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M. ulcerans Agy99 MUL_2627 (purE)

annotation: phosphoribosylaminoimidazole carboxylase catalytic subunit PurE (air carboxylase) (AirC)
coordinates: 2930842 - 2931357
length: 171

AEQPRVAVIMGSDSDWSVMADAAKALAEFDIAMEVRVVSAHRTPQVMFDYARDAAGRGIEVIIAGAGGAA
HLPGMVASATPLPVIGVPVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRMLGSSDPALRA
RIAAFQDQLAQTVQAKDAELQKLAGKLTRD*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. ulcerans Agy99 MUL_2627 purE - 100% (171) phosphoribosylaminoimidazole carboxylase catalytic subunit PurE (air carboxylase) (AirC)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3303c purE 4e-77 85.80% (169) phosphoribosylaminoimidazole carboxylase catalytic subunit
M. gilvum PYR-GCK Mflv_4746 - 7e-65 77.44% (164) phosphoribosylaminoimidazole carboxylase, catalytic subunit
M. tuberculosis H37Rv Rv3275c purE 2e-76 85.21% (169) phosphoribosylaminoimidazole carboxylase catalytic subunit
M. leprae Br4923 MLBr_00736 purE 1e-74 83.04% (171) phosphoribosylaminoimidazole carboxylase
M. abscessus ATCC 19977 MAB_3619c - 5e-64 78.48% (158) phosphoribosylaminoimidazole carboxylase PurE
M. marinum M MMAR_1261 purE 9e-91 100.00% (171) phosphoribosylaminoimidazole carboxylase catalytic subunit
M. avium 104 MAV_4244 purE 3e-77 86.39% (169) phosphoribosylaminoimidazole carboxylase, catalytic subunit
M. smegmatis MC2 155 MSMEG_1820 purE 4e-63 80.26% (152) phosphoribosylaminoimidazole carboxylase, catalytic subunit
M. thermoresistible (build 8) TH_0890 purE 3e-65 79.25% (159) PROBABLE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC
M. vanbaalenii PYR-1 Mvan_1714 - 4e-66 79.75% (163) phosphoribosylaminoimidazole carboxylase, catalytic subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4746|M.gilvum_PYR-GCK          -------------MSSPRVGLIMGSDSDWPVMSDAAEALAEFEVPFEVGV
Mvan_1714|M.vanbaalenii_PYR-1       --------------MTPRVGLIMGSDSDWPVMSEAAEALAEFDVPFEVGV
TH_0890|M.thermoresistible__bu      MGMPTEERLREEQRMRPRVGLIMGSDSDWPVMSEAAEALAEFDVPFEVGV
MSMEG_1820|M.smegmatis_MC2_155      ----------------------MGSDSDWTVMVDAAEALAEFEVPFEVGV
MAB_3619c|M.abscessus_ATCC_199      --------------MSARVGLIMGSDSDWSVMSDAANALAEFEIPFEVGV
MUL_2627|M.ulcerans_Agy99           ------------MAEQPRVAVIMGSDSDWSVMADAAKALAEFDIAMEVRV
MMAR_1261|M.marinum_M               ------------MAEQPRVAVIMGSDSDWSVMADAAKALAEFDIAMEVRV
Mb3303c|M.bovis_AF2122/97           ---------MTPAGERPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRV
Rv3275c|M.tuberculosis_H37Rv        ---------MTPAGERPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRV
MLBr_00736|M.leprae_Br4923          ------------MTRQPRVGVIMGSDSDWSVMQDAAHALAEFDIPIEVRV
MAV_4244|M.avium_104                ----------MSVTEAPRVAVIMGSDSDWSVMADAAAALAEFDVPTEVRV
                                                          *******.** :** *****::. ** *

Mflv_4746|M.gilvum_PYR-GCK          VSAHRTPARMLTYAQEASGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
Mvan_1714|M.vanbaalenii_PYR-1       VSAHRTPARMLSYAADAAGRGLEVIIAGAGGAAHLPGMVASATPLPVIGV
TH_0890|M.thermoresistible__bu      VSAHRTPGRMLDYARGAAGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
MSMEG_1820|M.smegmatis_MC2_155      VSAHRTPGRMLDYAKNAADRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
MAB_3619c|M.abscessus_ATCC_199      VSAHRTPGRMLQYAQSAAGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
MUL_2627|M.ulcerans_Agy99           VSAHRTPQVMFDYARDAAGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
MMAR_1261|M.marinum_M               VSAHRTPQVMFDYARDAAGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
Mb3303c|M.bovis_AF2122/97           VSAHRTPEAMFSYARGAAERGLEVIIAGAGGAAHLPGMVAAATPLPVIGV
Rv3275c|M.tuberculosis_H37Rv        VSAHRTPEAMFSYARGAAERGLEVIIAGAGGAAHLPGMVAAATPLPVIGV
MLBr_00736|M.leprae_Br4923          VSAHRTPAEMFDYARNAVDRSIAVIIAGAGGAAHLPGMVASATPLPVIGV
MAV_4244|M.avium_104                VSAHRTPGVMFDYARDAAGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
                                    *******  *: **  *  *.: *****************:*********

Mflv_4746|M.gilvum_PYR-GCK          PVPLARLDGMDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILGASDNA
Mvan_1714|M.vanbaalenii_PYR-1       PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILGAADGA
TH_0890|M.thermoresistible__bu      PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILAAADSA
MSMEG_1820|M.smegmatis_MC2_155      PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILGATDPQ
MAB_3619c|M.abscessus_ATCC_199      PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAARILGVADTA
MUL_2627|M.ulcerans_Agy99           PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRMLGSSDPA
MMAR_1261|M.marinum_M               PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRMLGSSDPA
Mb3303c|M.bovis_AF2122/97           PVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRMLGAANPQ
Rv3275c|M.tuberculosis_H37Rv        PVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGAGNAGLLAVRMLGAANPQ
MLBr_00736|M.leprae_Br4923          PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILGSSDLQ
MAV_4244|M.avium_104                PVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILGASDPG
                                    ****.****:*********************** ******.*:*. ::  

Mflv_4746|M.gilvum_PYR-GCK          LQQRMIAFQASLEQMVLQKEEALR---QKLLGE----
Mvan_1714|M.vanbaalenii_PYR-1       LRDRMAAYQASLEQMVLQKDEALR---QKLLGD----
TH_0890|M.thermoresistible__bu      LRDRMTKFQADLERMVLAKDEALR---DRLLGGDRKE
MSMEG_1820|M.smegmatis_MC2_155      LRGRMAKFQADLEAMVLEKDAALR---SRLLGDG---
MAB_3619c|M.abscessus_ATCC_199      LRDKVVAFQASMEATVLEKDEALR---RRLLED----
MUL_2627|M.ulcerans_Agy99           LRARIAAFQDQLAQTVQAKDAELQKLAGKLTRD----
MMAR_1261|M.marinum_M               LRARIAAFQDQLAQTVQAKDAELQKLAGKLTRD----
Mb3303c|M.bovis_AF2122/97           LRARIVAFQDRLADVVAAKDAELQRLAGKLTRD----
Rv3275c|M.tuberculosis_H37Rv        LRARIVAFQDRLADVVAAKDAELQRLAGKLTRD----
MLBr_00736|M.leprae_Br4923          LRAQLVAFQDRLADTVRAKDADLQRFRGKLIGD----
MAV_4244|M.avium_104                LRARIVEFQTQLADSVRAKDEALQRLHGKVTGQ----
                                    *: ::  :*  :   *  *:  *:    ::

species	id	gene	e-value	identity (len)	annotation
M. ulcerans Agy99	MUL_2627	purE	-	100% (171)	phosphoribosylaminoimidazole carboxylase catalytic subunit PurE (air carboxylase) (AirC)