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M. ulcerans Agy99 MUL_4007 (sixA)

annotation: phosphohistidine phosphatase SixA
coordinates: 4477041 - 4477544
length: 167

MSDRHTLLLMRHAKSQYPPGVADHERPLAPRGRREAGLAGDWLRGNAPAVDEVLCSTAIRTRETLARSGI
DAPVHYSQRLYGAVPGTLIGEINRIGEDVATLLVVGHEPTMSAVALGLAGATGTDAAAAERLSAKFPTSA
IAVLQVAGRWEDLELGGAALITFHVPR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4007sixA-100% (167)phosphohistidine phosphatase SixA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1307c-5e-6371.52% (158) hypothetical protein Mb1307c
M. gilvum PYR-GCKMflv_2254-7e-5158.14% (172) putative phosphohistidine phosphatase, SixA
M. tuberculosis H37RvRv1276c-2e-6372.15% (158) hypothetical protein Rv1276c
M. leprae Br4923MLBr_01117-2e-5363.58% (162) hypothetical protein MLBr_01117
M. abscessus ATCC 19977MAB_1419c-3e-4856.97% (165) putative phosphoglycerate/bisphosphoglycerate mutase
M. marinum MMMAR_4144sixA3e-9299.40% (167) phosphohistidine phosphatase SixA
M. avium 104MAV_1425-2e-6268.86% (167) phosphoglycerate mutase family protein
M. smegmatis MC2 155MSMEG_5006-1e-5968.07% (166) phosphohistidine phosphatase
M. thermoresistible (build 8)TH_1851-1e-5260.47% (172) CONSERVED HYPOTHETICAL PROTEIN
M. vanbaalenii PYR-1Mvan_4437-8e-5662.79% (172) putative phosphohistidine phosphatase, SixA

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2254|M.gilvum_PYR-GCK          MVSVRHSYCRAALRQVCGRAPACPTVNGMSDRLRTLLLLRHAKSDYP---
Mvan_4437|M.vanbaalenii_PYR-1       ----------------------------MSDRHRTLVLLRHAKSDYP---
MSMEG_5006|M.smegmatis_MC2_155      --------------------------------MATLLLMRHAKSDYP---
TH_1851|M.thermoresistible__bu      ----------------------------MSDPFRTLVLLRHGKSAYP---
MUL_4007|M.ulcerans_Agy99           -----------------------------MSDRHTLLLMRHAKSQYP---
MMAR_4144|M.marinum_M               -----------------------------MSDRHTLLLMRHAKSQYP---
Mb1307c|M.bovis_AF2122/97           --------------------------------------MRHAKSAYP---
Rv1276c|M.tuberculosis_H37Rv        --------------------------------------MRHAKSAYP---
MLBr_01117|M.leprae_Br4923          --------------------------------------MRHAKSSYPRGF
MAV_1425|M.avium_104                -----------------------------MTGRRTLLLMRHAKSDYP---
MAB_1419c|M.abscessus_ATCC_199      ---------------------------MPDDAKRTLILMRHAKSAYP---
                                                                          :**.** **   

Mflv_2254|M.gilvum_PYR-GCK          -DGVVDHDRPLASRGVREAALAGDWIRSTIGDIDAVLCSTATRTRQTLEQ
Mvan_4437|M.vanbaalenii_PYR-1       -DGVVDHDRPLAPRGVREGALAGEWIRANVGAVDAVLCSTATRTRQTLER
MSMEG_5006|M.smegmatis_MC2_155      -DGVVDHERPLAPRGVREAALAGDWIRANAPGIDAVLCSTATRTRQTLAR
TH_1851|M.thermoresistible__bu      -PDCADRDRPLAERGIREAGLAGDWLRAHVPPVDAVLCSPATRTRQTFDR
MUL_4007|M.ulcerans_Agy99           -PGVADHERPLAPRGRREAGLAGDWLRGNAPAVDEVLCSTAIRTRETLAR
MMAR_4144|M.marinum_M               -PGVADHERPLAPRGRREAGLAGDWLRGNAPAVDEVLCSTAIRTRETLAR
Mb1307c|M.bovis_AF2122/97           -DGIADHDRPLAPRGIREAGLAGGWLRANLPAVDAVLCSTATRARQTLAH
Rv1276c|M.tuberculosis_H37Rv        -DGIADHDRPLAPRGIREAGLAGGWLRANLPAVDAVLCSTATRARQTLAH
MLBr_01117|M.leprae_Br4923          PDHIADHDRRLAPRGVREASLAGGWLRTNVPAIEKVLCSTAMRARETLTH
MAV_1425|M.avium_104                -DGVADHDRPLAPRGIRQAGLAGDWLRAGAPAIDAVLCSTATRTRETLRN
MAB_1419c|M.abscessus_ATCC_199      -PGVDDHQRPLNLRGTRQAAQAGTWLQDHFNRIDAVLCSTATRTRATLTQ
                                         *::* *  ** *:.. ** *::     :: ****.* *:* *: .

Mflv_2254|M.gilvum_PYR-GCK          TGITAP-VQFVDRIYDATAGILIEEVNGAQARFGEDVSTLLVIGHEPVMS
Mvan_4437|M.vanbaalenii_PYR-1       TGITAP-VQYVDRIYDATPGIVIEEINDVQSRFGEVVSTLLVIGHEPVMS
MSMEG_5006|M.smegmatis_MC2_155      TGIDAP-TEYVEKIYDAVPGTVIGEINDVVSRFGTQPDTVLVVGHEPAMS
TH_1851|M.thermoresistible__bu      TRLTAP-VHYAERLYDATPGTVIDVINGVAAHFDTDIRTLLVIGHEPALS
MUL_4007|M.ulcerans_Agy99           SGIDAP-VHYSQRLYGAVPGTLIGEIN----RIGEDVATLLVVGHEPTMS
MMAR_4144|M.marinum_M               SGIDAP-VHYSQRLYGAVPGTLIGEIN----RIGEDVATLLVVGHEPTMS
Mb1307c|M.bovis_AF2122/97           TGIDAP-ARYAERLYGAAPGTVIEEIN----RVGDNVTSLLVVGHEPTTS
Rv1276c|M.tuberculosis_H37Rv        TGIDAP-ARYAERLYGAAPGTVIEEIN----RVGDNVTTLLVVGHEPTTS
MLBr_01117|M.leprae_Br4923          SGIEAP-VRYTERLYRADPDTVIKEIK----AISDEVTTSLIVSHEPTIS
MAV_1425|M.avium_104                THIEAP-VRYSERLYASTPGIVIDEIN----TVGDDVSTLLVIGHEPTMS
MAB_1419c|M.abscessus_ATCC_199      TGIHSQLVRFSDKLYDSTPGITLGEIN----AVPDSAVTVLVVGHEPTTS
                                    : : :  ..: :::* : ..  :  ::     .     : *::.***. *

Mflv_2254|M.gilvum_PYR-GCK          SVALGLADERSGNGPVADKISAKYPTSSVAVLRSSAPWEQWALRGAELID
Mvan_4437|M.vanbaalenii_PYR-1       ALALSLADEPSSDTPAYQQISAKFPTSAVAVLRTATPWASLALRGAELVD
MSMEG_5006|M.smegmatis_MC2_155      SVALGLDDG--ANVAVAEEISQKFPTSAIAVLRFDGPWDELALGGAQLVT
TH_1851|M.thermoresistible__bu      RVALGLSDG--GNATAAQRISEKFPTSAIAVLRTAADWDELALQGAALVA
MUL_4007|M.ulcerans_Agy99           AVALGLAGATGTDAAAAERLSAKFPTSAIAVLQVAGRWEDLELGGAALIT
MMAR_4144|M.marinum_M               EVALGLAGATGTDAAAAERLSAKFPTSAIAVLQVAGRWEDLELGGAALIT
Mb1307c|M.bovis_AF2122/97           ALAIVLASISGTDAAVAERISEKFPTSGIAVLRVAGHWADVEPGCAALVG
Rv1276c|M.tuberculosis_H37Rv        ALAIVLASISGTDAAVAERISEKFPTSGIAVLRVAGHWADVEPGCAALVG
MLBr_01117|M.leprae_Br4923          AVALALTG-SGTNNDAAQRISTKFPTSGIAVLNVAGRWQHLELESAELVA
MAV_1425|M.avium_104                ALALGLGGGRGANPAAAERISNKFPTSAIAVLAVPCRWTELELGAATLSD
MAB_1419c|M.abscessus_ATCC_199      QLALALADAGTSSAEAANRIATKFPTSAIAVLTTRSPWARLELGGASLTT
                                     :*: * .    .  . :.:: *:***.:***     *       * *  

Mflv_2254|M.gilvum_PYR-GCK          FHTAR
Mvan_4437|M.vanbaalenii_PYR-1       FHVPR
MSMEG_5006|M.smegmatis_MC2_155      FHVPR
TH_1851|M.thermoresistible__bu      FHVPR
MUL_4007|M.ulcerans_Agy99           FHVPR
MMAR_4144|M.marinum_M               FHVPR
Mb1307c|M.bovis_AF2122/97           FHVPR
Rv1276c|M.tuberculosis_H37Rv        FHVPR
MLBr_01117|M.leprae_Br4923          FHVPR
MAV_1425|M.avium_104                FVVAR
MAB_1419c|M.abscessus_ATCC_199      FHVPR
                                    * ..*