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M. bovis AF2122 / 97 Mb0219c (-)

annotation: methyltransferase (methylase)
coordinates: 254833 - 256146
length: 437

MSIKAYAKTQGIAVTSVNGLVAGHGSVQETWLAMQSAAALSGTPRLVGFSCIDTFPEVLWLAQRARQAWD
GVRIVIGNAMATLNYERILRQHDCFDYVVVGDGEVAFTKLALALANDAAVDDVPGLARRSEQGQILRTPS
SLVDLDELPRPARDELPTVLADGFAASVFSTRGCPYRCTFCGTGAMSAMLGKDSYRAKSVDAVVDEIDYL
VSDYDVNFLSITDDLFISKHPGSQQRAADFANAVLRRGISVNFMVDIRLDSVVDLDLFKHLHRAGLRRVF
IGVETGSYEQLRAYRKQILTRGQDAADTINALQQLGIDVIPGTIMFHPTVQPDELRETVRLLRATKYTVG
FKFMSRIVPYPGTPLYQAYSDAGYLTAKWPLGQWEFVDPEASRVYADVVAKVAPDVGISFDEAEAYFLSR
LDEWENVIAGRIAEATS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0219c--100% (437)methyltransferase (methylase)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv0213c-0.0100.00% (437) methyltransferase (methylase)
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_1693-0.076.33% (431) methyltransferase
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb0219c|M.bovis_AF2122/97         ----------------------------------------MSIKAYAKTQ
Rv0213c|M.tuberculosis_H37Rv      ----------------------------------------MSIKAYAKTQ
MMAR_1693|M.marinum_M             MTILLVNPPGARRNGRSYLSEQKLGDPWVYSTMPMEHLGMMSIKAYAKTQ
                                                                          **********

Mb0219c|M.bovis_AF2122/97         GIAVTSVNGLVAGHGSVQETWLAMQSAAALSGTPRLVGFSCIDTFPEVLW
Rv0213c|M.tuberculosis_H37Rv      GIAVTSVNGLVAGHGSVQETWLAMQSAAALSGTPRLVGFSCIDTFPEVLW
MMAR_1693|M.marinum_M             GIEIATVNGLVAGHSSVQETWSAIENAVRCSGKPRLVGFSCIDTLPEVLW
                                  ** :::********.****** *::.*.  **.***********:*****

Mb0219c|M.bovis_AF2122/97         LAQRARQAWDGVRIVIGNAMATLNYERILRQHDCFDYVVVGDGEVAFTKL
Rv0213c|M.tuberculosis_H37Rv      LAQRARQAWDGVRIVIGNAMATLNYERILRQHDCFDYVVVGDGEVAFTKL
MMAR_1693|M.marinum_M             LAQRVRETWDDVQIALGNAIATLNYERILRQHDCFDFVIVGDAEVGFTKL
                                  ****.*::**.*:*.:***:****************:*:***.**.****

Mb0219c|M.bovis_AF2122/97         ALALANDAAVDDVPGLARRSEQGQILRTPSSLVDLDELPRPARDELPTVL
Rv0213c|M.tuberculosis_H37Rv      ALALANDAAVDDVPGLARRSEQGQILRTPSSLVDLDELPRPARDELPTVL
MMAR_1693|M.marinum_M             ANAVANGAALDDVPGLARRDDRGQIICSPSRLIDLDELPRPARDELPSVL
                                  * *:**.**:*********.::***: :** *:**************:**

Mb0219c|M.bovis_AF2122/97         ADGFAASVFSTRGCPYRCTFCGTGAMSAMLGKDSYRAKSVDAVVDEIDYL
Rv0213c|M.tuberculosis_H37Rv      ADGFAASVFSTRGCPYRCTFCGTGAMSAMLGKDSYRAKSVDAVVDEIDYL
MMAR_1693|M.marinum_M             ADGFSAAVFSTRGCPYRCTFCGTGAMSAMLGRNSYRAKSVDAVVDEIAYL
                                  ****:*:************************::************** **

Mb0219c|M.bovis_AF2122/97         VSDYDVNFLSITDDLFISKHPGSQQRAADFANAVLRRGISVNFMVDIRLD
Rv0213c|M.tuberculosis_H37Rv      VSDYDVNFLSITDDLFISKHPGSQQRAADFANAVLRRGISVNFMVDIRLD
MMAR_1693|M.marinum_M             KSDFDIGFLCITDDLFISKHPSSQQRAAEFADAMINSGVDVKFMMDIRLD
                                   **:*:.**.***********.******:**:*::. *:.*:**:*****

Mb0219c|M.bovis_AF2122/97         SVVDLDLFKHLHRAGLRRVFIGVETGSYEQLRAYRKQILTRGQDAADTIN
Rv0213c|M.tuberculosis_H37Rv      SVVDLDLFKHLHRAGLRRVFIGVETGSYEQLRAYRKQILTRGQDAADTIN
MMAR_1693|M.marinum_M             SVVDLELFKHLHKAGLRRVFVGLETGSYDQLRAYRKQIINRGQDAADTIN
                                  *****:******:*******:*:*****:*********:.**********

Mb0219c|M.bovis_AF2122/97         ALQQLGIDVIPGTIMFHPTVQPDELRETVRLLRATKYTVGFKFMSRIVPY
Rv0213c|M.tuberculosis_H37Rv      ALQQLGIDVIPGTIMFHPTVQPDELRETVRLLRATKYTVGFKFMSRIVPY
MMAR_1693|M.marinum_M             ALQQVGVDVIPGTIMFHPTVQPDELRETARLLRATKFISTYKFMGKITPY
                                  ****:*:*********************.*******:   :***.:*.**

Mb0219c|M.bovis_AF2122/97         PGTPLYQAYSDAGYLTAKWPLGQWEFVDPEASRVYADVVAKVAPDVGISF
Rv0213c|M.tuberculosis_H37Rv      PGTPLYQAYSDAGYLTAKWPLGQWEFVDPEASRVYADVVAKVAPDVGISF
MMAR_1693|M.marinum_M             PGTPLYQEYSDLGYLREEWPLGEWDFVDPEAARVYADVCSLIAPRPDLPY
                                  ******* *** ***  :****:*:******:****** : :**  .:.:

Mb0219c|M.bovis_AF2122/97         DEAEAYFLSRLDEWENVIAGRIAEATS---------------------
Rv0213c|M.tuberculosis_H37Rv      DEAEAYFLSRLDEWENVIAGRIAEATS---------------------
MMAR_1693|M.marinum_M             DEAEKFFLARLDEWDDVIAARNEQTAADGTGTLEPPGGPQTPELLSLT
                                  **** :**:*****::***.*  ::::