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GEGPVFELVDVVVQRDRVRALDGFTAAVPAQGVTAVFGPSGSGKSTMLRLCNRLEVPTSGRVFFWGNDIA ECDPLWLRRRVGMCFQRPTPFAGTVADNLRVARPDASEAQMAETLARVALRGSWLDRDATALSGGEPQRM CLARTLLAQPQVLLLDAPNSAVDADGAAVIEGVVRELADDGIPALWVTHDAAQAERAADRILHITRGRCT GLDSVVDRPADGQVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4048 | pstB | - | 100% (226) | phosphate-transport ATP-binding protein ABC transporter PstB |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 1e-26 | 38.60% (215) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. ulcerans Agy99 | MUL_0440 | phoT | 2e-24 | 34.91% (212) | phosphate-transport ATP-binding protein ABC transporter, |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 9e-27 | 38.14% (215) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_0857 | - | 4e-26 | 36.54% (208) | ABC transporter related |
| M. tuberculosis H37Rv | Rv0933 | pstB | 8e-28 | 40.20% (204) | phosphate ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_02189 | phoT | 3e-23 | 35.38% (212) | phosphate transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_0749 | - | 3e-27 | 38.50% (213) | phosphate ABC transporter ATP-binding protein |
| M. marinum M | MMAR_4974 | pstB | 1e-125 | 97.35% (226) | phosphate-transport ATP-binding protein ABC transporter PstB |
| M. avium 104 | MAV_0668 | pstB | 1e-92 | 75.34% (223) | ABC transporter, ATP-binding protein PstB |
| M. smegmatis MC2 155 | MSMEG_4530 | cysA | 5e-27 | 38.60% (215) | sulfate ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_2424 | - | 4e-27 | 38.21% (212) | PUTATIVE sulfate ABC transporter, ATPase subunit |
| M. vanbaalenii PYR-1 | Mvan_3872 | - | 3e-26 | 37.67% (215) | sulfate ABC transporter, ATPase subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4530|M.smegmatis_MC2_155 --------MSDTSTQTNTSAIVVRGANKH--YGDFAALDNIDFEVPSGSL
TH_2424|M.thermoresistible__bu ----------------MTDAITVRGANKR--YGDFAALDNVDFAVPAGSL
Mvan_3872|M.vanbaalenii_PYR-1 ----------------MTHAITVEGANKR--YGDFAALDNVDFVVPAGSL
Mb2419c|M.bovis_AF2122/97 ----------------MTYAIVVADATKR--YGDFVALDHVDFVVPTGSL
Mflv_0857|M.gilvum_PYR-GCK ----------------MTSAVSLAATDIHLSFGTTAVLRGVDLDVAAGSS
MUL_4048|M.ulcerans_Agy99 -------MGE---------GPVFELVDVVVQRDRVRALDGFTAAVPAQGV
MMAR_4974|M.marinum_M -------MGE---------GPVFEFVDVVVQRDRVRALDGFTAAVPAQGV
MAV_0668|M.avium_104 MLQDERVTAE---------EPVFEFVDVVVERRGLRALDGLTAAIPGRGV
MLBr_02189|M.leprae_Br4923 --MAKRLD--------------LKGVNIYYG-SFQAVLD-VSLAVLPRSV
MAB_0749|M.abscessus_ATCC_1997 --MAKRLD--------------LKDVNIFYG-KFHAVQD-VALSVPPRNV
Rv0933|M.tuberculosis_H37Rv -MACERLGGQSGAADVDAAAPAMAAVNLTLGFAGKTVLDQVSMGFPARAV
. . . . .
MSMEG_4530|M.smegmatis_MC2_155 TALLGPSGSGKSTLLRAIAGLDQPDS-----GTVTINGRDVTG--VPP--
TH_2424|M.thermoresistible__bu TALLGPSGSGKSTLLRAIAGLDRPDT-----GTITINGRDVTD--VPP--
Mvan_3872|M.vanbaalenii_PYR-1 TALLGPSGSGKSTLLRAIAGLDEPDT-----GTITINGRDVTR--IPP--
Mb2419c|M.bovis_AF2122/97 TALLGPSGSGKSTLLRTIAGLDQPDT-----GTITINGRDVTR--VPP--
Mflv_0857|M.gilvum_PYR-GCK TAVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLR--DDPNA
MUL_4048|M.ulcerans_Agy99 TAVFGPSGSGKSTMLRLCNRLEVPTS-----GRVFFWGNDIAE--CDPLW
MMAR_4974|M.marinum_M TAVFGPSGSGKSTMLRLCNRLEVPTS-----GRVFFWGNDIAE--CDPLW
MAV_0668|M.avium_104 TAVFGPSGSGKSTLLRLCNRLELPTS-----GRVSFYGSDIAG--LDPLW
MLBr_02189|M.leprae_Br4923 TAFIGASGCGKTTVLRTLNRMHEVVPGARVEGTVLLDDEDIYAPGIDPVG
MAB_0749|M.abscessus_ATCC_1997 TAFIGPSGCGKSTVLRTLNRMHEVTPGARVEGSVLLDGADIYGSAVDPVS
Rv0933|M.tuberculosis_H37Rv TSLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGGRSIFN-YRDVLE
*:.:*.:*.**:*.** : * : : . .:
MSMEG_4530|M.smegmatis_MC2_155 QQRGIGFVFQHYAAFKHLSVRDNVAFG-LKIRKRPKAEIAERVDNLLEVV
TH_2424|M.thermoresistible__bu QRRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRRRPKREIAEKVDNLLEVV
Mvan_3872|M.vanbaalenii_PYR-1 QKRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRKKPKAEIKAKVDDLLEVV
Mb2419c|M.bovis_AF2122/97 QRRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKVDNLLQVV
Mflv_0857|M.gilvum_PYR-GCK LRQRIGMVFQQFQLFPHKSVLDNVTLGPRKLKKMSADAARELGMAQLDRV
MUL_4048|M.ulcerans_Agy99 LRRRVGMCFQRPTPFAGTVADNLRVARPDASEAQMAETLARVALR-----
MMAR_4974|M.marinum_M LRRRVGMCFQRPTPFAGTVADNLRVARPDASEAQMAETLARVALR-----
MAV_0668|M.avium_104 LRRRVGMCFQRPTPFPGTVADNLRVADPDADEARMRETLDRVALT-----
MLBr_02189|M.leprae_Br4923 VRRAIGMVFQRPNPFPAMSIRDNVVAGLKLQGVRNRKVLDDTAEYFLRGT
MAB_0749|M.abscessus_ATCC_1997 VRKTIGMVFQRPNPFPTMSIRDNVVAGLRLQGVRNKKTLDEVAERSLQGA
Rv0933|M.tuberculosis_H37Rv FRRRVGMLFQRPNPFP-MSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEV
:: :*: **: * :
MSMEG_4530|M.smegmatis_MC2_155 G----LSGFQTRYPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALDAK
TH_2424|M.thermoresistible__bu G----LAGFQNRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK
Mvan_3872|M.vanbaalenii_PYR-1 G----LAGFQSRYPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALDAK
Mb2419c|M.bovis_AF2122/97 G----LSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK
Mflv_0857|M.gilvum_PYR-GCK G----LRNKADVRPSTLSGGQQQRVAIARALAMSPQVMFFDEATSALDPE
MUL_4048|M.ulcerans_Agy99 ------GSWLDRDATALSGGEPQRMCLARTLLAQPQVLLLDAPNSAVDAD
MMAR_4974|M.marinum_M ------GSWLDRDATALSGGEAQRMCLARTLLAQPQVLLLDEPTSAVDAD
MAV_0668|M.avium_104 ------GAWLDRDVLALSGGEAQRVCLARTLMARPQVLLLDEPTSAVDAE
MLBr_02189|M.leprae_Br4923 NLWDEVKDRLDKPGGGLSGGQQQRLCIARAIAVQPDVLLMDEPCSSLDPI
MAB_0749|M.abscessus_ATCC_1997 NLWNEVKDRLDRPGGGLSGGQQQRLCIARAIAVQPDVLLMDEPCSALDPI
Rv0933|M.tuberculosis_H37Rv GLWDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPT
****: * :.:**:: *:*:::* . .::*.
MSMEG_4530|M.smegmatis_MC2_155 VRDDLRTWLRRLHDEVHVTTVLVTHDQSEALDVADRIAVLN------KGR
TH_2424|M.thermoresistible__bu VREDLRTWLRRLHEEVHVTTVLVTHDQSEALDVADRIAVLN------NGR
Mvan_3872|M.vanbaalenii_PYR-1 VREDLRAWLRRLHDEVHVTTVLVTHDQQEALDVADRIAVLN------KGR
Mb2419c|M.bovis_AF2122/97 VREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLH------KGR
Mflv_0857|M.gilvum_PYR-GCK LVKGVLALIAELASDG-MTMVVVTHEMGFARSTADQLVFMD------HGQ
MUL_4048|M.ulcerans_Agy99 GAAVIEGVVRELADDG-IPALWVTHDAAQAERAADRILHIT------RGR
MMAR_4974|M.marinum_M AAAVIEGAVRELADDG-IPALWVTHDAAQAERAADRILHIT------RGR
MAV_0668|M.avium_104 AAEVIERAVRELAADG-TPALWVTHDAAQVTRAADRVLRLE------RGR
MLBr_02189|M.leprae_Br4923 STMAIEELIGELKQE--YTIVIVTHNMQQAARVSDQTAFFNLEAVGRPGR
MAB_0749|M.abscessus_ATCC_1997 STLAIEDLISELKQE--FTIVIVTHNMQQAARVSDQTAFFNLEAAGKPGM
Rv0933|M.tuberculosis_H37Rv TTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALF------FDGR
: : * . : ***: . :*: : *
MSMEG_4530|M.smegmatis_MC2_155 IEQIGSPTEVYDQPANAFVMSFLGAVSEINGILVRPHDIRVGRTPEMAIA
TH_2424|M.thermoresistible__bu IEQVGSPAEVYDSPANEFVMSFLGAVSSLNGTLVRPHDIWVGRHPELP--
Mvan_3872|M.vanbaalenii_PYR-1 IEQVGSPTEVYDAPANAFVMSFLGAVSSLNGVLVRPHDIRVGRSPEMAIG
Mb2419c|M.bovis_AF2122/97 IEQVGSPTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVA
Mflv_0857|M.gilvum_PYR-GCK VVETGPPEQLFEAAETDRLRRFLSQVL-----------------------
MUL_4048|M.ulcerans_Agy99 CTG---LDSVVDRPADGQVS------------------------------
MMAR_4974|M.marinum_M CTG---LDSVVDRPADGQVS------------------------------
MAV_0668|M.avium_104 SLG---LSQVGGGPDDGAVPR-----------------------------
MLBr_02189|M.leprae_Br4923 LVEIDDTEKIFSNPTEKATEDYISGRFG----------------------
MAB_0749|M.abscessus_ATCC_1997 LVEIDDTEKIFSNPTQKATEDYISGRFG----------------------
Rv0933|M.tuberculosis_H37Rv LVEEGPTEQLFSSPKHAETARYVAGLSGDVKDAKRGN-------------
.: .
MSMEG_4530|M.smegmatis_MC2_155 ASDGTAEATGVLRATIDRIVMLGFEVRVELTSAASHVPFTAQITRGDAEA
TH_2424|M.thermoresistible__bu TSDSTLQATGVVRARIDRVVMLGFEVRLELTSATNNAPFTAQITRGDAEA
Mvan_3872|M.vanbaalenii_PYR-1 ASDDSVQATGVTRATIDRIVVLGFEVRVELTSAATHTPFTAQITRGDAEA
Mb2419c|M.bovis_AF2122/97 AADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEA
Mflv_0857|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4048|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4974|M.marinum_M --------------------------------------------------
MAV_0668|M.avium_104 --------------------------------------------------
MLBr_02189|M.leprae_Br4923 --------------------------------------------------
MAB_0749|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0933|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_4530|M.smegmatis_MC2_155 LGLEEGDTVYVRATRVPHIAGEAQVPRTATNNVNADAALAQ-----
TH_2424|M.thermoresistible__bu LGLRSGDTVYVRATRVPALP---------TGDVDERVAAR------
Mvan_3872|M.vanbaalenii_PYR-1 LGLKEGDTVYVRATRVPSLP----------DGVPLPVA--------
Mb2419c|M.bovis_AF2122/97 LALREGDTVYVRATRVPPIAG-------GVSGVDDAGVERVKVTST
Mflv_0857|M.gilvum_PYR-GCK ----------------------------------------------
MUL_4048|M.ulcerans_Agy99 ----------------------------------------------
MMAR_4974|M.marinum_M ----------------------------------------------
MAV_0668|M.avium_104 ----------------------------------------------
MLBr_02189|M.leprae_Br4923 ----------------------------------------------
MAB_0749|M.abscessus_ATCC_1997 ----------------------------------------------
Rv0933|M.tuberculosis_H37Rv ----------------------------------------------