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M. bovis AF2122 / 97 Mb1124 (desA2)

annotation: acyl-
coordinates: 1223331 - 1224158
length: 275

MAQKPVADALTLELEPVVEANMTRHLDTEDIWFAHDYVPFDQGENFAFLGGRDWDPSQSTLPRTITDACE
ILLILKDNLAGHHRELVEHFILEDWWGRWLGRWTAEEHLHAIALREYLVVTREVDPVANEDVRVQHVMKG
YRAEKYTQVETLVYMAFYERCGAVFCRNLAAQIEEPILAGLIDRIARDEVRHEEFFANLVTHCLDYTRDE
TIAAIAARAADLDVLGADIEAYRDKLQNVADAGIFGKPQLRQLISDRITAWGLAGEPSLKQFVTG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1124desA2-100% (275)acyl-
M. bovis AF2122 / 97Mb0847cdesA12e-4034.98% (243) acyl-

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2061-1e-12072.99% (274) fatty acid desaturase, type 2
M. tuberculosis H37RvRv1094desA21e-162100.00% (275) acyl-
M. leprae Br4923MLBr_01952desA21e-12878.10% (274) acyl-
M. abscessus ATCC 19977MAB_1237-3e-8958.33% (264) acyl-ACP desaturase DesA2
M. marinum MMMAR_4374desA21e-13885.45% (275) acyl-
M. avium 104MAV_1216-1e-12977.82% (275) Fatty acid desaturase
M. smegmatis MC2 155MSMEG_5248-1e-12276.19% (273) acyl-
M. thermoresistible (build 8)TH_2157desA21e-11671.17% (274) POSSIBLE ACYL-
M. ulcerans Agy99MUL_0187desA21e-13885.45% (275) acyl-
M. vanbaalenii PYR-1Mvan_4653-1e-12676.28% (274) fatty acid desaturase, type 2

CLUSTAL 2.0.9 multiple sequence alignment


Mb1124|M.bovis_AF2122/97            MAQKPVADALTLELEPVVEANMTRHLDTEDIWFAHDYVPFDQGENFAFLG
Rv1094|M.tuberculosis_H37Rv         MAQKPVADALTLELEPVVEANMTRHLDTEDIWFAHDYVPFDQGENFAFLG
MMAR_4374|M.marinum_M               MAQKPVANALTLELEPVVEQNMARHLDTEDIWFAHDFVPFDQGENFAFLG
MUL_0187|M.ulcerans_Agy99           MAQKPVANALTLELEPVVEQNMARHLDTEDIWFAHDFVPFDQGENFAFLG
MAV_1216|M.avium_104                MAERPVANALTLELEPVVEANMDRHLSTEELWFAHDYVPYDRGENFAFLG
MLBr_01952|M.leprae_Br4923          MAQKPVPNALILQLEPVVKDNMARHFANEELWFAHDYVPFDRGENFAFLG
Mflv_2061|M.gilvum_PYR-GCK          MAQKPVANALTLELEPVVLQELRRHLDTEDLWFAHDYVPFDQGENFAFLG
Mvan_4653|M.vanbaalenii_PYR-1       MAQKPVANALTLELEPVVLQELRRHLDTEDVWYAHDYVPFEEGENFAFLG
TH_2157|M.thermoresistible__bu      MAQKPVPNALTLELEPVVQQELRRHIDTEELWYAHEYVPFDQGENFAFLG
MSMEG_5248|M.smegmatis_MC2_155      MAQKPVPNALTLELEPVVAGEMRRHLDSEDLWYAHDYVPFDQGENFAFLG
MAB_1237|M.abscessus_ATCC_1997      MAQKPVPNALTLELTDVVAENIDRHRDTAELWYAHEHVPYDEGENFAFLG
                                    **::**.:** *:*  **  :: **  . ::*:**:.**::.********

Mb1124|M.bovis_AF2122/97            GRDWDPSQSTLPRTITDACEILLILKDNLAGHHRELVEHFILEDW-WGRW
Rv1094|M.tuberculosis_H37Rv         GRDWDPSQSTLPRTITDACEILLILKDNLAGHHRELVEHFILEDW-WGRW
MMAR_4374|M.marinum_M               GRDWDPSQTTLPRLITDACEILLILKDNLAGRHRELVEHFILEDW-WGRW
MUL_0187|M.ulcerans_Agy99           GRDWDPSQTTLPRLITDACEILLILKDNLAGRHRELVEHFILEDW-WGRW
MAV_1216|M.avium_104                GRDWDPSSATLPRPLTDACEIMLLLKDNLAAHHRELVEHFILEDY-WGRW
MLBr_01952|M.leprae_Br4923          GRDWDPSQATLAKAVTDACEILLILKDNLAGYHRELVEHFILEGW-WGRW
Mflv_2061|M.gilvum_PYR-GCK          GRDWEPSDVTLPKPVTDALEILLITKDNLAGYHRELVEHFILEDK-WGRW
Mvan_4653|M.vanbaalenii_PYR-1       GRDWDPSQVTLPKAVTDACEILLITKDNLAGYHRELVEHFILERK-WGRW
TH_2157|M.thermoresistible__bu      GRDWDPSQVTLPRHITDALEILLITKDNLAGYHREIVFSFILENK-WGRW
MSMEG_5248|M.smegmatis_MC2_155      GTDWDPSQVTLPKSITDALEILLITKDNLAGYHRELVEHFILEEQ-WGRF
MAB_1237|M.abscessus_ATCC_1997      GRDWEPSDVKLPKAVVDAVQILLITKDNLAGYHREMVEHFSLEIIPWADF
                                    * **:**. .*.: :.** :*:*: *****. ***:*  * **   *. :

Mb1124|M.bovis_AF2122/97            LGRWTAEEHLHAIALREYLVVTREVDPVANEDVRVQHVMKGYRAEKYTQV
Rv1094|M.tuberculosis_H37Rv         LGRWTAEEHLHAIALREYLVVTREVDPVANEDVRVQHVMKGYRAEKYTQV
MMAR_4374|M.marinum_M               LGRWTAEEHLHAIALREYLVVTREVDPVLNEDVRVQYVMKGYRAEKYTQV
MUL_0187|M.ulcerans_Agy99           LGRWTAEEHLHAIALREYLVVTREVDPVLNEDVRVQYVMKGYRAEKYTQV
MAV_1216|M.avium_104                LGRWTAEEHLHAIALRNYLVVTREVDPTANEEARVQYVMKGYRADTYSQV
MLBr_01952|M.leprae_Br4923          LGRWTAEEHLHAIALREYLVVTREVDPVANEQVRVEHVMKGYRVNSYTQI
Mflv_2061|M.gilvum_PYR-GCK          MGRWTAEEHLHAVALRNCLVVTREIDPSANEDVRVEHVMKGYRADTYSQI
Mvan_4653|M.vanbaalenii_PYR-1       MGRWTAEEHLHAIALRNYLVVTREVDPAANEDVRVEHVMKGYRADTYTQV
TH_2157|M.thermoresistible__bu      IGRWTAEEHLHAVALRNYLVVTREIDPAANEAVRVEHVMKGYRADHYTQI
MSMEG_5248|M.smegmatis_MC2_155      LGRWTAEEHLHAVALRNYLVVTREIDPAANEDVRVEHVMKGYRADRFSQI
MAB_1237|M.abscessus_ATCC_1997      IGRWTAEENLHAIALREYLVVTRNADPNADEDTRLAHVMKGYRADSYSQI
                                    :*******:***:***: *****: **  :* .*: :******.: ::*:

Mb1124|M.bovis_AF2122/97            ETLVYMAFYERCGAVFCRNLAAQIEEPILAGLIDRIARDEVRHEEFFANL
Rv1094|M.tuberculosis_H37Rv         ETLVYMAFYERCGAVFCRNLAAQIEEPILAGLIDRIARDEVRHEEFFANL
MMAR_4374|M.marinum_M               ETLVYMAFYERSLVAFCRNLAAQIEEPVLAGMIDRIGRDEARHELFFANL
MUL_0187|M.ulcerans_Agy99           ETLVYMAFYERSLVAFCRNLAAQIEEPVLAGMIDRIGRDEARHELFFANL
MAV_1216|M.avium_104                ETLVYMAFTERSHAVFCENLSAKLEEPILSGLVDRISRDERRHELFFSNL
MLBr_01952|M.leprae_Br4923          ETLVYMAFLERSYAFFCGSLAAQIKEPALFGLINQIVKDEVRHEEFFANL
Mflv_2061|M.gilvum_PYR-GCK          ETLAFMAMWERAHAVFCRNLEAQIDEPVLKALVGRIARDEERHEQFFANL
Mvan_4653|M.vanbaalenii_PYR-1       ETLAFMALWERAHAVYCRNLEAQITEPVLKALVGRIAKDEERHEEFFANL
TH_2157|M.thermoresistible__bu      ERLAFMSFFERAHAVYCRNLQDQITEPVLKSLLDRIAKDEERHEQFWSNL
MSMEG_5248|M.smegmatis_MC2_155      ETLVFMAFFERSHAVFCRNLQAQITEPVLASLMGRIATDEERHEEFFSNL
MAB_1237|M.abscessus_ATCC_1997      ETLVFNAFFEQMHAVFVQNLAAQTEDAVLKGLLANIEKDERRHEQMYSNI
                                    * *.: :: *:  . :  .*  :  :. * .:: .*  ** *** :::*:

Mb1124|M.bovis_AF2122/97            VTHCLDYTRDETIAAIAARAADLDVLGADIEAYRDKLQNVADAGIFGKPQ
Rv1094|M.tuberculosis_H37Rv         VTHCLDYTRDETIAAIAARAADLDVLGADIEAYRDKLQNVADAGIFGKPQ
MMAR_4374|M.marinum_M               VDHCLATRRDETIAAIAARAGDLQAPGADIDAYQDKLRDVAEAGIFGADQ
MUL_0187|M.ulcerans_Agy99           VDHCLATRRDETIAAIAARAGDLQAPGADIDAYQDKLRDVAEAGIFGADQ
MAV_1216|M.avium_104                VARCLEYTRDETIAAIAARAAELEVPGADIDAYQDKLRNIAEAGVFTEND
MLBr_01952|M.leprae_Br4923          VAHCLECNRDETVAAIAARAAGLDVLGADIDAYHDKVENISAAGIFGSVE
Mflv_2061|M.gilvum_PYR-GCK          VSHCLGYSREETVEAIARRAGELGVVGGDIDAYQYKVAVVAEAGIFDQDH
Mvan_4653|M.vanbaalenii_PYR-1       VAHCLTYTREETVAAIARRAAGLDVVGGDIDAYQDKVATVAEAGIFDRDQ
TH_2157|M.thermoresistible__bu      VAHCLQTHRDETVEAIARRAAELGVVGGDIEPYQDKVANVAKTGIFDEAA
MSMEG_5248|M.smegmatis_MC2_155      VSYVLDKHRDETVEAIAARAAGLDVIGADIAPYQDKVANVAEAGIFDKAA
MAB_1237|M.abscessus_ATCC_1997      VLECLRLHPEDTIAAIKARAAELKVIGADIDGYEDKVATVAEAGIIDGTT
                                    *   *    ::*: **  **. * . *.**  *. *:  :: :*::    

Mb1124|M.bovis_AF2122/97            LRQLISDRITAWGLAGEPSLKQFVTG-
Rv1094|M.tuberculosis_H37Rv         LRQLISDRITAWGLAGEPSLKQFVTG-
MMAR_4374|M.marinum_M               LKQVVSGRITEWGLAEEPALKQFVTG-
MUL_0187|M.ulcerans_Agy99           LKQVVSGRITEWGLAEEPALKQFVTG-
MAV_1216|M.avium_104                LRQVISDRIRAWGVADEPALKPFVIG-
MLBr_01952|M.leprae_Br4923          LRQVISDRITAWGLINEPQLAQFVTS-
Mflv_2061|M.gilvum_PYR-GCK          LRTVIVDRITAWGLAEEPALQQFISS-
Mvan_4653|M.vanbaalenii_PYR-1       LRKVVSDRIAAWGLADEPELKQFISS-
TH_2157|M.thermoresistible__bu      LRTVISDRITAWDLAAEPRLSQFVTSS
MSMEG_5248|M.smegmatis_MC2_155      LQKVISDRITAWGLAGEASLKDFVLA-
MAB_1237|M.abscessus_ATCC_1997      VQDVVRELTDKWGVTDRL---------
                                    :: ::      *.:  .