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M. ulcerans Agy99 MUL_2453 (-)

annotation: two-component system response regulator
coordinates: 2740986 - 2741387
length: 133

VADSSEDLRILVYSDNVQTREQVVRALGKRLHPDLPALTYVEVATGPMVLRRMDEGGIDLAILDGEATPT
GGMGIAKQLKDELDNCPPLVVLTGRPDDAWLASWSRAEAAVPHPIDPIVLGRTVLGLLRAPAL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_2453--100% (133)two-component system response regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3167-2e-6487.88% (132) response regulator
M. gilvum PYR-GCKMflv_4480-3e-5476.34% (131) response regulator receiver protein
M. tuberculosis H37RvRv3143-2e-6487.88% (132) response regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2133-2e-3960.47% (129) response regulator
M. marinum MMMAR_1486-4e-73100.00% (133) two-component system response regulator
M. avium 104MAV_4032-8e-6185.94% (128) two-component system response regulator
M. smegmatis MC2 155MSMEG_2064-3e-5273.44% (128) two-component system response regulator
M. thermoresistible (build 8)TH_0638-6e-4670.87% (127) PROBABLE RESPONSE REGULATOR
M. vanbaalenii PYR-1Mvan_1886-7e-5374.42% (129) response regulator receiver protein

CLUSTAL 2.0.9 multiple sequence alignment


MUL_2453|M.ulcerans_Agy99           ----------------MADS---SEDLRILVYSDNVQTREQVVRALGKRL
MMAR_1486|M.marinum_M               MVPPGAGQPETSSICTVADS---SEDLRILVYSDNVQTREQVVRALGKRL
Mb3167|M.bovis_AF2122/97            ----------------MPDS---STALRILVYSDNVQTRERVMRALGKRL
Rv3143|M.tuberculosis_H37Rv         ----------------MPDS---STALRILVYSDNVQTRERVMRALGKRL
MAV_4032|M.avium_104                ------------MSDSTPQS---SVALRILVYSSNAQTRERVMRALGRHL
Mflv_4480|M.gilvum_PYR-GCK          ------------MVVPSAET---RGVLRVLVYSDNPRTREQVRLALGRRI
Mvan_1886|M.vanbaalenii_PYR-1       ------------MAAPSSESSRAQDPLRILVYSDNPRTREQVRLALGRRI
MSMEG_2064|M.smegmatis_MC2_155      ------------MAG--------SAPLRILVYSDNPRTREQVRLALGKRI
TH_0638|M.thermoresistible__bu      ------------VSRPVDD----AAALRILVYSDDPRTRDAVRTALGTRL
MAB_2133|M.abscessus_ATCC_1997      ------------------------MALQVLVYSDDITVRRKVIQGIGARP
                                                              *::****.:  .*  *  .:* : 

MUL_2453|M.ulcerans_Agy99           HPDLPALTYVEVATGPMVLRRMDEG----GIDLAILDGEATPTGGMGIAK
MMAR_1486|M.marinum_M               HPDLPALTYVEVATGPMVLRRMDEG----GIDLAILDGEATPTGGMGIAK
Mb3167|M.bovis_AF2122/97            HPDLPDLTYVEVATGPMVIRQMDRG----GIDLAILDGEATPTGGMGIAK
Rv3143|M.tuberculosis_H37Rv         HPDLPDLTYVEVATGPMVIRQMDRG----GIDLAILDGEATPTGGMGIAK
MAV_4032|M.avium_104                HPDLPELSYVEVATGPMVVKTMDQG----GIDLAILDGEATPTGGMGIAK
Mflv_4480|M.gilvum_PYR-GCK          HPELPELDYVEVATGPMVVRQMDAG----GFDLAILDGEATPVGGMGIAK
Mvan_1886|M.vanbaalenii_PYR-1       HPELPELSYLEVATGPMVIRQMDEG----GFDLAILDGEAAPVGGMGIAK
MSMEG_2064|M.smegmatis_MC2_155      HPELPEIEYVDVATAPMAISQMDAG----GFDLAILDGEATPAGGMGVAK
TH_0638|M.thermoresistible__bu      HPDLPELGYQEVATEPMVHEHLRSG----HFDLVILDGEATPAGGMGIAK
MAB_2133|M.abscessus_ATCC_1997      DSALPPLEFVEVATGPMVIERLAAPGSLPGIDLAILDGEATPFGGMGVAK
                                    .. ** : : :*** **.   :        :**.******:* ****:**

MUL_2453|M.ulcerans_Agy99           QLKDELDNCPPLVVLTGRPDDAWLASWSRAEAAVPHPIDPIVLGRTVLGL
MMAR_1486|M.marinum_M               QLKDELDNCPPLVVLTGRPDDAWLASWSRAEAAVPHPIDPIVLGRTVLGL
Mb3167|M.bovis_AF2122/97            QLKDELASCPPILVLTGRPDDTWLASWSRAEAAVPHPVDPIVLGRTVLSL
Rv3143|M.tuberculosis_H37Rv         QLKDELASCPPILVLTGRPDDTWLASWSRAEAAVPHPVDPIVLGRTVLSL
MAV_4032|M.avium_104                QLKDELDACPPLVVLTGRPDDAWLASWSRAEAAVPHPIDPILLGRTVLNL
Mflv_4480|M.gilvum_PYR-GCK          QLKDELDVCPPILVLTGRPDDAWLARWSRAEAAVPHPIDPIRLGDAVVSL
Mvan_1886|M.vanbaalenii_PYR-1       QLKDEIDDCPPVLVLTRRADDAWLARWSRAEAAVPHPIDPIRLGDAVVSL
MSMEG_2064|M.smegmatis_MC2_155      QVKDEIDDCPPILVLTGRADDAWLAKWSRAEAAVPHPIDPIRLSDAVVSL
TH_0638|M.thermoresistible__bu      QLKDELADCPPVLVLTGRRDDAWLARWSRAEAAVPQPIDPIELGDAVLSL
MAB_2133|M.abscessus_ATCC_1997      QVKDEVDAPPPIVILTGRPQDNWLASWSRAEAVVPRPIDPMRLTATVIDL
                                    *:***:   **:::** * :* *** ******.**:*:**: *  :*:.*

MUL_2453|M.ulcerans_Agy99           LRAPAL---
MMAR_1486|M.marinum_M               LRAPAL---
Mb3167|M.bovis_AF2122/97            LRAPAH---
Rv3143|M.tuberculosis_H37Rv         LRAPAH---
MAV_4032|M.avium_104                LRTPVR---
Mflv_4480|M.gilvum_PYR-GCK          LRPAA----
Mvan_1886|M.vanbaalenii_PYR-1       LRPSA----
MSMEG_2064|M.smegmatis_MC2_155      LRAPAQ---
TH_0638|M.thermoresistible__bu      LRTRTS---
MAB_2133|M.abscessus_ATCC_1997      LGSAAASRR
                                    * . .