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M. ulcerans Agy99 MUL_4300 (leuA)

annotation: 2-isopropylmalate synthase
coordinates: 4776991 - 4778691
length: 566

MPVNRYRPFAEEVEHIRVTDRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEI
EVGFPSASQTDFDFVREIITEGAIPDDVTIQVLTQCRPELIERTFEACAGASKVIVHFYNSTSILQRRVV
FRADRAAVEAIATDGARRCVEEAAKYPDTQWRFEYSPESYTGTELEYAKQVCDAVAEVIQPTPENPIIFN
LPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAGADRIEGCLFGNGERTG
NVCLATLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVPERHPYGGDLVYTAFSGSHQDAINKGLDAM
EFDADAADSDMDDMLWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLALPRRLQIEFSRA
IQEIAEGSAGEGGEVSPKEMWDAFAEEYLAPVRPLERIKQRVIAAEEDGGTTSIDATVKIDGKEAEISGS
GNGPLAAFVHALGTVGFDVAVLDYSEHAMSAGDDAQAAAYVEASVAGKTVWGVGIAPSITTASLRAVVSA
INRASR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4300leuA-100% (566)2-isopropylmalate synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3737leuA0.091.40% (535) 2-isopropylmalate synthase
M. gilvum PYR-GCKMflv_1293-0.085.16% (566) 2-isopropylmalate synthase
M. tuberculosis H37RvRv3710leuA0.085.43% (604) 2-isopropylmalate synthase
M. leprae Br4923MLBr_02324leuA0.088.65% (564) 2-isopropylmalate synthase
M. abscessus ATCC 19977MAB_0337c-0.082.52% (572) 2-isopropylmalate synthase
M. marinum MMMAR_5225leuA0.098.94% (566) 2-isopropylmalate synthase LeuA
M. avium 104MAV_0392leuA0.089.58% (566) 2-isopropylmalate synthase
M. smegmatis MC2 155MSMEG_6271leuA0.082.51% (566) 2-isopropylmalate synthase
M. thermoresistible (build 8)TH_2283leuA0.083.54% (565) 2-ISOPROPYLMALATE SYNTHASE LEUA (ALPHA-ISOPROPYLMALATE
M. vanbaalenii PYR-1Mvan_5515-0.082.60% (569) 2-isopropylmalate synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1293|M.gilvum_PYR-GCK          ----MTENYNPSADAFSSVRTIVTPAGKPNPGQPSWNTQRASSMPVNRYR
Mvan_5515|M.vanbaalenii_PYR-1       ----MTENYSPSADAYSSVRTITTPAGPPNPGQPSWNTQRGSSMPVSRYR
MSMEG_6271|M.smegmatis_MC2_155      -----MNTPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYR
TH_2283|M.thermoresistible__bu      -----VTNPIPSPDAYSSVRAITTPSGGRREGQPPWNPQQNSSMPVSRYR
MAB_0337c|M.abscessus_ATCC_199      ------MTSFSSDEFNYTPRSVVTPNGPIPADQPAWNTQKNSSMPVHRYR
MUL_4300|M.ulcerans_Agy99           -------------------------------------------MPVNRYR
MMAR_5225|M.marinum_M               ---MTNSSQAPGPDAFTSARTIVKPAGPPSPGQPVWNPQRASSMPVNRYR
Mb3737|M.bovis_AF2122/97            -------------------------------------------MPVNRYR
Rv3710|M.tuberculosis_H37Rv         -------------------------------------------MPVNRYR
MLBr_02324|M.leprae_Br4923          MASFSESLSQDPADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYR
MAV_0392|M.avium_104                --------MTSHPDAFSSSRSIVKPAGPPGPGQPAWNPQRGSSMPVNRYR
                                                                               *** ***

Mflv_1293|M.gilvum_PYR-GCK          SFDDEV---EPIRLPDRTWPEKAITTAPMWAAVDLRDGNQALIDPMSPQR
Mvan_5515|M.vanbaalenii_PYR-1       NFAAEVPGGAPAAPFDRTWPDKVIDTAPLWCAVDLRDGNQALIDPMSPAR
MSMEG_6271|M.smegmatis_MC2_155      SFADEV---EKISLPDRTWPDKVIETAPMWCAVDLRDGNQALIDPMSPQR
TH_2283|M.thermoresistible__bu      SFADEV---EHITLPDRTWPDKVIDRAPLWCAVDLRDGNQALIDPMSPAR
MAB_0337c|M.abscessus_ATCC_199      SFTDEV---EKIELPDRTWPDKVITRAPQWGAVDLRDGNQALIDPMSPAR
MUL_4300|M.ulcerans_Agy99           PFAEEV---EHIRVTDRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPAR
MMAR_5225|M.marinum_M               PFAEEV---EHIRVTDRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPAR
Mb3737|M.bovis_AF2122/97            PFAEEV---EPIRLRNRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPAR
Rv3710|M.tuberculosis_H37Rv         PFAEEV---EPIRLRNRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPAR
MLBr_02324|M.leprae_Br4923          PFAKEV---EPIRLVDRTWPDRVIDCAPLWCAVDLRDGNQALIDPMSPIC
MAV_0392|M.avium_104                PFAEEV---EPIRLPDRTWPDKVIDRAPLWCAVDLRDGNQALIDPMSPAR
                                     *  **         :****::.*  ** * *****************  

Mflv_1293|M.gilvum_PYR-GCK          KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIEQGAIPDDVTIQVLT
Mvan_5515|M.vanbaalenii_PYR-1       KRRMFDLLVKMGYKEIEVGFPSASQTDYDFVREIIEQGAIPDDVTIQVLT
MSMEG_6271|M.smegmatis_MC2_155      KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIEDNAIPDDVTIQVLT
TH_2283|M.thermoresistible__bu      KRRMFDLLVRMGYKEIEVGFPSASQTDYDFVREIITDNAIPDDVTIQVLT
MAB_0337c|M.abscessus_ATCC_199      KRRMFDLQIRMGFKEIEVGFPSASQTDFDFIRELITENAIPDDVTIQVLT
MUL_4300|M.ulcerans_Agy99           KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIITEGAIPDDVTIQVLT
MMAR_5225|M.marinum_M               KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIITEGAIPDDVTIQVLT
Mb3737|M.bovis_AF2122/97            KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIEQGAIPDDVTIQVLT
Rv3710|M.tuberculosis_H37Rv         KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIEQGAIPDDVTIQVLT
MLBr_02324|M.leprae_Br4923          KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIITDGTIPDDVTIQVLT
MAV_0392|M.avium_104                KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIVTEGAIPDDVTIQVLT
                                    ******* ::**:**************:**:**:: :.:***********

Mflv_1293|M.gilvum_PYR-GCK          QCRPELIERTFLACQGAPRAIVHFYNSTSILQRRVVFRADRDAVKQIATD
Mvan_5515|M.vanbaalenii_PYR-1       QCRDELIERTFEACDGAPNVIVHFYNSTSILQRRVVFRADRDEIKKIATD
MSMEG_6271|M.smegmatis_MC2_155      QSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRADKAAIKKIATD
TH_2283|M.thermoresistible__bu      QCRPELIEKTFEACQGAPRVIVHFYNSTSILQRRVVFRADREEVKQIAVE
MAB_0337c|M.abscessus_ATCC_199      QCRPELIERTFLACEGASKVIVHFYNSTSILQRRVVFREDKDAIKKIATD
MUL_4300|M.ulcerans_Agy99           QCRPELIERTFEACAGASKVIVHFYNSTSILQRRVVFRADRAAVEAIATD
MMAR_5225|M.marinum_M               QCRPELIERTFEACAGASKVIVHFYNSTSILQRRVVFRADRAAVQAIATE
Mb3737|M.bovis_AF2122/97            QCRPELIERTFQACSGAHRAIVHFYNSTSILQRRVVFRANRAEVQAIATD
Rv3710|M.tuberculosis_H37Rv         QCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRANRAEVQAIATD
MLBr_02324|M.leprae_Br4923          QCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVKAIATD
MAV_0392|M.avium_104                QCRPELIERTFAACQGAPQAIVHFYNSTSILQRRVVFRADRAAVQEIAVA
                                    *.* *** :** ** .* ..****************** ::  :: **. 

Mflv_1293|M.gilvum_PYR-GCK          GARMCVEEAKKYPGTQWRYEYSPESYTGTELEYAVEVCNAVAEVVQPTPE
Mvan_5515|M.vanbaalenii_PYR-1       GARKCLEEAGKHPGTRWRYEYSPESYTGTELEYALDVCNAVSEVIEPTPD
MSMEG_6271|M.smegmatis_MC2_155      AAELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD
TH_2283|M.thermoresistible__bu      GARMCLAEAEKYPGTLWRYEYSPESYTGTELQYAAEVCNAVAEVIEPTPE
MAB_0337c|M.abscessus_ATCC_199      GAHKCVEEAAKYPDTHWRFQYSPESYTGTELQYALEVCNAVGDIVEPTPD
MUL_4300|M.ulcerans_Agy99           GARRCVEEAAKYPDTQWRFEYSPESYTGTELEYAKQVCDAVAEVIQPTPE
MMAR_5225|M.marinum_M               GARRCVEEAAKYPDTQWRFEYSPESYTGTELEYAKQVCDAVAEVIQPTPE
Mb3737|M.bovis_AF2122/97            GARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE
Rv3710|M.tuberculosis_H37Rv         GARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE
MLBr_02324|M.leprae_Br4923          GARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPD
MAV_0392|M.avium_104                GARKCVEEAAKYPETRWRFEYSPESYTGTELEYAKQVCDAVGEIIRPTPE
                                    .*.  : :* *:* * **::***********.** :**:** ::: .**:

Mflv_1293|M.gilvum_PYR-GCK          WPLIVNLPATVEMATPNVYADSIEWMHRHLTPRDSIILSLHPHNDRGTAV
Mvan_5515|M.vanbaalenii_PYR-1       WPLIVNLPATVEMATPNVYADSIEWMSRNLARRGSIILSLHPHNDRGTAV
MSMEG_6271|M.smegmatis_MC2_155      NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGV
TH_2283|M.thermoresistible__bu      WPLIVNLPATVEMATPNVYADSIEWMSRRLTPRDSIILSLHPHNDRGTAV
MAB_0337c|M.abscessus_ATCC_199      NPIIFNLPSTVEMTTPNVYADSIEWMSRNLARRDSVILSLHPHNDRGTAV
MUL_4300|M.ulcerans_Agy99           NPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAV
MMAR_5225|M.marinum_M               NPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAV
Mb3737|M.bovis_AF2122/97            RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAV
Rv3710|M.tuberculosis_H37Rv         RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAV
MLBr_02324|M.leprae_Br4923          NPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAV
MAV_0392|M.avium_104                NPIIFNLPATVEMATPNVYADSIEWMSRNLARRDSVILSLHPHNDRGTAV
                                     *:*.***:****:************ *.*: * *:************.*

Mflv_1293|M.gilvum_PYR-GCK          AAAELGYAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSN
Mvan_5515|M.vanbaalenii_PYR-1       AAAELGYQAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSN
MSMEG_6271|M.smegmatis_MC2_155      AAAELGYQAGADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSN
TH_2283|M.thermoresistible__bu      AAAELGYQAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSN
MAB_0337c|M.abscessus_ATCC_199      AAAELGFQAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSN
MUL_4300|M.ulcerans_Agy99           AAAELGFAAGADRIEGCLFGNGERTGNVCLATLGLNLFSRGVDPQIDFSN
MMAR_5225|M.marinum_M               AAAELGFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSN
Mb3737|M.bovis_AF2122/97            AAAELGFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSN
Rv3710|M.tuberculosis_H37Rv         AAAELGFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSN
MLBr_02324|M.leprae_Br4923          AAAELGYHAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSN
MAV_0392|M.avium_104                AAAELGYAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSN
                                    ******: **********************.*****:*************

Mflv_1293|M.gilvum_PYR-GCK          IDEIRRTVEYCNQLAVPERHPYGGDLVYTAFSGSHQDAINKGLDAMKFDA
Mvan_5515|M.vanbaalenii_PYR-1       IDEIRRTVEYCNQLGVHERHPYGGDLVYTAFSGSHQDAINKGLDAMKISA
MSMEG_6271|M.smegmatis_MC2_155      IDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKVDA
TH_2283|M.thermoresistible__bu      IDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGFDQMKIDA
MAB_0337c|M.abscessus_ATCC_199      IDEIRHTVEYCNQLKVPERHPYGGDLVYTAFSGSHQDAINKGLDQMKRDA
MUL_4300|M.ulcerans_Agy99           IDEIRRTVEYCNQLPVPERHPYGGDLVYTAFSGSHQDAINKGLDAMEFDA
MMAR_5225|M.marinum_M               IDEIRRTVEYCNQLPVPERHPYGGDLVYTAFSGSHQDAINKGLDAMKFDA
Mb3737|M.bovis_AF2122/97            IDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDAMKLDA
Rv3710|M.tuberculosis_H37Rv         IDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDAMKLDA
MLBr_02324|M.leprae_Br4923          IDEIRRTVEYCNKLRVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKIDA
MAV_0392|M.avium_104                IDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDQMEIDA
                                    *****:******:* * *************************:* *: .*

Mflv_1293|M.gilvum_PYR-GCK          DAADKDVDDLLWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKAD
Mvan_5515|M.vanbaalenii_PYR-1       DEQDSDVDDIVWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKAD
MSMEG_6271|M.smegmatis_MC2_155      DAAGADMDDILWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKAD
TH_2283|M.thermoresistible__bu      DTAGVDVDDLLWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKTD
MAB_0337c|M.abscessus_ATCC_199      DEADSDVDDILWQVPYLPIDPKDVGRNYEAVIRVNSQSGKGGVAYIMKSD
MUL_4300|M.ulcerans_Agy99           DAADSDMDDMLWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKAD
MMAR_5225|M.marinum_M               DAADSDMDDMLWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKAD
Mb3737|M.bovis_AF2122/97            DAADCDVDDMLWQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVAYIMKTD
Rv3710|M.tuberculosis_H37Rv         DAADCDVDDMLWQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVAYIMKTD
MLBr_02324|M.leprae_Br4923          DAADSDVDDILWQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVAYIMKAD
MAV_0392|M.avium_104                DAADTDVEDMLWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKAD
                                    *  . *::*::**********:****.*********************:*

Mflv_1293|M.gilvum_PYR-GCK          HGLALPRRLQIEFSQVIQQITD---GEGGEVSPKEMWDAFYEEYLAPVTP
Mvan_5515|M.vanbaalenii_PYR-1       HGLALPRRLQIEFSQAIQQITD---GEGGEVSPKEMWDAFYDEYLAPITP
MSMEG_6271|M.smegmatis_MC2_155      HGLVLPRRLQIEFSQVIQQITD---GEGGEVSPKEMWDAFSEEYLAPITP
TH_2283|M.thermoresistible__bu      HGLVLPRRLQIEFSQVVQAITD---GEGGEVSAKEMWDVFAEEYLNPIRP
MAB_0337c|M.abscessus_ATCC_199      HGLVLPRRLQIEFAQSIQRITD---GEGGEVNPKEIWDVFAEEYLAPITP
MUL_4300|M.ulcerans_Agy99           HGLALPRRLQIEFSRAIQEIAEGSAGEGGEVSPKEMWDAFAEEYLAPVRP
MMAR_5225|M.marinum_M               HGLALPRRLQIEFSRAIQEIAEGSAGEGGEVSPKEMWDAFAEEYLAPVRP
Mb3737|M.bovis_AF2122/97            HGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAFAEEYLAPVRP
Rv3710|M.tuberculosis_H37Rv         HGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAFAEEYLAPVRP
MLBr_02324|M.leprae_Br4923          HGLELPRRLQIEFSRAIQKISE---GEGGEITPTEMWDVFFEEYLSPVQP
MAV_0392|M.avium_104                HGLALPRRLQIEFSQVIQKISE---GEGGEVSPKEMWDAFFEEYLAPVWP
                                    *** *********:: :* *::   *****:...*:**.* :*** *: *

Mflv_1293|M.gilvum_PYR-GCK          LERIRQKVDAAEVDGGTDTITAVVKIDGEEREIVGAGNGPLAAFVDAVGA
Mvan_5515|M.vanbaalenii_PYR-1       LERIRQKVDASEVDGGTDTITAVVKVNGEEHEIVGAGNGPLAAFVDAIGA
MSMEG_6271|M.smegmatis_MC2_155      LERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA
TH_2283|M.thermoresistible__bu      LERIRQKVIASEVDDGVDRIEAVVKVDGVEKEIAGKGNGPLAAFVDALGT
MAB_0337c|M.abscessus_ATCC_199      LERIRQKVTASEEDGGTDSIAAVVKIDGKETEVNGTGNGPLAAFVDALST
MUL_4300|M.ulcerans_Agy99           LERIKQRVIAAEEDGGTTSIDATVKIDGKEAEISGSGNGPLAAFVHALGT
MMAR_5225|M.marinum_M               LERIKQRVIAAEEDGGTTSIDATVKIDGKETEISGSGNGPLAAFVHALGS
Mb3737|M.bovis_AF2122/97            LERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD
Rv3710|M.tuberculosis_H37Rv         LERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD
MLBr_02324|M.leprae_Br4923          LERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGH
MAV_0392|M.avium_104                LERVKQRVDASDEDSGVTSISATVKINGEQTEINGTGNGPLAAFVHALAG
                                    ***::*:* *:: *.*   * *.**::* : *: * ******** .*:. 

Mflv_1293|M.gilvum_PYR-GCK          VGFNVNVLDYSEHAMSAGEEAQAAAYVEAEIDG-----------------
Mvan_5515|M.vanbaalenii_PYR-1       VGFHVNVLDYSEHAMSAGEEAAAAAYVEAEIDG-----------------
MSMEG_6271|M.smegmatis_MC2_155      LGINVNVRDYSEHAMSAGEEAQAAAYVEAEIDG-----------------
TH_2283|M.thermoresistible__bu      VGFDVSVLDYSEHAMSAGEEAQAAAYVEAAVNG-----------------
MAB_0337c|M.abscessus_ATCC_199      VGYTVNVLDYSEHALSAGDDAQAAAYVEATVVSPGGGE------------
MUL_4300|M.ulcerans_Agy99           VGFDVAVLDYSEHAMSAGDDAQAAAYVEASV-------------------
MMAR_5225|M.marinum_M               VGFDVAVLDYSEHAMSAGDDAQAAAYVEASV-------------------
Mb3737|M.bovis_AF2122/97            VGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPV
Rv3710|M.tuberculosis_H37Rv         VGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPV
MLBr_02324|M.leprae_Br4923          VGLQVAVLDYSEHAMNAGDDAQAAAYVEASVHG-----------------
MAV_0392|M.avium_104                VGFDVAVLDYSEHAMSSGDDAQAAAYVEASVNG-----------------
                                    :*  * * ** ***:.:*::* ******* :                   

Mflv_1293|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5515|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_6271|M.smegmatis_MC2_155      --------------------------------------------------
TH_2283|M.thermoresistible__bu      --------------------------------------------------
MAB_0337c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_4300|M.ulcerans_Agy99           ----------AG--------------------------------------
MMAR_5225|M.marinum_M               ----------AG--------------------------------------
Mb3737|M.bovis_AF2122/97            TIASPAQPGEAGRHASDPVTIASPAQPGEAGRHASDPVTIASPAQPGEAG
Rv3710|M.tuberculosis_H37Rv         TIASPAQPGEAG--------------------------------------
MLBr_02324|M.leprae_Br4923          --------------------------------------------------
MAV_0392|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_1293|M.gilvum_PYR-GCK          ----------------------------RTVWGVGIATSITTASLRAVVS
Mvan_5515|M.vanbaalenii_PYR-1       ----------------------------KTVWGVGIATSITTASLRAVVS
MSMEG_6271|M.smegmatis_MC2_155      ----------------------------KTVWGVGIATSITTASLRAVVS
TH_2283|M.thermoresistible__bu      ----------------------------TTVWGVGIATSITTASLRAVVS
MAB_0337c|M.abscessus_ATCC_199      ---------------------------AQTVWGVGIAPSITTASLRAVVS
MUL_4300|M.ulcerans_Agy99           ----------------------------KTVWGVGIAPSITTASLRAVVS
MMAR_5225|M.marinum_M               ----------------------------KTVWGVGIAPSITTASLRAVVS
Mb3737|M.bovis_AF2122/97            RHASDPVTIASPAQPGEAGRHASDPVTSKTVWGVGIAPSITTASLRAVVS
Rv3710|M.tuberculosis_H37Rv         -------------------RHASDPVTSKTVWGVGIAPSITTASLRAVVS
MLBr_02324|M.leprae_Br4923          ----------------------------HTAWGVGIAPSITTASLRAVVS
MAV_0392|M.avium_104                ----------------------------RTVWGVGIAPSITTASLRAVVS
                                                                 *.******.************

Mflv_1293|M.gilvum_PYR-GCK          AVNRAARLTAA---
Mvan_5515|M.vanbaalenii_PYR-1       AVNRAMRTRPSLLR
MSMEG_6271|M.smegmatis_MC2_155      AVNRAARA------
TH_2283|M.thermoresistible__bu      AVNRAAARS-----
MAB_0337c|M.abscessus_ATCC_199      AVNRAARA------
MUL_4300|M.ulcerans_Agy99           AINRASR-------
MMAR_5225|M.marinum_M               AINRASR-------
Mb3737|M.bovis_AF2122/97            AVNRAAR-------
Rv3710|M.tuberculosis_H37Rv         AVNRAAR-------
MLBr_02324|M.leprae_Br4923          AVNRAMPR------
MAV_0392|M.avium_104                AVNRAARA------
                                    *:***