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M. ulcerans Agy99 MUL_4015 (lprA)

annotation: lipoprotein LprA
coordinates: 4486257 - 4486997
length: 246

MKHPPRSVVATAVTLAVVLAIGGCSSNGGSGGPGTATGTTVTTSSAEAATILKQAAEAMRKVTGMHVNLT
VDGDVPNLRVTKLEGDIANSPQTVATGSATMLVGNKQEDAKFVYVDGHLYSDLGQPGTYTDFGDGASIYN
VSVLLDPNQGLANLLANLKEASVTGSEQVNGVATTKITGNSAADDIATLAGSRLTSADVTTVPTTVWIAT
DGSSHLVQIKILPTPATSVTLTMSDWGKQVTATKPV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4015lprA-100% (246)lipoprotein LprA
M. ulcerans Agy99MUL_1807lprG4e-3637.55% (237) lipoprotein LprG
M. ulcerans Agy99MUL_1773lprF1e-1928.78% (271) lipoprotein LprF

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1301clprA1e-10880.57% (247) putative lipoprotein LPRA
M. gilvum PYR-GCKMflv_3724-2e-3934.85% (241) hypothetical protein Mflv_3724
M. tuberculosis H37RvRv1270clprA1e-10980.97% (247) lipoprotein LprA
M. leprae Br4923MLBr_00557lprG1e-3636.18% (246) putative lipoprotein
M. abscessus ATCC 19977MAB_2806-8e-3436.68% (199) lipoprotein LprG precursor (27 kDa lipoprotein)
M. marinum MMMAR_4152lprA1e-13699.19% (246) lipoprotein LprA
M. avium 104MAV_3367-1e-4038.33% (240) LprG protein
M. smegmatis MC2 155MSMEG_3070-3e-4038.75% (240) LprG protein
M. thermoresistible (build 8)TH_1009lprG4e-4237.70% (244) PROBABLE CONSERVED LIPOPROTEIN LPRG
M. vanbaalenii PYR-1Mvan_2692-3e-4136.51% (241) hypothetical protein Mvan_2692

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3724|M.gilvum_PYR-GCK          MPPGRPAARSTRPDTRTLYDAGMQTR------------LLAIFAALFAAV
Mvan_2692|M.vanbaalenii_PYR-1       ----------------------MQTR------------LLAIFAALFAVV
MSMEG_3070|M.smegmatis_MC2_155      ----------------------MQTRP--------RFAVQSLFAILATAA
MLBr_00557|M.leprae_Br4923          ----------------------MQAPK-------HHRRLFAVLATLNTAT
MAV_3367|M.avium_104                ----------------------MQT----------RRRLSAVFASLTLAT
TH_1009|M.thermoresistible__bu      ----------------------MQTRFRHAGRTVPVRNLFALFALVALIV
MAB_2806|M.abscessus_ATCC_1997      ----------------------MRNR------------IRLALIPVAVAA
MUL_4015|M.ulcerans_Agy99           ----------------------MKHPP---------RSVVATA-VTLAVV
MMAR_4152|M.marinum_M               ----------------------MKHPP---------RSVVATA-VTLAVV
Mb1301c|M.bovis_AF2122/97           ----------------------MKHPP---------CSVVAAATAILAVV
Rv1270c|M.tuberculosis_H37Rv        ----------------------MKHPP---------CSVVAAATAILAVV
                                                          *:              :          .

Mflv_3724|M.gilvum_PYR-GCK          ALLAGCSS---------SSTEDSGKDLPDPTTLLSESSETTRNQTSAHLT
Mvan_2692|M.vanbaalenii_PYR-1       ALVAGCSG---------SSSKDSGKELPDAATLLQRSSETTKAQTSAHLN
MSMEG_3070|M.smegmatis_MC2_155      ALVAGCS----------SSSETSDAPLPDGAALLQESASKTKTQQSVHLL
MLBr_00557|M.leprae_Br4923          AVIAGCS----------SGSNLSSGPLPDATTWVKQATDITKNVTSAHLV
MAV_3367|M.avium_104                ALIAGCS----------SGSKQSGAPLPDPTSLVKQSADATKNVKSVHLV
TH_1009|M.thermoresistible__bu      G-VAGCSSG-------EDQADQSEQPTPDAATLLEEAAQTTRDLQSVRLD
MAB_2806|M.abscessus_ATCC_1997      IALAGCS-----------KTDKADPNLPEAATLLSESAATTKTQTSTHIV
MUL_4015|M.ulcerans_Agy99           LAIGGCSSNGGSGGPGTATGTTVTTSSAEAATILKQAAEAMRKVTGMHVN
MMAR_4152|M.marinum_M               LAIGGCSSNGGSGGPGTATGTTVTTSSAEAATILKQAAEAMRKVTGMHVN
Mb1301c|M.bovis_AF2122/97           LAIGGCSTEGDAG---KASDTAATASNGDAAMLLKQATDAMRKVTGMHVR
Rv1270c|M.tuberculosis_H37Rv        LAIGGCSTEGDAG---KASDTAATASNGDAAMLLKQATDAMRKVTGMHVR
                                      :.***                     : :  :..::   :   . :: 

Mflv_3724|M.gilvum_PYR-GCK          LSVQGQIAELPVEQLEGDLTQTPAVAAKGTANIIFLGQRLNDVEFVVSDG
Mvan_2692|M.vanbaalenii_PYR-1       LSVQGQIPDLPVESLEGDLTQSPAVAAKGTANIIFLGQRLNDVAFVVSDG
MSMEG_3070|M.smegmatis_MC2_155      LTVQGKVDGLPVEKLDGDLTNAPAVAAEGTADLIAFGQKIADAKFVIADG
MLBr_00557|M.leprae_Br4923          LSVNGKITGLPVKTLTGDLTTHPNTVASGNATITLDGADLN-ANFVVVDG
MAV_3367|M.avium_104                LSIQGKISGLPIKTLTGDLTTTPATAAKGNATITLGGSDID-ANFVVVDG
TH_1009|M.thermoresistible__bu      LTVQGEIPELPIETLQGDLTNVPEVGATGTADIIMMGQRFEDVDFVVAEG
MAB_2806|M.abscessus_ATCC_1997      LKVTGDKPTLKLSDLTGDLTTKPAVAAKGTAKT--GGLELP---FVVVDG
MUL_4015|M.ulcerans_Agy99           LTVDGDVPNLRVTKLEGDIANSPQTVATGSATMLVGNKQED-AKFVYVDG
MMAR_4152|M.marinum_M               LTVDGDVPNLRVTKLEGDISNSPQTVATGSATMLVGNKQED-AKFVYVDG
Mb1301c|M.bovis_AF2122/97           LAVTGDVPNLRVTKLEGDISNTPQTVATGSATLLVGNKSED-AKFVYVDG
Rv1270c|M.tuberculosis_H37Rv        LAVTGDVPNLRVTKLEGDISNTPQTVATGSATLLVGNKSED-AKFVYVDG
                                    * : *.   * :  * **::  * . * *.*     .       **  :*

Mflv_3724|M.gilvum_PYR-GCK          DLWATITAGGSLSNFGPAADVYDVAAILDPNVGLANVLANFSN-PSADGR
Mvan_2692|M.vanbaalenii_PYR-1       DLYAAITAGGALSNFGPASDVYDVAAILNPDVGLANVLANFSN-PTADGR
MSMEG_3070|M.smegmatis_MC2_155      NLYAALTPGDPLSNYGAAANIYDVSAILNPDTGLANVLANFSD-ATADGR
MLBr_00557|M.leprae_Br4923          ELYATLTPS-KWSDFGKASDIYDVASILNPDAGLANVLANFTG-AKTEGR
MAV_3367|M.avium_104                TLYATLTPN-KWSDFGKASDIYDVSVLLNPDNGLGNALANFSN-AKAEGR
TH_1009|M.thermoresistible__bu      NLFAALAAG-DYIDFGPAADIYDVSAILNPDTGLANLLANFSDDATVEGR
MAB_2806|M.abscessus_ATCC_1997      ELFAQLGSA--YSSMGPVKDVYDVGLILDPNKGLANLLANITG-AKSEKT
MUL_4015|M.ulcerans_Agy99           HLYSDLGQPGTYTDFGDGASIYNVSVLLDPNQGLANLLANLKE-ASVTGS
MMAR_4152|M.marinum_M               HLYSDLGQPGTYTDFGDGASIYNVSVLLDPNQGLANLLANLKE-ASVTGS
Mb1301c|M.bovis_AF2122/97           HLYSDLGQPGTYTDFGNGTSIYNVSVLLDPNKGLANLLANLKD-ASVAGS
Rv1270c|M.tuberculosis_H37Rv        HLYSDLGQPGTYTDFGNGASIYNVSVLLDPNKGLANLLANLKD-ASVAGS
                                     *:: :       . *   .:*:*. :*:*: **.* ***:.  ..    

Mflv_3724|M.gilvum_PYR-GCK          ETVEGTQTVRVTGEVSADAVNKIAP---QIGATGPVPGTAWVAEEGDHKL
Mvan_2692|M.vanbaalenii_PYR-1       EEVKGAQTVRVTGEVSADAVNKIAP---QIAATGPVPGTAWITEDGDHEL
MSMEG_3070|M.smegmatis_MC2_155      ESINGTEAVRVKGNVSADAVNKIAP---ALKADGPVPGTAWITED-DHTL
MLBr_00557|M.leprae_Br4923          DSINGQSAVRISGNVSADAVNKIAP---PFNATQPMPATVWIQETGDHQL
MAV_3367|M.avium_104                ETINGQSTIRISGNVSADAVNKIMP---QFNATQPVPSTVWVQETGDHQL
TH_1009|M.thermoresistible__bu      ETINGVRTLHVTGTVTPEAVNAIAP---QIGAEAPVPAGAWIRADGARDL
MAB_2806|M.abscessus_ATCC_1997      ETIDGVDSVLVTGTMSKDALNTFTG---GTTLTADIPAKAWIQKDGNHAL
MUL_4015|M.ulcerans_Agy99           EQVNGVATTKITGNSAADDIATLAGSRLTSADVTTVPTTVWIATDGSSHL
MMAR_4152|M.marinum_M               EQVDGVATTKITGNSAADDIATLAGSRLTSADVTTVPTTVWIATDGSSHL
Mb1301c|M.bovis_AF2122/97           QQADGVATTKITGNSSADDIATLAGSRLTSEDVKTVPTTVWIASDGSSHL
Rv1270c|M.tuberculosis_H37Rv        QQADGVATTKITGNSSADDIATLAGSRLTSEDVKTVPTTVWIASDGSSHL
                                    :  .*  :  :.*  : : :  :            :*  .*:       *

Mflv_3724|M.gilvum_PYR-GCK          MQVRLE-PSPGNSVTMTLSKWGEPVTVDKPAV--
Mvan_2692|M.vanbaalenii_PYR-1       MQARLE-PSPGNSVTMTLSQWGEPVTVDKPAV--
MSMEG_3070|M.smegmatis_MC2_155      LQAQLE-PTPGNSVTMTLSDWGKQVNVTKPAA--
MLBr_00557|M.leprae_Br4923          AQIRIDNKSSGNSVQMTLSNWDEPVQVTKPQVS-
MAV_3367|M.avium_104                VQANLQ-KSSGNSVQVTLSNWGEQVQVTKPPVSS
TH_1009|M.thermoresistible__bu      VQAQLE-PDSGTTVTMTLSEWNKPVTVVKPEV--
MAB_2806|M.abscessus_ATCC_1997      TKISVD-TSPGNTIEMSLSDWGKPVTVDKPAQ--
MUL_4015|M.ulcerans_Agy99           VQIKIL-PTPATSVTLTMSDWGKQVTATKPV---
MMAR_4152|M.marinum_M               VQIKIL-PTPATSVTLTMSDWGKQVTATKPV---
Mb1301c|M.bovis_AF2122/97           VQIQIA-PTKDTSVTLTMSDWGKQVTATKPV---
Rv1270c|M.tuberculosis_H37Rv        VQIQIA-PTKDTSVTLTMSDWGKQVTATKPV---
                                     :  :      .:: :::*.*.: * . **