For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SLVDTAESWLAAHYDDLVGWRRHIHRYPELGRQEFATTQFVAERLADAGLNPKILPGGTGLTCDFGPEHQ PRIALRADMDALPMAERTGAPYASTMPNIAHACGHDGHTAILLGTALALATVPELPVGVRLIFEAAEELM PGGAIDAIAAGALTGVSRIFALHCDPRLEVGRVAVRQGPITSAADHIEITLYSPGGHTSRPHLTADLVYG LGTLITGLPGVLSRRVDPRNSTVLVWGAVNAGVAANAIPQTGVLAGTVRTASRQTWIDLEEIIRESITAL LSPLAIEHTLQYRRGVPPVVNEEVSTHILTHAIEAVSPDALADTRQSGGGEDFSWYLEEVPGAMGRLGVW SGDGPQLDLHQPTFDLDERALGIGLRVMVNIIEQAAAF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2671 | amiA1 | - | 100% (389) | N-acyl-L-amino acid amidohydrolase AmiA1 |
| M. ulcerans Agy99 | MUL_2672 | amiB1 | 1e-11 | 26.94% (271) | amidohydrolase AmiB1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3333c | amiA1 | 0.0 | 90.72% (388) | N-acyl-L-amino acid amidohydrolase |
| M. gilvum PYR-GCK | Mflv_4826 | - | 0.0 | 80.31% (381) | amidohydrolase |
| M. tuberculosis H37Rv | Rv3305c | amiA1 | 0.0 | 90.72% (388) | N-acyl-L-amino acid amidohydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3658c | - | 1e-174 | 74.35% (386) | putative peptidase/amidohydrolase |
| M. marinum M | MMAR_1221 | amiA1 | 0.0 | 99.49% (389) | N-acyl-L-amino acid amidohydrolase AmiA1 |
| M. avium 104 | MAV_4281 | - | 0.0 | 87.66% (389) | amidohydrolase |
| M. smegmatis MC2 155 | MSMEG_1703 | - | 0.0 | 81.27% (379) | amidohydrolase |
| M. thermoresistible (build 8) | TH_1760 | - | 0.0 | 82.06% (379) | POSSIBLE N-ACYL-L-AMINO ACID AMIDOHYDROLASE AMIA1 |
| M. vanbaalenii PYR-1 | Mvan_1612 | - | 0.0 | 80.89% (382) | amidohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2671|M.ulcerans_Agy99 MS--LVDTAESWLAAHYDDLVGWRRHIHRYPELGRQEFATTQFVAERLAD
MMAR_1221|M.marinum_M MS--LVDTAESWLAAHYDDLVGWRRHIHRYPELGRQEFATTQFVAERLAD
Mb3333c|M.bovis_AF2122/97 MS--LADAAESWLAAHHDDLVGWRRHIHRYPELGRQEYATTQFVAERLAD
Rv3305c|M.tuberculosis_H37Rv MS--LADAAESWLAAHHDDLVGWRRHIHRYPELGRQEYATTQFVAERLAD
MAV_4281|M.avium_104 MS--LADAATSWLAAHNQDLIEWRRHIHRYPELGRQEYATTQFVAERLAE
Mflv_4826|M.gilvum_PYR-GCK MSV-LRHAAARWLSEHYDDLVGWRRHIHRHPELGRQEFATTQFVASLLAD
Mvan_1612|M.vanbaalenii_PYR-1 MSV-LRHAAARWLSEHHDDLVGWRRHIHRHPELGRQEFATTQFVASLLAD
TH_1760|M.thermoresistible__bu MSV-LRHAVARWLSRHQDDLVAWRRHIHAHPELGRQEFATTQFVAERLAD
MSMEG_1703|M.smegmatis_MC2_155 MSVDLGAITDRWLAEHYDEMVAWRRHIHAHPELGRQEFATTEFVARHLAE
MAB_3658c|M.abscessus_ATCC_199 MSESLSAVAEQWLAENTDALVRWRRHIHEHPELARQEHATTEYVAARLAE
** * . **: : : :: ****** :***.***.***::** **:
MUL_2671|M.ulcerans_Agy99 AGLNPKILPGGTGLTCDFGPEHQPRIALRADMDALPMAERTGAPYASTMP
MMAR_1221|M.marinum_M AGLNPKILPGGTGLTCDFGPEHQPRIALRADMDALPMAERTGAPYASTMP
Mb3333c|M.bovis_AF2122/97 AGLNPKVLPGGTGLTCDFGPQHQPRIALRADMDALPMAERTGAPYASTMP
Rv3305c|M.tuberculosis_H37Rv AGLNPKVLPGGTGLTCDFGPQHQPRIALRADMDALPMAERTGAPYASTMP
MAV_4281|M.avium_104 AGLNPKVLPGGTGLTCDLGPEHEPRIALRADMDALPMAERTGAPYASTMP
Mflv_4826|M.gilvum_PYR-GCK AGLNPKVLPGGTGLTCDFGPEDGPRVALRADMDALPMSERTGLPFSSEVA
Mvan_1612|M.vanbaalenii_PYR-1 AGLNPKVLPGGTGLTCDFGPDDAPRVALRADMDALPMAERTGLAFASEVP
TH_1760|M.thermoresistible__bu AGLNPKVLPGGTGLICDLGPDHTPRVALRADMDALPMPERTGAPYASTVP
MSMEG_1703|M.smegmatis_MC2_155 AGLNPKVLPGGTGLTCDFGPEDGPRVALRADMDALPMADRTGAPYASTVP
MAB_3658c|M.abscessus_ATCC_199 AGLNPKVLPGGTGVTCDFGPEDGPRVALRADMDALPMQERTGAAYSSTVP
******:******: **:**:. **:*********** :*** .::* :.
MUL_2671|M.ulcerans_Agy99 NIAHACGHDGHTAILLGTALALATVPELPVGVRLIFEAAEELMPGGAIDA
MMAR_1221|M.marinum_M NIAHACGHDGHTAILLGTALALATVPELPVGVRLIFQAAEELMPGGAIDA
Mb3333c|M.bovis_AF2122/97 NVAHACGHDAHTAILLGAALALASVPELPVGVRLIFQAAEELMPGGAIDA
Rv3305c|M.tuberculosis_H37Rv NVAHACGHDAHTAILLGAALALASVPELPVGVRLIFQAAEELMPGGAIDA
MAV_4281|M.avium_104 NVAHACGHDAHTAILLGTALVLASVPELPVGVRLIFQAAEELMPGGAIDA
Mflv_4826|M.gilvum_PYR-GCK GVAHACGHDGHTSVLLGAALALASAPELPIGVRLIFQAAEELMPGGAIDA
Mvan_1612|M.vanbaalenii_PYR-1 DVAHACGHDAHTAVLLGAALAMASETELPVGVRLIFQAAEELMPGGALDA
TH_1760|M.thermoresistible__bu NVAHACGHDAHTAMLLGAALALNTVPELPIGVRLIFQAAEELMPGGALDA
MSMEG_1703|M.smegmatis_MC2_155 NVAHACGHDAHTAVLLGTAKVLASATELPVGVRLIFQAAEELMPGGAIDA
MAB_3658c|M.abscessus_ATCC_199 NVAHACGHDAHTAILLGAAMALNSAPSLPSGVRLIFQPAEEVMPGGAIDV
.:*******.**::***:* .: : ..** ******:.***:*****:*.
MUL_2671|M.ulcerans_Agy99 IAAGALTGVSRIFALHCDPRLEVGRVAVRQGPITSAADHIEITLYSPGGH
MMAR_1221|M.marinum_M IAAGALTGVSRIFALHCDPRLEVGRVAVRQGPITSAADHIEITLYSPGGH
Mb3333c|M.bovis_AF2122/97 IAAGALAGVSRIFALHCDPRLEVGKVAVRQGPITSAADSIEITLYSPGGH
Rv3305c|M.tuberculosis_H37Rv IAAGALAGVSRIFALHCDPRLEVGKVAVRQGPITSAADSIEITLYSPGGH
MAV_4281|M.avium_104 IAAGAITGVSRIFALHCDPRLEVGQIAVRHGPITSAADQIEITLYSPGGH
Mflv_4826|M.gilvum_PYR-GCK IAAGALTGVSRIFALHCDPHLAVGQVAVKAGPITSAADHIEVTLHSPGGH
Mvan_1612|M.vanbaalenii_PYR-1 IAAGALTGVSRIYALHCDPHLAVGRVAVKAGPITSAADHVEVTLHSPGGH
TH_1760|M.thermoresistible__bu IAAGVLNGVSRIFALHCDPRLQVGRVATRPGPITSAADHVEVTLQSKGGH
MSMEG_1703|M.smegmatis_MC2_155 VAAGALNGVTRIFALHCDPRLRVGRVATKPGPITSAADSIEITLHSPGGH
MAB_3658c|M.abscessus_ATCC_199 VAAGAMAGVTRIFALHCDPRLEVGKVAIRAGAITSAADTVEITLHSPGGH
:***.: **:**:******:* **::* : *.****** :*:** * ***
MUL_2671|M.ulcerans_Agy99 TSRPHLTADLVYGLGTLITGLPGVLSRRVDPRNSTVLVWGAVNAGVAANA
MMAR_1221|M.marinum_M TSRPHLTADLVYGLGTLITGLPGVLSRRVDPRNSTVLVWGAVNAGVAANA
Mb3333c|M.bovis_AF2122/97 TSRPHLTADLVYGLGTLVTGLPGVLSRRIDPRNSTVLVWGAVNAGMAANA
Rv3305c|M.tuberculosis_H37Rv TSRPHLTADLVYGLGTLVTGLPGVLSRRIDPRNSTVLVWGAVNAGMAANA
MAV_4281|M.avium_104 TSRPHLTADLVYGLGTLITGLPGVLSRRIDPRNGTVLVWGAVNAGVAANA
Mflv_4826|M.gilvum_PYR-GCK TSRPHLTGDLVYGMGTLITGVPGILSRRIDPRNSTVMVWGAVHAGVAANA
Mvan_1612|M.vanbaalenii_PYR-1 TSRPHLTGDLVYGLGTLITGVPGILSRRIDPRNSTVMVWGAVHAGVAANA
TH_1760|M.thermoresistible__bu TSRPHLTGDLVYALGTLITGVPGVLSRRIDPRNGTVMVWGAVNAGVAANA
MSMEG_1703|M.smegmatis_MC2_155 TSRPHLTGDLVYGLGTLITGLPGVLSRRIDPRHNTVMVWGAVNAGVAANA
MAB_3658c|M.abscessus_ATCC_199 TSRPHLTADLVYGLGTVITGLPGVLSRRIDPRAGTVMVWGAVNAGQAANA
*******.****.:**::**:**:****:*** .**:*****:** ****
MUL_2671|M.ulcerans_Agy99 IPQTGVLAGTVRTASRQTWIDLEEIIRESITALLSPLAIEHTLQYRRGVP
MMAR_1221|M.marinum_M IPQTGVLAGTVRTASRQTWIDLEEIIRESITALLSPLAIEHTLQYRRGVP
Mb3333c|M.bovis_AF2122/97 IPQTGVLSGTVRTASRQTWVDLEELVRQAISALLLPLAIEHTLQYRRGVP
Rv3305c|M.tuberculosis_H37Rv IPQTGVLSGTVRTASRQTWVDLEELVRQAISALLLPLAIEHTLQYRRGVP
MAV_4281|M.avium_104 IPQTGVLAGTVRTASRQTWVGLEEVIRETVSGLLAPLGIEHTLQYRRGVP
Mflv_4826|M.gilvum_PYR-GCK IPQTGTMAGTIRTASRETWLTLEDIVTDAVASLLAPLGIEYVVQYRRGVP
Mvan_1612|M.vanbaalenii_PYR-1 IPQTGTLAGTIRTASRETWLTLEDIVQEAISSLLSPLDIEHVVQYRRGVP
TH_1760|M.thermoresistible__bu IPQTGTLAGTIRTASRSTWLTLEAIVSETVSSLLAPLGVEHSLQYRRGVP
MSMEG_1703|M.smegmatis_MC2_155 IPQIGTLAGTIRTASRDTWLTLEAIVDETVTALLAPLNIEHSLNYRRGVP
MAB_3658c|M.abscessus_ATCC_199 IPQIGSLAGTVRTGSRDVWITLEDTVRDVIAGLLAPLRIDYTLNYRRGVP
*** * ::**:**.**..*: ** : : ::.** ** ::: ::******
MUL_2671|M.ulcerans_Agy99 PVVNEEVSTHILTHAIEAVSPDALADTRQSGGGEDFSWYLEEVPGAMGRL
MMAR_1221|M.marinum_M PVVNEEVSTHILTHAIEAVSPDALADTRQSGGGEDFSWYLEEVPGAMGRL
Mb3333c|M.bovis_AF2122/97 PVVNEEISTRILAHAIEAIGPGVLADTRQSGGGEDFSWYLEEVPGAMARL
Rv3305c|M.tuberculosis_H37Rv PVVNEEISTRILAHAIEAIGPGVLADTRQSGGGEDFSWYLEEVPGAMARL
MAV_4281|M.avium_104 PVVNEDVSTRILTHAIEALGPDALADTRQSGGGEDFSWYLEEIPGAMARL
Mflv_4826|M.gilvum_PYR-GCK PVVNEEASTRILTHAIEAIGPDVLADTQQSGGGEDFSWYLEEVPGAMARL
Mvan_1612|M.vanbaalenii_PYR-1 PVVNEEIATRIMTHAIEAIGPDVLADTRQSGGGEDFSWYLEEVPGAMARL
TH_1760|M.thermoresistible__bu PVVNEEQSTRILTRAIEAVGPNVLADTRQSGGGEDFSWYLEEVPGAMARL
MSMEG_1703|M.smegmatis_MC2_155 PVVNEDVSTRMLTHAIEAVGPDVLANTHQSGGGEDFSWYLEEIPGAMGRL
MAB_3658c|M.abscessus_ATCC_199 PVINEAESTHIFVRAIQDIGLDALAETTQSGGGEDFSWYLEEVPGAMARL
**:** :*:::.:**: :. ..**:* **************:****.**
MUL_2671|M.ulcerans_Agy99 GVWSGDGPQLDLHQPTFDLDERALGIGLRVMVNIIEQAAAF---
MMAR_1221|M.marinum_M GVWSGDGPQLDLHQPTFDLDERALGIGVRVMVNIIEQAAAF---
Mb3333c|M.bovis_AF2122/97 GVWSGDGLQLDLHQPTFDIDERALAIGLRVMVNIIEQAAAH---
Rv3305c|M.tuberculosis_H37Rv GVWSGDGLQLDLHQPTFDIDERALAIGLRVMVNIIEQAAAH---
MAV_4281|M.avium_104 GVWPGVGPQLDLHQPTFNLDERALAIGVRVMANIVEQSALFQVF
Mflv_4826|M.gilvum_PYR-GCK GVWSGQGPQLDLHQPTFDLDERALGVGVRLLVNLVEQSAVVP--
Mvan_1612|M.vanbaalenii_PYR-1 GVWSGRGPQLDLHQPTFDLDERALGVGVRLMVNLVEQSASAQ--
TH_1760|M.thermoresistible__bu GVWSGQGPQLDLHQPTFDLDERALPVGVRVFVNLVEQCAA----
MSMEG_1703|M.smegmatis_MC2_155 GVWSGQGPQLDLHQPTFDLDERALGVGVRTMVNIVAAARQ----
MAB_3658c|M.abscessus_ATCC_199 GVWSGSGPQLDIHQPNFDIDERALGVGVRTLVNLVEQSAIQNPV
***.* * ***:***.*::***** :*:* :.*:: .