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M. marinum M MMAR_1221 (amiA1)

annotation: N-acyl-L-amino acid amidohydrolase AmiA1
coordinates: 1483754 - 1484923
length: 389

MSLVDTAESWLAAHYDDLVGWRRHIHRYPELGRQEFATTQFVAERLADAGLNPKILPGGTGLTCDFGPEH
QPRIALRADMDALPMAERTGAPYASTMPNIAHACGHDGHTAILLGTALALATVPELPVGVRLIFQAAEEL
MPGGAIDAIAAGALTGVSRIFALHCDPRLEVGRVAVRQGPITSAADHIEITLYSPGGHTSRPHLTADLVY
GLGTLITGLPGVLSRRVDPRNSTVLVWGAVNAGVAANAIPQTGVLAGTVRTASRQTWIDLEEIIRESITA
LLSPLAIEHTLQYRRGVPPVVNEEVSTHILTHAIEAVSPDALADTRQSGGGEDFSWYLEEVPGAMGRLGV
WSGDGPQLDLHQPTFDLDERALGIGVRVMVNIIEQAAAF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1221amiA1-100% (389)N-acyl-L-amino acid amidohydrolase AmiA1
M. marinum MMMAR_1220amiB13e-1126.94% (271) amidohydrolase AmiB1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3333camiA10.090.72% (388) N-acyl-L-amino acid amidohydrolase
M. gilvum PYR-GCKMflv_4826-0.080.84% (381) amidohydrolase
M. tuberculosis H37RvRv3305camiA10.090.72% (388) N-acyl-L-amino acid amidohydrolase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3658c-1e-17474.87% (386) putative peptidase/amidohydrolase
M. avium 104MAV_4281-0.088.17% (389) amidohydrolase
M. smegmatis MC2 155MSMEG_1703-0.081.79% (379) amidohydrolase
M. thermoresistible (build 8)TH_1760-0.082.59% (379) POSSIBLE N-ACYL-L-AMINO ACID AMIDOHYDROLASE AMIA1
M. ulcerans Agy99MUL_2671amiA10.099.49% (389) N-acyl-L-amino acid amidohydrolase AmiA1
M. vanbaalenii PYR-1Mvan_1612-0.081.41% (382) amidohydrolase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1221|M.marinum_M               MS--LVDTAESWLAAHYDDLVGWRRHIHRYPELGRQEFATTQFVAERLAD
MUL_2671|M.ulcerans_Agy99           MS--LVDTAESWLAAHYDDLVGWRRHIHRYPELGRQEFATTQFVAERLAD
Mb3333c|M.bovis_AF2122/97           MS--LADAAESWLAAHHDDLVGWRRHIHRYPELGRQEYATTQFVAERLAD
Rv3305c|M.tuberculosis_H37Rv        MS--LADAAESWLAAHHDDLVGWRRHIHRYPELGRQEYATTQFVAERLAD
MAV_4281|M.avium_104                MS--LADAATSWLAAHNQDLIEWRRHIHRYPELGRQEYATTQFVAERLAE
Mflv_4826|M.gilvum_PYR-GCK          MSV-LRHAAARWLSEHYDDLVGWRRHIHRHPELGRQEFATTQFVASLLAD
Mvan_1612|M.vanbaalenii_PYR-1       MSV-LRHAAARWLSEHHDDLVGWRRHIHRHPELGRQEFATTQFVASLLAD
TH_1760|M.thermoresistible__bu      MSV-LRHAVARWLSRHQDDLVAWRRHIHAHPELGRQEFATTQFVAERLAD
MSMEG_1703|M.smegmatis_MC2_155      MSVDLGAITDRWLAEHYDEMVAWRRHIHAHPELGRQEFATTEFVARHLAE
MAB_3658c|M.abscessus_ATCC_199      MSESLSAVAEQWLAENTDALVRWRRHIHEHPELARQEHATTEYVAARLAE
                                    **  *   .  **: : : :: ****** :***.***.***::**  **:

MMAR_1221|M.marinum_M               AGLNPKILPGGTGLTCDFGPEHQPRIALRADMDALPMAERTGAPYASTMP
MUL_2671|M.ulcerans_Agy99           AGLNPKILPGGTGLTCDFGPEHQPRIALRADMDALPMAERTGAPYASTMP
Mb3333c|M.bovis_AF2122/97           AGLNPKVLPGGTGLTCDFGPQHQPRIALRADMDALPMAERTGAPYASTMP
Rv3305c|M.tuberculosis_H37Rv        AGLNPKVLPGGTGLTCDFGPQHQPRIALRADMDALPMAERTGAPYASTMP
MAV_4281|M.avium_104                AGLNPKVLPGGTGLTCDLGPEHEPRIALRADMDALPMAERTGAPYASTMP
Mflv_4826|M.gilvum_PYR-GCK          AGLNPKVLPGGTGLTCDFGPEDGPRVALRADMDALPMSERTGLPFSSEVA
Mvan_1612|M.vanbaalenii_PYR-1       AGLNPKVLPGGTGLTCDFGPDDAPRVALRADMDALPMAERTGLAFASEVP
TH_1760|M.thermoresistible__bu      AGLNPKVLPGGTGLICDLGPDHTPRVALRADMDALPMPERTGAPYASTVP
MSMEG_1703|M.smegmatis_MC2_155      AGLNPKVLPGGTGLTCDFGPEDGPRVALRADMDALPMADRTGAPYASTVP
MAB_3658c|M.abscessus_ATCC_199      AGLNPKVLPGGTGVTCDFGPEDGPRVALRADMDALPMQERTGAAYSSTVP
                                    ******:******: **:**:. **:*********** :*** .::* :.

MMAR_1221|M.marinum_M               NIAHACGHDGHTAILLGTALALATVPELPVGVRLIFQAAEELMPGGAIDA
MUL_2671|M.ulcerans_Agy99           NIAHACGHDGHTAILLGTALALATVPELPVGVRLIFEAAEELMPGGAIDA
Mb3333c|M.bovis_AF2122/97           NVAHACGHDAHTAILLGAALALASVPELPVGVRLIFQAAEELMPGGAIDA
Rv3305c|M.tuberculosis_H37Rv        NVAHACGHDAHTAILLGAALALASVPELPVGVRLIFQAAEELMPGGAIDA
MAV_4281|M.avium_104                NVAHACGHDAHTAILLGTALVLASVPELPVGVRLIFQAAEELMPGGAIDA
Mflv_4826|M.gilvum_PYR-GCK          GVAHACGHDGHTSVLLGAALALASAPELPIGVRLIFQAAEELMPGGAIDA
Mvan_1612|M.vanbaalenii_PYR-1       DVAHACGHDAHTAVLLGAALAMASETELPVGVRLIFQAAEELMPGGALDA
TH_1760|M.thermoresistible__bu      NVAHACGHDAHTAMLLGAALALNTVPELPIGVRLIFQAAEELMPGGALDA
MSMEG_1703|M.smegmatis_MC2_155      NVAHACGHDAHTAVLLGTAKVLASATELPVGVRLIFQAAEELMPGGAIDA
MAB_3658c|M.abscessus_ATCC_199      NVAHACGHDAHTAILLGAAMALNSAPSLPSGVRLIFQPAEEVMPGGAIDV
                                    .:*******.**::***:* .: : ..** ******:.***:*****:*.

MMAR_1221|M.marinum_M               IAAGALTGVSRIFALHCDPRLEVGRVAVRQGPITSAADHIEITLYSPGGH
MUL_2671|M.ulcerans_Agy99           IAAGALTGVSRIFALHCDPRLEVGRVAVRQGPITSAADHIEITLYSPGGH
Mb3333c|M.bovis_AF2122/97           IAAGALAGVSRIFALHCDPRLEVGKVAVRQGPITSAADSIEITLYSPGGH
Rv3305c|M.tuberculosis_H37Rv        IAAGALAGVSRIFALHCDPRLEVGKVAVRQGPITSAADSIEITLYSPGGH
MAV_4281|M.avium_104                IAAGAITGVSRIFALHCDPRLEVGQIAVRHGPITSAADQIEITLYSPGGH
Mflv_4826|M.gilvum_PYR-GCK          IAAGALTGVSRIFALHCDPHLAVGQVAVKAGPITSAADHIEVTLHSPGGH
Mvan_1612|M.vanbaalenii_PYR-1       IAAGALTGVSRIYALHCDPHLAVGRVAVKAGPITSAADHVEVTLHSPGGH
TH_1760|M.thermoresistible__bu      IAAGVLNGVSRIFALHCDPRLQVGRVATRPGPITSAADHVEVTLQSKGGH
MSMEG_1703|M.smegmatis_MC2_155      VAAGALNGVTRIFALHCDPRLRVGRVATKPGPITSAADSIEITLHSPGGH
MAB_3658c|M.abscessus_ATCC_199      VAAGAMAGVTRIFALHCDPRLEVGKVAIRAGAITSAADTVEITLHSPGGH
                                    :***.: **:**:******:* **::* : *.****** :*:** * ***

MMAR_1221|M.marinum_M               TSRPHLTADLVYGLGTLITGLPGVLSRRVDPRNSTVLVWGAVNAGVAANA
MUL_2671|M.ulcerans_Agy99           TSRPHLTADLVYGLGTLITGLPGVLSRRVDPRNSTVLVWGAVNAGVAANA
Mb3333c|M.bovis_AF2122/97           TSRPHLTADLVYGLGTLVTGLPGVLSRRIDPRNSTVLVWGAVNAGMAANA
Rv3305c|M.tuberculosis_H37Rv        TSRPHLTADLVYGLGTLVTGLPGVLSRRIDPRNSTVLVWGAVNAGMAANA
MAV_4281|M.avium_104                TSRPHLTADLVYGLGTLITGLPGVLSRRIDPRNGTVLVWGAVNAGVAANA
Mflv_4826|M.gilvum_PYR-GCK          TSRPHLTGDLVYGMGTLITGVPGILSRRIDPRNSTVMVWGAVHAGVAANA
Mvan_1612|M.vanbaalenii_PYR-1       TSRPHLTGDLVYGLGTLITGVPGILSRRIDPRNSTVMVWGAVHAGVAANA
TH_1760|M.thermoresistible__bu      TSRPHLTGDLVYALGTLITGVPGVLSRRIDPRNGTVMVWGAVNAGVAANA
MSMEG_1703|M.smegmatis_MC2_155      TSRPHLTGDLVYGLGTLITGLPGVLSRRIDPRHNTVMVWGAVNAGVAANA
MAB_3658c|M.abscessus_ATCC_199      TSRPHLTADLVYGLGTVITGLPGVLSRRIDPRAGTVMVWGAVNAGQAANA
                                    *******.****.:**::**:**:****:*** .**:*****:** ****

MMAR_1221|M.marinum_M               IPQTGVLAGTVRTASRQTWIDLEEIIRESITALLSPLAIEHTLQYRRGVP
MUL_2671|M.ulcerans_Agy99           IPQTGVLAGTVRTASRQTWIDLEEIIRESITALLSPLAIEHTLQYRRGVP
Mb3333c|M.bovis_AF2122/97           IPQTGVLSGTVRTASRQTWVDLEELVRQAISALLLPLAIEHTLQYRRGVP
Rv3305c|M.tuberculosis_H37Rv        IPQTGVLSGTVRTASRQTWVDLEELVRQAISALLLPLAIEHTLQYRRGVP
MAV_4281|M.avium_104                IPQTGVLAGTVRTASRQTWVGLEEVIRETVSGLLAPLGIEHTLQYRRGVP
Mflv_4826|M.gilvum_PYR-GCK          IPQTGTMAGTIRTASRETWLTLEDIVTDAVASLLAPLGIEYVVQYRRGVP
Mvan_1612|M.vanbaalenii_PYR-1       IPQTGTLAGTIRTASRETWLTLEDIVQEAISSLLSPLDIEHVVQYRRGVP
TH_1760|M.thermoresistible__bu      IPQTGTLAGTIRTASRSTWLTLEAIVSETVSSLLAPLGVEHSLQYRRGVP
MSMEG_1703|M.smegmatis_MC2_155      IPQIGTLAGTIRTASRDTWLTLEAIVDETVTALLAPLNIEHSLNYRRGVP
MAB_3658c|M.abscessus_ATCC_199      IPQIGSLAGTVRTGSRDVWITLEDTVRDVIAGLLAPLRIDYTLNYRRGVP
                                    *** * ::**:**.**..*: **  : : ::.** ** ::: ::******

MMAR_1221|M.marinum_M               PVVNEEVSTHILTHAIEAVSPDALADTRQSGGGEDFSWYLEEVPGAMGRL
MUL_2671|M.ulcerans_Agy99           PVVNEEVSTHILTHAIEAVSPDALADTRQSGGGEDFSWYLEEVPGAMGRL
Mb3333c|M.bovis_AF2122/97           PVVNEEISTRILAHAIEAIGPGVLADTRQSGGGEDFSWYLEEVPGAMARL
Rv3305c|M.tuberculosis_H37Rv        PVVNEEISTRILAHAIEAIGPGVLADTRQSGGGEDFSWYLEEVPGAMARL
MAV_4281|M.avium_104                PVVNEDVSTRILTHAIEALGPDALADTRQSGGGEDFSWYLEEIPGAMARL
Mflv_4826|M.gilvum_PYR-GCK          PVVNEEASTRILTHAIEAIGPDVLADTQQSGGGEDFSWYLEEVPGAMARL
Mvan_1612|M.vanbaalenii_PYR-1       PVVNEEIATRIMTHAIEAIGPDVLADTRQSGGGEDFSWYLEEVPGAMARL
TH_1760|M.thermoresistible__bu      PVVNEEQSTRILTRAIEAVGPNVLADTRQSGGGEDFSWYLEEVPGAMARL
MSMEG_1703|M.smegmatis_MC2_155      PVVNEDVSTRMLTHAIEAVGPDVLANTHQSGGGEDFSWYLEEIPGAMGRL
MAB_3658c|M.abscessus_ATCC_199      PVINEAESTHIFVRAIQDIGLDALAETTQSGGGEDFSWYLEEVPGAMARL
                                    **:**  :*:::.:**: :. ..**:* **************:****.**

MMAR_1221|M.marinum_M               GVWSGDGPQLDLHQPTFDLDERALGIGVRVMVNIIEQAAAF---
MUL_2671|M.ulcerans_Agy99           GVWSGDGPQLDLHQPTFDLDERALGIGLRVMVNIIEQAAAF---
Mb3333c|M.bovis_AF2122/97           GVWSGDGLQLDLHQPTFDIDERALAIGLRVMVNIIEQAAAH---
Rv3305c|M.tuberculosis_H37Rv        GVWSGDGLQLDLHQPTFDIDERALAIGLRVMVNIIEQAAAH---
MAV_4281|M.avium_104                GVWPGVGPQLDLHQPTFNLDERALAIGVRVMANIVEQSALFQVF
Mflv_4826|M.gilvum_PYR-GCK          GVWSGQGPQLDLHQPTFDLDERALGVGVRLLVNLVEQSAVVP--
Mvan_1612|M.vanbaalenii_PYR-1       GVWSGRGPQLDLHQPTFDLDERALGVGVRLMVNLVEQSASAQ--
TH_1760|M.thermoresistible__bu      GVWSGQGPQLDLHQPTFDLDERALPVGVRVFVNLVEQCAA----
MSMEG_1703|M.smegmatis_MC2_155      GVWSGQGPQLDLHQPTFDLDERALGVGVRTMVNIVAAARQ----
MAB_3658c|M.abscessus_ATCC_199      GVWSGSGPQLDIHQPNFDIDERALGVGVRTLVNLVEQSAIQNPV
                                    ***.* * ***:***.*::***** :*:* :.*::  .