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PAGPRGGGCTEIVTVLKRAWLPLVLAVVFAVGGFAVSRVRGMFGSQQLPTYADSTPAGSVSSSGPKRVRY EIFGAPGTIADINYMDPAGEAQQLNDVALPWSIEVETDAPSMVANIIAQANTDFLGCRISSGGEVKDERT SSAVSAYVYCIAKSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2383 | mmpS4 | - | 100% (156) | membrane protein MmpS4 |
| M. ulcerans Agy99 | MUL_2293 | mmpS4_1 | 8e-31 | 38.89% (144) | membrane transporter |
| M. ulcerans Agy99 | MUL_0758 | mmpS5 | 2e-28 | 42.36% (144) | transmembrane proteinm, MmpS5 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0459c | mmpS4 | 1e-37 | 48.94% (141) | membrane protein |
| M. gilvum PYR-GCK | Mflv_2704 | - | 6e-43 | 58.27% (139) | membrane family protein |
| M. tuberculosis H37Rv | Rv0451c | mmpS4 | 1e-37 | 48.94% (141) | membrane protein |
| M. leprae Br4923 | MLBr_02377 | - | 5e-36 | 47.02% (151) | hypothetical protein MLBr_02377 |
| M. abscessus ATCC 19977 | MAB_2300 | - | 3e-39 | 58.96% (134) | putative membrane protein, MmpS |
| M. marinum M | MMAR_3175 | mmpS4 | 4e-69 | 96.97% (132) | membrane protein MmpS4 |
| M. avium 104 | MAV_3247 | - | 9e-36 | 48.53% (136) | MmpS4 protein |
| M. smegmatis MC2 155 | MSMEG_0226 | - | 2e-32 | 46.81% (141) | MmpS5 protein |
| M. thermoresistible (build 8) | TH_2866 | - | 3e-50 | 62.50% (144) | PUTATIVE hypothetical protein Mvan_3834 |
| M. vanbaalenii PYR-1 | Mvan_3834 | - | 6e-45 | 61.59% (138) | hypothetical protein Mvan_3834 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2383|M.ulcerans_Agy99 MPAGPRGGGCTEIVTVLKRAWLPLVLAVVFAVGGFAVSRVRGMFGSQQLP
MMAR_3175|M.marinum_M ------------------------MLAVVFAVGGFAVSRVRGMFGSQQLP
Mflv_2704|M.gilvum_PYR-GCK ----------------MSRAWIPLVLVIVLLVAGFTVWRLRNMFASHPLP
Mvan_3834|M.vanbaalenii_PYR-1 ----------------MTRAWIPLVLVLVLVVGGLAVWRIRNIFGSHQLP
TH_2866|M.thermoresistible__bu --LWTSKAKDSAILTRLARAWIPLVMVVVVAIGGFAVWRIRGIFGSEQLP
MAB_2300|M.abscessus_ATCC_1997 -----------------------MVMVLVLVIAGFAVWRIRGIFGSHQLP
Mb0459c|M.bovis_AF2122/97 ---------------MLMRTWIPLVILVVVIVGGFTVHRIRGFFGSENRP
Rv0451c|M.tuberculosis_H37Rv ---------------MLMRTWIPLVILVVVIVGGFTVHRIRGFFGSENRP
MLBr_02377|M.leprae_Br4923 -MSKRQRGKGISIFKLLSRIWIPLVILVVLVVGGFVVYRVHSYFASEKRE
MAV_3247|M.avium_104 ----------------MKRLWIPLVIVAVVVAGGLTVSRLHGIFGSEKRP
MSMEG_0226|M.smegmatis_MC2_155 -------------MKLLKRFWIPLLIGVVVLVGAFTVMRVRTFFGSGDDP
:: *. ..:.* *:: *.*
MUL_2383|M.ulcerans_Agy99 TYADSTPAGSVSSSGPKRVRYEIFGAPGTIADINYMDPAGEAQQLNDVAL
MMAR_3175|M.marinum_M TYADSTPAGNVSSSGPKRVRYEIFGAPGTIADINYMDPAGEAQQLNDVAL
Mflv_2704|M.gilvum_PYR-GCK TYAGSMSA-DTNKSDPKIVRYEIFGVPGATADINYIDDEGDANQIIGAPL
Mvan_3834|M.vanbaalenii_PYR-1 TYAGSMSE-DSNKSDPKIVRYEIFGDPGATADINYIDDEGDPNQIVGATL
TH_2866|M.thermoresistible__bu TYAGSTSV-DTDKANPKRVRYEIFGAPGTVADINYIDAEGDPHQVNGATL
MAB_2300|M.abscessus_ATCC_1997 TYAGSMTD-DKNNSKPKHVLYEIFGPPGTIADINYIDKEGEPHQINGAVL
Mb0459c|M.bovis_AF2122/97 SYSDTNLE-NSKPFNPKHLTYEIFGPPGTVADISYFDVNSEPQRVDGAVL
Rv0451c|M.tuberculosis_H37Rv SYSDTNLE-NSKPFNPKHLTYEIFGPPGTVADISYFDVNSEPQRVDGAVL
MLBr_02377|M.leprae_Br4923 SYADSNLG-SSKPFNPKQIVYEVFGPPGTVADISYFDANSDPQRIDGAQL
MAV_3247|M.avium_104 SYADTRQQ-DTKPFNPKHVKYEVFGPAGAMADISYFDANGEPQHINGVEL
MSMEG_0226|M.smegmatis_MC2_155 SLASAKVD-DTKPFDPKVVIYEIYGEPGATADVNYLDLDAQPQRVDGVSL
: :.: . . ** : **::* .*: **:.*:* .:.::: .. *
MUL_2383|M.ulcerans_Agy99 PWSIEVETDAPSMVANIIAQA-NTDFLGCRISSGGEVKDERTSSAVSAYV
MMAR_3175|M.marinum_M PWSIEVETDAPSMVANIIAQG-NSDFLGCRISSDGEVKDERTSSAVSAYV
Mflv_2704|M.gilvum_PYR-GCK PWAIEVETDSPAMVGNIVAQG-DGDFIGCRILSDGELKDERTIHNYTAYI
Mvan_3834|M.vanbaalenii_PYR-1 PWSIEVETNSPAMVGNVVAQG-DSDFIGCRISADGVVKDERTAHNVSAYV
TH_2866|M.thermoresistible__bu PWSIEIVTNSPAMAGNVLAQG-DSDFIGCRIVSDGVVKDERTTQRVSAYV
MAB_2300|M.abscessus_ATCC_1997 PWSIEIITTAPSMTGNILAQTRNADGLGCRITANDEKKDERYTNEVSAYV
Mb0459c|M.bovis_AF2122/97 PWSLHITTNDAAVMGNIVAQG-NSDSIGCRITVDGKVRAERVSNEVNAYT
Rv0451c|M.tuberculosis_H37Rv PWSLHITTNDAAVMGNIVAQG-NSDSIGCRITVDGKVRAERVSNEVNAYT
MLBr_02377|M.leprae_Br4923 PWSLLMTTTLAAVMGNLVAQG-NTDSIGCRIIVDGVVKAERVSNEVNAYT
MAV_3247|M.avium_104 PWTFDISTTLPSIVGNVVAQG-NSDSLGCRILVDGVVKTERISHELNAFT
MSMEG_0226|M.smegmatis_MC2_155 PWTLTLSTTAPSVFPNIVAQG-NGDSITCRITVDDELKDERTSNGVNAQT
**:: : * .:: *::** : * : *** .. : ** .*
MUL_2383|M.ulcerans_Agy99 YCIAKSA
MMAR_3175|M.marinum_M YCIAKSA
Mflv_2704|M.gilvum_PYR-GCK YCFSKAT
Mvan_3834|M.vanbaalenii_PYR-1 YCFTKSA
TH_2866|M.thermoresistible__bu YCFTKSA
MAB_2300|M.abscessus_ATCC_1997 YCFVKSA
Mb0459c|M.bovis_AF2122/97 YCLVKSA
Rv0451c|M.tuberculosis_H37Rv YCLVKSA
MLBr_02377|M.leprae_Br4923 YCLVKSA
MAV_3247|M.avium_104 YCVLTAT
MSMEG_0226|M.smegmatis_MC2_155 FCLVKSA
:*. .::