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M. bovis AF2122 / 97 Mb0823 (pepC)

annotation: putative aminopeptidase 2
coordinates: 894148 - 895449
length: 433

MAATAHGLCEFIDASPSPFHVCATVAGRLLGAGYRELREADRWPDKPGRYFTVRAGSLVAWNAEQSGHTQ
VPFRIVGAHTDSPNLRVKQHPDRLVAGWHVVALQPYGGVWLHSWLDRDLGISGRLSVRDGTGVSHRLVRI
DDPILRVPQLAIHLAEDRKSLTLDPQRHINAVWGVGERVESFVGYVAQRAGVAAADVLAADLMTHDLTPS
ALIGASVNGTASLLSAPRLDNQASCYAGMEALLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDLLS
SVLERIVLAAGGTREDFLRRLTTSMLASADMAHATHPNYPDRHEPSHPIEVNAGPVLKVHPNLRYATDGR
TAAAFALACQRAGVPMQRYEHRADLPCGSTIGPLAAARTGIPTVDVGAAQLAMHSARELMGAHDVAAYSA
ALQAFLSAELSEA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0823pepC-100% (433)putative aminopeptidase 2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1628-0.073.07% (427) putative aminopeptidase 2
M. tuberculosis H37RvRv0800pepC0.099.77% (433) putative aminopeptidase 2
M. leprae Br4923MLBr_02213pepC0.078.52% (433) putative aminopeptidase 2
M. abscessus ATCC 19977MAB_0701-1e-16166.59% (428) putative aminopeptidase 2
M. marinum MMMAR_4891pepC0.079.58% (431) aminopeptidase PepC
M. avium 104MAV_0742-0.083.57% (426) putative aminopeptidase 2
M. smegmatis MC2 155MSMEG_5828-0.074.88% (430) putative aminopeptidase 2
M. thermoresistible (build 8)TH_0570pepC0.075.64% (427) PROBABLE AMINOPEPTIDASE PEPC
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5121-0.074.24% (427) putative aminopeptidase 2

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1628|M.gilvum_PYR-GCK          -----------------MSASPQGLCEFIDASPSPFHACRTAADRLLAAG
Mvan_5121|M.vanbaalenii_PYR-1       -----------------MPASPQGLCEFIDASPSPFHVCRTAAERLLAAG
MSMEG_5828|M.smegmatis_MC2_155      -----------------MAASPHSLCEFIDASPSPFHVCATAAARLRDAG
TH_0570|M.thermoresistible__bu      -----------------MSASAEGLCEFIDASPSPYHVCATVADRLRAAG
Mb0823|M.bovis_AF2122/97            -----------------MAATAHGLCEFIDASPSPFHVCATVAGRLLGAG
Rv0800|M.tuberculosis_H37Rv         -----------------MAATAHGLCEFIDASPSPFHVCATVAGRLLGAG
MAV_0742|M.avium_104                MFTMSGGPRNQTK----SSASAQGLCEFIDASPSPFHVCATVAARLIAAG
MLBr_02213|M.leprae_Br4923          MPTLASTTSSPTAMMLGMPASAADLCEFINASPSPFHVCATVAGRLLDAG
MMAR_4891|M.marinum_M               MSDAPTTS-----------ATARGLGEFIDASPSPFHLCATVARRLLDAG
MAB_0701|M.abscessus_ATCC_1997      -----------------MTATAVGLCQFIDASPSPFHAVDTVAQRLRHEG
                                                       *:. .* :**:*****:*   *.* **   *

Mflv_1628|M.gilvum_PYR-GCK          FTELAESDPWP-AAGDFFAVRAGSLIAWRS-NTDSAAAPFRVVGAHTDSP
Mvan_5121|M.vanbaalenii_PYR-1       FTELSESDPWP-GAGDHFAVRAGSLIAWRS-PDGSRALPFRIVGAHTDSP
MSMEG_5828|M.smegmatis_MC2_155      YTELAETDAWP-AAGRFFTVRAGSLVAWRT-VED-ASAPFRIVGGHTDSP
TH_0570|M.thermoresistible__bu      FVELLERDPWPGAAGDYFTVRAGSLIAWRT-TAD-TGAGFRIVGAHTDSP
Mb0823|M.bovis_AF2122/97            YRELREADRWPDKPGRYFTVRAGSLVAWNAEQSGHTQVPFRIVGAHTDSP
Rv0800|M.tuberculosis_H37Rv         YRELREADRWPDKPGRYFTVRAGSLVAWNAEQSGHTQVPFRIVGAHTDSP
MAV_0742|M.avium_104                YTELDEAKHWPSQPGRYFTVRAGSLVAWNSTGADG---PFRIVGAHTDSP
MLBr_02213|M.leprae_Br4923          YAELSEVERWPDHPGRYFIVRAGSLVAWSAGQGVKAHAPFRIVGAHTDSP
MMAR_4891|M.marinum_M               YTELSEIDRWPQQPGRYFTVRAGSLVAWDSGGVGTAQAPFRIVGAHSDSP
MAB_0701|M.abscessus_ATCC_1997      FTELFEAQRWPGHSGDYFVVRSGSIVAWRGVDMEGEHAAFRVIGAHTDSP
                                    : ** * . **  .* .* **:**::**           **::*.*:***

Mflv_1628|M.gilvum_PYR-GCK          NLRVKQHPDRFLSGWQIVALQPYGGAWLNSWLDRDLGVSGRLSVRD---G
Mvan_5121|M.vanbaalenii_PYR-1       NLRVKQHPDRFVAGWQVVALQPYGGAWLNSWLDRDLGVSGRLSVRD---G
MSMEG_5828|M.smegmatis_MC2_155      NLRVKQRPDRMVAGWQVVALQPYGGAWLNSWLDRDLGISGRLTLRDESAD
TH_0570|M.thermoresistible__bu      NLRVKEHPDRFVAGWRVVALQPYGGVWLNSWLDRDLGLSGRLSVRS---G
Mb0823|M.bovis_AF2122/97            NLRVKQHPDRLVAGWHVVALQPYGGVWLHSWLDRDLGISGRLSVRD---G
Rv0800|M.tuberculosis_H37Rv         NLRVKQHPDRLVAGWHVVALQPYGGVWLHSWLDRDLGISGRLSVRD---G
MAV_0742|M.avium_104                NLRVKQHPDRTVAGWRVVALQPYGGAWLNSWLDRDLGISGRLSVRD---G
MLBr_02213|M.leprae_Br4923          NLRVKQHPDLLVAGWRVVALQPYGGAWLNSWLDRDLGVSGRLSVRSAGKG
MMAR_4891|M.marinum_M               NLRVKQHPDRLVAGWQVVALEPYGGAWLNSWLDRDLGVSGRLSVRAPGVR
MAB_0701|M.abscessus_ATCC_1997      NLRVKANADRVQAGWPMVALEPYGGAWVQTWLDRDLGLSGRVLVRD---G
                                    ***** ..*   :** :***:****.*:::*******:***: :*     

Mflv_1628|M.gilvum_PYR-GCK          NTVRHLLVRVDDPILRVPQLAIHLS--EDRKGVELNPQRHVNAVWGVGGG
Mvan_5121|M.vanbaalenii_PYR-1       NSIRHTLVRVDDPILRVPQLAIHLS--EDRKGVELNPQRHVNAVWGTGTG
MSMEG_5828|M.smegmatis_MC2_155      DGIAHHLVRIDDPILRVPQLAIHLS--DDRKGVSPDPQRHLNGVWGLGER
TH_0570|M.thermoresistible__bu      SGLEHRLIRIDEPVLRVPQLAIHLA--EDRKSVTLNPQQHVNAVWGVADR
Mb0823|M.bovis_AF2122/97            TGVSHRLVRIDDPILRVPQLAIHLA--EDRKSLTLDPQRHINAVWGVGER
Rv0800|M.tuberculosis_H37Rv         TGVSHRLVLIDDPILRVPQLAIHLA--EDRKSLTLDPQRHINAVWGVGER
MAV_0742|M.avium_104                SGLSHRLVRIDEPILRVPQLAIHLA--EDRKSVTLDPQRHVNAVWGVGES
MLBr_02213|M.leprae_Br4923          SEITDRLVRIDDPILRVPQLAIHLA--EDRKSLTLDPQRHVNAVWGVGDK
MMAR_4891|M.marinum_M               GGISHRLVRIDEPILRVPQLAIHLA--EDRKSLTLDPQRHVNAVWGVGAQ
MAB_0701|M.abscessus_ATCC_1997      DAVRSTLIRIDQPILRVPNLAIHMVSAEERKKWVIDPQWHVNSVWSG---
                                      :   *: :*:*:****:****:   ::**    :** *:*.**.    

Mflv_1628|M.gilvum_PYR-GCK          ARSFLGYIAGRAGVTEDDVLGFDLMTHDLAPSRLVGAD----GELVSAPR
Mvan_5121|M.vanbaalenii_PYR-1       ARSFLDFVAGRAGVVGDDVLGFDLMTHDLTPSRLAGVD----DNLVSAPR
MSMEG_5828|M.smegmatis_MC2_155      PGVFIEFVADRAGVDAADVLGFDLMTHDLAPSAVTGAA----GEFVSAPR
TH_0570|M.thermoresistible__bu      DRAFLDHVADHAGVAAADVLGFDLMTHDLAPSQLIGSD----RDLISAPR
Mb0823|M.bovis_AF2122/97            VESFVGYVAQRAGVAAADVLAADLMTHDLTPSALIGASVNGTASLLSAPR
Rv0800|M.tuberculosis_H37Rv         VESFVGYVAQRAGVAAADVLAADLMTHDLTPSALIGASVNGTASLLSAPR
MAV_0742|M.avium_104                ARSFVDYVAARAAVAPDDVLAADLMTHDLTPSTLIGASENGTADLLSAPR
MLBr_02213|M.leprae_Br4923          AGSLLEYVAERTGVAVADVLAVDLMTHDLVPSMVIGAD----ANLLSAPR
MMAR_4891|M.marinum_M               RGSFLGYVAQRAGLAEGDVLAADLMTHDLTPAAVIGAN----ADLLSAPR
MAB_0701|M.abscessus_ATCC_1997      ELGFEEYIAEQLGVSPADVLGRDLMTHDLTGAALVGPD----ESLLSAPR
                                       :  .:* : .:   ***. *******. : : *       .::****

Mflv_1628|M.gilvum_PYR-GCK          LDNQATCYAGLEAFLAAEP----DGVVPVLVLFDHEEVGSQSDHGAQSDL
Mvan_5121|M.vanbaalenii_PYR-1       LDNQATCYAGLEAFLSARAG---ADAVPVLVLFDHEEVGSQSDHGAQSEL
MSMEG_5828|M.smegmatis_MC2_155      LDNQATCYAGLEAFLAAEE----SGYLPVLALFDHEEVGSQSDHGAQSEL
TH_0570|M.thermoresistible__bu      LDNQASCYAGLEALLSVEP----GDHLPVLALFDHEEVGSTSDAGAQSEL
Mb0823|M.bovis_AF2122/97            LDNQASCYAGMEALLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDL
Rv0800|M.tuberculosis_H37Rv         LDNQASCYAGMEALLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDL
MAV_0742|M.avium_104                LDNQASCYAGLEALLATEP----SGPLPVLVLFDHEEVGSSSDHGAQSDL
MLBr_02213|M.leprae_Br4923          LDNQVSCYAGMEALLASVP----HDCLPVLALFDHEEVGSTSDRGARSNL
MMAR_4891|M.marinum_M               LDNQASCYAGLEALLAAES----DQVLPVLAIFDHEEVGSTSDHGAQSNL
MAB_0701|M.abscessus_ATCC_1997      LDNQASCYAGLEAFLAAES-----SSTTVLALFDHEEVGSVSDHGAHSDL
                                    ****.:****:**:*:           .**.:******** *. **:*:*

Mflv_1628|M.gilvum_PYR-GCK          LLTTLERVTLAAGGSREDFLRRLPDSVVASGDMAHATHPNYPERHEPGHL
Mvan_5121|M.vanbaalenii_PYR-1       LLTVLERITLAAGGSREDFLRRLPASMVASGDMAHATHPNYPDRHEPGHL
MSMEG_5828|M.smegmatis_MC2_155      LPTVLERIALAAGQSREDFLRRVAGSMVASGDMAHATHPNYPERHEPGHL
TH_0570|M.thermoresistible__bu      LLTVLERITLAAGGTREDFLRRLPGSMVASGDMAHATHPNYPDRHEPGHL
Mb0823|M.bovis_AF2122/97            LSSVLERIVLAAGGTREDFLRRLTTSMLASADMAHATHPNYPDRHEPSHP
Rv0800|M.tuberculosis_H37Rv         LSSVLERIVLAAGGTREDFLRRLTTSMLASADMAHATHPNYPDRHEPSHP
MAV_0742|M.avium_104                LSTVLERIVLAAGGTREDYLSRLPASLLASADMAHATHPNYPERHEPGHP
MLBr_02213|M.leprae_Br4923          LSTVLERIVLAAGGGRDDYLRRLPASLLVSADMAHATHPNYPECHEPSHL
MMAR_4891|M.marinum_M               LNTVLERIVLAGGGVREDLLRLLPASLLASADMAHATHPNYPERHEPSHQ
MAB_0701|M.abscessus_ATCC_1997      LSTVLERIVLSSNGTREDFLRRAAASLMVSADMAHATHPNYPDRHEPGHQ
                                    * :.***:.*:..  *:* *   . *::.*.***********: ***.* 

Mflv_1628|M.gilvum_PYR-GCK          IEVNAGPVLKVQPNLRYATDGRTAATFALACAQAGVNLQRYEHRADLPCG
Mvan_5121|M.vanbaalenii_PYR-1       IEVNAGPVLKVQPNLRYATDGRTAAAFALACAQAGVNLQRYEHRADLPCG
MSMEG_5828|M.smegmatis_MC2_155      IEVNAGPVLKVQPNLRYATDGRTAAAFALACDQAGVPLQRYEHRADLPCG
TH_0570|M.thermoresistible__bu      IEVNGGPVLKVQPNLRYATDGRTAAAFALACQQAGVPLQRYEHRADLPCG
Mb0823|M.bovis_AF2122/97            IEVNAGPVLKVHPNLRYATDGRTAAAFALACQRAGVPMQRYEHRADLPCG
Rv0800|M.tuberculosis_H37Rv         IEVNAGPVLKVHPNLRYATDGRTAAAFALACQRAGVPMQRYEHRADLPCG
MAV_0742|M.avium_104                IAVNAGPVLKVHPNLRYATDSRTAAAFALACRQAGVTLQRYEHRADLPCG
MLBr_02213|M.leprae_Br4923          IEVNAGPVLKVHPNLRYATDGRTAAAFEVACQQAGVRLQRYEHRADRPCG
MMAR_4891|M.marinum_M               IAVNAGPVLKVHPNLRYATEGRTAAAFALACQQAGVNLQRYEHRADLPCG
MAB_0701|M.abscessus_ATCC_1997      IAVNAGPVIKIHPNVRYATDGRGAAAFALACERAGVPVQRYEHRADMQCG
                                    * **.***:*::**:****:.* **:* :** :*** :********  **

Mflv_1628|M.gilvum_PYR-GCK          STIGPMTAANTGIPTVDVGAAQLAMHSAREVMGAGDVADYSAALQAFLSP
Mvan_5121|M.vanbaalenii_PYR-1       STIGPMTAANTGIPTVDVGAAQLAMHSAREVMGAADVADYSAALAAFLSP
MSMEG_5828|M.smegmatis_MC2_155      STIGPMTAARTGIPTVDVGAAQLAMHSAREFMGAHDVAAYSAALQAFLSP
TH_0570|M.thermoresistible__bu      STIGPMTSARTGIPTVDVGAPQLAMHSARELMGAADVTSYSAALRAFLSP
Mb0823|M.bovis_AF2122/97            STIGPLAAARTGIPTVDVGAAQLAMHSARELMGAHDVAAYSAALQAFLSA
Rv0800|M.tuberculosis_H37Rv         STIGPLAAARTGIPTVDVGAAQLAMHSARELMGAHDVAAYSAALQAFLSA
MAV_0742|M.avium_104                STIGPLAAARTGIPTVDVGAAQLAMHSARELMGAHDVAAYSAAMHAFLSP
MLBr_02213|M.leprae_Br4923          STIGPLASARTGIPTVDVGAAQLAMHSARELMGAHDVAVYSAALQAFFSA
MMAR_4891|M.marinum_M               STIGPMTSARTGIPTVDVGAAQLAMHSARELMGAADVAAYSAALRAFYAP
MAB_0701|M.abscessus_ATCC_1997      STIGPFAASHTGITTVDVGAATLAMHSVRELMGAHDVPMYADALQAFLEL
                                    *****::::.***.******. *****.**.*** **. *: *: **   

Mflv_1628|M.gilvum_PYR-GCK          V----
Mvan_5121|M.vanbaalenii_PYR-1       G----
MSMEG_5828|M.smegmatis_MC2_155      A----
TH_0570|M.thermoresistible__bu      A----
Mb0823|M.bovis_AF2122/97            ELSEA
Rv0800|M.tuberculosis_H37Rv         ELSEA
MAV_0742|M.avium_104                G----
MLBr_02213|M.leprae_Br4923          DLF--
MMAR_4891|M.marinum_M               E----
MAB_0701|M.abscessus_ATCC_1997      PATS-