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M. bovis AF2122 / 97 Mb0648c (recC)

annotation: exonuclease V gamma chain
coordinates: 726258 - 729551
length: 1097

MALHLHRAERTDLLADGLGALLADPQPDPFAQELVLVAARGVERWLSQRLSLVLGCGPGRADGVCAGIAF
RNPQSLIAEITGTLDDDPWSPEALAWPLLAVIDASLDEPWCRTLASHLGHFATTDAEAELRRGRRYSVAR
RLAGLFASYARQRPGLLAAWLDGDLGELPGDLAWQPPLWRALVTTVGADPPHVRHDKTIARLRDGPADLP
ARLSLFGHTRLACTDVQLLDALAVHHDLHLWLPHPSDELWRALAGFQGADGLLPRRQDTSRRAAQHPLLE
TLGRDVRELQRALPAARATDEFLGATTKPDTLLGWLQADIAGNAPRPAERSLSDADRSVQVHACHGPARQ
IDVLREVLLGLLEDDPTLQPRDIVVMCPDIDTYAPLIVAGFGLGEVAGDCHPAHRLRVRLADRALTQTNP
LLSVAAELLTIAETRATASQLLNLAQAAPVRAKFGFADDDLDTITTWVRESNIRWGFDPTHRRRYGLDTV
VHNTWRFGLDRILTGVAMSEDSQAWLDTALPLDDVGSNRVELAGRLAEFVERLHHVVGGLSGARPLVAWL
DALATGIDLLTACNDGWQRAQVQREFADVLARAGSRAAPLLRLPDVRALLDAQLAGRPTRANFRTGTLTV
CTMVPMRSVPHRVVCLVGLDDGVFPRLSHPDGDDVLAREPMTGERDIRSEDRQLLLDAIGAATQTLVITY
TGADERTGQPRPPAVPLAELLDALDQTTSAPVRERILVTHPLQPFDRKNVTPGALLGAKPFTFDPAALAA
AQAAAGKRCPPTAFISGRLPAPPAADVTLADLLDFFKDPVKGFFRALDYTLPWDVDTVEDSIPVQVDALA
EWTVGERMLRDMLRGLHLDDAAHSEWRRGTLPPGRLGVRRAKEIRNRARDLAAAALAHRDGHGQAHDVDV
DLGDGRRLSGTVTPVFGGRTVSVTYSKLAPKHVLPAWIGLVTLAAQEPGREWSALCIGRSKTRNHIARRL
FVPPPDPVAVLRELVLLYDAGRREPLPLPLKTSCAWAQARRDGQDPYPPARECWQTNRFRPGDDDAPAHV
RAWGPRAPFEVLLGKPRAGEEVAGEETRLGALAARLWLPLLAAEGSV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0648crecC-100% (1097)exonuclease V gamma chain

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5129-0.064.40% (1101) exodeoxyribonuclease V, gamma subunit
M. tuberculosis H37RvRv0631crecC0.099.82% (1097) exonuclease V gamma chain
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0400c-0.066.21% (1095) exodeoxyribonuclease V, gamma subunit (RecC)
M. marinum MMMAR_0958recC0.068.06% (1102) exodeoxyribonuclease V (gamma chain), RecC
M. avium 104MAV_4542recC0.070.13% (1098) exodeoxyribonuclease V, gamma subunit
M. smegmatis MC2 155MSMEG_1328recC0.066.64% (1106) exodeoxyribonuclease V, gamma subunit
M. thermoresistible (build 8)TH_1754recC0.067.00% (1112) PROBABLE EXONUCLEASE V (GAMMA CHAIN) RECC
M. ulcerans Agy99MUL_0709recC0.067.79% (1102) exodeoxyribonuclease V (gamma chain), RecC
M. vanbaalenii PYR-1Mvan_1210-0.065.97% (1099) exodeoxyribonuclease V, gamma subunit

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0958|M.marinum_M               --MPLHLHRAERTDLLADGLGALLAQPLADPFAEELVLVPARGVERWLSQ
MUL_0709|M.ulcerans_Agy99           --MPFHLHRAERTDLLADGLGALLAQPLADPFAEELVLVPARGVERWLSQ
MAV_4542|M.avium_104                --MPLHLHRAERTDLLADGLGALLANPPADPFALELVVVPARGVERWLSQ
MAB_0400c|M.abscessus_ATCC_199      --MALHLRRAERTDMLADGLARLLAVPAPDPFAEELVLVPAKGIERWLSQ
MSMEG_1328|M.smegmatis_MC2_155      MSMALHLHRAERTDLLADGLAALLSDPLPDPFATELVLVPAKGVERWLSQ
TH_1754|M.thermoresistible__bu      --MALHLHRAERTDQLADGLAALLSEPLDDPFVEELVIVPAKGVERWLSQ
Mflv_5129|M.gilvum_PYR-GCK          --MALHLHRADRTDLLADGLGAMLSDPPADPFAEDLVLVSARGTERWLSQ
Mvan_1210|M.vanbaalenii_PYR-1       --MALHLHRADRTDLLADGLGAMLADPPADPFAEDLVLVSARGTERWLSQ
Mb0648c|M.bovis_AF2122/97           --MALHLHRAERTDLLADGLGALLADPQPDPFAQELVLVAARGVERWLSQ
Rv0631c|M.tuberculosis_H37Rv        --MALHLHRAERTDLLADGLGALLADPQPDPFAQELVLVAARGVERWLSQ
                                      *.:**:**:*** *****. :*: *  ***. :**:*.*:* ******

MMAR_0958|M.marinum_M               RLSHLLG-HAPGGGDGVCAGVSFRNPRSLIAEITG----TAADDPWSAEA
MUL_0709|M.ulcerans_Agy99           RLSHLLG-HAPGGGDGVCAGVSFRNPRSLIAEITG----TAADDPWSAEA
MAV_4542|M.avium_104                RLSHVLG-RARDG-DGVCAGVQFRSPGSLIAEITG----TAEDDPWSPDA
MAB_0400c|M.abscessus_ATCC_199      RLSDRLG---------VCAGVRFRSPRSLIAEITG----TVDNDPWSPDA
MSMEG_1328|M.smegmatis_MC2_155      RLSNRLG---------VCAAVEFRNPRSLIAELTG----TADDDPWSPDA
TH_1754|M.thermoresistible__bu      RLSHLLGRGADGNSDGVCAGVAFRNPHSLIAGLTGPLTGAADDDPWAPEA
Mflv_5129|M.gilvum_PYR-GCK          RLSHVLG--RGSGQDGICAGVTFRHPRSLIAELTG----TREHDPWSPDA
Mvan_1210|M.vanbaalenii_PYR-1       RLSHILG--RGSGQDGICAGVTFRHPRSLMAELTG----TDEDDPWSPDA
Mb0648c|M.bovis_AF2122/97           RLSLVLG-CGPGRADGVCAGIAFRNPQSLIAEITG----TLDDDPWSPEA
Rv0631c|M.tuberculosis_H37Rv        RLSLVLG-CGPGRADGVCAGIAFRNPQSLIAEITG----TLDDDPWSPEA
                                    ***  **         :**.: ** * **:* :**    :  .***:.:*

MMAR_0958|M.marinum_M               MTWPLLEVIDGSLEQPWCATLARHLGHFDV-GPEAELRRGRRYSVARRLA
MUL_0709|M.ulcerans_Agy99           MTWPLLEVIDGSLEEPWCATLARHLGHFDV-GPEAELRRGRRYSVARRLA
MAV_4542|M.avium_104                LAWPLLEAIDCSLDEPWCRTLATHLGHFHS-GAEAELRRTRRYEAARRLA
MAB_0400c|M.abscessus_ATCC_199      LVWPLLTVIDENLHQSWAVPLASHLGAFEA-GEERELRQGRRYAVARRLA
MSMEG_1328|M.smegmatis_MC2_155      MVWPLLGVIDESLDEPWCATLATHLGHFEM-GEEYELRQGRRYAVARRLA
TH_1754|M.thermoresistible__bu      MVWPLLEVIDASCTEDWCSTLATHLGHFET-GAERELRQGRRYAVARRLA
Mflv_5129|M.gilvum_PYR-GCK          MVWPLLAVIDDCLAEPWCSTLGAHLGHFAD-GEERELRQGRRYAVARRLA
Mvan_1210|M.vanbaalenii_PYR-1       MVWPLLDVIDGCITEPWCATLATHLGHFAD-GEEKVLRQGRRYAVARRLA
Mb0648c|M.bovis_AF2122/97           LAWPLLAVIDASLDEPWCRTLASHLGHFATTDAEAELRRGRRYSVARRLA
Rv0631c|M.tuberculosis_H37Rv        LAWPLLAVIDASLDEPWCRTLASHLGHFATTDAEAELRRGRRYSVARRLA
                                    :.**** .**    : *. .*. *** *   . *  **: *** .*****

MMAR_0958|M.marinum_M               GLFASYARQRPRVLSDWLDGGRGDLDPDLSWQPELWCALVAVVGADPPHL
MUL_0709|M.ulcerans_Agy99           GLFASYARQRPRVLSDWLDGGRGDLDPDLSWQPELWCALVAVVGADPPHL
MAV_4542|M.avium_104                GLFAGYARQRPRLLVDWLDGDPGDLDEDLRWQPPLWRALVARVAADPPHV
MAB_0400c|M.abscessus_ATCC_199      GLFASYARQRPELLVSWLDGDP--AEPDLAWQPPLWRALVARVDAVPPHV
MSMEG_1328|M.smegmatis_MC2_155      GLFASYARQRPQLLVDWDG-----LPDDLAWQKALWQALCERIDADPPHI
TH_1754|M.thermoresistible__bu      GLFASYARQRPQLLIDWLAGEVGDLDSDLRWQPPLWRALVDRVDADPPHV
Mflv_5129|M.gilvum_PYR-GCK          GLFASYATQRPRLLEDWLAGRTDGLDADLRWQPELYRALVDRVQADPPHV
Mvan_1210|M.vanbaalenii_PYR-1       GLFDSYARQRPQLLIDWIDGRTGALDEDLRWQPELYRALLAHVDTEPPHI
Mb0648c|M.bovis_AF2122/97           GLFASYARQRPGLLAAWLDGDLGELPGDLAWQPPLWRALVTTVGADPPHV
Rv0631c|M.tuberculosis_H37Rv        GLFASYARQRPGLLAAWLDGDLGELPGDLAWQPPLWRALVTTVGADPPHV
                                    *** .** *** :*  *          ** **  *: **   : : ***:

MMAR_0958|M.marinum_M               RHEKTLTALRARP-AGLPPRLSLFGHTRMAVTDIELLGAVATHHELHLWL
MUL_0709|M.ulcerans_Agy99           RHEKTLTALRARP-AGLPPRLSLFGHTRMAVTDIELLGALATHHELHLWL
MAV_4542|M.avium_104                RHAETIARLRRAP-SDLPQRLSLFGHTRLACTDVELLDALATHHDLHLWL
MAB_0400c|M.abscessus_ATCC_199      RHDRVRARLREAP-SDLPPRISLFGHTRLPVTDIELLDALATHHDLYLWL
MSMEG_1328|M.smegmatis_MC2_155      RHAKTLVQLHESP-TDLPQRLSLFGHTRLPATEVELLTALATHHDLHLWL
TH_1754|M.thermoresistible__bu      RHAEVLARLRESPVEELPPRLSLFGHTRLPSTEIELLEALATHHELHLWL
Mflv_5129|M.gilvum_PYR-GCK          RHAETVARLVDSP-TDLPERLSLFGHTRLPVTEIELLAAVATHHDLHLWL
Mvan_1210|M.vanbaalenii_PYR-1       RHAETVARLRESP-SELPQRLSMFGHTRLPATEIELLAALSTHHDLHLWL
Mb0648c|M.bovis_AF2122/97           RHDKTIARLRDGP-ADLPARLSLFGHTRLACTDVQLLDALAVHHDLHLWL
Rv0631c|M.tuberculosis_H37Rv        RHDKTIARLRDGP-ADLPARLSLFGHTRLACTDVQLLDALAVHHDLHLWL
                                    ** .. . *   *   ** *:*:*****:. *:::** *::.**:*:***

MMAR_0958|M.marinum_M               PHPSAALWRSLADLH---GVVPRRADASHRRVVHPLLATLGRDLRELQRG
MUL_0709|M.ulcerans_Agy99           PHPSAALWRSLADLH---GVVPRRADASHRRVVHPLLATLGRDLRELQRG
MAV_4542|M.avium_104                PHPSDRLWRALAGTN---GVIPRRDDTSHRAVAHPLLATLGRDLRELQRG
MAB_0400c|M.abscessus_ATCC_199      PHPSDALWQTLASDH---GPVPRREDIAHRSVRHPLLATLGRDVRELQRA
MSMEG_1328|M.smegmatis_MC2_155      PHPSDTLWQALSTRK---GPLPRREDTSHRDVGHPLLATLGRDLREMQRL
TH_1754|M.thermoresistible__bu      PHPSNELWTRLAGHT---GPVPRRADLTHREVGHPLLATLGRDLRELQRS
Mflv_5129|M.gilvum_PYR-GCK          PHPSDALWTSLRDVR---DVIPRRDDTSHRRVGHPLLATLGRDLRELQRC
Mvan_1210|M.vanbaalenii_PYR-1       PHPSDKLWTSLRGVH---GAAPRRTDTSHRDVDHPLLATLGRDLRELQRV
Mb0648c|M.bovis_AF2122/97           PHPSDELWRALAGFQGADGLLPRRQDTSRRAAQHPLLETLGRDVRELQRA
Rv0631c|M.tuberculosis_H37Rv        PHPSDELWRALAGFQGADGLLPRRQDTSRRAAQHPLLETLGRDVRELQRA
                                    ****  **  *       .  *** * ::* . **** *****:**:** 

MMAR_0958|M.marinum_M               LPADPATDEALGA------TTRPDTLLGWLQSDLAANQVRPENRTLVAGD
MUL_0709|M.ulcerans_Agy99           LPADPATDEALGA------TTRPDTLLGWLQSDLAANQVRPENRTLVAGD
MAV_4542|M.avium_104                LPADPRTDEYLAG------DARPDTLLGWLQSDIAANAIRPVGRSLAAGD
MAB_0400c|M.abscessus_ATCC_199      LP-EPTSDEYLSG------TTFSDSLLGWLQSDLAADEVRPQGRALAAHD
MSMEG_1328|M.smegmatis_MC2_155      LP-EPDTDEFRGR------SEYPDTLLGWLQSDIAADAVRPQGRHHRRED
TH_1754|M.thermoresistible__bu      LPAERATDEFLGAPGPETDAGRPDTLLGWLQSDIAANAVRPAGRVLRPDD
Mflv_5129|M.gilvum_PYR-GCK          LPTDTVSDESLGS------VARPDTLLGWLQSDIGADRVRAEGRTHDAGD
Mvan_1210|M.vanbaalenii_PYR-1       LPADAQTDESLGP------ADRPDTLLGWLQSDLGADAVRPQGRSCAPGD
Mb0648c|M.bovis_AF2122/97           LPAARATDEFLGA------TTKPDTLLGWLQADIAGNAPRPAERSLSDAD
Rv0631c|M.tuberculosis_H37Rv        LPAARATDEFLGA------TTKPDTLLGWLQADIAGNAPRPAGRSLSDAD
                                    **    :**  .          .*:******:*:..:  *.  *     *

MMAR_0958|M.marinum_M               RSIQVHSCHGPARQIDVLREVLLGLLADDPTLEPRDILVMCPDIETYAPL
MUL_0709|M.ulcerans_Agy99           RSIQVHSCHGPARQIDVLREVLLGLLADDPTLEPRDILVMCPDIETYAPL
MAV_4542|M.avium_104                RSVQIHNCHGPARQVDVLREVLLGLLADDPTLQPRDILVMCPDIESYAPL
MAB_0400c|M.abscessus_ATCC_199      HTVQVHSCHGPARQIDVLREVLLGLLADDPTLEPRDILVMCPDIETYAPL
MSMEG_1328|M.smegmatis_MC2_155      RSIQVHSCHGPSRQIDVLREVLLGLLADDPTLEPRDILVMCPDIETYAPL
TH_1754|M.thermoresistible__bu      DSVQVHSCHGAARQIDVLREVLLGLLAEDETLEPRDIVVMCPDIETYAPL
Mflv_5129|M.gilvum_PYR-GCK          RSVQVHSCHGPARQVDVLREVLLGMLEDDPTLEPRDILVMCPDIEAYAPL
Mvan_1210|M.vanbaalenii_PYR-1       RSVQVHSCHGAARQIDVLREVLLGLLADDPTLEPRDILVMCPDIETYAPL
Mb0648c|M.bovis_AF2122/97           RSVQVHACHGPARQIDVLREVLLGLLEDDPTLQPRDIVVMCPDIDTYAPL
Rv0631c|M.tuberculosis_H37Rv        RSVQVHACHGPARQIDVLREVLLGLLEDDPTLQPRDIVVMCPDIDTYAPL
                                     ::*:* ***.:**:*********:* :* **:****:******::****

MMAR_0958|M.marinum_M               IVADFGLGDVMH---------GVHPAHRLRVRLADRSLLQTNPLLGVASQ
MUL_0709|M.ulcerans_Agy99           IVADFGLGDVMH---------GVHPAHRLRVRLADRSLLQTNPLLGVASQ
MAV_4542|M.avium_104                IMADFGLGDVVH---------GAHPAHQLRVRLADRSLIQTNPLLGVAAQ
MAB_0400c|M.abscessus_ATCC_199      ISARFGLGESVP---------GAHPAHQLRVRLADRALVQTNPLLTVAGQ
MSMEG_1328|M.smegmatis_MC2_155      ITAGFGLGDVVPRTRGAHINLSAHPAHKLRVRLADRALVQTNPLLAVAAQ
TH_1754|M.thermoresistible__bu      IMADFGLGDVVH---------GAHPAHRLRVRLADRALVQTNPLLGVAAQ
Mflv_5129|M.gilvum_PYR-GCK          IVAGFGLGDVVS---------GAHPAHRLRVKLADRALTQTNPLLGVARR
Mvan_1210|M.vanbaalenii_PYR-1       IVAGFGLGDVVS---------GAHPAHRLRVTLADRALTQTNPLLGVARQ
Mb0648c|M.bovis_AF2122/97           IVAGFGLGEVAG---------DCHPAHRLRVRLADRALTQTNPLLSVAAE
Rv0631c|M.tuberculosis_H37Rv        IVAGFGLGEVAG---------DCHPAHRLRVRLADRALTQTNPLLSVAAE
                                    * * ****:            . ****:*** ****:* ****** ** .

MMAR_0958|M.marinum_M               LLMLAGSRVTASEVLNLAQAAPVRARFGFADDHLEDITRWVRQSNIRWGF
MUL_0709|M.ulcerans_Agy99           LLMLAGSRVTASEVLNLAQAAPVRARFGFADDHLEDITRWVRQSNIRWGF
MAV_4542|M.avium_104                LLALAGGRVRASEVLNLAQTPAVRARFGFTDDDLEAITGWVRQANIRWGL
MAB_0400c|M.abscessus_ATCC_199      ILSLASGRATASEVLNLAESSPVRMRFGFTDDDLDAITAWVREANIRWGF
MSMEG_1328|M.smegmatis_MC2_155      LLALAGGRATASEVLNLAESAPVRARFGFTDDDLDAITAWTREANIRWGF
TH_1754|M.thermoresistible__bu      LLQLAGGRATAGEVLNLAQAAPVRARFGFTDDDLEDITRWVRQANIRWGF
Mflv_5129|M.gilvum_PYR-GCK          LLELAGSRATAGEVLDVAEAAPVRARFGFSDDDLDAVGTWVRESNIRWGF
Mvan_1210|M.vanbaalenii_PYR-1       LLGLAGGRATASEVLNLAEAAPVRLRFGFTDDDLDAIGDWVREANIRWGF
Mb0648c|M.bovis_AF2122/97           LLTIAETRATASQLLNLAQAAPVRAKFGFADDDLDTITTWVRESNIRWGF
Rv0631c|M.tuberculosis_H37Rv        LLTIAETRATASQLLNLAQAAPVRAKFGFADDDLDTITTWVRESNIRWGF
                                    :* :*  *. *.::*::*::..** :***:**.*: :  *.*::*****:

MMAR_0958|M.marinum_M               DQEHRKPYGVD-FVHNTWRFGIDRVLAGVAMSEASHAWIDATLPLDDVGS
MUL_0709|M.ulcerans_Agy99           DQEHRKPYGVD-FVHNTWRFGIDRVLAGVAMSEASHAWIDATLPLDDVGS
MAV_4542|M.avium_104                DRQHRRPYHVD-FVHNTWRFGIDRILAGVAMSDDSNAWIDATLPLDDVSS
MAB_0400c|M.abscessus_ATCC_199      DPEHRAPYGVD-FLHNTWRFGIDRVLAGVALSEDAHAWLGATLPLDDVSS
MSMEG_1328|M.smegmatis_MC2_155      DQEHRRPYGVE-FLHNTWRFGIDRVLAGVAMSDDSHAWLGTTLPLDDVSS
TH_1754|M.thermoresistible__bu      DTEHRRPFGVE-FIQNTWRFGVDRVLAGVAMSDDAHSWVGTTLPLDDVSS
Mflv_5129|M.gilvum_PYR-GCK          DRDHRRPYGVD-FVQNTWRFGIDRVLAGVAMSDDSRAWLDTTLPLDDVSS
Mvan_1210|M.vanbaalenii_PYR-1       DRGHRHPYGVD-FVQNTWRFGIDRVLAGVAMSDDSHAWLDTTLPLDDVSS
Mb0648c|M.bovis_AF2122/97           DPTHRRRYGLDTVVHNTWRFGLDRILTGVAMSEDSQAWLDTALPLDDVGS
Rv0631c|M.tuberculosis_H37Rv        DPTHRRRYGLDTVVHNTWRFGLDRILTGVAMSEDSQAWLDTALPLDDVGS
                                    *  **  : :: .::******:**:*:***:*: :.:*:.::******.*

MMAR_0958|M.marinum_M               NRVELAGRFAEYIDRLRQVVDSLTGTRPLREWLAALTDGIALLTRVDEGD
MUL_0709|M.ulcerans_Agy99           NRVELAGRFAEYIDRLRQVVDSLTGTRPLREWLAALTDGIALLTRVDEGE
MAV_4542|M.avium_104                NRVQLAGQLAEFVARLQHVLDSLTGARPLTEWLTAVADGIALLTRVRDAD
MAB_0400c|M.abscessus_ATCC_199      NRVELAGRFAEFVSQLHTTVTALSGTRPLAEWLTILSTGIDALATDSED-
MSMEG_1328|M.smegmatis_MC2_155      NRVELAGRFADFVEKLRRTVDQLSGTRPLHEWLDALTAGIDALALADED-
TH_1754|M.thermoresistible__bu      NRVELAGRLAEYVERLHRTVGALTGTQPLHAWLTALTEGVDLLTRVDDED
Mflv_5129|M.gilvum_PYR-GCK          NRVELAGRLAEFVDRLRDAVESLTGTAMLADWLARIRTGVSELTAVPDSD
Mvan_1210|M.vanbaalenii_PYR-1       NRVELAGRLAEYVDRLRSVVESLSGAAALNDWLARLSEGLDALTAVSDAD
Mb0648c|M.bovis_AF2122/97           NRVELAGRLAEFVERLHHVVGGLSGARPLVAWLDALATGIDLLTACNDG-
Rv0631c|M.tuberculosis_H37Rv        NRVELAGRLAEFVERLHHVVGGLSGARPLVAWLDALATGIDLLTACNDG-
                                    ***:***::*::: :*: .:  *:*:  *  **  :  *:  *:   :  

MMAR_0958|M.marinum_M               AWQSDQMQREFAEVSRTAGRWVETMLRLPDIRALLQRHLAGRPTRANFRT
MUL_0709|M.ulcerans_Agy99           AWQSDQMRREFAEVSRTAGRWVETMLRVPDIRALLQRHLAGRPTRANFRT
MAV_4542|M.avium_104                EWQSGQLQREFAAVSAQAGSRADTVLRLPDVRALLTRHLSGRPTRANFRT
MAB_0400c|M.abscessus_ATCC_199      -WPRAQMLREFAEIQDAA---VPVSLRLSDIRALLDRHLAGRPTRANFRT
MSMEG_1328|M.smegmatis_MC2_155      -WPAAQMQREFAEITARAGD-TATSLRLADVRALLDRHLAGRPTRANFRT
TH_1754|M.thermoresistible__bu      AWQVSQLHREFGDILAKAGPRADMPLRLPDITALLERQLAGRPTRANFRT
Mflv_5129|M.gilvum_PYR-GCK          LWQHSQLERELADIAAAAGVHAGTELRLSDVRSLLDRHLAGRPTRANFRT
Mvan_1210|M.vanbaalenii_PYR-1       LWQTSQVGRELADILAAAGAHADVELRLSDIRALLDRHLAGRPTRANFRT
Mb0648c|M.bovis_AF2122/97           -WQRAQVQREFADVLARAGSRAAPLLRLPDVRALLDAQLAGRPTRANFRT
Rv0631c|M.tuberculosis_H37Rv        -WQRAQVQREFADVLARAGSRAAPLLRLPDVRALLDAQLAGRPTRANFRT
                                     *   *: **:. :   *   .   **:.*: :**  :*:**********

MMAR_0958|M.marinum_M               GTLTVCTMVPMRSVPHRVVCLVGLDDGVFPRQGVVDGDDVLARSPMTGER
MUL_0709|M.ulcerans_Agy99           GTLTVCTMVPMRSVPHRVVCLVGLDDGVFPRQGVVDGDDVLARSPMTGER
MAV_4542|M.avium_104                GTLTVCTMVPMRSVPHRVVCLVGLDDGLFPRLGVVDGDDALSRCPMTGER
MAB_0400c|M.abscessus_ATCC_199      GTLTVCTMVPMRSVPHRVVCLVGLDDGVFPRLGAVDGDDALARDPMTGER
MSMEG_1328|M.smegmatis_MC2_155      GTLTVCTMVPMRSVPHRVVCLVGLDDGVFPRLGAVDGDDALARDPMTGER
TH_1754|M.thermoresistible__bu      GTLTVCTMVPMRSVPHRVVCLVGLDDGVFPRVGVVDGDDVLARDPMTGER
Mflv_5129|M.gilvum_PYR-GCK          GTLTVCTMVPMRSVPHRVVCLVGLDDGVFPRVGVVDGDDALARDPMTGER
Mvan_1210|M.vanbaalenii_PYR-1       GTLTVCTMVPMRSVPHRVVCLVGLDDGVFPRSGVVDGDDVLARDPMTGER
Mb0648c|M.bovis_AF2122/97           GTLTVCTMVPMRSVPHRVVCLVGLDDGVFPRLSHPDGDDVLAREPMTGER
Rv0631c|M.tuberculosis_H37Rv        GTLTVCTMVPMRSVPHRVVCLVGLDDGVFPRLSHPDGDDVLAREPMTGER
                                    ***************************:*** .  ****.*:* ******

MMAR_0958|M.marinum_M               DIRSEDRQLLLDAIGAATENLVITYTGANEYSGQRKPPAVPLAELLDTLD
MUL_0709|M.ulcerans_Agy99           DIRSEDRQLLLDAIGAATENLVITYTGANEYSGQRKPPAVPLAELLGTLD
MAV_4542|M.avium_104                DIRSEDRQLLLDAIGAATEKLVITYTGANEYSGQPRPPAVPLAELLDTLD
MAB_0400c|M.abscessus_ATCC_199      DIRSEDRQLLLDAIGAATETLVLTYTGANEYSGQARPPAVPLAELLDTLD
MSMEG_1328|M.smegmatis_MC2_155      DIRSEDRQLLLDAILAATQTLVITYTGANEYSGQARPPAVPLAELIDTLK
TH_1754|M.thermoresistible__bu      DVRSEDRQLLLDAICAATEKLVITYTGANEYSGQVRPPAVPLAELLDTLD
Mflv_5129|M.gilvum_PYR-GCK          DIRSEDRQLLLDAIGAATEKLVITYTGANEYSGQRRPPAVPVVELLDTLD
Mvan_1210|M.vanbaalenii_PYR-1       DIRSEDRQLLLDAIGAATEKLVITYTGANEYSGQRKPPAVPVMELLDTLD
Mb0648c|M.bovis_AF2122/97           DIRSEDRQLLLDAIGAATQTLVITYTGADERTGQPRPPAVPLAELLDALD
Rv0631c|M.tuberculosis_H37Rv        DIRSEDRQLLLDAIGAATQTLVITYTGADERTGQPRPPAVPLAELLDALD
                                    *:************ ***:.**:*****:* :** :*****: **:.:*.

MMAR_0958|M.marinum_M               MTTTEQVRGRVVVEHPLQPFDVRNVTCGALMP--GVPFSFDPTVLRAARA
MUL_0709|M.ulcerans_Agy99           MTTTEQVRGRVVVEHPLQPFDVRNVTRGALMP--GVPFSFDPTVLRAARA
MAV_4542|M.avium_104                ITTAEPVRDRIVVRHPLQPFDIRNVIPDELVP--GVPFSFDPTVLRAARA
MAB_0400c|M.abscessus_ATCC_199      ITTSQPVRDRIHITHPLQPFDIRNVTPGSVIP--GHPFTFDSTALIAARA
MSMEG_1328|M.smegmatis_MC2_155      ITTEDSALD-VLTRHPLQPFDKRNVIPGALVP--DEPFTFDQTALVAARA
TH_1754|M.thermoresistible__bu      RTTEEPVRDRLVVQHPLQPFDVRNVEPGGLIP--GVPFTFDSTVLNAARI
Mflv_5129|M.gilvum_PYR-GCK          VTTSSPVRDRVHTSHPLQPFDIANVTPGELGMPVGTPFTFDPTTLTAARA
Mvan_1210|M.vanbaalenii_PYR-1       VTTSAPVRETVLVEHPLQPFDVDNVTPGKLGMPAGRPFTFDPTALTAATA
Mb0648c|M.bovis_AF2122/97           QTTSAPVRERILVTHPLQPFDRKNVTPGALLG--AKPFTFDPAALAAAQA
Rv0631c|M.tuberculosis_H37Rv        QTTSAPVRERILVTHPLQPFDRKNVTPGALLG--AKPFTFDPAALAAAQA
                                     **   .   :   *******  **  . :      **:** :.* **  

MMAR_0958|M.marinum_M               AAGERAQQPRFIGAPLAPPPADDVALADLVAFFKDPVKGFFRALDYTLPW
MUL_0709|M.ulcerans_Agy99           AAGERAQQPRFIGAPLAPPPADDVALADLVAFFKDPVKGFFRALDYTLPW
MAV_4542|M.avium_104                ATGEHCEPPKFISAPLPPPPPADVILADLVGFFKDPVQGFFRALQFTLPH
MAB_0400c|M.abscessus_ATCC_199      AAGARAERPPFICGPLPALDVTDVALTDLAAFFNHPIKGFFRALDYTLPW
MSMEG_1328|M.smegmatis_MC2_155      SSGERAMRPAFFSDPLPPPLPDDVALEDLLNFFKDPVKGFFRALDYTLPW
TH_1754|M.thermoresistible__bu      RAEDRAARPPFVSGPLAPPPPEDVLLADLLAFFRDPVKGFFRALDYTLPW
Mflv_5129|M.gilvum_PYR-GCK          TTGDREEHRPLLAEPLPAPPADDVALDDLIGFFRDPVKGFFRALDFTLPW
Mvan_1210|M.vanbaalenii_PYR-1       AAGHRGPRPHLLGRPLPAPPPADVALDELIGFFKDPVKGFFRALDYTLPW
Mb0648c|M.bovis_AF2122/97           AAGKRCPPTAFISGRLPAPPAADVTLADLLDFFKDPVKGFFRALDYTLPW
Rv0631c|M.tuberculosis_H37Rv        AAGKRCPPTAFISGRLPAPPAADVTLADLLDFFKDPVKGFFRALDYTLPW
                                     :  :     :.   *..    ** * :*  **..*::******::*** 

MMAR_0958|M.marinum_M               DVDGVEDAMPVDINALEEWTVGDRMLADILSGMAPDEARQAEWRRGTLPP
MUL_0709|M.ulcerans_Agy99           DVDGVEDAMPVDINALEEWTVGDRMLADILSGMAPDEARQAEWRRGTLPP
MAV_4542|M.avium_104                DVDGVQDAMPVDIDALQEWTVGDRMLRDMLRGMTPEDARQAEWRRGTLPP
MAB_0400c|M.abscessus_ATCC_199      DVDGVSDDMPVEIDALEEWTVGDRLLADMLRGMTPADAQQAEWRRGTLPP
MSMEG_1328|M.smegmatis_MC2_155      DVEGVSDVMPVDIDALEEWTVGDRMLSDILRGMTPAAAQQAEWRRGTLPP
TH_1754|M.thermoresistible__bu      EVDGVDDAMPVDLDALAEWTVGDRMLDDLLRGMRPEDARDAEWRRGTLPP
Mflv_5129|M.gilvum_PYR-GCK          DVDGLDDAIPVDVDALQEWKIGQRLLDDMQRGMSPAQAQQAEWRRGSLPP
Mvan_1210|M.vanbaalenii_PYR-1       DVEAVEDAMPVEIDALQEWKIGDRMLDDMLRGMTPADAQQAEWRRGSLPP
Mb0648c|M.bovis_AF2122/97           DVDTVEDSIPVQVDALAEWTVGERMLRDMLRGLHLDDAAHSEWRRGTLPP
Rv0631c|M.tuberculosis_H37Rv        DVDTVEDSIPVQVDALAEWTVGERMLRDMLRGLHPDDAAHSEWRRGTLPP
                                    :*: :.* :**:::** **.:*:*:* *:  *:    * .:*****:***

MMAR_0958|M.marinum_M               GQLGWRKVTEIRDQAALLAAAALRHRRAD-AAAYDVDIDLG-SRRLTGTV
MUL_0709|M.ulcerans_Agy99           GQLGWRKVTEIRDQAALLAAAAMRHRRDD-AAAYDVDIDLG-SRRLTGTV
MAV_4542|M.avium_104                GQLGWRRVTEIRDQAARLAREAHQHRAEQPGGAHDVDIDLGRGRRLTGTV
MAB_0400c|M.abscessus_ATCC_199      GQLGWRRVSELRERCAALAAETRGYQTDD-SRAFDIDIDLGDGRRLAGTV
MSMEG_1328|M.smegmatis_MC2_155      GQLGWRRAIALRDQCALLAAEALGFRDTD-GQAYDVDIDLGGGRRLTGTV
TH_1754|M.thermoresistible__bu      GRLGWRKAGEILDQAVELARTAHQYRDEP-PRACDVDIDLGGGRRLTGTV
Mflv_5129|M.gilvum_PYR-GCK          GRLGWRRAQEITTRSAALAAAAQQYRTPD-PHAVDIDVAVGPARRLTGTV
Mvan_1210|M.vanbaalenii_PYR-1       GRLGWRKAQEIASRSAALAAAARQHRTPD-PRAIDVDVAIGPARRVTGTV
Mb0648c|M.bovis_AF2122/97           GRLGVRRAKEIRNRARDLAAAALAHRDGH-GQAHDVDVDLGDGRRLSGTV
Rv0631c|M.tuberculosis_H37Rv        GRLGVRRAKEIRNRARDLAAAALAHRDGH-GQAHDVDVDLGDGRRLSGTV
                                    *:** *:.  :  :.  **  :  .:      * *:*: :* .**::***

MMAR_0958|M.marinum_M               AQVFGDRLVSVTYSKLDGKHLLESWIPLLALFAHAGAHDWSAVCIGRQKR
MUL_0709|M.ulcerans_Agy99           AQVFGDRLVSVTYSKLDGKHLLESWIPLLALFAHAGAHDWSAVCIGRQKR
MAV_4542|M.avium_104                TPVYGNRLVAVTYSRLDGRHLLESWIPLLALAAHDRGRDWSAVCIGRMRR
MAB_0400c|M.abscessus_ATCC_199      SPVFGERLVSVTYSRLDAKHLLQSWIPLVALSAHDHQRDWSAVCIGRARR
MSMEG_1328|M.smegmatis_MC2_155      SPVFGDRLVSVTYSKLGGKHLLQSWIPLLALAAGYPDRDWLAVCIGRPAR
TH_1754|M.thermoresistible__bu      APVFGQRLVSVTYSKLDGRHLLQPWISLLALYAHDPHTAWSAVCVGRRKR
Mflv_5129|M.gilvum_PYR-GCK          PRLYGERMVAVTYSKLAGRHLLESWIRLVALTAHRPGTDWTAVCIGRGDR
Mvan_1210|M.vanbaalenii_PYR-1       PRVYGSRTVAVTYSKLDGRHLLASWIRLVALTAHHPGTDWTAVCIGRGGR
Mb0648c|M.bovis_AF2122/97           TPVFGGRTVSVTYSKLAPKHVLPAWIGLVTLAAQEPGREWSALCIGR-SK
Rv0631c|M.tuberculosis_H37Rv        TPVFGGRTVSVTYSKLAPKHVLPAWIGLVTLAAQEPGREWSALCIGR-SK
                                    . ::* * *:****:*  :*:* .** *::* *      * *:*:**  :

MMAR_0958|M.marinum_M               GTVPRQAGLGRPREQPVELLRDLVAIYDAGRREPIPLPIKTSYAWGAARH
MUL_0709|M.ulcerans_Agy99           GTVPRQAGLGRPRGQPVELLRDLVAIYDAGRREPIPLPIKTSYAWAAARH
MAV_4542|M.avium_104                GTGIRVQRLGSPDDDPVELLHELVSIYDAGRREPIPLPLKTSYAWAAARY
MAB_0400c|M.abscessus_ATCC_199      GPQPLVRSLGRPM-DPLGVLRGLVAIYDAGRREPLPLPLKTSYAWAQARR
MSMEG_1328|M.smegmatis_MC2_155      GTTPRVEGLGGPD-NPVDLLADLVAIYDAGRREPLPLPVKTSYAWAEARH
TH_1754|M.thermoresistible__bu      GTTPREELVGRPDGSPVELLRDLVAIYDAGRREPLPLPVKTSFAWAEARH
Mflv_5129|M.gilvum_PYR-GCK          G-RPTRERLLGPPDSAAEVLADLIAMYDAGRRAPIPLPLKTSYAWAETDF
Mvan_1210|M.vanbaalenii_PYR-1       GGNQTKERLLGPPEAAAEVLRDLVAMYDAGRCAPIPLPLKTSYAWAETEY
Mb0648c|M.bovis_AF2122/97           TRNHIARRLFVPPPDPVAVLRELVLLYDAGRREPLPLPLKTSCAWAQARR
Rv0631c|M.tuberculosis_H37Rv        TRNHIARRLFVPPPDPVAVLRELVLLYDAGRREPLPLPLKTSCAWAQARR
                                            :  *   .  :*  *: :*****  *:***:*** **. :  

MMAR_0958|M.marinum_M               CGDDPVREASFRWKSSDRYPAEDQAPAHVRTWGRN---ARLTDLMQPVRA
MUL_0709|M.ulcerans_Agy99           CGDDPVREASFRWKSSDRYPAEDQAPAHVRTWGRN---ARLTDLMQPVHA
MAV_4542|M.avium_104                GGDDPVAEARYRWKSSDRYPGEDQAPAHVRAWGRG---APLDDLMQPVRP
MAB_0400c|M.abscessus_ATCC_199      DRDDPELQAGYRWRSG-NFPGEDADPAVERAFGQG---VWLRHLMQPLRP
MSMEG_1328|M.smegmatis_MC2_155      CGDDPEQKAGFRWRSG-RYPGEDAEPAHVRAWGRD---AWLRDLMQPLRP
TH_1754|M.thermoresistible__bu      SGGDPERAALYRWRSN-NYPGEDQEPAHVRAWGRNGRPAWLQDLMQPLRP
Mflv_5129|M.gilvum_PYR-GCK          HRGQPLREAGWKWKTG-RYPGEDQDPAHIRVWGPH---LPLEDLVAAG--
Mvan_1210|M.vanbaalenii_PYR-1       HRGTPLREAGWKWKTG-RFPGEDAEPAHVRVWGPH---FPLSGLVSAG--
Mb0648c|M.bovis_AF2122/97           DGQDPYPPARECWQTNRFRPGDDDAPAHVRAWGPR---APFEVLLGKPRA
Rv0631c|M.tuberculosis_H37Rv        DGQDPYPPARECWQTNRFRPGDDDAPAHVRAWGPR---APFEVLLGKPRA
                                        *   *   *::.   *.:*  **  *.:*       :  *:     

MMAR_0958|M.marinum_M               ESERAACPNGEDNRLGAFAARLWLPMLRAERDPG
MUL_0709|M.ulcerans_Agy99           ESERAACPNGEDNRLGAFAARLWLPMLRAERDPG
MAV_4542|M.avium_104                GEE----CDGEDNRLGAYAARLWLPMLRAERTTA
MAB_0400c|M.abscessus_ATCC_199      GEE----TEGETNRLGAYSARLWLPLLRAERGA-
MSMEG_1328|M.smegmatis_MC2_155      GEE----FEGETHRLGAYSSRLWLPLLRAERPVR
TH_1754|M.thermoresistible__bu      GEE----SAGETHRLGAYSMRLWGPLLRAMDGPR
Mflv_5129|M.gilvum_PYR-GCK          --------------LPGFAARLWLPMLRAERSAR
Mvan_1210|M.vanbaalenii_PYR-1       --------------LPDYSTRLWQPMLLAERNPA
Mb0648c|M.bovis_AF2122/97           GEE----VAGEETRLGALAARLWLPLLAAEGSV-
Rv0631c|M.tuberculosis_H37Rv        GEE----VAGEETRLGALAARLWLPLLAAEGSV-
                                                  *   : *** *:* *