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M. bovis AF2122 / 97 Mb0370c (fba)

annotation: fructose-bisphosphate aldolase
coordinates: 442282 - 443316
length: 344

MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFGSGLGVKDMVT
GAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKGGNPLFQSHMWDGSAVPIDEN
LAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKLYTSPEDFEKTIEALGAGEHGKYLLAATFGN
VHGVYKPGNVKLRPDILAQGQQVAAAKLGLPADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQ
YAFTRPIAGHMFTNYDGVLKVDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0370cfba-100% (344)fructose-bisphosphate aldolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0234-1e-17385.42% (343) fructose-bisphosphate aldolase
M. tuberculosis H37RvRv0363cfba0.0100.00% (344) fructose-bisphosphate aldolase
M. leprae Br4923MLBr_00286fba1e-17687.72% (342) fructose-bisphosphate aldolase
M. abscessus ATCC 19977MAB_4254c-1e-16783.09% (343) fructose-bisphosphate aldolase
M. marinum MMMAR_0669fba0.090.06% (342) fructose-bisphosphate aldolase, Fba
M. avium 104-----
M. smegmatis MC2 155MSMEG_0752fbaA1e-17787.17% (343) fructose-bisphosphate aldolase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0103fba0.089.77% (342) fructose-bisphosphate aldolase
M. vanbaalenii PYR-1Mvan_0670-1e-17586.59% (343) fructose-bisphosphate aldolase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0370c|M.bovis_AF2122/97           -----MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAG
Rv0363c|M.tuberculosis_H37Rv        -----MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAG
MLBr_00286|M.leprae_Br4923          -----MPIATPEIYAEMLRRAKENSYAFPAINCTSSETVNAAIKGFADAG
MMAR_0669|M.marinum_M               -----MPIATPEVYAEMLGRAKENSYAFPAINCTSSETVNAALKGFADAG
MUL_0103|M.ulcerans_Agy99           -----MPIATPEVYAEMLGRAKENSYAFPAINCTSSETVNAALKGFADAG
Mflv_0234|M.gilvum_PYR-GCK          -----MPIATPEVYAEMLARAKEHSFAFPAINCVGSESVNAAIKGFADAG
Mvan_0670|M.vanbaalenii_PYR-1       -----MPIATPEVYAEMLGRAKEHSFAFPAINCVGSESVNAAIKGFADAG
MSMEG_0752|M.smegmatis_MC2_155      -----MPIATPEVYAEMLDRAKAHSFAFPAINCVGSESINAAIKGFADAG
MAB_4254c|M.abscessus_ATCC_199      MEVTQVPIATPEVYTEMLKRAKEHSFAFPAINCTSSETINAAIKGFADAG
                                         :******:*:*** :** :*:*******..**::***:*******

Mb0370c|M.bovis_AF2122/97           SDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTD
Rv0363c|M.tuberculosis_H37Rv        SDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTD
MLBr_00286|M.leprae_Br4923          SDGIIQFSTGGAEFASGLGVKDMVTGAVALAKFTHTIAAKYPINVALHTD
MMAR_0669|M.marinum_M               SDGIIQFSTGGAEFGSGLGIKNMVTGAVALAEFTHIVAAKYPINVALHTD
MUL_0103|M.ulcerans_Agy99           SDGIIQFSTGGAEFGSGLGIKNMVTGAVALAEFTHIVAAKYPINVALHTD
Mflv_0234|M.gilvum_PYR-GCK          SDGIIQFSTGGAEFASGLGVKDMVTGAVALAEFAHVIAEKYPITVALHTD
Mvan_0670|M.vanbaalenii_PYR-1       SDGIIQFSTGGAEFASGLGVKEMVTGAVALAEFAHVIAAKYDITVALHTD
MSMEG_0752|M.smegmatis_MC2_155      SDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFAHVVAAKYPITVALHTD
MAB_4254c|M.abscessus_ATCC_199      SDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFAHVVAAKYDITVALHTD
                                    **************.****:*:*********:*:* :* ** :.******

Mb0370c|M.bovis_AF2122/97           HCPKDKLDSYVRPLLAISAQRVSKGGNPLFQSHMWDGSAVPIDENLAIAQ
Rv0363c|M.tuberculosis_H37Rv        HCPKDKLDSYVRPLLAISAQRVSKGGNPLFQSHMWDGSAVPIDENLAIAQ
MLBr_00286|M.leprae_Br4923          HCPKDKLDSYVRPLLAISARRVATGKDPLFGSHMWDGSAIPIDENLAIAQ
MMAR_0669|M.marinum_M               HCPKDKLDTYVRPLLAISAERVSAGKDPLFQSHMWDGSAVPIDENLVIAQ
MUL_0103|M.ulcerans_Agy99           HCPKDKLDTYVRPLLAISAERVSAGKDPLFQSHMWDGSAVPIDENLVIAQ
Mflv_0234|M.gilvum_PYR-GCK          HCPKDKLDTYVRPLLAISSERVQAGRNPLFQSHMWDGSAVPIDENLSIAQ
Mvan_0670|M.vanbaalenii_PYR-1       HCPKDKLDTYVRPLLAISAERVARGQNPLFQSHMWDGSAVPIDENLSIAQ
MSMEG_0752|M.smegmatis_MC2_155      HCPKDKLDTYVRPLLAISAERVARGENPLFQSHMWDGSAVPIDENLTIAQ
MAB_4254c|M.abscessus_ATCC_199      HCPKDKLDTYVRPLLAISQERVNAGQAPLFQSHMWDGSAVPIDENLTIAA
                                    ********:********* .**  *  *** ********:****** ** 

Mb0370c|M.bovis_AF2122/97           ELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKLYTSPEDFEKTIEALG
Rv0363c|M.tuberculosis_H37Rv        ELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKLYTSPEDFEKTIEALG
MLBr_00286|M.leprae_Br4923          DLLKDAAAAKIILEVEIGVVGGEEDGVAGEINEKLYTTPKDFVKTIDALG
MMAR_0669|M.marinum_M               ELLKAAVAAKIILEIEIGVVGGEEDGVEAEINEKLYTTPEDFEKTVDALG
MUL_0103|M.ulcerans_Agy99           ELLKAAVAAKIILEIEIGVVGGEEDGVEAEINEKLYTTPEDFEKTVDALG
Mflv_0234|M.gilvum_PYR-GCK          ELLKQAAAAKIILEIEIGVVGGEEDGVEAEINDKLYTTPEDFEKTIEALG
Mvan_0670|M.vanbaalenii_PYR-1       ELLKQAAAAKIILEIEIGVVGGEEDGVEAEINDKLYTTPEDFEKTIEALG
MSMEG_0752|M.smegmatis_MC2_155      ELLKTAAAAKIILEVEIGVVGGEEDGVEAEINDKLYTSPEDFEKTIAALG
MAB_4254c|M.abscessus_ATCC_199      ELLSAAVKAKIILEVEIGVVGGEEDGVEAEINEKLYTSSEDFEKTVDALG
                                    :**. *. ******:************  ***:****:.:** **: ***

Mb0370c|M.bovis_AF2122/97           AGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGLPADAK
Rv0363c|M.tuberculosis_H37Rv        AGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGLPADAK
MLBr_00286|M.leprae_Br4923          AGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAEGQKVAAAKLSQSEGSK
MMAR_0669|M.marinum_M               AGEQGTYLLAATFGNVHGVYKPGNVKLRPDILDQGQKVAAAKLGLPDSAK
MUL_0103|M.ulcerans_Agy99           AGEQGTYLLAATFGNVHGAYKPGNVKLRPDILDQGQKVAAAKLGLPASAK
Mflv_0234|M.gilvum_PYR-GCK          VGEHGKYLLAATFGNVHGVYKPGNVKLKPEVLAEGQKVASAKLGLEDGSK
Mvan_0670|M.vanbaalenii_PYR-1       AGEHGKYLLAATFGNVHGVYKPGNVVLKPEVLAEGQRVASAKLGLPAGSK
MSMEG_0752|M.smegmatis_MC2_155      AGEEGRYLLAATFGNVHGVYKPGNVVLKPEVLAEGQRVAAAKLGLPADAK
MAB_4254c|M.abscessus_ATCC_199      AGDKGHYLLAATFGNVHGVYKPGNVKLKPEVLAEGQKVASAKLGLPEGSK
                                    .*:.* ************.****** *:*::* :**:**:***.   .:*

Mb0370c|M.bovis_AF2122/97           PFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNY
Rv0363c|M.tuberculosis_H37Rv        PFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNY
MLBr_00286|M.leprae_Br4923          PFDFVFHGGSGSEKSEIEEALRYGVVKMNVDTDTQYAFTRPVSGHMFTNY
MMAR_0669|M.marinum_M               PFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFSRPIVGHMFTNY
MUL_0103|M.ulcerans_Agy99           PFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFSRPIVGHIFTNY
Mflv_0234|M.gilvum_PYR-GCK          PFDFVFHGGSGSLKSEIEDSLRYGVVKMNVDTDTQYAFTRPVAAHMFSNY
Mvan_0670|M.vanbaalenii_PYR-1       PFDFVFHGGSGSLKSEIEDSLRYGVVKMNVDTDTQYAFTRPIVGHMFTNY
MSMEG_0752|M.smegmatis_MC2_155      PFDFVFHGGSGSLKSEIEDSLKYGVVKMNVDTDTQYAFTRPIAGHMFTNY
MAB_4254c|M.abscessus_ATCC_199      PFDFVFHGGSGSLKSEIEDSLRYGVVKMNVDTDTQYAFTRPIAAHMFSNY
                                    ************ *****::*:****************:**: .*:*:**

Mb0370c|M.bovis_AF2122/97           DGVLKVDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH-
Rv0363c|M.tuberculosis_H37Rv        DGVLKVDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH-
MLBr_00286|M.leprae_Br4923          DGVLKVDGDVGNKKVYDPRSYLKKAEASMTERVLEACNDLRCAGKSVAAS
MMAR_0669|M.marinum_M               DGVLKVDGEVGNKKVYDPRSYLKKAEAGMTERVIEACNDLHCAGKSLAG-
MUL_0103|M.ulcerans_Agy99           DGVLKVDGEVGNKKVYDPRSYLKKAEAGMTERVIEACNDLHCAGKSLAG-
Mflv_0234|M.gilvum_PYR-GCK          DGVLKVDGEVGNKKVYDPRSYFKKAEASMAERVVEACNDLHSAGRSVSAG
Mvan_0670|M.vanbaalenii_PYR-1       DGVLKVDGEVGNKKVYDPRSYFKKAEAGMSERVVEACKDLHSAGRSVSAG
MSMEG_0752|M.smegmatis_MC2_155      DGVLKIDGEVGNKKTYDPRSYLKKAEASMSERVVEACNDLHSAGRSVTAA
MAB_4254c|M.abscessus_ATCC_199      DGVLKIDGEVGNKKTYDPRSYLKKAEANMSVRVVEACNDLKSAGRSVSAG
                                    *****:**:** **.******:*****.*: **::**:**:.**:*::  

Mb0370c|M.bovis_AF2122/97           --
Rv0363c|M.tuberculosis_H37Rv        --
MLBr_00286|M.leprae_Br4923          --
MMAR_0669|M.marinum_M               --
MUL_0103|M.ulcerans_Agy99           --
Mflv_0234|M.gilvum_PYR-GCK          --
Mvan_0670|M.vanbaalenii_PYR-1       --
MSMEG_0752|M.smegmatis_MC2_155      --
MAB_4254c|M.abscessus_ATCC_199      LA