For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. ulcerans Agy99 MUL_3625 (-)

annotation: 16S ribosomal RNA methyltransferase RsmE
coordinates: 4023645 - 4024406
length: 253

VATLFYVDTVPEAGELAALDGDEGFHAATVRRIRPGEQLVLGDGAGELARCVVEHAARDGLTARVLQRWS
VAPVRPAVTVVQALPKSERSELAVELATEAGADAFLAWQAARCVANWGGARADKGLRRWRSAVRSAARQS
RRAHIPPVEGVLSTAALIRRITAEAQAGAMVLALHESATDRLVETAVAQAKSLVLVVGPEGGIAPEEMDA
LAGAGAVSVRLGPTVLRTSTAAAVALGALGVLTGRWDSAASP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_3625--100% (253)16S ribosomal RNA methyltransferase RsmE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2393c-1e-11178.97% (252) 16S ribosomal RNA methyltransferase RsmE
M. gilvum PYR-GCKMflv_2703-2e-8268.02% (247) hypothetical protein Mflv_2703
M. tuberculosis H37RvRv2372c-1e-11178.97% (252) 16S ribosomal RNA methyltransferase RsmE
M. leprae Br4923MLBr_00626-1e-10171.76% (255) 16S ribosomal RNA methyltransferase RsmE
M. abscessus ATCC 19977MAB_1667-1e-7559.29% (253) hypothetical protein MAB_1667
M. marinum MMMAR_3682-1e-13698.81% (252) hypothetical protein MMAR_3682
M. avium 104MAV_2024-1e-10979.05% (253) hypothetical protein MAV_2024
M. smegmatis MC2 155MSMEG_4502-1e-8866.53% (248) hypothetical protein MSMEG_4502
M. thermoresistible (build 8)TH_1932-5e-8364.75% (244) conserved hypothetical protein
M. vanbaalenii PYR-1Mvan_3835-5e-8668.57% (245) hypothetical protein Mvan_3835

CLUSTAL 2.0.9 multiple sequence alignment


MUL_3625|M.ulcerans_Agy99           -MVATLFYVDTVPEAGELAALDGDEGFHAATVRRIRPGEQLVLGDGAGEL
MMAR_3682|M.marinum_M               -MVATLFYVDTVPEAGELAALDGDEGFHAATVRRIRPGEQLVLGDGAGEL
Mb2393c|M.bovis_AF2122/97           -MVAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRL
Rv2372c|M.tuberculosis_H37Rv        -MVAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRL
MLBr_00626|M.leprae_Br4923          -MVSTLFYVDALPDTGTVAVVGGDEGFHAVTVRRIRPGEELVLGDGVGGL
MAV_2024|M.avium_104                -MVATLFYTDELPDAGSLAVLGGDEGFHAATVRRIRPGERLVLGDGAGGL
MSMEG_4502|M.smegmatis_MC2_155      -MSAALFYVDVLPGAGELAVVDGDEGHHAANVRRIRVGERIDLSDGAGTL
Mflv_2703|M.gilvum_PYR-GCK          --MRSLFYVDSLPGPGELAVVDGDEGHHAATVCRTRVGEHLDLSDGAGAV
Mvan_3835|M.vanbaalenii_PYR-1       --MRSLFYVDVVPAPGDLAVVDGEEGHHAATVCRTRPGEELDLADGAGTV
TH_1932|M.thermoresistible__bu      -VSRALFYIDTVPAVGDTAVVDGDEGHHAANVRRIRVGEEIDLGDGAGVI
MAB_1667|M.abscessus_ATCC_1997      MAAATIFYVPRVPSAGEQVLLDGDEGHHAARVLRMRVGEPVMVCDGAGEV
                                         :**   :*  *  . :.*:**.**. * * * ** : : **.* :

MUL_3625|M.ulcerans_Agy99           ARCVVEHAARDGLTARVLQRWSVAPVRPAVTVVQALPKSERSELAVELAT
MMAR_3682|M.marinum_M               ARCVVEHAARDGLTARVLQRWSVAPVRPAVTVVQALPKSERSELAVELAT
Mb2393c|M.bovis_AF2122/97           ARCVVEQAGRGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELAT
Rv2372c|M.tuberculosis_H37Rv        ARCVVEQAGRGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELAT
MLBr_00626|M.leprae_Br4923          AHCLVERAGRDGLYARVLGHWTVAPGLPPATVVQALPKAERSELAIEMAT
MAV_2024|M.avium_104                ARCEVEHAGRDGLRARVLERWTVAPPNPPVTVVQALPKSERSELAVELAT
MSMEG_4502|M.smegmatis_MC2_155      AHCVVENTAKGSVSARITEQVTLPPARPSVTVVQALPKSDRSELAIELAT
Mflv_2703|M.gilvum_PYR-GCK          AHCVVEDVAKGRLSARVQDRILVPVPTPAVTVVQALPKSDRSELAIELAT
Mvan_3835|M.vanbaalenii_PYR-1       AHCVVEDVAKGRLTARVQDRHLVAPPRPTVTVVQALPKSERSELAVELAT
TH_1932|M.thermoresistible__bu      AHCVVEEAVRGRLAARVLDRRTVDLPTPTVTVVQALPKSDRAELAVETAT
MAB_1667|M.abscessus_ATCC_1997      GDGVVASVDRTGLAIEVTGRWSVAAVNPKVTVVQALPKSDRSDLAVDLAV
                                    .   *  . :  :  .:  :  :    * .********::*::**:: *.

MUL_3625|M.ulcerans_Agy99           EAGADAFLAWQAARCVANWGGA-RADKGLRRWRSAVRSAARQSRRAHIPP
MMAR_3682|M.marinum_M               EAGADAFLAWQAARCVANWGGA-RADKGLRRWRSAARSAARQSRRAHIPP
Mb2393c|M.bovis_AF2122/97           EAGADAFLAWQAARCVANWDGA-RVDKGLRRWRAVVRSAARQSRRARIPP
Rv2372c|M.tuberculosis_H37Rv        EAGADAFLAWQAARCVANWDGA-RVDKGLRRWRAVVRSAARQSRRARIPP
MLBr_00626|M.leprae_Br4923          EAGADAFVAWQSDRCVASWYGV-RVDKGLRRWRAVARAAARQSRRAHIPS
MAV_2024|M.avium_104                EAGADGFLAWQAARCVANWHGP-RVDKGLRRWRAVAKAAARQSRRPHIPT
MSMEG_4502|M.smegmatis_MC2_155      EAGADAFVAWQSARCVARWDGP-KADKGLRRWSAVARSAARQSRRAYIPT
Mflv_2703|M.gilvum_PYR-GCK          EAGADAFLGWQAARCVARWDGAAKVDKGLRRWRAVARSAARQSRRPHIPE
Mvan_3835|M.vanbaalenii_PYR-1       EAGADAFIAWQASRCVARWDGAAKVDKGLRRWRAVARSAARQSRRPYIPD
TH_1932|M.thermoresistible__bu      EAGADAFLAWQAARCVARWDGPQKVDKGLRRWRAVIRSAARQSRRAHIPA
MAB_1667|M.abscessus_ATCC_1997      EAGADEVIPWQAQRCVSRWDAH-KAEKGRRRWEAVAQAASRQSRRAHVPS
                                    ***** .: **: ***: * .  :.:** *** :. ::*:*****. :* 

MUL_3625|M.ulcerans_Agy99           VEGVLSTAALIRRITAEAQAGAMVLALHESATDRLV----ETAVAQAKSL
MMAR_3682|M.marinum_M               VEGVLSTAALIRRITAEAQAGAMVLALHESATDRLV----DTAVAQAKSL
Mb2393c|M.bovis_AF2122/97           VDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIV----DIAAAQAGSL
Rv2372c|M.tuberculosis_H37Rv        VDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIV----DIAAAQAGSL
MLBr_00626|M.leprae_Br4923          VDGVLTTAALLQRIRDEVAAGATVLALHESATDRLSDVFADISVAQANSL
MAV_2024|M.avium_104                VDGVLSTASLTSRIRDEVAAGAVVLALHESATDRLT----DVPVAQAKSL
MSMEG_4502|M.smegmatis_MC2_155      VTGVESTRDLLRRI---ASTDSVVLALHESATAPFA----EIPVAQSDSV
Mflv_2703|M.gilvum_PYR-GCK          VRGPVSTQDLVGFTR--DAGPATVLVLHESATRPLT----DADLTAR-SL
Mvan_3835|M.vanbaalenii_PYR-1       VDGVVSTRDLVESTR--CAEPGTVLVLHESATRPLA----DAAAGQNDPL
TH_1932|M.thermoresistible__bu      VGGVVSTAELTARVADDVAGGAVALVLHEAAAVPLT----AVGWQPVEAV
MAB_1667|M.abscessus_ATCC_1997      VPELHSTAQLAELVGARAAGGAVVLVLHESAESGLG--ALGARLSSASSV
                                    *    :*  *           . .*.*** *   :             .:

MUL_3625|M.ulcerans_Agy99           VLVVGPEGGIAPEEMDALAGAGAVSVRLGPTVLRTSTAAAVALGALGVLT
MMAR_3682|M.marinum_M               VLVVGPEGGIAPEEMDALAGAGAVSVRLGPTVLRTSTAAAVALGALGVLT
Mb2393c|M.bovis_AF2122/97           MLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLT
Rv2372c|M.tuberculosis_H37Rv        MLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLT
MLBr_00626|M.leprae_Br4923          VLLVGPEGGIAPDEIAALTEAGAVAVRLGPTVLRSSTAAAVALGALGVLT
MAV_2024|M.avium_104                FLVIGPEGGIADDELAALRQAGALSVRLGPQVLRTSTAAAVALGALGVLT
MSMEG_4502|M.smegmatis_MC2_155      ILIIGPEGGIADDEIAALTDAGAHAVRLGPTVLRTSTAAAVALGALGALT
Mflv_2703|M.gilvum_PYR-GCK          TLVVGPEGGVADEELAALTDAGAMAVRLGPTVLRTSTAAAVALGALGVLT
Mvan_3835|M.vanbaalenii_PYR-1       TLIVGPEGGVADDELAALTDAGAVAVRLGPTVLRTSTAAAVALGALGVLT
TH_1932|M.thermoresistible__bu      TLIVGPEGGITDDEIAELQEAGARAVRLGPTVLRTSTAAAVALGAIGVLT
MAB_1667|M.abscessus_ATCC_1997      VLIVGPEGGVADEELRILADAGAAPVRLGPTVLRTSSAAAVALGALGVLT
                                     *::*****:: :*:  *  *** .***** ***:*:********:*.**

MUL_3625|M.ulcerans_Agy99           GRWDSAASP---------
MMAR_3682|M.marinum_M               ERWDSAASL---------
Mb2393c|M.bovis_AF2122/97           SRWDASASDCEYCDVTRR
Rv2372c|M.tuberculosis_H37Rv        SRWDASASDCEYCDVTRR
MLBr_00626|M.leprae_Br4923          SRWDASSIL---------
MAV_2024|M.avium_104                PRWDDAASP---------
MSMEG_4502|M.smegmatis_MC2_155      SRWNI-------------
Mflv_2703|M.gilvum_PYR-GCK          GRWSDQTPRG--------
Mvan_3835|M.vanbaalenii_PYR-1       SRWS--------------
TH_1932|M.thermoresistible__bu      PRWR--------------
MAB_1667|M.abscessus_ATCC_1997      DRWAAGPLVHR-------
                                     **