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M. ulcerans Agy99 MUL_1754 (alaS)

annotation: alanyl-tRNA synthetase
coordinates: 1940382 - 1943087
length: 901

VQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLGQRTPPYATATSIQKCIRTPD
IDEVGITTRHNTFFQMAGNFSFGDYFKRGAIELAWALLTNSVADGGYGLDPEKLWATVYLDDDEAAGLWR
EVAGLPADRIQRRGMADNYWSMGIPGPCGPSSEIYYDRGPDYGPEGGPVVNEDRYLEIWNLVFMQNERGE
GTTKEDYEILGPLPRKNIDTGMGVERVALILQGVPNVYETDLLRPIIDLVAARAPRGYDQGNHADDVRYR
IIADHSRTAAILIADGVSPGNDGRGYVLRRLLRRVIRSAKLLNIDTAIVGDLMATVRDAMGPSYPELASD
SDRINRIAVAEETAFNRTLASGSRLFDEVAGATRSSGVSVVSGSDAFTLHDTYGFPIELTLEMASEAGLT
VDEGGFRELMAQQRRRAKADAAARKHAHADLTAYRELVDAGPTEFTGFDELTSEARILGIFVDGKRVPVV
AHGQAVDADRVELVLDRTPLYAESGGQIADVGTISGTGSGSSARAAVTDVQKIAKTLWLHRVNVESGEFV
EGDGVVAAADAGWRKGATQGHSGTHMVHAALRQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTEEQRGQIE
EVTNQAVQADFAVHTFTEQLEKAKAMGAMALFGECYPDEVRVVEIGGPFSIELCGGTHVATSAQIGPVTI
LGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKVPSEEVPARVASLVERLKAAEKELERARLA
SVRAAAVNAAAGAERIGNVRLVAQRMSSEMTPADLRTLVGDIRGKLGSDPAVVALIAAPAGGESSTVPYV
VAANQAAQGLGLGANELIKHLAAAVDGRGGGKADLAQGSGKKPAGIAAALEALRAEIARVG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1754alaS-100% (901)alanyl-tRNA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2585calaS0.086.11% (907) alanyl-tRNA synthetase
M. gilvum PYR-GCKMflv_3763alaS0.081.00% (900) alanyl-tRNA synthetase
M. tuberculosis H37RvRv2555calaS0.086.22% (907) alanyl-tRNA synthetase
M. leprae Br4923MLBr_00512alaS0.084.47% (908) alanyl-tRNA synthetase
M. abscessus ATCC 19977MAB_2851calaS0.077.64% (899) alanyl-tRNA synthetase
M. marinum MMMAR_2170alaS0.099.22% (901) alanyl-tRNA synthetase AlaS
M. avium 104MAV_3431alaS0.086.33% (900) alanyl-tRNA synthetase
M. smegmatis MC2 155MSMEG_3025alaS0.083.54% (899) alanyl-tRNA synthetase
M. thermoresistible (build 8)TH_0114alaS0.080.75% (904) PROBABLE ALANYL-TRNA SYNTHETASE ALAS (ALANINE--TRNA LIGASE)
M. vanbaalenii PYR-1Mvan_2640alaS0.082.56% (900) alanyl-tRNA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3763|M.gilvum_PYR-GCK          MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLG
Mvan_2640|M.vanbaalenii_PYR-1       MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLG
MSMEG_3025|M.smegmatis_MC2_155      MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLG
Mb2585c|M.bovis_AF2122/97           MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
Rv2555c|M.tuberculosis_H37Rv        MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
MAV_3431|M.avium_104                MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLG
MUL_1754|M.ulcerans_Agy99           MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
MMAR_2170|M.marinum_M               MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
MLBr_00512|M.leprae_Br4923          MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
TH_0114|M.thermoresistible__bu      VQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLG
MAB_2851c|M.abscessus_ATCC_199      MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
                                    :*********************************************:***

Mflv_3763|M.gilvum_PYR-GCK          QRTPPWDRATSVQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKKGA
Mvan_2640|M.vanbaalenii_PYR-1       QRTPPWDRAASVQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKKGA
MSMEG_3025|M.smegmatis_MC2_155      QRTPPWNRATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
Mb2585c|M.bovis_AF2122/97           QRTPPYPTATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
Rv2555c|M.tuberculosis_H37Rv        QRTPPYPTATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
MAV_3431|M.avium_104                ARTPPYPTATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKREA
MUL_1754|M.ulcerans_Agy99           QRTPPYATATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
MMAR_2170|M.marinum_M               QRTPPYATATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
MLBr_00512|M.leprae_Br4923          QCTPPYATATSIQKCIRTPDIDDVGITTRHNTFFQMAGNFSFGDYFKRGA
TH_0114|M.thermoresistible__bu      QRTPPYTRATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
MAB_2851c|M.abscessus_ATCC_199      QRTPPYNTATSVQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKREA
                                      ***:  *:*:**********:************************: *

Mflv_3763|M.gilvum_PYR-GCK          IELAWSLLTNPVSEGGYGFDPERLWATVYLDDDEAIELWQEVAGLPAERI
Mvan_2640|M.vanbaalenii_PYR-1       IEFAWTLLTNPVEAGGYGFDPERLWATVYLDDDEAIGYWQEVAGLPLERI
MSMEG_3025|M.smegmatis_MC2_155      IELAWTLLTNPVEEGGYGFDPERLWATVYLDDDEAIGLWQEVAGLPAERI
Mb2585c|M.bovis_AF2122/97           IELAWALLTNSLAAGGYGLDPERIWTTVYFDDDEAVRLWQEVAGLPAERI
Rv2555c|M.tuberculosis_H37Rv        IELAWALLTNSLAAGGYGLDPERIWTTVYFDDDEAVRLWQEVAGLPAERI
MAV_3431|M.avium_104                IELAWTLLTGSVEQGGYGLDPERIWTTVYFDDDEAVRLWQEIAGLPAERI
MUL_1754|M.ulcerans_Agy99           IELAWALLTNSVADGGYGLDPEKLWATVYLDDDEAAGLWREVAGLPADRI
MMAR_2170|M.marinum_M               IELAWALLTNSVADGGYGLDPEKLWATVYLDDDEAAGLWREVAGLPADRI
MLBr_00512|M.leprae_Br4923          IELAWALLTNSFADGGYGLDPERLWATVYLDDDEAAGLWQEIAGLPPERI
TH_0114|M.thermoresistible__bu      IEYAWSLLTKSVDDGGYGFDPEKIWATVYLDDDEAADLWQEIAGLPPERI
MAB_2851c|M.abscessus_ATCC_199      IRLAWTLLTNPVSEGGYGFDPEKLWATVYLDDDEAIGLWQEVAGLPLDRI
                                    *. **:*** ..  ****:***::*:***:*****   *:*:**** :**

Mflv_3763|M.gilvum_PYR-GCK          QRRGMADNYWSMGIPGPCGPCSEIYYDRGPDYGIDGGPEANEDRYIEIWN
Mvan_2640|M.vanbaalenii_PYR-1       QRRGMADNYWSMGIPGPCGPSSEIYYDRGPEYGIEGGPEANEDRYIEIWN
MSMEG_3025|M.smegmatis_MC2_155      QRRGMADNYWSMGIPGPCGPSSEIYYDRGPEYGVEGGPEANEDRYIEIWN
Mb2585c|M.bovis_AF2122/97           QRRGMADNYWSMGIPGPCGPSSEIYYDRGPEFGPAGGPIVSEDRYLEVWN
Rv2555c|M.tuberculosis_H37Rv        QRRGMADNYWSMGIPGPCGPSSEIYYDRGPEFGPAGGPIVSEDRYLEVWN
MAV_3431|M.avium_104                QRRGMEDNYWSMGIPGPCGPSSEIYYDRGEEFGVGGGPIANEDRYVELWN
MUL_1754|M.ulcerans_Agy99           QRRGMADNYWSMGIPGPCGPSSEIYYDRGPDYGPEGGPVVNEDRYLEIWN
MMAR_2170|M.marinum_M               QRRGMADNYWSMGIPGPCGPSSEIYYDRGPDYGPEGGPVVNEDRYLEIWN
MLBr_00512|M.leprae_Br4923          QRRGMADNYWSMGIPGPCGPSSEIYYDRGPEFGPEGGPIVNEDRYLEVWN
TH_0114|M.thermoresistible__bu      QRRGMADNYWSMGIPGPCGPSSEIYYDRGPDYGVEGGPIANEDRYIEIWN
MAB_2851c|M.abscessus_ATCC_199      QRRGMADNYWSMGIPGPCGPCSEIYYDRGPEYGIEGGPEANEDRYIEIWN
                                    ***** **************.******** ::*  *** ..****:*:**

Mflv_3763|M.gilvum_PYR-GCK          LVFMQNERGEGTSKDDFEILGPLPRKNIDTGMGVERIACLLQGVDNVYET
Mvan_2640|M.vanbaalenii_PYR-1       LVFMQNERGEGTSKEDFEILGPLPRKNIDTGMGVERVACLLQGVDNVYET
MSMEG_3025|M.smegmatis_MC2_155      LVFMQNERGEGTSKEDFEILGPLPRKNIDTGMGIERVACLLQGVDNVYET
Mb2585c|M.bovis_AF2122/97           LVFMQNERGEGTTKEDYQILGPLPRNNIDTGMGVERIALVLQDVHNVYET
Rv2555c|M.tuberculosis_H37Rv        LVFMQNERGEGTTKEDYQILGPLPRKNIDTGMGVERIALVLQDVHNVYET
MAV_3431|M.avium_104                LVFMQSERGEGTSKTDFEILGPLPRKNIDTGMGVERVAFVLQGVHNVYET
MUL_1754|M.ulcerans_Agy99           LVFMQNERGEGTTKEDYEILGPLPRKNIDTGMGVERVALILQGVPNVYET
MMAR_2170|M.marinum_M               LVFMQNERGEGTTKEDYEILGPLPRKNIDTGMGVERVALILQGVPNVYET
MLBr_00512|M.leprae_Br4923          LVFMQNERGEGTTKEDYEIRGPLPRKNIDTGMGVERIALVLQGVHNVYEI
TH_0114|M.thermoresistible__bu      LVFMENERGAGPAKEGYEILGPLPRKNIDTGMGIERVACLLQGVDNVYET
MAB_2851c|M.abscessus_ATCC_199      LVFMQNERGEGTSKTDFEILGPLPRQNIDTGMGVERIACLLQGVDNVYET
                                    ****:.*** *.:* .::* *****:*******:**:* :**.* **** 

Mflv_3763|M.gilvum_PYR-GCK          DLVRPVIDLVAGIAPRGYG----QGNHTDDVRYRIIGDHSRTAAIIIGDG
Mvan_2640|M.vanbaalenii_PYR-1       DLLRPAIDLVAGIAPRGYG----QGVHEDDVRYRIIADHSRTAAIIIGDG
MSMEG_3025|M.smegmatis_MC2_155      DLLRPVIDKVAAVAPRGYG----AGNHDDDVRYRIIADHTRTAAIIIADG
Mb2585c|M.bovis_AF2122/97           DLLRPVIDTVARVAARAYD----VGNHEDDVRYRIIADHSRTAAILIGDG
Rv2555c|M.tuberculosis_H37Rv        DLLRPVIDTVARVAARAYD----VGNHEDDVRYRIIADHSRTAAILIGDG
MAV_3431|M.avium_104                DLLRPVIDAVAARAPRPYD----AGNHDDDVRYRIIADHSRTAAILIGDG
MUL_1754|M.ulcerans_Agy99           DLLRPIIDLVAARAPRGYD----QGNHADDVRYRIIADHSRTAAILIADG
MMAR_2170|M.marinum_M               DLLRPIIDLVAARAPRGYD----QGNHADDVRYRIIADHSRTAAILIADG
MLBr_00512|M.leprae_Br4923          DLLRPVIDLVATRAPRPYDPENEDTNHADNVRYRIIADHSRTAAILIGDG
TH_0114|M.thermoresistible__bu      DLIRPVIDLVAGLAPRGYG----QGSHSDDVRYRIIADHSRTAAILIGDG
MAB_2851c|M.abscessus_ATCC_199      DLVRPVIDCVAAVAPRGYG----QGNHEDDVRYRVIGDHARTAAIIIGDG
                                    **:** ** **  *.* *.       * *:****:*.**:*****:*.**

Mflv_3763|M.gilvum_PYR-GCK          VTPGNEGRGYVLRRLLRRIIRAAKLLGVEQPIMGELMATVRDEMGPSYPE
Mvan_2640|M.vanbaalenii_PYR-1       VSPGNEGRGYVLRRLLRRIIRAAKLLGVDDPIMAELMATVRDAMSPSYPE
MSMEG_3025|M.smegmatis_MC2_155      VSPGNEGRGYVLRRLLRRIIRAAKLLGVEQPVMGDLIATVRDAMGPSYPE
Mb2585c|M.bovis_AF2122/97           VSPGNDGRGYVLRRLLRRVIRSAKLLGIDAAIVGDLMATVRNAMGPSYPE
Rv2555c|M.tuberculosis_H37Rv        VSPGNDGRGYVLRRLLRRVIRSAKLLGIDAAIVGDLMATVRNAMGPSYPE
MAV_3431|M.avium_104                VTPGNDGRGYVLRRLLRRVIRSARLLDIEGPIVGDLMATVRDAMGPSYPE
MUL_1754|M.ulcerans_Agy99           VSPGNDGRGYVLRRLLRRVIRSAKLLNIDTAIVGDLMATVRDAMGPSYPE
MMAR_2170|M.marinum_M               VSPGNDGRGYVLRRLLRRVIRSAKLLNIDTAIVGDLMATVRDAMGPSYPE
MLBr_00512|M.leprae_Br4923          VSPVNDGRGYVLRRLLRRIIRSAKLLGIDSPIVGDLMATVCNAMGRAYPG
TH_0114|M.thermoresistible__bu      VTPGNDGRGYVLRRLLRRVIRSAKLLDVDRPIVGDLMATVRDTMGPAYGN
MAB_2851c|M.abscessus_ATCC_199      VSPGNEGRGYVLRRLLRRIIRSTKLLGVEKPMMGELMAVVRDEMGPSYPE
                                    *:* *:************:**:::**.:: .::.:*:*.* : *. :*  

Mflv_3763|M.gilvum_PYR-GCK          LVTDFERINRIAIAEETAFNRTLTAGSRLFEDAAETTRKAGSTVLSGDDA
Mvan_2640|M.vanbaalenii_PYR-1       LAADFDRIQRIAVAEETAFNRTLASGSKLFDDAARATKASGAEKLSGRDA
MSMEG_3025|M.smegmatis_MC2_155      LVTDFERINRIAVAEETAFNRTLASGSKLFEDAARATKKSGATVLSGSDA
Mb2585c|M.bovis_AF2122/97           LVADFERISRIAVAEETAFNRTLASGSRLFEEVASSTKKSGATVLSGSDA
Rv2555c|M.tuberculosis_H37Rv        LVADFERISRIAVAEETAFNRTLASGSRLFEEVASSTKKSGATVLSGSDA
MAV_3431|M.avium_104                LVTDFDRIARIAVAEETAFNRTLAAGSKLFDEVASTTKATGAKSISGSDA
MUL_1754|M.ulcerans_Agy99           LASDSDRINRIAVAEETAFNRTLASGSRLFDEVAGATRSSGVSVVSGSDA
MMAR_2170|M.marinum_M               LASDFDRINRIAVAEETAFNRTLASGSRLFDEVAGTTRSSGVSVVSGSDA
MLBr_00512|M.leprae_Br4923          LVTDFDRINRIAVAEETAFNRTLTSGSKLFDDVVGATVASGSTVVAGLDA
TH_0114|M.thermoresistible__bu      LISDFDRIHRIAVAEETAFNRTLSSGSKLFEEAAKATKAAGATVLSGKDA
MAB_2851c|M.abscessus_ATCC_199      LVTDFERISRIAVAEETAFNRTLASGSKLFEDAADKTKTAGKSTLSGSDA
                                    * :* :** ***:**********::**:**::..  *  :*   ::* **

Mflv_3763|M.gilvum_PYR-GCK          FTLHDTFGFPIDLTLEMAAEAGLSVDEEGFRGLMAEQRRRAKADAAARKQ
Mvan_2640|M.vanbaalenii_PYR-1       FTLHDTYGFPIELTLEMAAEADLSVDEEGFRALMAEQRQRAKADAAARKQ
MSMEG_3025|M.smegmatis_MC2_155      FTLHDTYGFPIDLTLEMAAEAGLSVDQEGFRTLMAEQRQRAKADAAARKQ
Mb2585c|M.bovis_AF2122/97           FTLHDTYGFPIELTLEMAAETGLQVDEIGFRELMAEQRRRAKADAAARKH
Rv2555c|M.tuberculosis_H37Rv        FTLHDTYGFPIELTLEMAAETGLQVDEIGFRELMAEQRRRAKADAAARKH
MAV_3431|M.avium_104                FTLHDTYGFPIELTLEMASEAGLQVDEVGFRELMAEQRRRAKADAAARKH
MUL_1754|M.ulcerans_Agy99           FTLHDTYGFPIELTLEMASEAGLTVDEGGFRELMAQQRRRAKADAAARKH
MMAR_2170|M.marinum_M               FTLHDTYGFPIELTLEMASEAGLTVDEGGFRELMAQQRRRAKADAAARKH
MLBr_00512|M.leprae_Br4923          FTLHDTYGFPIELTLEMAAEAGLTVDEKGFHELMLQQRQRAKVDAAARKQ
TH_0114|M.thermoresistible__bu      FTLHDTYGFPLELTLEMAAEAGLSVDEEGFRTLMAEQRERAKADAAARKQ
MAB_2851c|M.abscessus_ATCC_199      FTLHDTYGFPIELTLEMAAEAGLSVDEKGFRELMNEQRQRAKADAAARKH
                                    ******:***::******:*:.* **: **: ** :**.***.******:

Mflv_3763|M.gilvum_PYR-GCK          AHTDLSAYRELVDAGPTEFTGFDELTTEARILGIFVDGRRVPVVSHVQG-
Mvan_2640|M.vanbaalenii_PYR-1       AHADLSAYRELVDAGPTEFTGFDELSSEARILGIFVDGKRVPVVAHTGR-
MSMEG_3025|M.smegmatis_MC2_155      AHTDLSAYRELVDAGPTEFTGFDELTSEATILGIFVDGKRVPVVSHDG--
Mb2585c|M.bovis_AF2122/97           AHADLSAYRELVDAGATEFTGFDELRSQARILGIFVDGKRVPVVAHG--V
Rv2555c|M.tuberculosis_H37Rv        AHADLSAYRELVDAGATEFTGFDELRSQARILGIFVDGKRVPVVAHG--V
MAV_3431|M.avium_104                AHADLTAYRELVDAGPTEFTGFDELSSEARILGIFVDGKRVPVVTHG--G
MUL_1754|M.ulcerans_Agy99           AHADLTAYRELVDAGPTEFTGFDELTSEARILGIFVDGKRVPVVAH----
MMAR_2170|M.marinum_M               AHADLTAYRELVDAGPTEFTGFDELTSEARILGIFVDGKRVPVVAH----
MLBr_00512|M.leprae_Br4923          AHVDLTAYRELVDAGPTEFTGFDELTTEARILGIFVEGKRVPVVAHA--V
TH_0114|M.thermoresistible__bu      AHADLSAYRELVDAGPTEFTGFDELTSEAKILGIFVDGQRVPVVSHLPRV
MAB_2851c|M.abscessus_ATCC_199      AHADLSAYRELVDAGPTEFTGFDELDSAARILGIFVDGARVPVASAG---
                                    **.**:*********.********* : * ******:* ****.:     

Mflv_3763|M.gilvum_PYR-GCK          ---GDAPGRVELILNRSPFYAESGGQIADEGTVTGTGASQTAKAAVTDVQ
Mvan_2640|M.vanbaalenii_PYR-1       ---EGAQERVELILDRSPFYAESGGQIADEGTVTGTGASETAKAAVTDVQ
MSMEG_3025|M.smegmatis_MC2_155      ----LEADRVELILDRTPFYAEAGGQIADEGTISGTGASGTARAAVTDVQ
Mb2585c|M.bovis_AF2122/97           AGGAGEGQRVELVLDRTPLYAESGGQIADEGTISGTGSSEAARAAVTDVQ
Rv2555c|M.tuberculosis_H37Rv        AGGAGEGQRVELVLDRTPLYAESGGQIADEGTISGTGSSEAARAAVTDVQ
MAV_3431|M.avium_104                DG----ADRVELVLDRTPLYAESGGQIADEGTISGTGAGESARAAVTDVQ
MUL_1754|M.ulcerans_Agy99           -GQAVDADRVELVLDRTPLYAESGGQIADVGTISGTGSGSSARAAVTDVQ
MMAR_2170|M.marinum_M               -GQAVDADRVELVLDRTPLYAESGGQIADVGTISGTGSGSSARAAVTDVQ
MLBr_00512|M.leprae_Br4923          RGQAGITNRVELVLDRTPLYAESGGQIADAGTISGIGAGASSRAAVTDVQ
TH_0114|M.thermoresistible__bu      RSQSPPPQQVEIVLDRTPFYAESGGQIADEGTITGTGSSMAARARVTDVQ
MAB_2851c|M.abscessus_ATCC_199      -------SEAEIVLDRTPLYAESGGQIADVGSIRGDGANATSQAKVSDVQ
                                            ..*::*:*:*:***:****** *:: * *:. :::* *:***

Mflv_3763|M.gilvum_PYR-GCK          KIAKTLWAHRITVESGEFVEGDTIVAAVDPRWRHGATQGHSGTHMVHAAL
Mvan_2640|M.vanbaalenii_PYR-1       KIAKTLWAHRINVESGEFVEGDTVVAAVDPRWRHGATQGHSGTHMVHAAL
MSMEG_3025|M.smegmatis_MC2_155      KIARTLWAHRVNVESGEFVEGDTVTAAVDPKWRRGATQGHSGTHMVHAAL
Mb2585c|M.bovis_AF2122/97           KIAKTLWVHRVNVESGEFVEGDTVIAAVDPGWRRGATQGHSGTHMVHAAL
Rv2555c|M.tuberculosis_H37Rv        KIAKTLWVHRVNVESGEFVEGDTVIAAVDPGWRRGATQGHSGTHMVHAAL
MAV_3431|M.avium_104                KIAKTLWVHRVNVESGEFVEGDTVIAAVDPQWRRGATQGHSGTHMVHAAL
MUL_1754|M.ulcerans_Agy99           KIAKTLWLHRVNVESGEFVEGDGVVAAADAGWRKGATQGHSGTHMVHAAL
MMAR_2170|M.marinum_M               KIAKTLWLHRVNVESGEFVEGDGVVAAADAGWRKGATQGHSGTHMVHAAL
MLBr_00512|M.leprae_Br4923          KIAKTLHVHRVNLESGEFVEGDTVVAVVDPGWRRGAAQGHSGTHIVHAAL
TH_0114|M.thermoresistible__bu      KIANTLFVHRVSMESGEFVEGDTVIAAVDPEWRRGATQGHSGTHMVHAAL
MAB_2851c|M.abscessus_ATCC_199      KIAKTLFVHKVTVESGEFVEGDQVVASVDPHWRHGATQGHSGTHMVHAAL
                                    ***.**  *::.:********* : * .*. **:**:*******:*****

Mflv_3763|M.gilvum_PYR-GCK          RQVLGPNAVQAGSLNRPGYLRFDFNWQGALSDDQRSQIEEVTNEAVEADY
Mvan_2640|M.vanbaalenii_PYR-1       RQVLGPNAVQAGSLNRPGYLRFDFNWQGALTDDQRSQIEEVTNQAVEADF
MSMEG_3025|M.smegmatis_MC2_155      REVLGPNAVQAGSLNRPGYLRFDFNWQGPLSDDQRTQIEEVTNQAVEADY
Mb2585c|M.bovis_AF2122/97           RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTDDQRTQVEEVTNEAVQADF
Rv2555c|M.tuberculosis_H37Rv        RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTDDQRTQVEEVTNEAVQADF
MAV_3431|M.avium_104                RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTEEQRTQIEEVTNQAVQADF
MUL_1754|M.ulcerans_Agy99           RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTEEQRGQIEEVTNQAVQADF
MMAR_2170|M.marinum_M               RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTEEQRGQIEEVTNQAVQADF
MLBr_00512|M.leprae_Br4923          RQVLGPNAVQAGSLNRPGYLRFDFNWQGSLTGEQRTQIEEVTNEAVQADF
TH_0114|M.thermoresistible__bu      RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLSEQQRTQIEEVTNEAVQADF
MAB_2851c|M.abscessus_ATCC_199      RQVLGPNAVQAGSLNRPGYLRFDFSWQGALSEAQRQEVEDVANKAVEANY
                                    *:**********************.***.*:  ** ::*:*:*:**:*::

Mflv_3763|M.gilvum_PYR-GCK          EVHNFTTELEKAKSMGAMALFGENYPDEVRVVEIGGPFSIELCGGTHVRS
Mvan_2640|M.vanbaalenii_PYR-1       EVHSFTTELDKAKAMGAMALFGENYPDEVRVVEIGGPFSLELCGGTHVRS
MSMEG_3025|M.smegmatis_MC2_155      EVHTFVTELEKAKAMGAMAMFGERYPDQVRVVEIGGPFSLELCGGTHVHN
Mb2585c|M.bovis_AF2122/97           EVRTFTEQLDKAKAMGAIALFGESYPDEVRVVEMGGPFSLELCGGTHVSN
Rv2555c|M.tuberculosis_H37Rv        EVRTFTEQLDKAKAMGAIALFGESYPDEVRVVEMGGPFSLELCGGTHVSN
MAV_3431|M.avium_104                EVHTFTEQLEKAKAMGAIALFGESYPEQVRVVEIGGPFSLELCGGTHVHN
MUL_1754|M.ulcerans_Agy99           AVHTFTEQLEKAKAMGAMALFGECYPDEVRVVEIGGPFSIELCGGTHVAT
MMAR_2170|M.marinum_M               AVHTFTEQLEKAKAMGAMALFGESYPDEVRVVEIGGPFSIELCGGTHVAT
MLBr_00512|M.leprae_Br4923          EVHTFTEKLDTAKAMGAIALFGEAYPDEVRVVEMGGPFSLELCGGTHVHN
TH_0114|M.thermoresistible__bu      EVNTFITELEKAKSMGAIAMFGEKYPERVRVVEIGGPFSLELCGGTHVES
MAB_2851c|M.abscessus_ATCC_199      PVNTFVTDLDQAKSMGAMALFGENYGDRVRVVDIGGPFSLELCGGTHVAH
                                     *..*  .*: **:***:*:*** * :.****::*****:********  

Mflv_3763|M.gilvum_PYR-GCK          SAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
Mvan_2640|M.vanbaalenii_PYR-1       SAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
MSMEG_3025|M.smegmatis_MC2_155      SAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
Mb2585c|M.bovis_AF2122/97           TAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
Rv2555c|M.tuberculosis_H37Rv        TAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
MAV_3431|M.avium_104                SAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
MUL_1754|M.ulcerans_Agy99           SAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
MMAR_2170|M.marinum_M               SAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
MLBr_00512|M.leprae_Br4923          TAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLQV
TH_0114|M.thermoresistible__bu      SAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLSKERALMAAVASTLKV
MAB_2851c|M.abscessus_ATCC_199      SSQIGPVTLLGESSVGSGVRRVEAYVGLDAVRYLSKERALMAALSSSLKV
                                    ::******:*****:**************:.*:*:*******.::*:*:*

Mflv_3763|M.gilvum_PYR-GCK          PSDEVPARVENLVERLRAAEKELDRLRLVNARAAAANAAAGAEQIGGIRL
Mvan_2640|M.vanbaalenii_PYR-1       PSEEVPARVATLVEKLRAAEKELDRLRLAGARSAAVNAAAGAEQIGDVRL
MSMEG_3025|M.smegmatis_MC2_155      PSEEVPARVANLVERLKAAEKELDRMRLANARAAAVNAVAGAETVGKVRL
Mb2585c|M.bovis_AF2122/97           PSEEVPARVANLVERLRAAEKELERVRMASARAAATNAAAGAQRIGNVRL
Rv2555c|M.tuberculosis_H37Rv        PSEEVPARVANLVERLRAAEKELERVRMASARAAATNAAAGAQRIGNVRL
MAV_3431|M.avium_104                PSEEVPARVANLVERLRAAEKELERMRLASARAAAGNAAAGAERIGNVRV
MUL_1754|M.ulcerans_Agy99           PSEEVPARVASLVERLKAAEKELERARLASVRAAAVNAAAGAERIGNVRL
MMAR_2170|M.marinum_M               PSEEVPARVASLVERLKAAEKELERARLASVRAAAVNAAAGAERIGNVWL
MLBr_00512|M.leprae_Br4923          PSEEVHARVATLVERLKAAEKELERARQANVQAAATKAAAGAEWIGNVRV
TH_0114|M.thermoresistible__bu      PSEEVPDRVANLVEKLRAAEKELERLRLANAKAAVSDAVAQAEQVGRVRL
MAB_2851c|M.abscessus_ATCC_199      PSEEVPGRVATLVERLKVAEKELEQTRLASVKASIATLVDNAERIGSVTV
                                    **:**  ** .***:*:.*****:: * ...:::    .  *: :* : :

Mflv_3763|M.gilvum_PYR-GCK          VAQRMAGGISAGDLRSLVGDIRGKLGSDPAVVALISE---ADDDTVPFVV
Mvan_2640|M.vanbaalenii_PYR-1       VAQRMAGGISGADLRSLVGEIRGKLGSDPAVVALIAE---GDNDSVPFVV
MSMEG_3025|M.smegmatis_MC2_155      VAQRMSGGMSANDLRSLVGDIRGKLGSEPAVVALIAE---GENDAVPFVV
Mb2585c|M.bovis_AF2122/97           VAQRMSGGMTAADLRSLIGDIRGKLGSEPAVVALIAE---GESQTVPYAV
Rv2555c|M.tuberculosis_H37Rv        VAQRMSGGMTAADLRSLIGDIRGKLGSEPAVVALIAE---GESQTVPYAV
MAV_3431|M.avium_104                VAQRMSGGMTAADLRSLVGDIRGKLGSDPAVVALIAE---GEGGSVPYAV
MUL_1754|M.ulcerans_Agy99           VAQRMSSEMTPADLRTLVGDIRGKLGSDPAVVALIAAPAGGESSTVPYVV
MMAR_2170|M.marinum_M               VAQRMSSEMTPADLRTLVGDIRGKLGSDPAVVALIAAPAGGESSTVPYVV
MLBr_00512|M.leprae_Br4923          VVQRMSGPIAPDDLRFLVGDIRGKLGSDPAVVALIAVTSDGPTATVPYAV
TH_0114|M.thermoresistible__bu      VARRIDAGLNAGELRNLVGDIRGKLGSDPAVVALMAAT---DDGSVPFVV
MAB_2851c|M.abscessus_ATCC_199      VAHRLPDGTGAGDLRSLVGDIRGRLGSDPAVVALIAAG----EGSVPFVV
                                    *.:*:       :** *:*:***:***:******::        :**:.*

Mflv_3763|M.gilvum_PYR-GCK          AVNQAAQDRGLRANDLVKVLGAAVNGRGGGKADLAQGSGKGAAGIDAALA
Mvan_2640|M.vanbaalenii_PYR-1       AVNPAAQDRGVRADELVKVMGAAVNGRGGGKADLAQGSGKGAAGIDAALA
MSMEG_3025|M.smegmatis_MC2_155      AVNPAAQDLGLRANDLVKQFAAPVNGRGGGKADLAQGSGKGAAGIDAALA
Mb2585c|M.bovis_AF2122/97           AANPAAQDLGIRANDLVKQLAVAVEGRGGGKADLAQGSGKNPTGIDAALD
Rv2555c|M.tuberculosis_H37Rv        AANPAAQDLGIRANDLVKQLAVAVEGRGGGKADLAQGSGKNPTGIDAALD
MAV_3431|M.avium_104                AANPAAQDLGIRANDLVKQLAAPVDGRGGGKADLAQGSGKDPAGIDAALD
MUL_1754|M.ulcerans_Agy99           AANQAAQGLGLGANELIKHLAAAVDGRGGGKADLAQGSGKKPAGIAAALE
MMAR_2170|M.marinum_M               AANRAAQGLGLGANELIKHLATAVDGRGGGKADLAQGSGKKPAGIDAALE
MLBr_00512|M.leprae_Br4923          AANPAAQDLGIRANDLVEQLAMVVDGRGGGKADLAQGSGKDPTGIDAALD
TH_0114|M.thermoresistible__bu      AVNPAAQDLGLRANNLVKVLAPEVDGRGGGKVDLAQGSGKKAAGIDAALA
MAB_2851c|M.abscessus_ATCC_199      SVNQAAQDAGLRANDLVGAIGPAVDGRGGGKADTAQGSGKDPAGIDAALQ
                                    :.* ***. *: *::*:  :.  *:******.* ****** .:** *** 

Mflv_3763|M.gilvum_PYR-GCK          AIR---AEMGRS-
Mvan_2640|M.vanbaalenii_PYR-1       AIR---AEIGRS-
MSMEG_3025|M.smegmatis_MC2_155      ALR---AEIGRS-
Mb2585c|M.bovis_AF2122/97           AVRSEIAVIARVG
Rv2555c|M.tuberculosis_H37Rv        AVRSEIAVIARVG
MAV_3431|M.avium_104                AVRSEIAAIARVG
MUL_1754|M.ulcerans_Agy99           ALR---AEIARVG
MMAR_2170|M.marinum_M               ALR---AEIARVG
MLBr_00512|M.leprae_Br4923          TVR---AQIAQVG
TH_0114|M.thermoresistible__bu      ALR---AEIARS-
MAB_2851c|M.abscessus_ATCC_199      ALR---AQIRRA-
                                    ::*   * : :