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M. smegmatis MC2 155 MSMEG_1820 (purE)

annotation: phosphoribosylaminoimidazole carboxylase, catalytic subunit
coordinates: 1895208 - 1895687
length: 159

MGSDSDWTVMVDAAEALAEFEVPFEVGVVSAHRTPGRMLDYAKNAADRGIEVIIAGAGGAAHLPGMVASA
TPLPVIGVPVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILGATDPQLRGRMAKFQADL
EAMVLEKDAALRSRLLGDG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1820purE-100% (159)phosphoribosylaminoimidazole carboxylase, catalytic subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3303cpurE2e-6277.71% (157) phosphoribosylaminoimidazole carboxylase catalytic subunit
M. gilvum PYR-GCKMflv_4746-2e-7084.81% (158) phosphoribosylaminoimidazole carboxylase, catalytic subunit
M. tuberculosis H37RvRv3275cpurE1e-6177.07% (157) phosphoribosylaminoimidazole carboxylase catalytic subunit
M. leprae Br4923MLBr_00736purE3e-6477.64% (161) phosphoribosylaminoimidazole carboxylase
M. abscessus ATCC 19977MAB_3619c-1e-7084.81% (158) phosphoribosylaminoimidazole carboxylase PurE
M. marinum MMMAR_1261purE3e-6380.26% (152) phosphoribosylaminoimidazole carboxylase catalytic subunit
M. avium 104MAV_4244purE7e-6582.24% (152) phosphoribosylaminoimidazole carboxylase, catalytic subunit
M. thermoresistible (build 8)TH_0890purE2e-7389.17% (157) PROBABLE PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC
M. ulcerans Agy99MUL_2627purE2e-6380.26% (152) phosphoribosylaminoimidazole carboxylase catalytic subunit
M. vanbaalenii PYR-1Mvan_1714-2e-7186.08% (158) phosphoribosylaminoimidazole carboxylase, catalytic subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4746|M.gilvum_PYR-GCK          -------------MSSPRVGLIMGSDSDWPVMSDAAEALAEFEVPFEVGV
Mvan_1714|M.vanbaalenii_PYR-1       --------------MTPRVGLIMGSDSDWPVMSEAAEALAEFDVPFEVGV
TH_0890|M.thermoresistible__bu      MGMPTEERLREEQRMRPRVGLIMGSDSDWPVMSEAAEALAEFDVPFEVGV
MSMEG_1820|M.smegmatis_MC2_155      ----------------------MGSDSDWTVMVDAAEALAEFEVPFEVGV
MAB_3619c|M.abscessus_ATCC_199      --------------MSARVGLIMGSDSDWSVMSDAANALAEFEIPFEVGV
Mb3303c|M.bovis_AF2122/97           ---------MTPAGERPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRV
Rv3275c|M.tuberculosis_H37Rv        ---------MTPAGERPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRV
MMAR_1261|M.marinum_M               ------------MAEQPRVAVIMGSDSDWSVMADAAKALAEFDIAMEVRV
MUL_2627|M.ulcerans_Agy99           ------------MAEQPRVAVIMGSDSDWSVMADAAKALAEFDIAMEVRV
MLBr_00736|M.leprae_Br4923          ------------MTRQPRVGVIMGSDSDWSVMQDAAHALAEFDIPIEVRV
MAV_4244|M.avium_104                ----------MSVTEAPRVAVIMGSDSDWSVMADAAAALAEFDVPTEVRV
                                                          *******.** :** *****::. ** *

Mflv_4746|M.gilvum_PYR-GCK          VSAHRTPARMLTYAQEASGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
Mvan_1714|M.vanbaalenii_PYR-1       VSAHRTPARMLSYAADAAGRGLEVIIAGAGGAAHLPGMVASATPLPVIGV
TH_0890|M.thermoresistible__bu      VSAHRTPGRMLDYARGAAGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
MSMEG_1820|M.smegmatis_MC2_155      VSAHRTPGRMLDYAKNAADRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
MAB_3619c|M.abscessus_ATCC_199      VSAHRTPGRMLQYAQSAAGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
Mb3303c|M.bovis_AF2122/97           VSAHRTPEAMFSYARGAAERGLEVIIAGAGGAAHLPGMVAAATPLPVIGV
Rv3275c|M.tuberculosis_H37Rv        VSAHRTPEAMFSYARGAAERGLEVIIAGAGGAAHLPGMVAAATPLPVIGV
MMAR_1261|M.marinum_M               VSAHRTPQVMFDYARDAAGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
MUL_2627|M.ulcerans_Agy99           VSAHRTPQVMFDYARDAAGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
MLBr_00736|M.leprae_Br4923          VSAHRTPAEMFDYARNAVDRSIAVIIAGAGGAAHLPGMVASATPLPVIGV
MAV_4244|M.avium_104                VSAHRTPGVMFDYARDAAGRGIEVIIAGAGGAAHLPGMVASATPLPVIGV
                                    *******  *: **  *  *.: *****************:*********

Mflv_4746|M.gilvum_PYR-GCK          PVPLARLDGMDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILGASDNA
Mvan_1714|M.vanbaalenii_PYR-1       PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILGAADGA
TH_0890|M.thermoresistible__bu      PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILAAADSA
MSMEG_1820|M.smegmatis_MC2_155      PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILGATDPQ
MAB_3619c|M.abscessus_ATCC_199      PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAARILGVADTA
Mb3303c|M.bovis_AF2122/97           PVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRMLGAANPQ
Rv3275c|M.tuberculosis_H37Rv        PVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGAGNAGLLAVRMLGAANPQ
MMAR_1261|M.marinum_M               PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRMLGSSDPA
MUL_2627|M.ulcerans_Agy99           PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRMLGSSDPA
MLBr_00736|M.leprae_Br4923          PVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILGSSDLQ
MAV_4244|M.avium_104                PVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGARNAGLLAVRILGASDPG
                                    ****.****:*********************** ******.*:*. ::  

Mflv_4746|M.gilvum_PYR-GCK          LQQRMIAFQASLEQMVLQKEEALR---QKLLGE----
Mvan_1714|M.vanbaalenii_PYR-1       LRDRMAAYQASLEQMVLQKDEALR---QKLLGD----
TH_0890|M.thermoresistible__bu      LRDRMTKFQADLERMVLAKDEALR---DRLLGGDRKE
MSMEG_1820|M.smegmatis_MC2_155      LRGRMAKFQADLEAMVLEKDAALR---SRLLGDG---
MAB_3619c|M.abscessus_ATCC_199      LRDKVVAFQASMEATVLEKDEALR---RRLLED----
Mb3303c|M.bovis_AF2122/97           LRARIVAFQDRLADVVAAKDAELQRLAGKLTRD----
Rv3275c|M.tuberculosis_H37Rv        LRARIVAFQDRLADVVAAKDAELQRLAGKLTRD----
MMAR_1261|M.marinum_M               LRARIAAFQDQLAQTVQAKDAELQKLAGKLTRD----
MUL_2627|M.ulcerans_Agy99           LRARIAAFQDQLAQTVQAKDAELQKLAGKLTRD----
MLBr_00736|M.leprae_Br4923          LRAQLVAFQDRLADTVRAKDADLQRFRGKLIGD----
MAV_4244|M.avium_104                LRARIVEFQTQLADSVRAKDEALQRLHGKVTGQ----
                                    *: ::  :*  :   *  *:  *:    ::