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VSPTSAARVRRLIGNRPLSARSVLASALLGADQARLTVAELVAVASLFGISDGAARTCLWRMVSSGELTS GEGSYALAGHLLERRQRVDEASRIADTAVGSWDRTWELAVVSLDRRSAADRLELRKAAMALHLAELREGV WIRPDNLDPQRLPISRSVLDRQCIHFHGATTDISADKASSLFSLDEWAANALALIQAMDAELDRSSRDVS AQRSSYQFALSIAVVRHLQRDPLLPAELIGDDWPGHPLRSTYLRLDEAFKRRMSHAFR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4885 | - | - | 100% (268) | hypothetical protein MUL_4885 |
| M. ulcerans Agy99 | MUL_0755 | - | 9e-35 | 40.43% (235) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0693 | - | 7e-34 | 37.14% (245) | hypothetical protein Mb0693 |
| M. gilvum PYR-GCK | Mflv_5085 | - | 4e-34 | 36.60% (235) | PaaX domain-containing protein, C- domain |
| M. tuberculosis H37Rv | Rv0674 | - | 8e-34 | 37.14% (245) | hypothetical protein Rv0674 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3858c | - | 4e-38 | 40.42% (240) | hypothetical protein MAB_3858c |
| M. marinum M | MMAR_0229 | - | 1e-146 | 98.13% (268) | hypothetical protein MMAR_0229 |
| M. avium 104 | MAV_4498 | - | 1e-33 | 39.57% (235) | hypothetical protein MAV_4498 |
| M. smegmatis MC2 155 | MSMEG_1389 | - | 7e-31 | 37.13% (237) | hypothetical protein MSMEG_1389 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1271 | - | 3e-34 | 37.45% (235) | PaaX domain-containing protein, C- domain |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5085|M.gilvum_PYR-GCK ---------MRRPAN-RMTARSVVLSVLLGAHPAWATAAELIRLTSDFGI
Mvan_1271|M.vanbaalenii_PYR-1 -----------------MTARSVVLSVLLGAHPAWATAAELIRLTSDFGI
MSMEG_1389|M.smegmatis_MC2_155 ---------MTVPDVRRMTARSVVLSVMLGAHPAWASSAELIRLTSDFGI
Mb0693|M.bovis_AF2122/97 --------------MPAMTARSVVLSVLLGAHPAWATASELIQLTADFGI
Rv0674|M.tuberculosis_H37Rv --------------MPAMTARSVVLSVLLGAHPAWATASELIQLTADFGI
MAV_4498|M.avium_104 --------------MPDLTARSVVLSVLLGAHPAHARASELVRLTSDFGI
MAB_3858c|M.abscessus_ATCC_199 --------MDNPVDHHPMTARSVILSLLLGAHPAELSVREIRALTTLFGI
MUL_4885|M.ulcerans_Agy99 MSPTSAARVRRLIGNRPLSARSVLASALLGADQARLTVAELVAVASLFGI
MMAR_0229|M.marinum_M MSPKSAARVRRLIGNRPLSARSVLASALLGADQARLTVAELVAVASLFGI
::****: * :***. * *: ::: ***
Mflv_5085|M.gilvum_PYR-GCK RESTVRVALTRMVSAGDLVRSEDGYRLSGRLLARQRRQDDV---LEPRRG
Mvan_1271|M.vanbaalenii_PYR-1 RESTVRVALTRMVGAGDLVRSEDGYRLSDRLLARQRRQDDA---ITPRRH
MSMEG_1389|M.smegmatis_MC2_155 REQTLRVALTRMVSAGDLVRSADGYRLSDRLMVRQRRQDDA---IDPKVH
Mb0693|M.bovis_AF2122/97 KETTLRVALTRMVGAGDLVRSADGYRLSDRLLARQRRQDEA---MRPRTR
Rv0674|M.tuberculosis_H37Rv KETTLRVALTRMVGAGDLVRSADGYRLSDRLLARQRRQDEA---MRPRTR
MAV_4498|M.avium_104 KESTLRVALTRMVNAGDLIRSADGYRLSDRLLARQRRQDDA---IDPKVR
MAB_3858c|M.abscessus_ATCC_199 SDTTVRVALTRMVAAGDLVRTEAGYRLAERLQARQLRQDEA---CDPHRG
MUL_4885|M.ulcerans_Agy99 SDGAARTCLWRMVSSGELTSGEGSYALAGHLLERRQRVDEASRIADTAVG
MMAR_0229|M.marinum_M SDGAARTCLWRMVSSGELTGGEGSYALAGHLLERRQRVDEASRIADTAVG
: : *..* *** :*:* .* *: :* *: * *:. .
Mflv_5085|M.gilvum_PYR-GCK EWDGLWTTLVITSVGADARTRAHLRNTLQNHRFAELRDGVWMRPANVE--
Mvan_1271|M.vanbaalenii_PYR-1 AWDGSWTMLVITSVGTDARTRAQLRNTLQDNRFAELREGVWMRPANVD--
MSMEG_1389|M.smegmatis_MC2_155 DHDGEWLTVVVTSVGTDARTRAWMRNTLQQYRFGELREGVWLRPDNLD--
Mb0693|M.bovis_AF2122/97 AWHGNWHMLIVTSIGTDARTRAALRTCMHHKRFGELREGVWMRPDNLD--
Rv0674|M.tuberculosis_H37Rv AWHGNWHMLIVTSIGTDARTRAALRTCMHHKRFGELREGVWMRPDNLD--
MAV_4498|M.avium_104 PWRGQWVTLIVTSVGDDARTRAALRNAMHDKRFGELREGVWMRPDNID--
MAB_3858c|M.abscessus_ATCC_199 SWDGTWKQLVITSVGRDARDRNDLRTTLRQSRFGEFREGVWLRPENLE--
MUL_4885|M.ulcerans_Agy99 SWDRTWELAVVSLDRRSAADRLELRKAAMALHLAELREGVWIRPDNLDPQ
MMAR_0229|M.marinum_M SWDRTWELAVVSLDRRSAADRLELRKAAMALHLAELREGVWVRPDNLDPQ
* ::: .* * :*. ::.*:*:***:** *::
Mflv_5085|M.gilvum_PYR-GCK -VQLGANITEK--ARILQARDERPAELATHLWDLTGWAVDGRRLLKEMDD
Mvan_1271|M.vanbaalenii_PYR-1 -LELGPDITEK--VRILAARDDEPAELAARLWDLPGWAATGRELLTRIAD
MSMEG_1389|M.smegmatis_MC2_155 -QALPGEITDR--VRVLRTRDDNPRDLAARLWDLPGWARTGELLLEAMAD
Mb0693|M.bovis_AF2122/97 -LDLESDVAAR--VRMLTARDEAPADLAGQLWDLSGWTEAGHRLLGDMAA
Rv0674|M.tuberculosis_H37Rv -LDLESDVAAR--VRMLTARDEAPADLAGQLWDLSGWTEAGHRLLGDMAA
MAV_4498|M.avium_104 -TQLGPDVTDR--ARVITARDDDPADLAGRLWDLPGWARAGHRLLDEMAA
MAB_3858c|M.abscessus_ATCC_199 -VDLPPSVTDH--VWILHTRTDRPEVLAAQLWDLTGWSTYATALLRWWDQ
MUL_4885|M.ulcerans_Agy99 RLPISRSVLDRQCIHFHGATTDISADKASSLFSLDEWAANALALIQAMDA
MMAR_0229|M.marinum_M RLPISRSVLDRQCIHFHGAATDISADKASSLFSLDEWAADALALIQAMDA
: .: : . : : . * *:.* *: . *:
Mflv_5085|M.gilvum_PYR-GCK AHDVPTR----------FVAAATIVRHLLTDPVLPDELLPADWPGADLRA
Mvan_1271|M.vanbaalenii_PYR-1 ADDVPGR----------FVVAAAMVRHLLTDPVLPDELLATDWPGAALRS
MSMEG_1389|M.smegmatis_MC2_155 ATDVPAR----------FVVAAGIVRHLLVDPVLPDDLLPASWPGAALRA
Mb0693|M.bovis_AF2122/97 ATDMPGR----------FVVAAAMVRHLLTDPMLPAELLPADWPGAGLRA
Rv0674|M.tuberculosis_H37Rv ATDMPGR----------FVVAAAMVRHLLTDPMLPAELLPADWPGAGLRA
MAV_4498|M.avium_104 APDVPGR----------FVVAAAMVRHLLTDPVLPDELLPPDWPGTRLRA
MAB_3858c|M.abscessus_ATCC_199 AEAIPAR----------FVLAAAMVRHLLADPVLPDELLPADWPADEMRA
MUL_4885|M.ulcerans_Agy99 ELDRSSRDVSAQRSSYQFALSIAVVRHLQRDPLLPAELIGDDWPGHPLRS
MMAR_0229|M.marinum_M ELDRSSRDVSAQRSSYQFALSIAVVRHLQRDPLLPAELIGDDWPGHPLRS
. * *. : :**** **:** :*: .**. :*:
Mflv_5085|M.gilvum_PYR-GCK AYNDFAAEMVARRDDVKLTEAG-
Mvan_1271|M.vanbaalenii_PYR-1 AYNDFAAEMVARRDGVELMEAR-
MSMEG_1389|M.smegmatis_MC2_155 AYNDFAAELVARRDRTELMEAT-
Mb0693|M.bovis_AF2122/97 AYHDFATAMAKRRDATQLLEVT-
Rv0674|M.tuberculosis_H37Rv AYHDFATAMAKRRDATQLLEVT-
MAV_4498|M.avium_104 AYHDFAAELMARRDP-LFAEAT-
MAB_3858c|M.abscessus_ATCC_199 RYREFKDELVTLRDTAEMEEASL
MUL_4885|M.ulcerans_Agy99 TYLRLDEAFKRRMSHAFR-----
MMAR_0229|M.marinum_M TYLRLDEAFKRRMSHAFR-----
* : : .