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M. ulcerans Agy99 MUL_2464 (nuoF)

annotation: NADH dehydrogenase I (chain F) NuoF (NADH- ubiquinone oxidoreductase chain F)
coordinates: 2751428 - 2752774
length: 448

MTSQATPLTPVISRYWDDPESWTLATYRRHDGYRALEKALAMGPDAVIGTVKDSGLRGRGGAGFSTGTKW
SFIPQGDAGPAAKPHYLVVNADESEPGTCKDIPLMLATPHVLVEGVIIAAYAIRASHAFIYVRGEVLPVL
RRLQNAVAEAYAAGLLGRNINGSGFDLELVVHAGAGAYICGEETALLDSLEGRRGQPRLRPPFPAVAGLY
GCPTVINNVETIASVPSIILNGVDWFRSMGSEKSPGFTLYSLSGHVTRPGQYEAPLGITLRELLDYAGGI
RAGHQLKFWTPGGSSTPLLTDEHLDVPLDYEGVGGVGSMLGTKALEIFDETTCVVRAVRRWTEFYKHESC
GKCTPCREGTFWLDKIYARLETGKGTREDIDKLLDISDSILGKSFCALGDGAASPVMSSIKHFQNEYIAH
AEQGGCPFDPRDSMLTAGRNTAKGTGPQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_2464nuoF-100% (448)NADH dehydrogenase I (chain F) NuoF (NADH- ubiquinone oxidoreductase chain F)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3174nuoF0.091.14% (440) NADH dehydrogenase I chain F
M. gilvum PYR-GCKMflv_4486-0.083.80% (432) NADH-quinone oxidoreductase, F subunit
M. tuberculosis H37RvRv3150nuoF0.091.14% (440) NADH dehydrogenase I chain F
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2139-0.076.76% (426) NADH-quinone oxidoreductase, F subunit NuoF
M. marinum MMMAR_1478nuoF0.099.55% (448) NADH dehydrogenase I (chain F) NuoF (NADH- ubiquinone
M. avium 104MAV_4038nuoF0.092.84% (433) NADH-quinone oxidoreductase, F subunit
M. smegmatis MC2 155MSMEG_2058nuoF0.084.44% (437) NADH-quinone oxidoreductase, F subunit
M. thermoresistible (build 8)TH_0632nuoF0.080.59% (443) PROBABLE NADH DEHYDROGENASE I (CHAIN F) NUOF
M. vanbaalenii PYR-1Mvan_1880-0.083.87% (434) NADH-quinone oxidoreductase, F subunit

CLUSTAL 2.0.9 multiple sequence alignment


MUL_2464|M.ulcerans_Agy99           MTS-----------QATPLTPVISRYWDDPESWTLATYRRHDGYR---AL
MMAR_1478|M.marinum_M               MTS-----------QATPLTPVISRYWDDPESWTLATYRRHDGYR---AL
Mb3174|M.bovis_AF2122/97            MTT-----------QATPLTPVISRHWDDPESWTLATYQRHDRYRGYQAL
Rv3150|M.tuberculosis_H37Rv         MTT-----------QATPLTPVISRHWDDPESWTLATYQRHDRYRGYQAL
MAV_4038|M.avium_104                MTTTSETSEASGAPQATPLTPVISRFWDDPESWTLQTYHRHGGYA---AM
Mflv_4486|M.gilvum_PYR-GCK          ---------------MTSLTPVLSRFWDEPQPWTMDTYIRHGGYQ---AL
Mvan_1880|M.vanbaalenii_PYR-1       ---------------MTALTPVLSRFWDEPQPWSLDTYRRHGGYQ---AL
MSMEG_2058|M.smegmatis_MC2_155      ---------------MTPLTPVLSRFWDEPEPWTLETYRRHDGYQ---GL
TH_0632|M.thermoresistible__bu      ---------------MTPLTPVLTRFWDEPEPWSLDTYRRHDGYR---AL
MAB_2139|M.abscessus_ATCC_1997      -------------MTSSILSPVLSEHWDEPDAWTLDGYLRHGGYR---GL
                                                    : *:**::..**:*:.*::  * **. *    .:

MUL_2464|M.ulcerans_Agy99           EKALAMGPDAVIGTVKDSGLRGRGGAGFSTGTKWSFIPQ------GDA--
MMAR_1478|M.marinum_M               EKALAMGPDAVIGTVKDSGLRGRGGAGFSTGTKWSFIPQ------GDA--
Mb3174|M.bovis_AF2122/97            QKALTMPPDDVISIVKDSGLRGRGGAGFATGTKWSFIPQ------GDT--
Rv3150|M.tuberculosis_H37Rv         QKALTMPPDDVISIVKDSGLRGRGGAGFATGTKWSFIPQ------GDT--
MAV_4038|M.avium_104                KKALAMEPDAVIGMVKDSGLRGRGGAGFSTGTKWSFIPQ------GDT--
Mflv_4486|M.gilvum_PYR-GCK          ERALAMSPDDVIGTVKDSGLRGRGGAGFPTGTKWSFIPQ------GGE--
Mvan_1880|M.vanbaalenii_PYR-1       DRALAMTPDQVITTVKDSGLRGRGGAGFPTGTKWSFIPQ------GDE--
MSMEG_2058|M.smegmatis_MC2_155      QRALSMGPDDVIAFVKDSGLRGRGGAGFPTGTKWSFIPQER----GDQPA
TH_0632|M.thermoresistible__bu      EKALKMAPDEVIALVKESGLRGRGGAGFPTGTKWSFIPQAASTQAGAAGG
MAB_2139|M.abscessus_ATCC_1997      RTALGMDPDAVIALVKEAGLRGRGGAGFPTGAKWSFIPQ------GDG--
                                      ** * ** **  **::**********.**:*******      *    

MUL_2464|M.ulcerans_Agy99           -GPAAKPHYLVVNADESEPGTCKDIPLMLATPHVLVEGVIIAAYAIRASH
MMAR_1478|M.marinum_M               -GPAAKPHYLVVNADESEPGTCKDIPLMLATPHVLVEGVIIAAYAIRASH
Mb3174|M.bovis_AF2122/97            -GAAAKPHYLVVNADESEPGTCKDIPLMLATPHVLIEGVIIAAYAIRAHH
Rv3150|M.tuberculosis_H37Rv         -GAAAKPHYLVVNADESEPGTCKDIPLMLATPHVLIEGVIIAAYAIRAHH
MAV_4038|M.avium_104                -GAAAKPHYLVVNADESEPGTCKDIPLMLATPHVLIEGVIIAAYAIRANH
Mflv_4486|M.gilvum_PYR-GCK          -GAAAKPHYLVINADESEPGTCKDIPLMLTTPHFLVEGAIIAAYAIRANH
Mvan_1880|M.vanbaalenii_PYR-1       -GPAAKPHYLVINADESEPGTCKDIPLMLTTPHFLVEGAIIAAYAIRAHH
MSMEG_2058|M.smegmatis_MC2_155      GGPAAKPHYLVINADESEPGTCKDIPLLLTTPHFLVEGAIIAAYAIRARH
TH_0632|M.thermoresistible__bu      SDPAARPHYLVVNADESEPGTCKDIPLMLTTPHFLVEGAIIAAYAIRARH
MAB_2139|M.abscessus_ATCC_1997      -----KPHYLVVNADESEPGTCKDIPLMLATPHTLIEGIVIAAFAIRASQ
                                         :*****:***************:*:*** *:** :***:**** :

MUL_2464|M.ulcerans_Agy99           AFIYVRGEVLPVLRRLQNAVAEAYAAGLLGRNINGSGFDLELVVHAGAGA
MMAR_1478|M.marinum_M               AFIYVRGEVLPVLRRLQNAVAEAYAAGLLGRNINGSGFDLELVVHAGAGA
Mb3174|M.bovis_AF2122/97            AFVYVRGEVVPVLRRLHNAVAEAYAAGFLGRNIGGSGFDLELVVHAGAGA
Rv3150|M.tuberculosis_H37Rv         AFVYVRGEVVPVLRRLHNAVAEAYAAGFLGRNIGGSGFDLELVVHAGAGA
MAV_4038|M.avium_104                AFIYVRGEVLPVLRRLQNAVAEAYAAGYLGRDIDGSGFDLELVVHAGAGA
Mflv_4486|M.gilvum_PYR-GCK          AFIYLRGEVVPVLRRLQAAVAEAYAAGHLGHDIHGSGFDLELTVHAGAGA
Mvan_1880|M.vanbaalenii_PYR-1       AFIYLRGEVVPVLRRLQAAVAEAYAAGHLGSDIHGSGFDLELIVHAGAGA
MSMEG_2058|M.smegmatis_MC2_155      AFIYVRGEVLPVLRRLQAAVAEAYAAGYLGTDIMGSGFDLDLIVHAGAGA
TH_0632|M.thermoresistible__bu      AFIYLRGEVVPVLRRLQQAVAEAYEAGYLGADIRGSGFDLDLIVHAGAGA
MAB_2139|M.abscessus_ATCC_1997      AFIYVRGEVISVIRRLHAAVAQAYKAGYLGRNILDSGFDLELVVHAGAGA
                                    **:*:****:.*:***: ***:** ** ** :* .*****:* *******

MUL_2464|M.ulcerans_Agy99           YICGEETALLDSLEGRRGQPRLRPPFPAVAGLYGCPTVINNVETIASVPS
MMAR_1478|M.marinum_M               YICGEETALLDSLEGRRGQPRLRPPFPAVAGLYGCPTVINNVETIASVPS
Mb3174|M.bovis_AF2122/97            YICGEETALLDSLEGRRGQPRLRPPFPAVAGLYGCPTVINNVETIASVPS
Rv3150|M.tuberculosis_H37Rv         YICGEETALLDSLEGRRGQPRLRPPFPAVAGLYGCPTVINNVETIASVPS
MAV_4038|M.avium_104                YICGEETALLDSLEGRRGQPRLRPPFPAVAGLYGCPTVINNVETIASVPS
Mflv_4486|M.gilvum_PYR-GCK          YICGEETALLDSLEGRRGQPRLRPPFPAVAGLYACPTVVNNVESIASVPP
Mvan_1880|M.vanbaalenii_PYR-1       YICGEETALLDSLEGRRGQPRLRPPFPAVAGLYACPTVVNNVESIASVPP
MSMEG_2058|M.smegmatis_MC2_155      YICGEETALLDSLEGRRGQPRLRPPFPAVAGLYACPTVVNNVESIASVPP
TH_0632|M.thermoresistible__bu      YICGEETALLDSLEGRRGQPRLRPPFPAVAGLYACPTVVNNVESIASVPP
MAB_2139|M.abscessus_ATCC_1997      YICGEETALLDSLEGRRGQPRLRPPFPAVAGLYASPTVVNNVESIASVPV
                                    *********************************..***:****:***** 

MUL_2464|M.ulcerans_Agy99           IILNGVDWFRSMGSEKSPGFTLYSLSGHVTRPGQYEAPLGITLRELLDYA
MMAR_1478|M.marinum_M               IILNGVDWFRSMGSEKSPGFTLYSLSGHVTRPGQYEAPLGITLRELLDYA
Mb3174|M.bovis_AF2122/97            IILGGIDWFRSMGSEKSPGFTLYSLSGHVTRPGQYEAPLGITLRELLDYA
Rv3150|M.tuberculosis_H37Rv         IILGGIDWFRSMGSEKSPGFTLYSLSGHVTRPGQYEAPLGITLRELLDYA
MAV_4038|M.avium_104                IIGNGVDWFRSMGSEKSPGFTLYSLSGHVTRPGQYEAPLGITLRELLDYA
Mflv_4486|M.gilvum_PYR-GCK          ILLNGVDWFRSMGSEKSPGFTLYSLSGHVTTPGQYEAPLGITLRELLDYA
Mvan_1880|M.vanbaalenii_PYR-1       VLLNGVDWFRSMGSEKSPGFTLYSLSGHVTTPGQYEAPLGITLRELLEYA
MSMEG_2058|M.smegmatis_MC2_155      IMVNGVDWFRSMGSEKSPGFTLYSLSGHVTRPGQYEAPLGITLRELLEYA
TH_0632|M.thermoresistible__bu      IVLNGIDWFRSMGSEKSPGFTLYSLSGHVTRPGQYEAPLGITLRELLDYA
MAB_2139|M.abscessus_ATCC_1997      ILRRGAEWFRTMGTEKSPGFTLYSLSGHVRTPGQYEAPLGVTLRQLLELA
                                    ::  * :***:**:***************  *********:***:**: *

MUL_2464|M.ulcerans_Agy99           GGIRAGHQLKFWTPGGSSTPLLTDEHLDVPLDYEGVGGVGSMLGTKALEI
MMAR_1478|M.marinum_M               GGIRAGHQLKFWTPGGSSTPLLTDEHLDVPLDYEGVGGVGSMLGTKALEI
Mb3174|M.bovis_AF2122/97            GGVRAGHRLKFWTPGGSSTPLLTDEHLDVPLDYEGVGAAGSMLGTKALEI
Rv3150|M.tuberculosis_H37Rv         GGVRAGHRLKFWTPGGSSTPLLTDEHLDVPLDYEGVGAAGSMLGTKALEI
MAV_4038|M.avium_104                GGVRAGHRLKFWTPGGSSTPLLTDEHLDVPLDYEGVGGVGSMLGTKALEI
Mflv_4486|M.gilvum_PYR-GCK          GGVRAGHELKFWTPGGSSTPLLTADHLDVPLDYEGMAGVGSMLGTKALQI
Mvan_1880|M.vanbaalenii_PYR-1       GGVRAGHELKFWTPGGSSTPLLTAEHLDVPLDYEGMAGVGSMLGTKALQI
MSMEG_2058|M.smegmatis_MC2_155      GGVRAGHQLKFWTPGGSSTPLLTAEHLDVPLDYEGMASVGSMLGTKALQI
TH_0632|M.thermoresistible__bu      GGVRAGRSLKFWTPGGSSTPLLTAEHLDVPLDYEGIAGVGSMLGTKALQI
MAB_2139|M.abscessus_ATCC_1997      GGVRDGRALKFWTPGGSSTPLFTAEQLDVPLDYEGVSAAGSMLGTKALQI
                                    **:* *: *************:* ::*********:...*********:*

MUL_2464|M.ulcerans_Agy99           FDETTCVVRAVRRWTEFYKHESCGKCTPCREGTFWLDKIYARLETGKGTR
MMAR_1478|M.marinum_M               FDETTCVVRAVRRWTEFYKHESCGKCTPCREGTFWLDKIYARLETGKGTR
Mb3174|M.bovis_AF2122/97            FDETTCVVRAVRRWTEFYKHESCGKCTPCREGTFWLDKIYERLETGRGSH
Rv3150|M.tuberculosis_H37Rv         FDETTCVVRAVRRWTEFYKHESCGKCTPCREGTFWLDKIYERLETGRGSH
MAV_4038|M.avium_104                FDETTCVVRAVRRWTYFYKHESCGKCTPCREGTFWLDQIYERLETGKGTA
Mflv_4486|M.gilvum_PYR-GCK          FDDTTCVVRAVRRWTQFYAHESCGKCTPCREGTYWLAQIYERLETGRGTE
Mvan_1880|M.vanbaalenii_PYR-1       FDETTCVVRAVRRWTQFYAHESCGKCTPCREGTYWLAQIYERLETGAGTE
MSMEG_2058|M.smegmatis_MC2_155      FDETTCVVRAVRRWTQFYAHESCGKCTPCREGTYWLAQIYARLENGAGTE
TH_0632|M.thermoresistible__bu      FDDTTCVVRAVARWTDFYAHESCGKCTPCREGTYWLKQIYARLESGAGTR
MAB_2139|M.abscessus_ATCC_1997      FDDTTCVVRAVLRWTEFYAHESCGKCTPCREGTYWLVRILQRLESGEGKA
                                    **:******** *** ** **************:** :*  ***.* *. 

MUL_2464|M.ulcerans_Agy99           EDIDKLLDISDSILGKSFCALGDGAASPVMSSIKHFQNEYIAHAE--QGG
MMAR_1478|M.marinum_M               EDIDKLLDISDSILGKSFCALGDGAASPVMSSIKHFQDEYIAHVE--QGG
Mb3174|M.bovis_AF2122/97            EDIDKLLDISDSILGKSFCALGDGAASPVMSSIKHFRDEYLAHVE--GGG
Rv3150|M.tuberculosis_H37Rv         EDIDKLLDISDSILGKSFCALGDGAASPVMSSIKHFRDEYLAHVE--GGG
MAV_4038|M.avium_104                EDIDKLLDISDTILGKSFCALGDGAASPVMSSIKYFRDEYVAHVE--NGR
Mflv_4486|M.gilvum_PYR-GCK          ADLDKLLDISDNIFGKSFCALGDGAASPIMSSLKHFRDEYEAHLG---NA
Mvan_1880|M.vanbaalenii_PYR-1       ADLDKLLDISDNIFGKSFCALGDGAASPIMSSLKHFRAEYEAHLDPVGKG
MSMEG_2058|M.smegmatis_MC2_155      ADIDKLLDISDNIFGKSFCALGDGAASPIMSSIKHFRDEYVAHLD---GG
TH_0632|M.thermoresistible__bu      ADLDKLLDISDIVLGKSFCALGDGAAMPIQSSLRYFRDEYEAHLDPASPG
MAB_2139|M.abscessus_ATCC_1997      EDLDKLLDISDIVLGKSFCALGDGAASPIMSSLKYFRTEYEAHLD---NG
                                     *:******** ::************ *: **:::*: ** **       

MUL_2464|M.ulcerans_Agy99           CPFDPRDSMLTAGRNTAKGTGPQ
MMAR_1478|M.marinum_M               CPFDPRDSMLTAGRNTAKGTGPQ
Mb3174|M.bovis_AF2122/97            CPFDPRDSMLVANGVDA------
Rv3150|M.tuberculosis_H37Rv         CPFDPRDSMLVANGVDA------
MAV_4038|M.avium_104                CPFDPRDSMLTPNGSDS------
Mflv_4486|M.gilvum_PYR-GCK          CPFDPYASMLAAPEGVGV-----
Mvan_1880|M.vanbaalenii_PYR-1       CPFDPYASMLAAPEGVGA-----
MSMEG_2058|M.smegmatis_MC2_155      CPFDPHASTLMATEGAGV-----
TH_0632|M.thermoresistible__bu      CPFDPHASTLMATEEVRA-----
MAB_2139|M.abscessus_ATCC_1997      CPFDPAASTVFGEVSA-------
                                    *****  * :