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M. ulcerans Agy99 MUL_3411 (fadE22)

annotation: acyl-CoA dehydrogenase FadE22
coordinates: 3778248 - 3780413
length: 721

GIALTDDHRELAEVARAFLTSQKARWAARSLLDSPDESRPPFWQDMVELGWLGLHIDERHGGSGYGLPEL
VVVVEELGRAVAPGPFVPTVIASAVLAKEGSDEQQTRLLPGLIDGTVTAGIGLDGNVRVENGVASGDAGI
VLGAGLAELLLVAAGDDVLVLDRGRSGVSVEVPDNFDPTRRSGRVRLHEVKVSAQDLLSGARAAALARAR
TVLAAEAVGGAADCVDAAVAYAKVRQQFGRTIATFQAVKHHCANMLVAAESGIAAVWDAARAATEDEEQF
QLIAAVAALLAFPAYARNAELNIQVHGGIGFTWEHDAHLHLRRALVDAALLGADVPARDVFERTAAGATR
ENSLDLPAEAEELRTQIRADAVEIAALDKAAQLDKLIETGYVMPHWPKPWGRAADAVEQLVIEEEFRKAA
IKRPDYSITGWVILTLIQHGTAWQIERFVEKALRQEEIWCQLFSEPEAGSDAASVKTRATRVDGGWKING
QKVWTSGAQYCARGLATVRTDPDVPKHAGITTVIIDMKSPGVEVRPLRQITGGSEFNEVFFNDVFVPDED
VVGTPNSGWTVARATLGNERVSIGGSGGYYEGLAAKLVKLAQNGADRLAGAEIRVGYFLVEDHALRLLNL
RRAARSVEGAGPGPEGNVTKLKLAEHMVEGAAISAALLGTEIALLDGPGAVIGRMVMGARGMAIAGGTSE
VTRNQIAERILGMPRDPLIN*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_3411fadE22-100% (721)acyl-CoA dehydrogenase FadE22
M. ulcerans Agy99MUL_1194fadE6e-15041.30% (736) acyl-CoA dehydrogenase FadE6
M. ulcerans Agy99MUL_4144fadE34e-13641.83% (722) acyl-CoA dehydrogenase FadE34

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3087cfadE22b0.085.83% (600) acyl-CoA dehydrogenase
M. gilvum PYR-GCKMflv_0441-0.054.21% (725) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv3061cfadE220.085.02% (721) acyl-CoA dehydrogenase FADE22
M. leprae Br4923MLBr_00737fadE251e-1825.52% (384) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_4336-1e-13841.23% (730) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_1625fadE220.099.03% (721) acyl-CoA dehydrogenase FadE22
M. avium 104MAV_3935-0.085.85% (721) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_0603-1e-15041.86% (743) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_3278-0.076.93% (724) PUTATIVE acyl-CoA dehydrogenase FadE22
M. vanbaalenii PYR-1Mvan_0226-0.052.69% (725) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0441|M.gilvum_PYR-GCK          MSKTAS----ASKLAITDDHQDLAAAVTGQLDRLKALVLARATLDAADTD
Mvan_0226|M.vanbaalenii_PYR-1       MSKTVSATVTASRLAITDDHQDLAAAVSGQLTRLQTPAKARAALAG----
Mb3087c|M.bovis_AF2122/97           --------------------------------------------------
Rv3061c|M.tuberculosis_H37Rv        -----------MGIALTDDHRELSGVARAFLTSQKVRWAARASLDA----
MUL_3411|M.ulcerans_Agy99           -----------MGIALTDDHRELAEVARAFLTSQKARWAARSLLDS----
MMAR_1625|M.marinum_M               -----------MGIALTDDHRELAEVARAFLTSQKARWAARSLLDS----
MAV_3935|M.avium_104                -----------MGIALTDDHRELAEVARGFLTSQKARWAARSLLDA----
TH_3278|M.thermoresistible__bu      -----------MAIALTDDHRELAEVARSFLTSQQARAAARALLDA----
MAB_4336|M.abscessus_ATCC_1997      -----------MPIAINSEHVALADSAHAFVERVVPTELLHETLETPLPW
MSMEG_0603|M.smegmatis_MC2_155      -----------MPIAILSEHIDLADSVKSFVARVAPSDVLHEALETPLET
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0441|M.gilvum_PYR-GCK          GASNPSDLWSAATGLGWTGLALAEDVGGSGFGLAELAVVVECLGHQLAPG
Mvan_0226|M.vanbaalenii_PYR-1       GSTHPADIWSAATELGWTGLALPEDVGGSGFGLEELAVVIECLGSQLAPG
Mb3087c|M.bovis_AF2122/97           --------------------------------------------------
Rv3061c|M.tuberculosis_H37Rv        AGDARPPFWQNLAELGWLGLHIDERHGGSGYGLSELVVVIEELGRAVAPG
MUL_3411|M.ulcerans_Agy99           PDESRPPFWQDMVELGWLGLHIDERHGGSGYGLPELVVVVEELGRAVAPG
MMAR_1625|M.marinum_M               PDESRPPFWQDMVELGWLGLHIDERHGGSGYGLPELVVVVEELGRAVAPG
MAV_3935|M.avium_104                TDEPRPGFWPNLVELGWLGLHIDEEYGGSGFGLPELVVVVEELGRAVAPG
TH_3278|M.thermoresistible__bu      DDEARPPFWSELAGLGWLGLHISEKHGGSGYGLPELVVVVEELGRAVAPG
MAB_4336|M.abscessus_ATCC_1997      P----PPFWKSAADQGLTSVHLAESVGGQGFGALELAIVVAEFGRGAVPG
MSMEG_0603|M.smegmatis_MC2_155      PRANPPSYWKAAADQGLQGVHLSESVGGQGFGILELAIVLAEFGYGAVPG
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0441|M.gilvum_PYR-GCK          PFLTSVSAAVVIDRCAPDSVRAELLPGSASGDTVAALGISGTVAVGAD--
Mvan_0226|M.vanbaalenii_PYR-1       PFLSSAAASVVIDRSAPDSVRAELLPVLAGGETVAALGVSGSVVVGTD--
Mb3087c|M.bovis_AF2122/97           ------------------------------------MGLDSQVQVTD---
Rv3061c|M.tuberculosis_H37Rv        LFVPTVIASAVVAKEGTDDQRARLLPALIDGTLTAGVGLDSQVQVTD---
MUL_3411|M.ulcerans_Agy99           PFVPTVIASAVLAKEGSDEQQTRLLPGLIDGTVTAGIGLDGNVRVEN---
MMAR_1625|M.marinum_M               PFVPTVIASAVLAKEGSDEQQTRLLPGLIDGTVTAGIGLDGNLRVEN---
MAV_3935|M.avium_104                PFVPTVIASAVIAKNGTAEQKSRLLPGLIDGTVTAGIGLDSRVRLGD---
TH_3278|M.thermoresistible__bu      PFVPTVVASAVLADAGSDEQRDRLLPGLVDGSVVAAVGLGGDLRVEGPVE
MAB_4336|M.abscessus_ATCC_1997      PFVPSVIASALISAHDPDHP---LLSDLASGASIATFSSTSSFTATPAGD
MSMEG_0603|M.smegmatis_MC2_155      PFVPSAIASALISAHDPDAK---VLSELASGDAIAAYALDSTLTATRQGD
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0441|M.gilvum_PYR-GCK          -NTATGECATVLGAPDASLLVLVAGDD----VVIVDAG----DDGVTVTR
Mvan_0226|M.vanbaalenii_PYR-1       -LIVSGESPVVLAAPDASVLVLTAGED----VVILDAGPASAAGGVTVTP
Mb3087c|M.bovis_AF2122/97           -GVADGEAGIVLGAGLAELLLVAAGDD----VLVLERG----RKGVSVDV
Rv3061c|M.tuberculosis_H37Rv        -GVADGEAGIVLGAGLAELLLVAAGDD----VLVLERG----RKGVSVDV
MUL_3411|M.ulcerans_Agy99           -GVASGDAGIVLGAGLAELLLVAAGDD----VLVLDRG----RSGVSVEV
MMAR_1625|M.marinum_M               -GVASGDAGIVLGAGLAELLLVAAGDE----VLVLDRG----RSGVSVEV
MAV_3935|M.avium_104                -GVADGEAGILLGAGLAGLLLIAAGDD----VLVLERD----RDGVSVDV
TH_3278|M.thermoresistible__bu      AATASGTAGVVLGAGRADLLLLRCGDD----VLIVDRT----APGVTVEV
MAB_4336|M.abscessus_ATCC_1997      GLSVDGQARSVLSATSATYVVAPVAIDSDRRWVVLSAD------DVTLDS
MSMEG_0603|M.smegmatis_MC2_155      GLVIRGEVRAVPAAAQASILVLPVAIDSGEEWVVLDAD------QLEIEP
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0441|M.gilvum_PYR-GCK          LDCLDTTRSIGSVTLDGVAVPADRILRGAARD-ARTVFRTLTAAEAVGVS
Mvan_0226|M.vanbaalenii_PYR-1       LDCLDPTRSIGSVTLRDVPVAADRVLRGAARN-ARTVFRILAAAEAVGVS
Mb3087c|M.bovis_AF2122/97           PENFDPTRRSGRVRLDNVRVTTDDILLGAYES-ALARARTLLAAEAVGGA
Rv3061c|M.tuberculosis_H37Rv        PENFDPTRRSGRVRLDNVRVTTDDILLGAYES-ALARARTLLAAEAVGGA
MUL_3411|M.ulcerans_Agy99           PDNFDPTRRSGRVRLHEVKVSAQDLLSGARAA-ALARARTVLAAEAVGGA
MMAR_1625|M.marinum_M               PDNFDPTRRSGRVRLHEVKVSAQDLLPGARAA-ALARARTVLAAEAVGGA
MAV_3935|M.avium_104                PDNFDPTRRSGRVRLDNVRVSDADVLAGARPS-ALARARTLLAAEAVGGA
TH_3278|M.thermoresistible__bu      PTNLDPTRRSGRVTLTGVAVT--DVLPGAAET-ALALARTLFAAEAAGGA
MAB_4336|M.abscessus_ATCC_1997      QQSVDPLRPVAHVTATAVQVPADRVLSNLTDARATSIISTIVSAEAVGVA
MSMEG_0603|M.smegmatis_MC2_155      VRSVDPLRPLAHVRANAVEVADERVLSNLSRPLARALMSTLLSAESIGVA
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0441|M.gilvum_PYR-GCK          WAALDMAVEYAKVREQFGRTIGTFQAVKHHAANMLVSAETATAAVWDAAR
Mvan_0226|M.vanbaalenii_PYR-1       WAALDMAVGYAKVREQFGRTIGTFQAVKHHAANMLVAAEVATAATWDAAR
Mb3087c|M.bovis_AF2122/97           ADCVDSAVAYAKVRQQFGRTIATFQAVKHHCANMLVAAESAIAAVWDAAR
Rv3061c|M.tuberculosis_H37Rv        ADCVDSAVAYAKVRQQFGRTIATFQAVKHHCANMLVAAESAIAAVWDAAR
MUL_3411|M.ulcerans_Agy99           ADCVDAAVAYAKVRQQFGRTIATFQAVKHHCANMLVAAESGIAAVWDAAR
MMAR_1625|M.marinum_M               ADCVDAAVAYAKVRQQFGRTIATFQAVKHHCANMLVAAESGIAAVWDAAR
MAV_3935|M.avium_104                SDCVDAAVAYAKVRQQFGRTIATFQAVKHHCANMLVGAESGIAAVWDAAR
TH_3278|M.thermoresistible__bu      VECVETAVEYAKVRRQFGRVIGTFQAVKHHCANMAVAAESAIATVWDAAR
MAB_4336|M.abscessus_ATCC_1997      RWATDTASEYAKVREQFGRPIGQFQGIKHKCATMAAVTERATAAVWDAAR
MSMEG_0603|M.smegmatis_MC2_155      RWATDTAAGYAKIREQFGRPIGQFQAVKHKCANMVAVTERATAAVWDAAR
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0441|M.gilvum_PYR-GCK          ADDV------DSAWF--AAAVAAALAIKAQVFNAQNNIQLHGGIGFTWEH
Mvan_0226|M.vanbaalenii_PYR-1       ADDL------DSAWF--AGAVAAALAIRAQVFNAQNNIQLHGGIGFTWEH
Mb3087c|M.bovis_AF2122/97           AAAE------DEEQFRLAAAVAAALAFPAYARNAELNIQVHGGIGFTWEH
Rv3061c|M.tuberculosis_H37Rv        AAAE------DEEQFRLAAAVAAALAFPAYARNAELNIQVHGGIGFTWEH
MUL_3411|M.ulcerans_Agy99           AATE------DEEQFQLIAAVAALLAFPAYARNAELNIQVHGGIGFTWEH
MMAR_1625|M.marinum_M               AATE------DEEQFQLIAAVAALLAFPAYARNAELNIQVHGGIGFTWEH
MAV_3935|M.avium_104                AAGE------DEDQFHLIAAVAAALAFPAYVRNAELNIQVHGGIGFTWEH
TH_3278|M.thermoresistible__bu      AAAG------DPAEFRLMAAAAAALAFPAYVHNAELNIQVHGGIGYTWEH
MAB_4336|M.abscessus_ATCC_1997      ALDDADEN---PGVVEFAASVAATLAPAAAQQCAQDCIQVHGGIGYTWEH
MSMEG_0603|M.smegmatis_MC2_155      ALDEVREKGTEGTHFGFAAAVAATLAPAAAQQCTQDCIQVHGGIGFTWEH
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0441|M.gilvum_PYR-GCK          DAHLYLRRARTLAALMADGVDPLIDIVDGQRTGRAHGASFTLPPEADEYR
Mvan_0226|M.vanbaalenii_PYR-1       DSHLYLRRARTLAALMADGVDPLLDIVDGQRNGRAHGASFTLPPESEEYR
Mb3087c|M.bovis_AF2122/97           DAHLHLRRALVTVGLFG-GDAPVRDVFERTAAGVTRAISLDLPAQAEELR
Rv3061c|M.tuberculosis_H37Rv        DAHLHLRRALVTVGLFG-GDAPVRDVFERTAAGVTRAISLDLPAQAEELR
MUL_3411|M.ulcerans_Agy99           DAHLHLRRALVDAALLG-ADVPARDVFERTAAGATRENSLDLPAEAEELR
MMAR_1625|M.marinum_M               DAHLHLRRALVDAALLG-AEAPARDVFERTAAGATRENSLDLPAEAEELR
MAV_3935|M.avium_104                DAHLHLRRAVVTAALFG-GDAPAADVFERTAAGTVRDNSLDLPPEAEELR
TH_3278|M.thermoresistible__bu      DAHLHLRRALAVRGVLG-GDGPAADVHALTAAGVTRENSLDLPPEAEEMR
MAB_4336|M.abscessus_ATCC_1997      DAHIYYRRALGLTAALGRSGGAPATVVRTAVEHGLRKVDIDLAPETEALR
MSMEG_0603|M.smegmatis_MC2_155      DTNVYYRRALLLAACFGRAADHPQQVVDTATATGMRPVDIDLDPETEKLR
MLBr_00737|M.leprae_Br4923          --------------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAP
                                                   .. .      :             :   .: :   

Mflv_0441|M.gilvum_PYR-GCK          TQAREAAEAVRRLPAEQQRDYLVDSGYLVPHWPKPWG--RAADVLEQLVI
Mvan_0226|M.vanbaalenii_PYR-1       SQAREAAAKVRSLPAGQQRDFLVESGYLVPHWPQPWG--RAANVLEQLVI
Mb3087c|M.bovis_AF2122/97           ARIRSDAAEIAALEKDAQRDKLIETGYVMPHWPRPWG--RAAGAVEQLVI
Rv3061c|M.tuberculosis_H37Rv        ARIRSDAAEIAALEKDAQRDKLIETGYVMPHWPRPWG--RAAGAVEQLVI
MUL_3411|M.ulcerans_Agy99           TQIRADAVEIAALDKAAQLDKLIETGYVMPHWPKPWG--RAADAVEQLVI
MMAR_1625|M.marinum_M               TQIRADAVEIAALDKAAQLDKLIETGYVMPHWPKPWG--RAADAVEQLVI
MAV_3935|M.avium_104                TKIRADAAAIAALDKDAQLDKLIETGYVMPHWPKPWG--RAADAVEQLVI
TH_3278|M.thermoresistible__bu      GRIRADIEEIAALDGNAQRDRLIETGYIMPHWPKPWG--RGADAVEQLVI
MAB_4336|M.abscessus_ATCC_1997      AEIRAEVAALKEIPSGKRNTAIAEGGWVLPYLPTPWG--RAASPVEQVII
MSMEG_0603|M.smegmatis_MC2_155      DEIRAEVAALKAIPSEERTAAIAEGGWVQPHLPKPWG--RDATPVEQIII
MLBr_00737|M.leprae_Br4923          ---HAADVDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVI
                                       :                 :   *:   : *  :*          ::*

Mflv_0441|M.gilvum_PYR-GCK          EEEF--AAIERADMGITGWVALTIAQAGTDEQRERWVEPVLRGQVMWCQL
Mvan_0226|M.vanbaalenii_PYR-1       EEEF--AGVDRPDMGITGWVALTIAQAGTDDQRERWVEPVLRGQVMWCQL
Mb3087c|M.bovis_AF2122/97           EEEFSAAGIERPDYSITGWVILTLIQHGTPWQIERFVEKALRQQEIWCQL
Rv3061c|M.tuberculosis_H37Rv        EEEFSAAGIERPDYSITGWVILTLIQHGTPWQIERFVEKALRQQEIWCQL
MUL_3411|M.ulcerans_Agy99           EEEFRKAAIKRPDYSITGWVILTLIQHGTAWQIERFVEKALRQEEIWCQL
MMAR_1625|M.marinum_M               EEEFRKAAIKRPDYSITGWVILTLIQHGTAWQIERFVEKALRQEEIWCQL
MAV_3935|M.avium_104                EEEFRAAGIKRPDYGITGWVILTLIQHGTPWQIERFVEKALRKDEIWCQL
TH_3278|M.thermoresistible__bu      DEEFARAGIERPDYSITGWVILTLIQHGTPSQIERFVEKALRQEEIWCQL
MAB_4336|M.abscessus_ATCC_1997      SQEFLTGKVRRPQLGIATWLVPSIVAYGTEEQKQRFLPPTFRGEMMWCQL
MSMEG_0603|M.smegmatis_MC2_155      AQEFTTGRVKRPQMGIASWIIPSIVAFGTDEQKQRFLPPTFRGEMIWCQL
MLBr_00737|M.leprae_Br4923          EEVARVDASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYA
                                     :            .:       :   *:    :: :        : .  

Mflv_0441|M.gilvum_PYR-GCK          FSEPGAGSDAAAVRTSAKKVDGGWRVTGQKVWTSLAHMCQWGLATVRTDP
Mvan_0226|M.vanbaalenii_PYR-1       FSEPGAGSDAAAVRTSAKKVDGGWRVTGQKVWTSLAHLCQWGLATVRTDP
Mb3087c|M.bovis_AF2122/97           FSEPDAGSDAASVKTRATRVEGGWKINGQKVWTSGAQYCARGLATVRTDP
Rv3061c|M.tuberculosis_H37Rv        FSEPDAGSDAASVKTRATRVEGGWKINGQKVWTSGAQYCARGLATVRTDP
MUL_3411|M.ulcerans_Agy99           FSEPEAGSDAASVKTRATRVDGGWKINGQKVWTSGAQYCARGLATVRTDP
MMAR_1625|M.marinum_M               FSEPEAGSDAASVKTRATRVDGGWKINGQKVWTSGAQYCARGLATVRTDP
MAV_3935|M.avium_104                FSEPDAGSDAASIKTRATRVEGGWKINGQKVWTSGAHYCARGLATVRTDP
TH_3278|M.thermoresistible__bu      FSEPDAGSDAAAVKTRAIRVDGGWKVTGQKVWTSGAHYCRRGLATVRTDP
MAB_4336|M.abscessus_ATCC_1997      FSEPGAGSDLAGLSTKAVKVEGGWRLTGQKIWTSVAQFADWGACLARTDP
MSMEG_0603|M.smegmatis_MC2_155      FSEPGAGSDLASLTTRAVKVDGGWRITGQKIWTTGAQFSAWGALLARTDP
MLBr_00737|M.leprae_Br4923          LSEREAGSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDP
                                    :**  **** *.: * *    ..* :.* * * : .  .      . ***

Mflv_0441|M.gilvum_PYR-GCK          DAAKHAGVTMMAIDMNADGVTVNPLRGLTGD--SHFNEVFFDDVFVPDAD
Mvan_0226|M.vanbaalenii_PYR-1       DAPKHAGVTMMAIDMNAEGVTVNPLRGITGD--SHFNEVFFDDVFVPDAD
Mb3087c|M.bovis_AF2122/97           DAPKHAGITTVIIDMLAPGVEVRPLRQITGD--SEFNEVFFNDVFVPDED
Rv3061c|M.tuberculosis_H37Rv        DAPKHAGITTVIIDMLAPGVEVRPLRQITGD--SEFNEVFFNDVFVPDED
MUL_3411|M.ulcerans_Agy99           DVPKHAGITTVIIDMKSPGVEVRPLRQITGG--SEFNEVFFNDVFVPDED
MMAR_1625|M.marinum_M               DVPKHAGITTVIIDMKSPGVEVRPLRQITGG--SEFNEVFFNDVFVPDED
MAV_3935|M.avium_104                DAPKHAGITTVIVDMKAPEVEVRPLRQITGG--SDFNEVFFNDLFVPDED
TH_3278|M.thermoresistible__bu      DAPKHAGITTMIIDMHAPGVEVRPLRMITGG--AEFNEVFFNDVFVPDED
MAB_4336|M.abscessus_ATCC_1997      SAPKHNGITYFLVDMKSEGVTVRPLREMTGG--ALFNEVFIDDVFVPDEL
MSMEG_0603|M.smegmatis_MC2_155      DAPKHQGITYFLLDMKSPGVEVKPLRELTGN--AMFNTVFIDDVFVPDDM
MLBr_00737|M.leprae_Br4923          DK-GANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDR
                                    .     *:: . :.     . : * .   *   :  . ::::.  :*.  

Mflv_0441|M.gilvum_PYR-GCK          VVGDVNKGWLVARATLGNERVSIGGGSGGVTGTTPDHLIKLLDSSPDRAP
Mvan_0226|M.vanbaalenii_PYR-1       VVGDVNKGWLVARATLGNERISIGGGSGGPVGTTPDHLIKLLDSSPATSA
Mb3087c|M.bovis_AF2122/97           VVGAPNSGWTVARATLGNERVSIGG-SGSYYEAMAAKLVQLVQRRSDAFA
Rv3061c|M.tuberculosis_H37Rv        VVGAPNSGWTVARATLGNERVSIGG-SGSYYEAMAAKLVQLVQRRSDAFA
MUL_3411|M.ulcerans_Agy99           VVGTPNSGWTVARATLGNERVSIGG-SGGYYEGLAAKLVKLAQNGADRLA
MMAR_1625|M.marinum_M               VVGTPNSGWTVARATLGNERVSIGG-SGGYYEGLAAKLVKLAQNGADRLA
MAV_3935|M.avium_104                VVGTPNSGWTVARATLGNERVSIGG-SGSFYEGLADQLVQLAQQRPDRLA
TH_3278|M.thermoresistible__bu      VVGEPNTGWTVARATLGNERVSIGG-GSGARVFAATSLIPLVQRHADRLA
MAB_4336|M.abscessus_ATCC_1997      VVGEVNRGWEVSRNTLTAERVSIGS-SDLPFLASLDDLVAFVGTH-DLGE
MSMEG_0603|M.smegmatis_MC2_155      VLGEVNRGWEVSRNTLTNERVSIGS-SEPPFLANLDQFVQFLRDG-QFDQ
MLBr_00737|M.leprae_Br4923          IIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGE
                                    ::*  . *: .:  **   * :**. .           :           

Mflv_0441|M.gilvum_PYR-GCK          MFVRQAGEVIAEIHSLRLLNLRRATRAISGAEPGPEGNVTKLVVAESGQH
Mvan_0226|M.vanbaalenii_PYR-1       MYVRQAGEVIAELHSLRLLNLRRATRAIAGAEPGPEGNVTKLLVAESGQR
Mb3087c|M.bovis_AF2122/97           GAPIRVGAFLAEDHALRLLNLRRAARSVEGAGPGPEGNITKLKVAEHMIE
Rv3061c|M.tuberculosis_H37Rv        GAPIRVGAFLAEDHALRLLNLRRAARSVEGAGPGPEGNITKLKVAEHMIE
MUL_3411|M.ulcerans_Agy99           GAEIRVGYFLVEDHALRLLNLRRAARSVEGAGPGPEGNVTKLKLAEHMVE
MMAR_1625|M.marinum_M               GAEIRVGYFLAEDHALRLLNLRRAARSVEGAGPGPEGNVTKLKLAEHMVE
MAV_3935|M.avium_104                GGKIRVGSYLAEETALRLLNLRRAARSVEGTGPGPEGNVTKLKLAEHMVE
TH_3278|M.thermoresistible__bu      GAEVRVGTFLAEEHALRLLNLRRAVRSIEGAGPGPEGNITKLKLAEHMNE
MAB_4336|M.abscessus_ATCC_1997      VARDRAGQLIAEGHGVKLLNLRSTLLTLAGGDPMPSAAVSKLLGMRTGQG
MSMEG_0603|M.smegmatis_MC2_155      IEQNHAGQLIAEGHAAKVLNLRSTLLTLAGGDAMPNAAISKLLSMKTGQG
MLBr_00737|M.leprae_Br4923          SISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCF
                                          .  :        ::         .  .        :        

Mflv_0441|M.gilvum_PYR-GCK          LTELAFELAG--TAAVVEQMP----QLTRSYLGNRAMTIAGGTSEITRNT
Mvan_0226|M.vanbaalenii_PYR-1       LTELAFELAG--TAAVVGQTP----QLTRSYLGNRAMTIAGGTSEITRNT
Mb3087c|M.bovis_AF2122/97           GAAIAAALWGPEIALLDGPGR----VIGRTVMGARGMAIAGGTSEVTRNQ
Rv3061c|M.tuberculosis_H37Rv        GAAIAAALWGPEIALLDGPGR----VIGRTVMGARGMAIAGGTSEVTRNQ
MUL_3411|M.ulcerans_Agy99           GAAISAALLGTEIALLDGPGA----VIGRMVMGARGMAIAGGTSEVTRNQ
MMAR_1625|M.marinum_M               GAAISAALLGPEIALLDGPGA----VIGRMVMGARGMAIAGGTSEVTRNQ
MAV_3935|M.avium_104                GAAIMAALLGPEVALTDGPGA----LSGRLMMGARGMAIAGGTSEVTRNQ
TH_3278|M.thermoresistible__bu      RAAIMAGLLGPELALLDGDTA----VAGLMVLGARGMAIAGGTSEVTRNQ
MAB_4336|M.abscessus_ATCC_1997      YAEFVVNHFGQDGAIGDSEQEQ--GRWADYLLASRATTIYGGTSEVQLNI
MSMEG_0603|M.smegmatis_MC2_155      YAEFAVSTFGTDAAIGDPQEEP--GRWAEYLLASRATTIYGGTTEVQLNI
MLBr_00737|M.leprae_Br4923          ASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVV
                                     : :                              :   *  **.::    

Mflv_0441|M.gilvum_PYR-GCK          IAERILGLPRDPLLR
Mvan_0226|M.vanbaalenii_PYR-1       IAERILGLPRDPLLR
Mb3087c|M.bovis_AF2122/97           IAERILGMPRDPLIS
Rv3061c|M.tuberculosis_H37Rv        IAERILGMPRDPLIS
MUL_3411|M.ulcerans_Agy99           IAERILGMPRDPLIN
MMAR_1625|M.marinum_M               IAERILGMPRDPLIN
MAV_3935|M.avium_104                IAERILGMPRDPLIN
TH_3278|M.thermoresistible__bu      IAERILGLPRDPLIT
MAB_4336|M.abscessus_ATCC_1997      IAERLLGLPRDP---
MSMEG_0603|M.smegmatis_MC2_155      IAERLLGLPRDP---
MLBr_00737|M.leprae_Br4923          MSRALLR--------
                                    ::. :*