCIDGVGAPGAGEVDLSATDTYVTVELGVGDAHAAIRTTDLSHAYVEENSAYSS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1645 | argJ | - | 100% (404) | bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1681 | argJ | 0.0 | 85.89% (404) | bifunctional ornithine acetyltransferase/N-acetylglutamate |
| M. gilvum PYR-GCK | Mflv_3529 | argJ | 0.0 | 82.07% (396) | bifunctional ornithine acetyltransferase/N-acetylglutamate |
| M. tuberculosis H37Rv | Rv1653 | argJ | 0.0 | 85.89% (404) | bifunctional ornithine acetyltransferase/N-acetylglutamate |
| M. leprae Br4923 | MLBr_01407 | argJ | 0.0 | 80.69% (404) | bifunctional ornithine acetyltransferase/N-acetylglutamate |
| M. abscessus ATCC 19977 | MAB_2337 | argJ | 1e-175 | 75.00% (404) | bifunctional ornithine acetyltransferase/N-acetylglutamate |
| M. marinum M | MMAR_2463 | argJ | 0.0 | 99.75% (404) | glutamate N-acetyltransferase ArgJ |
| M. avium 104 | MAV_3117 | argJ | 0.0 | 81.44% (404) | bifunctional ornithine acetyltransferase/N-acetylglutamate |
| M. smegmatis MC2 155 | MSMEG_3775 | argJ | 1e-180 | 80.30% (396) | bifunctional ornithine acetyltransferase/N-acetylglutamate |
| M. thermoresistible (build 8) | TH_1594 | argJ | 9e-67 | 76.54% (162) | Probable Glutamate n-acetyltransferase argJ |
| M. vanbaalenii PYR-1 | Mvan_3313 | argJ | 0.0 | 83.33% (396) | bifunctional ornithine acetyltransferase/N-acetylglutamate |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3529|M.gilvum_PYR-GCK ---------MTRMLRTQGVTAPAGFRAAGIAAGIKASGKLDLALVFNEGP
Mvan_3313|M.vanbaalenii_PYR-1 ---------MTRLLRTQGVTAPAGFRATGIAAGIKASGKLDLALVFNEGP
MUL_1645|M.ulcerans_Agy99 ---MTEVVSAGRLLRSQGITAPAGFRAAGIAAGIKASGARDLALVFNEGP
MMAR_2463|M.marinum_M ---MTEVVSAGRLLRSQGITAPAGFRAAGIAAGIKASGARDLALVFNEGP
Mb1681|M.bovis_AF2122/97 ---MTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGP
Rv1653|M.tuberculosis_H37Rv ---MTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGP
MLBr_01407|M.leprae_Br4923 MTKIVEIVNETRLLRAQGVTAPAGFQAAGITAGIKVSGAPDLALVFNEGP
MAV_3117|M.avium_104 ---MTETVNAARLLREQGVTAPAGFRAAGIAAGIKASGKRDLALVFNEGP
MSMEG_3775|M.smegmatis_MC2_155 --------MDAKLVRTQGVTAPAGFRATGIAAGIKASGALDLALVFNEGP
TH_1594|M.thermoresistible__bu --------------------------------------------------
MAB_2337|M.abscessus_ATCC_1997 ---MTNETVISRLVRTQGVTAPAGFKAAGISAGIKASGKPDLALIFNEGP
Mflv_3529|M.gilvum_PYR-GCK DHSAAAVFTRNKIKAAPVLWTQQVLTTGRLRAVILNSGGANACTGPGGFQ
Mvan_3313|M.vanbaalenii_PYR-1 DYAAAGVFTRNKVKAAPVLWSQQVLTTGRLRAVILNSGGANACTGPGGFQ
MUL_1645|M.ulcerans_Agy99 DYSAAGVFTRNQVKAAPVLWTQQALTTGQLRAVILNSGGANACTGPGGFQ
MMAR_2463|M.marinum_M DYSAAGVFTRNQVKAAPVLWTQQALTTGQLRAVILNSGGANACTGPGGFQ
Mb1681|M.bovis_AF2122/97 DYAAAGVFTRNQVKAAPVLWTQQVLTTGRLRAVILNSGGANACTGPAGFA
Rv1653|M.tuberculosis_H37Rv DYAAAGVFTRNQVKAAPVLWTQQVLTTGRLRAVILNSGGANACTGPAGFA
MLBr_01407|M.leprae_Br4923 DYAAAGVFTRNKVKAAPVLWTQRVLSTGQLRAVILNSGGANACTGPAGFQ
MAV_3117|M.avium_104 DYGAAGVFTRNKVKAAPVLWSQQVVTTGALRAVILNSGGANACTGPGGFQ
MSMEG_3775|M.smegmatis_MC2_155 DHNAAGVFTRNQIKAAPVQWSQQVLTTGNLRAVILNSGGANACTGALGFQ
TH_1594|M.thermoresistible__bu --------------------------------------------------
MAB_2337|M.abscessus_ATCC_1997 DYAAAGVFTRNKVKAAPVLWSQQVLTTGRLRAVILNSGGANACTGPQGFQ
Mflv_3529|M.gilvum_PYR-GCK DTHATAEAVAAALSAWGTETGAIEVAVCSTGLIGDRLPMDKVSAGVREIV
Mvan_3313|M.vanbaalenii_PYR-1 DTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKVLAGVQEIV
MUL_1645|M.ulcerans_Agy99 DTHATAEAVAAALSDWGTETGAVEVAVCSTGLIGDRLPMDKVLAGVEHIV
MMAR_2463|M.marinum_M DTHATAEAVAAALSDWGTETGAVEVAVCSTGLIGDRLPMDKVLAGVEHIV
Mb1681|M.bovis_AF2122/97 DTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVV
Rv1653|M.tuberculosis_H37Rv DTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVV
MLBr_01407|M.leprae_Br4923 DAHTTAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKVLAGVRAIV
MAV_3117|M.avium_104 DAHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVRTIV
MSMEG_3775|M.smegmatis_MC2_155 DAHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKVLAGVTEIV
TH_1594|M.thermoresistible__bu --------------------------------------------------
MAB_2337|M.abscessus_ATCC_1997 DSHATAEEVAKTLSDWGTQTGAIEVAVCSTGLIGDRLPMDKVLAGVQEIV
Mflv_3529|M.gilvum_PYR-GCK QEMAGGLSGGEEAARAIMTTDTVPKQVALHHADNWTVGGMAKGAGMLAPS
Mvan_3313|M.vanbaalenii_PYR-1 HEMAGGLTGGEEAARAIMTTDTVPKQAALHHDDKWTVGGMAKGAGMLAPS
MUL_1645|M.ulcerans_Agy99 HELHGGLHGGDDAAHAIMTTDTVAKQVALHHQSKWTVGGMVKGAGMLAPS
MMAR_2463|M.marinum_M HELHGGLHGGDDAAHAIMTTDTVAKQVALHHQSKWTVGGMVKGAGMLAPS
Mb1681|M.bovis_AF2122/97 HEMHGGLVGGDEAAHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPS
Rv1653|M.tuberculosis_H37Rv HEMHGGLVGGDEAAHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPS
MLBr_01407|M.leprae_Br4923 HKMAGGVTGGDDAAHAIMTTDTVPKQVALHNRNKWTVGGMAKGAGMLAPS
MAV_3117|M.avium_104 QDMAGGLSGGDDAAQAIMTTDTVPKQVALHHPGNWTVGGMAKGAGMIAPS
MSMEG_3775|M.smegmatis_MC2_155 HEMAGGLTGGEEAARAIMTTDTVPKQVALHAEN-WTVGGMAKGAGMLAPS
TH_1594|M.thermoresistible__bu --------------------------------------------------
MAB_2337|M.abscessus_ATCC_1997 HELAGGLGGGTDAAHAIMTTDTVPKEVALHHKDGWTVGAMGKGAGMLAPS
Mflv_3529|M.gilvum_PYR-GCK LATMLCVITTDAAAGPEALQSALRNAAARTFDRLDVDGSCSTNDTVLLLS
Mvan_3313|M.vanbaalenii_PYR-1 LATMLTVITTDAVAGPEALDHALRSAAARTFDRLDIDGSCSTNDTVLLLS
MUL_1645|M.ulcerans_Agy99 LATMLCVLTTDAVASSAALEQALRRATARTFDRLDIDGSCSTNDTVLLLA
MMAR_2463|M.marinum_M LATMLCVLTTDAVASSAALEQALRRATARTFDRLDIDGSCSTNDTVLLLA
Mb1681|M.bovis_AF2122/97 LATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTNDTVLLLS
Rv1653|M.tuberculosis_H37Rv LATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTNDTVLLLS
MLBr_01407|M.leprae_Br4923 LATMLCVLTTDAVVEPAALDQALRRATAHTFDRLDIDGCCSTNDTVLLLA
MAV_3117|M.avium_104 LATMLCVLTTDAAVDPVALDTALRRATAATFDRLDIDGACSTNDTVLLLA
MSMEG_3775|M.smegmatis_MC2_155 LATMLVVLTTDAVADSAALDTALRRAAAKTFDRLDIDGSCSTNDTVLLLS
TH_1594|M.thermoresistible__bu ---------------------------------------------VLLLS
MAB_2337|M.abscessus_ATCC_1997 LATMLVVITTDAAVPAEQLDSTLRLATARTFDRLDVDGSCSTNDTVLLLA
****:
Mflv_3529|M.gilvum_PYR-GCK SGASEVTPSQAALDEAVLRVCDDLCAQLQADAEGVTKRVLITVTGAESED
Mvan_3313|M.vanbaalenii_PYR-1 SGASEVAPSQQDLDDAVYRVCDDLCTQLQADAEGVTKRVQVTVTGAADED
MUL_1645|M.ulcerans_Agy99 SGASEIAPSQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVKGAATEE
MMAR_2463|M.marinum_M SGASEIAPSQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVKGAATEE
Mb1681|M.bovis_AF2122/97 SGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATED
Rv1653|M.tuberculosis_H37Rv SGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATED
MLBr_01407|M.leprae_Br4923 SGASGITPPQADLDDAVRHACDDLCAQLQADAEGVTKRVTVTVIGAASDD
MAV_3117|M.avium_104 SGASAITPAQADLDDAVLRVCDDLCAQLQADAEGVTKRVNVTVTGAASDD
MSMEG_3775|M.smegmatis_MC2_155 SGASEFTPSQDELDAAVLAVCNDLCAQLQADAEGVTKRINITVTGAVSED
TH_1594|M.thermoresistible__bu SGASEVRPSQEQLDEAVLQVCDDLCRQLQADAEGVTKRVSVTVTGAPSED
MAB_2337|M.abscessus_ATCC_1997 SGASEITPDAAEFAEAVFQVCDDLAAQLQADAEGVTKRILITVTGALSED
**** . * : ** .*:**. ************: :** ** ::
Mflv_3529|M.gilvum_PYR-GCK DAVTAARVIARDSLVKTALFGSDPNWGRVLAAVGMAPVKLDADRISVSFN
Mvan_3313|M.vanbaalenii_PYR-1 DALTAARVIARDSLVKTALFGSDPNWGRVLAAVGMAPVKLDADRITVSFN
MUL_1645|M.ulcerans_Agy99 DALIAARVIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPNRISVLFN
MMAR_2463|M.marinum_M DALIAARVIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPNRISVLFN
Mb1681|M.bovis_AF2122/97 DALVAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFN
Rv1653|M.tuberculosis_H37Rv DALVAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFN
MLBr_01407|M.leprae_Br4923 DALVAARMIARDNLVKTAVFGSDPNWGRVLAAVGMAPVALDPDRLCMSFN
MAV_3117|M.avium_104 DAVVAARTIARDSLVKTAVFGSDPNWGRVVAAVGIAPIALDPDRMTVSFN
MSMEG_3775|M.smegmatis_MC2_155 EALVAARAVARDSLVKTALFGSDANWGRVLAAVGIAPVTLDPQRISVSFN
TH_1594|M.thermoresistible__bu DAVAVARTVARDSLVKTALFGSDPNWGRVLAAVGMSPVTIDPDRILVSFN
MAB_2337|M.abscessus_ATCC_1997 DAVATARVVARDSLVKTALFGSDPNWGRVLAAVGMAPVELDPDRVTVSFN
:*: .** :***.*****:****.*****:****::*: :*.:*: : **
Mflv_3529|M.gilvum_PYR-GCK GSPVCVDSVGAPGARDVDLSGEEIDVVVDLGVGSGTASIRTTDLSHAYVE
Mvan_3313|M.vanbaalenii_PYR-1 GFPVCVDSVGVPGAREVDLSGEDVTVVVDLGVGSGSASIRTTDLSHAYVE
MUL_1645|M.ulcerans_Agy99 GSAVCIDGVGAPGAGEVDLSATDTYVTVELGVGDAHAAIRTTDLSHAYVE
MMAR_2463|M.marinum_M GSAVCIDGVGAPGAREVDLSATDTYVTVELGVGDAHAAIRTTDLSHAYVE
Mb1681|M.bovis_AF2122/97 GAAVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVE
Rv1653|M.tuberculosis_H37Rv GAAVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVE
MLBr_01407|M.leprae_Br4923 GAAVCIDGVGTPCARDVDLSTADIDITVDLRIGDSAATIRTTDLSHTYVE
MAV_3117|M.avium_104 GSAVFADGVGTPGAREVDLSGPDIDITVDLRLGDGRATIRTTDLSHGYVE
MSMEG_3775|M.smegmatis_MC2_155 GSPVCIDGAGAPGAREVDLSGADVDVVIDLASGEHSATVRTTDLSHAYVE
TH_1594|M.thermoresistible__bu GSPVCIGGVGAPGARAVDLSGEDVDVVVELGLGDGRATVRTTDLSHGYVE
MAB_2337|M.abscessus_ATCC_1997 GNLVCANCTGLPSARQIDLSGPEVEVLIDLGAGDRSATIRTTDLSHAYVE
* * .* * * :*** : : ::* *. * :******* ***
Mflv_3529|M.gilvum_PYR-GCK ENSAYSS
Mvan_3313|M.vanbaalenii_PYR-1 ENSAYSS
MUL_1645|M.ulcerans_Agy99 ENSAYSS
MMAR_2463|M.marinum_M ENSAYSS
Mb1681|M.bovis_AF2122/97 ENSAYSS
Rv1653|M.tuberculosis_H37Rv ENSAYSS
MLBr_01407|M.leprae_Br4923 ENSAYSS
MAV_3117|M.avium_104 ENSAYSS
MSMEG_3775|M.smegmatis_MC2_155 ENSAYSS
TH_1594|M.thermoresistible__bu ENSAYSS
MAB_2337|M.abscessus_ATCC_1997 ENSAYSS
*******