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M. bovis AF2122 / 97 Mb1637 (trpC)

annotation: indole-3-glycerol-phosphate synthase
coordinates: 1795606 - 1796424
length: 272

MSPATVLDSILEGVRADVAAREASVSLSEIKAAAAAAPPPLDVMAALREPGIGVIAEVKRASPSAGALAT
IADPAKLAQAYQDGGARIVSVVTEQRRFQGSLDDLDAVRASVSIPVLRKDFVVQPYQIHEARAHGADMLL
LIVAALEQSVLVSMLDRTESLGMTALVEVHTEQEADRALKAGAKVIGVNARDLMTLDVDRDCFARIAPGL
PSSVIRIAESGVRGTADLLAYAGAGADAVLVGEGLVTSGDPRAAVADLVTAGTHPSCPKPAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1637trpC-100% (272)indole-3-glycerol-phosphate synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3600trpC1e-12684.19% (272) indole-3-glycerol-phosphate synthase
M. tuberculosis H37RvRv1611trpC1e-147100.00% (272) indole-3-glycerol-phosphate synthase
M. leprae Br4923MLBr_01271trpC1e-13690.81% (272) indole-3-glycerol-phosphate synthase
M. abscessus ATCC 19977MAB_2645ctrpC1e-12885.29% (272) indole-3-glycerol-phosphate synthase
M. marinum MMMAR_2413trpC1e-13791.91% (272) indole-3-glycerol phosphate synthase TrpC
M. avium 104MAV_3175trpC1e-13993.38% (272) indole-3-glycerol-phosphate synthase
M. smegmatis MC2 155MSMEG_3219trpC1e-13087.13% (272) indole-3-glycerol-phosphate synthase
M. thermoresistible (build 8)TH_1076trpC1e-12584.64% (267) Probable indole-3-glycerol phosphate synthase trpC
M. ulcerans Agy99MUL_1591trpC1e-13691.54% (272) indole-3-glycerol-phosphate synthase
M. vanbaalenii PYR-1Mvan_2816trpC1e-12885.66% (272) indole-3-glycerol-phosphate synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1637|M.bovis_AF2122/97            MSPATVLDSILEGVRADVAAREASVSLSEIKAAAAAAPPPLDVMAALREP
Rv1611|M.tuberculosis_H37Rv         MSPATVLDSILEGVRADVAAREASVSLSEIKAAAAAAPPPLDVMAALREP
MMAR_2413|M.marinum_M               MSPATVLDSILEGVRADVAAREALVGMTEIKAAAAAAPPPLDVMAALRQP
MUL_1591|M.ulcerans_Agy99           MSPATVLDSILEGVRADVAAREALVGMTEIKAAAAAAPPPLDVMAALRQP
MAV_3175|M.avium_104                MSPATVLDSILEGVRADVAAREALISLSEIKAAAAAAPPPLDVMAALREP
MLBr_01271|M.leprae_Br4923          MCPATVLDSILKGVRADVAAREACISLSEIKAAAAAAPAPLDAMAALREP
Mflv_3600|M.gilvum_PYR-GCK          MGSATVLDSILEGVRADVAAREAVVSLAEVKARAERAPAPLDVMAALRAP
Mvan_2816|M.vanbaalenii_PYR-1       MGSATVLDSIIEGVRADVAAREAAVSMDEVKEQAKRAPAPLDVMAALRAS
MSMEG_3219|M.smegmatis_MC2_155      MSSATVLDSIIEGVRADVAAREAVISLDEIKERAKAAPPPLNVMAALREP
TH_1076|M.thermoresistible__bu      -----VLDSIIEGVRADVAAREAEISLAEIKQRAKDAPPPLDVMAALREP
MAB_2645c|M.abscessus_ATCC_199      MSSGTVLDSILDGVRADVAAREAVVDLATVKAAAKAAPKPLDVMAALREP
                                         *****:.*********** :.:  :*  *  ** **:.***** .

Mb1637|M.bovis_AF2122/97            GIGVIAEVKRASPSAGALATIADPAKLAQAYQDGGARIVSVVTEQRRFQG
Rv1611|M.tuberculosis_H37Rv         GIGVIAEVKRASPSAGALATIADPAKLAQAYQDGGARIVSVVTEQRRFQG
MMAR_2413|M.marinum_M               GIGVIAEVKRASPSAGSLAPITDPAKLARAYEDGGARIISVLTEGRRFQG
MUL_1591|M.ulcerans_Agy99           GIGVIAEVKRASPSAGSLAPITDPAKLARAYEDGGARIISVLTEGRRFQG
MAV_3175|M.avium_104                GIGVIAEVKRASPSAGSLATIADPAKLARAYEDGGARIISVLTEERRFHG
MLBr_01271|M.leprae_Br4923          GIGVIAEVKRASPSVGSLATIADPAKLAQAYEDGGARIISVLTEERRFNG
Mflv_3600|M.gilvum_PYR-GCK          GIAVIAEVKRASPSRGELASIADPAELASAYESGGARAISVLTEQRRFNG
Mvan_2816|M.vanbaalenii_PYR-1       GIAVIAEVKRASPSRGALASIADPAELARAYEDGGARIISVLTEQRRFNG
MSMEG_3219|M.smegmatis_MC2_155      GIGVIAEVKRASPSRGALASIGDPAELAQAYQDGGARVISVLTEQRRFNG
TH_1076|M.thermoresistible__bu      GIAVIAEVKRASPSRGQLAAISDPAKLARAYEDGGARVISVLTEQRRFHG
MAB_2645c|M.abscessus_ATCC_199      GIAVIAEVKRASPSRGALAEISDPAELAKAYEDGGARIISVLTEGRRFNG
                                    **.*********** * ** * ***:** **:.**** :**:** ***:*

Mb1637|M.bovis_AF2122/97            SLDDLDAVRASVSIPVLRKDFVVQPYQIHEARAHGADMLLLIVAALEQSV
Rv1611|M.tuberculosis_H37Rv         SLDDLDAVRASVSIPVLRKDFVVQPYQIHEARAHGADMLLLIVAALEQSV
MMAR_2413|M.marinum_M               SLDDLDAVRAAVSIPLLRKDFVVQPYQIHEARAHGADMLLLIVAALDQSA
MUL_1591|M.ulcerans_Agy99           SLDDLDAVRAAVSIPLLRKDFVVQPYQIHEARAHGADMLLLIVAALDQSA
MAV_3175|M.avium_104                SLDDLDAVRAAVSIPVLRKDFVVQPYQIHEARAHGADMLLLIVAALEQSA
MLBr_01271|M.leprae_Br4923          SLDDLDAVRAAVSVPVLRKDFVVQPYQIHEARAHGADMLLLIVAALDQSA
Mflv_3600|M.gilvum_PYR-GCK          SLDDLDAVRAAVSIPVLRKDFIVRPYQIHEARAHGADLLLLIVAALEQPA
Mvan_2816|M.vanbaalenii_PYR-1       SLDDLDAVRAAVSIPVLRKDFIVRPYQIHEARAHGADMLLLIVAALEQPV
MSMEG_3219|M.smegmatis_MC2_155      SLDDLDAVRAAVSIPVLRKDFIVRPYQIHEARAHGADMLLLIVAALDQPV
TH_1076|M.thermoresistible__bu      SLADLDAVRAAVSVPVLRKDFIIRPYQIHEARAHGADMLLLIVAALEQPA
MAB_2645c|M.abscessus_ATCC_199      SLDDLDSVRAAVSVPVLRKDFVISPYQIHEARAHGADLILLIVAALEQTA
                                    ** ***:***:**:*:*****:: *************::*******:*..

Mb1637|M.bovis_AF2122/97            LVSMLDRTESLGMTALVEVHTEQEADRALKAGAKVIGVNARDLMTLDVDR
Rv1611|M.tuberculosis_H37Rv         LVSMLDRTESLGMTALVEVHTEQEADRALKAGAKVIGVNARDLMTLDVDR
MMAR_2413|M.marinum_M               LVSMLDRTESLGMTALVEVHTEQEADRALKAGAKVIGVNARDLTTLEVDR
MUL_1591|M.ulcerans_Agy99           LVSMLDRTESLGMTALVEVHTEQEADRALKAGAKVIGVNARDLTTLEVDR
MAV_3175|M.avium_104                LVSMLDRTESLGMTALVEVHTEEEADRALRAGAKVIGVNARDLATLEVDR
MLBr_01271|M.leprae_Br4923          LMSMLDRTESLGMIALVEVRTEQEADRALKAGAKVIGVNARDLMTLEVDR
Mflv_3600|M.gilvum_PYR-GCK          LESLLERTESLGMTALVEVHTEEEADRALQAGASLIGVNARNLKTLEVDR
Mvan_2816|M.vanbaalenii_PYR-1       LESLLERTESLGMTALVEVHTEEEADRALQAGASVIGVNARDLKTLEVDR
MSMEG_3219|M.smegmatis_MC2_155      LESLLERTESLGMTALVEVHTEEEADRALKAGASVIGVNARDLKTLEVDR
TH_1076|M.thermoresistible__bu      LESMIERTHSLGMTPLVEVHTEEEADRALQAGAKVIGVNARDLKTLEVHR
MAB_2645c|M.abscessus_ATCC_199      LVSLLDRTESLGMTALVEVHTEEEADRALSAGASVIGVNARDLKTLEIDR
                                    * *:::**.**** .****:**:****** ***.:******:* **::.*

Mb1637|M.bovis_AF2122/97            DCFARIAPGLPSSVIRIAESGVRGTADLLAYAGAGADAVLVGEGLVTSGD
Rv1611|M.tuberculosis_H37Rv         DCFARIAPGLPSSVIRIAESGVRGTADLLAYAGAGADAVLVGEGLVTSGD
MMAR_2413|M.marinum_M               DCFARIAPGLPSNVIRIAESGVRGTNDLLAYAGAGADAVLVGEGLVKSGD
MUL_1591|M.ulcerans_Agy99           DCFARIASGLPSNVIRIAESGVRGTNDLLAYAGAGADAVLVGEGLVKSGD
MAV_3175|M.avium_104                DCFARIAPGLPSNVIRIAESGVRGTGDLLAYAGAGADAVLVGEGLVKSGD
MLBr_01271|M.leprae_Br4923          DCFSRIAPGLPSNVIRIAESGVRGPADLLAYAGAGADAVLVGEGLVKSGD
Mflv_3600|M.gilvum_PYR-GCK          DCFARIAPGLPTNVIKIAESGVRGTADLLAYAGAGADGVLVGEGLVTSGD
Mvan_2816|M.vanbaalenii_PYR-1       DCFARIAPGLPSNVIRVAESGVRGTADLLAYAGAGADAVLVGEGLVTSGD
MSMEG_3219|M.smegmatis_MC2_155      TVFSRIAPGLPSNVIRVAESGVRGTADLLAYAGAGADAVLVGEGLVTSGD
TH_1076|M.thermoresistible__bu      DCFARIAPGLPSDVIRIAESGVRGPADLLAYAGAGADAVLVGEGLVTSGD
MAB_2645c|M.abscessus_ATCC_199      DCFSRIAPGLPSGVIRIAESGVRGTADLLAYAGAGADAVLVGEGLVTSGD
                                      *:***.***:.**::*******. ***********.********.***

Mb1637|M.bovis_AF2122/97            PRAAVADLVTAGTHPSCPKPAR
Rv1611|M.tuberculosis_H37Rv         PRAAVADLVTAGTHPSCPKPAR
MMAR_2413|M.marinum_M               PRAAVADLVTAGTHPSCPKPAR
MUL_1591|M.ulcerans_Agy99           PRAAVADLVTAGTHPSCPKPAR
MAV_3175|M.avium_104                PRAAVADLVTAGTHPSCPKPAR
MLBr_01271|M.leprae_Br4923          PRAAVADLVTAGTHPSCPKPAR
Mflv_3600|M.gilvum_PYR-GCK          PRSAVADLVTAGTHPSCPKPAR
Mvan_2816|M.vanbaalenii_PYR-1       PRSAVADLVTAGAHPSCPKPAR
MSMEG_3219|M.smegmatis_MC2_155      PRSAVADLVTAGTHPSCPKPAR
TH_1076|M.thermoresistible__bu      PRSAVADLVTAGRHPSCPKPAR
MAB_2645c|M.abscessus_ATCC_199      PRGAVADLVTAGTHPSCPKPAR
                                    **.********* *********