For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_3025 (alaS)

annotation: alanyl-tRNA synthetase
coordinates: 3096983 - 3099673
length: 896

VQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLGQRTPPWNRATSIQKCIRTPD
IDEVGITTRHNTFFQMAGNFSFGDYFKRGAIELAWTLLTNPVEEGGYGFDPERLWATVYLDDDEAIGLWQ
EVAGLPAERIQRRGMADNYWSMGIPGPCGPSSEIYYDRGPEYGVEGGPEANEDRYIEIWNLVFMQNERGE
GTSKEDFEILGPLPRKNIDTGMGIERVACLLQGVDNVYETDLLRPVIDKVAAVAPRGYGAGNHDDDVRYR
IIADHTRTAAIIIADGVSPGNEGRGYVLRRLLRRIIRAAKLLGVEQPVMGDLIATVRDAMGPSYPELVTD
FERINRIAVAEETAFNRTLASGSKLFEDAARATKKSGATVLSGSDAFTLHDTYGFPIDLTLEMAAEAGLS
VDQEGFRTLMAEQRQRAKADAAARKQAHTDLSAYRELVDAGPTEFTGFDELTSEATILGIFVDGKRVPVV
SHDGLEADRVELILDRTPFYAEAGGQIADEGTISGTGASGTARAAVTDVQKIARTLWAHRVNVESGEFVE
GDTVTAAVDPKWRRGATQGHSGTHMVHAALREVLGPNAVQAGSLNRPGYLRFDFNWQGPLSDDQRTQIEE
VTNQAVEADYEVHTFVTELEKAKAMGAMAMFGERYPDQVRVVEIGGPFSLELCGGTHVHNSAQIGPVTIL
GESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKVPSEEVPARVANLVERLKAAEKELDRMRLAN
ARAAAVNAVAGAETVGKVRLVAQRMSGGMSANDLRSLVGDIRGKLGSEPAVVALIAEGENDAVPFVVAVN
PAAQDLGLRANDLVKQFAAPVNGRGGGKADLAQGSGKGAAGIDAALAALRAEIGRS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3025alaS-100% (896)alanyl-tRNA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2585calaS0.083.95% (897) alanyl-tRNA synthetase
M. gilvum PYR-GCKMflv_3763alaS0.088.20% (898) alanyl-tRNA synthetase
M. tuberculosis H37RvRv2555calaS0.084.06% (897) alanyl-tRNA synthetase
M. leprae Br4923MLBr_00512alaS0.079.71% (907) alanyl-tRNA synthetase
M. abscessus ATCC 19977MAB_2851calaS0.081.36% (896) alanyl-tRNA synthetase
M. marinum MMMAR_2170alaS0.083.43% (899) alanyl-tRNA synthetase AlaS
M. avium 104MAV_3431alaS0.086.11% (893) alanyl-tRNA synthetase
M. thermoresistible (build 8)TH_0114alaS0.083.59% (902) PROBABLE ALANYL-TRNA SYNTHETASE ALAS (ALANINE--TRNA LIGASE)
M. ulcerans Agy99MUL_1754alaS0.083.54% (899) alanyl-tRNA synthetase
M. vanbaalenii PYR-1Mvan_2640alaS0.088.86% (898) alanyl-tRNA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3763|M.gilvum_PYR-GCK          MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLG
Mvan_2640|M.vanbaalenii_PYR-1       MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLG
MSMEG_3025|M.smegmatis_MC2_155      MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLG
MMAR_2170|M.marinum_M               MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
MUL_1754|M.ulcerans_Agy99           MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
MLBr_00512|M.leprae_Br4923          MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
Mb2585c|M.bovis_AF2122/97           MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
Rv2555c|M.tuberculosis_H37Rv        MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
MAV_3431|M.avium_104                MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLG
TH_0114|M.thermoresistible__bu      VQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLG
MAB_2851c|M.abscessus_ATCC_199      MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLG
                                    :*********************************************:***

Mflv_3763|M.gilvum_PYR-GCK          QRTPPWDRATSVQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKKGA
Mvan_2640|M.vanbaalenii_PYR-1       QRTPPWDRAASVQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKKGA
MSMEG_3025|M.smegmatis_MC2_155      QRTPPWNRATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
MMAR_2170|M.marinum_M               QRTPPYATATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
MUL_1754|M.ulcerans_Agy99           QRTPPYATATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
MLBr_00512|M.leprae_Br4923          QCTPPYATATSIQKCIRTPDIDDVGITTRHNTFFQMAGNFSFGDYFKRGA
Mb2585c|M.bovis_AF2122/97           QRTPPYPTATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
Rv2555c|M.tuberculosis_H37Rv        QRTPPYPTATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
MAV_3431|M.avium_104                ARTPPYPTATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKREA
TH_0114|M.thermoresistible__bu      QRTPPYTRATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGA
MAB_2851c|M.abscessus_ATCC_199      QRTPPYNTATSVQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKREA
                                      ***:  *:*:**********:************************: *

Mflv_3763|M.gilvum_PYR-GCK          IELAWSLLTNPVSEGGYGFDPERLWATVYLDDDEAIELWQEVAGLPAERI
Mvan_2640|M.vanbaalenii_PYR-1       IEFAWTLLTNPVEAGGYGFDPERLWATVYLDDDEAIGYWQEVAGLPLERI
MSMEG_3025|M.smegmatis_MC2_155      IELAWTLLTNPVEEGGYGFDPERLWATVYLDDDEAIGLWQEVAGLPAERI
MMAR_2170|M.marinum_M               IELAWALLTNSVADGGYGLDPEKLWATVYLDDDEAAGLWREVAGLPADRI
MUL_1754|M.ulcerans_Agy99           IELAWALLTNSVADGGYGLDPEKLWATVYLDDDEAAGLWREVAGLPADRI
MLBr_00512|M.leprae_Br4923          IELAWALLTNSFADGGYGLDPERLWATVYLDDDEAAGLWQEIAGLPPERI
Mb2585c|M.bovis_AF2122/97           IELAWALLTNSLAAGGYGLDPERIWTTVYFDDDEAVRLWQEVAGLPAERI
Rv2555c|M.tuberculosis_H37Rv        IELAWALLTNSLAAGGYGLDPERIWTTVYFDDDEAVRLWQEVAGLPAERI
MAV_3431|M.avium_104                IELAWTLLTGSVEQGGYGLDPERIWTTVYFDDDEAVRLWQEIAGLPAERI
TH_0114|M.thermoresistible__bu      IEYAWSLLTKSVDDGGYGFDPEKIWATVYLDDDEAADLWQEIAGLPPERI
MAB_2851c|M.abscessus_ATCC_199      IRLAWTLLTNPVSEGGYGFDPEKLWATVYLDDDEAIGLWQEVAGLPLDRI
                                    *. **:*** ..  ****:***::*:***:*****   *:*:**** :**

Mflv_3763|M.gilvum_PYR-GCK          QRRGMADNYWSMGIPGPCGPCSEIYYDRGPDYGIDGGPEANEDRYIEIWN
Mvan_2640|M.vanbaalenii_PYR-1       QRRGMADNYWSMGIPGPCGPSSEIYYDRGPEYGIEGGPEANEDRYIEIWN
MSMEG_3025|M.smegmatis_MC2_155      QRRGMADNYWSMGIPGPCGPSSEIYYDRGPEYGVEGGPEANEDRYIEIWN
MMAR_2170|M.marinum_M               QRRGMADNYWSMGIPGPCGPSSEIYYDRGPDYGPEGGPVVNEDRYLEIWN
MUL_1754|M.ulcerans_Agy99           QRRGMADNYWSMGIPGPCGPSSEIYYDRGPDYGPEGGPVVNEDRYLEIWN
MLBr_00512|M.leprae_Br4923          QRRGMADNYWSMGIPGPCGPSSEIYYDRGPEFGPEGGPIVNEDRYLEVWN
Mb2585c|M.bovis_AF2122/97           QRRGMADNYWSMGIPGPCGPSSEIYYDRGPEFGPAGGPIVSEDRYLEVWN
Rv2555c|M.tuberculosis_H37Rv        QRRGMADNYWSMGIPGPCGPSSEIYYDRGPEFGPAGGPIVSEDRYLEVWN
MAV_3431|M.avium_104                QRRGMEDNYWSMGIPGPCGPSSEIYYDRGEEFGVGGGPIANEDRYVELWN
TH_0114|M.thermoresistible__bu      QRRGMADNYWSMGIPGPCGPSSEIYYDRGPDYGVEGGPIANEDRYIEIWN
MAB_2851c|M.abscessus_ATCC_199      QRRGMADNYWSMGIPGPCGPCSEIYYDRGPEYGIEGGPEANEDRYIEIWN
                                    ***** **************.******** ::*  *** ..****:*:**

Mflv_3763|M.gilvum_PYR-GCK          LVFMQNERGEGTSKDDFEILGPLPRKNIDTGMGVERIACLLQGVDNVYET
Mvan_2640|M.vanbaalenii_PYR-1       LVFMQNERGEGTSKEDFEILGPLPRKNIDTGMGVERVACLLQGVDNVYET
MSMEG_3025|M.smegmatis_MC2_155      LVFMQNERGEGTSKEDFEILGPLPRKNIDTGMGIERVACLLQGVDNVYET
MMAR_2170|M.marinum_M               LVFMQNERGEGTTKEDYEILGPLPRKNIDTGMGVERVALILQGVPNVYET
MUL_1754|M.ulcerans_Agy99           LVFMQNERGEGTTKEDYEILGPLPRKNIDTGMGVERVALILQGVPNVYET
MLBr_00512|M.leprae_Br4923          LVFMQNERGEGTTKEDYEIRGPLPRKNIDTGMGVERIALVLQGVHNVYEI
Mb2585c|M.bovis_AF2122/97           LVFMQNERGEGTTKEDYQILGPLPRNNIDTGMGVERIALVLQDVHNVYET
Rv2555c|M.tuberculosis_H37Rv        LVFMQNERGEGTTKEDYQILGPLPRKNIDTGMGVERIALVLQDVHNVYET
MAV_3431|M.avium_104                LVFMQSERGEGTSKTDFEILGPLPRKNIDTGMGVERVAFVLQGVHNVYET
TH_0114|M.thermoresistible__bu      LVFMENERGAGPAKEGYEILGPLPRKNIDTGMGIERVACLLQGVDNVYET
MAB_2851c|M.abscessus_ATCC_199      LVFMQNERGEGTSKTDFEILGPLPRQNIDTGMGVERIACLLQGVDNVYET
                                    ****:.*** *.:* .::* *****:*******:**:* :**.* **** 

Mflv_3763|M.gilvum_PYR-GCK          DLVRPVIDLVAGIAPRGYG----QGNHTDDVRYRIIGDHSRTAAIIIGDG
Mvan_2640|M.vanbaalenii_PYR-1       DLLRPAIDLVAGIAPRGYG----QGVHEDDVRYRIIADHSRTAAIIIGDG
MSMEG_3025|M.smegmatis_MC2_155      DLLRPVIDKVAAVAPRGYG----AGNHDDDVRYRIIADHTRTAAIIIADG
MMAR_2170|M.marinum_M               DLLRPIIDLVAARAPRGYD----QGNHADDVRYRIIADHSRTAAILIADG
MUL_1754|M.ulcerans_Agy99           DLLRPIIDLVAARAPRGYD----QGNHADDVRYRIIADHSRTAAILIADG
MLBr_00512|M.leprae_Br4923          DLLRPVIDLVATRAPRPYDPENEDTNHADNVRYRIIADHSRTAAILIGDG
Mb2585c|M.bovis_AF2122/97           DLLRPVIDTVARVAARAYD----VGNHEDDVRYRIIADHSRTAAILIGDG
Rv2555c|M.tuberculosis_H37Rv        DLLRPVIDTVARVAARAYD----VGNHEDDVRYRIIADHSRTAAILIGDG
MAV_3431|M.avium_104                DLLRPVIDAVAARAPRPYD----AGNHDDDVRYRIIADHSRTAAILIGDG
TH_0114|M.thermoresistible__bu      DLIRPVIDLVAGLAPRGYG----QGSHSDDVRYRIIADHSRTAAILIGDG
MAB_2851c|M.abscessus_ATCC_199      DLVRPVIDCVAAVAPRGYG----QGNHEDDVRYRVIGDHARTAAIIIGDG
                                    **:** ** **  *.* *.       * *:****:*.**:*****:*.**

Mflv_3763|M.gilvum_PYR-GCK          VTPGNEGRGYVLRRLLRRIIRAAKLLGVEQPIMGELMATVRDEMGPSYPE
Mvan_2640|M.vanbaalenii_PYR-1       VSPGNEGRGYVLRRLLRRIIRAAKLLGVDDPIMAELMATVRDAMSPSYPE
MSMEG_3025|M.smegmatis_MC2_155      VSPGNEGRGYVLRRLLRRIIRAAKLLGVEQPVMGDLIATVRDAMGPSYPE
MMAR_2170|M.marinum_M               VSPGNDGRGYVLRRLLRRVIRSAKLLNIDTAIVGDLMATVRDAMGPSYPE
MUL_1754|M.ulcerans_Agy99           VSPGNDGRGYVLRRLLRRVIRSAKLLNIDTAIVGDLMATVRDAMGPSYPE
MLBr_00512|M.leprae_Br4923          VSPVNDGRGYVLRRLLRRIIRSAKLLGIDSPIVGDLMATVCNAMGRAYPG
Mb2585c|M.bovis_AF2122/97           VSPGNDGRGYVLRRLLRRVIRSAKLLGIDAAIVGDLMATVRNAMGPSYPE
Rv2555c|M.tuberculosis_H37Rv        VSPGNDGRGYVLRRLLRRVIRSAKLLGIDAAIVGDLMATVRNAMGPSYPE
MAV_3431|M.avium_104                VTPGNDGRGYVLRRLLRRVIRSARLLDIEGPIVGDLMATVRDAMGPSYPE
TH_0114|M.thermoresistible__bu      VTPGNDGRGYVLRRLLRRVIRSAKLLDVDRPIVGDLMATVRDTMGPAYGN
MAB_2851c|M.abscessus_ATCC_199      VSPGNEGRGYVLRRLLRRIIRSTKLLGVEKPMMGELMAVVRDEMGPSYPE
                                    *:* *:************:**:::**.:: .::.:*:*.* : *. :*  

Mflv_3763|M.gilvum_PYR-GCK          LVTDFERINRIAIAEETAFNRTLTAGSRLFEDAAETTRKAGSTVLSGDDA
Mvan_2640|M.vanbaalenii_PYR-1       LAADFDRIQRIAVAEETAFNRTLASGSKLFDDAARATKASGAEKLSGRDA
MSMEG_3025|M.smegmatis_MC2_155      LVTDFERINRIAVAEETAFNRTLASGSKLFEDAARATKKSGATVLSGSDA
MMAR_2170|M.marinum_M               LASDFDRINRIAVAEETAFNRTLASGSRLFDEVAGTTRSSGVSVVSGSDA
MUL_1754|M.ulcerans_Agy99           LASDSDRINRIAVAEETAFNRTLASGSRLFDEVAGATRSSGVSVVSGSDA
MLBr_00512|M.leprae_Br4923          LVTDFDRINRIAVAEETAFNRTLTSGSKLFDDVVGATVASGSTVVAGLDA
Mb2585c|M.bovis_AF2122/97           LVADFERISRIAVAEETAFNRTLASGSRLFEEVASSTKKSGATVLSGSDA
Rv2555c|M.tuberculosis_H37Rv        LVADFERISRIAVAEETAFNRTLASGSRLFEEVASSTKKSGATVLSGSDA
MAV_3431|M.avium_104                LVTDFDRIARIAVAEETAFNRTLAAGSKLFDEVASTTKATGAKSISGSDA
TH_0114|M.thermoresistible__bu      LISDFDRIHRIAVAEETAFNRTLSSGSKLFEEAAKATKAAGATVLSGKDA
MAB_2851c|M.abscessus_ATCC_199      LVTDFERISRIAVAEETAFNRTLASGSKLFEDAADKTKTAGKSTLSGSDA
                                    * :* :** ***:**********::**:**::..  *  :*   ::* **

Mflv_3763|M.gilvum_PYR-GCK          FTLHDTFGFPIDLTLEMAAEAGLSVDEEGFRGLMAEQRRRAKADAAARKQ
Mvan_2640|M.vanbaalenii_PYR-1       FTLHDTYGFPIELTLEMAAEADLSVDEEGFRALMAEQRQRAKADAAARKQ
MSMEG_3025|M.smegmatis_MC2_155      FTLHDTYGFPIDLTLEMAAEAGLSVDQEGFRTLMAEQRQRAKADAAARKQ
MMAR_2170|M.marinum_M               FTLHDTYGFPIELTLEMASEAGLTVDEGGFRELMAQQRRRAKADAAARKH
MUL_1754|M.ulcerans_Agy99           FTLHDTYGFPIELTLEMASEAGLTVDEGGFRELMAQQRRRAKADAAARKH
MLBr_00512|M.leprae_Br4923          FTLHDTYGFPIELTLEMAAEAGLTVDEKGFHELMLQQRQRAKVDAAARKQ
Mb2585c|M.bovis_AF2122/97           FTLHDTYGFPIELTLEMAAETGLQVDEIGFRELMAEQRRRAKADAAARKH
Rv2555c|M.tuberculosis_H37Rv        FTLHDTYGFPIELTLEMAAETGLQVDEIGFRELMAEQRRRAKADAAARKH
MAV_3431|M.avium_104                FTLHDTYGFPIELTLEMASEAGLQVDEVGFRELMAEQRRRAKADAAARKH
TH_0114|M.thermoresistible__bu      FTLHDTYGFPLELTLEMAAEAGLSVDEEGFRTLMAEQRERAKADAAARKQ
MAB_2851c|M.abscessus_ATCC_199      FTLHDTYGFPIELTLEMAAEAGLSVDEKGFRELMNEQRQRAKADAAARKH
                                    ******:***::******:*:.* **: **: ** :**.***.******:

Mflv_3763|M.gilvum_PYR-GCK          AHTDLSAYRELVDAGPTEFTGFDELTTEARILGIFVDGRRVPVVSHVQG-
Mvan_2640|M.vanbaalenii_PYR-1       AHADLSAYRELVDAGPTEFTGFDELSSEARILGIFVDGKRVPVVAHTGR-
MSMEG_3025|M.smegmatis_MC2_155      AHTDLSAYRELVDAGPTEFTGFDELTSEATILGIFVDGKRVPVVSHDG--
MMAR_2170|M.marinum_M               AHADLTAYRELVDAGPTEFTGFDELTSEARILGIFVDGKRVPVVAH----
MUL_1754|M.ulcerans_Agy99           AHADLTAYRELVDAGPTEFTGFDELTSEARILGIFVDGKRVPVVAH----
MLBr_00512|M.leprae_Br4923          AHVDLTAYRELVDAGPTEFTGFDELTTEARILGIFVEGKRVPVVAHA--V
Mb2585c|M.bovis_AF2122/97           AHADLSAYRELVDAGATEFTGFDELRSQARILGIFVDGKRVPVVAHG--V
Rv2555c|M.tuberculosis_H37Rv        AHADLSAYRELVDAGATEFTGFDELRSQARILGIFVDGKRVPVVAHG--V
MAV_3431|M.avium_104                AHADLTAYRELVDAGPTEFTGFDELSSEARILGIFVDGKRVPVVTHG--G
TH_0114|M.thermoresistible__bu      AHADLSAYRELVDAGPTEFTGFDELTSEAKILGIFVDGQRVPVVSHLPRV
MAB_2851c|M.abscessus_ATCC_199      AHADLSAYRELVDAGPTEFTGFDELDSAARILGIFVDGARVPVASAG---
                                    **.**:*********.********* : * ******:* ****.:     

Mflv_3763|M.gilvum_PYR-GCK          ---GDAPGRVELILNRSPFYAESGGQIADEGTVTGTGASQTAKAAVTDVQ
Mvan_2640|M.vanbaalenii_PYR-1       ---EGAQERVELILDRSPFYAESGGQIADEGTVTGTGASETAKAAVTDVQ
MSMEG_3025|M.smegmatis_MC2_155      ----LEADRVELILDRTPFYAEAGGQIADEGTISGTGASGTARAAVTDVQ
MMAR_2170|M.marinum_M               -GQAVDADRVELVLDRTPLYAESGGQIADVGTISGTGSGSSARAAVTDVQ
MUL_1754|M.ulcerans_Agy99           -GQAVDADRVELVLDRTPLYAESGGQIADVGTISGTGSGSSARAAVTDVQ
MLBr_00512|M.leprae_Br4923          RGQAGITNRVELVLDRTPLYAESGGQIADAGTISGIGAGASSRAAVTDVQ
Mb2585c|M.bovis_AF2122/97           AGGAGEGQRVELVLDRTPLYAESGGQIADEGTISGTGSSEAARAAVTDVQ
Rv2555c|M.tuberculosis_H37Rv        AGGAGEGQRVELVLDRTPLYAESGGQIADEGTISGTGSSEAARAAVTDVQ
MAV_3431|M.avium_104                DG----ADRVELVLDRTPLYAESGGQIADEGTISGTGAGESARAAVTDVQ
TH_0114|M.thermoresistible__bu      RSQSPPPQQVEIVLDRTPFYAESGGQIADEGTITGTGSSMAARARVTDVQ
MAB_2851c|M.abscessus_ATCC_199      -------SEAEIVLDRTPLYAESGGQIADVGSIRGDGANATSQAKVSDVQ
                                            ..*::*:*:*:***:****** *:: * *:. :::* *:***

Mflv_3763|M.gilvum_PYR-GCK          KIAKTLWAHRITVESGEFVEGDTIVAAVDPRWRHGATQGHSGTHMVHAAL
Mvan_2640|M.vanbaalenii_PYR-1       KIAKTLWAHRINVESGEFVEGDTVVAAVDPRWRHGATQGHSGTHMVHAAL
MSMEG_3025|M.smegmatis_MC2_155      KIARTLWAHRVNVESGEFVEGDTVTAAVDPKWRRGATQGHSGTHMVHAAL
MMAR_2170|M.marinum_M               KIAKTLWLHRVNVESGEFVEGDGVVAAADAGWRKGATQGHSGTHMVHAAL
MUL_1754|M.ulcerans_Agy99           KIAKTLWLHRVNVESGEFVEGDGVVAAADAGWRKGATQGHSGTHMVHAAL
MLBr_00512|M.leprae_Br4923          KIAKTLHVHRVNLESGEFVEGDTVVAVVDPGWRRGAAQGHSGTHIVHAAL
Mb2585c|M.bovis_AF2122/97           KIAKTLWVHRVNVESGEFVEGDTVIAAVDPGWRRGATQGHSGTHMVHAAL
Rv2555c|M.tuberculosis_H37Rv        KIAKTLWVHRVNVESGEFVEGDTVIAAVDPGWRRGATQGHSGTHMVHAAL
MAV_3431|M.avium_104                KIAKTLWVHRVNVESGEFVEGDTVIAAVDPQWRRGATQGHSGTHMVHAAL
TH_0114|M.thermoresistible__bu      KIANTLFVHRVSMESGEFVEGDTVIAAVDPEWRRGATQGHSGTHMVHAAL
MAB_2851c|M.abscessus_ATCC_199      KIAKTLFVHKVTVESGEFVEGDQVVASVDPHWRHGATQGHSGTHMVHAAL
                                    ***.**  *::.:********* : * .*. **:**:*******:*****

Mflv_3763|M.gilvum_PYR-GCK          RQVLGPNAVQAGSLNRPGYLRFDFNWQGALSDDQRSQIEEVTNEAVEADY
Mvan_2640|M.vanbaalenii_PYR-1       RQVLGPNAVQAGSLNRPGYLRFDFNWQGALTDDQRSQIEEVTNQAVEADF
MSMEG_3025|M.smegmatis_MC2_155      REVLGPNAVQAGSLNRPGYLRFDFNWQGPLSDDQRTQIEEVTNQAVEADY
MMAR_2170|M.marinum_M               RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTEEQRGQIEEVTNQAVQADF
MUL_1754|M.ulcerans_Agy99           RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTEEQRGQIEEVTNQAVQADF
MLBr_00512|M.leprae_Br4923          RQVLGPNAVQAGSLNRPGYLRFDFNWQGSLTGEQRTQIEEVTNEAVQADF
Mb2585c|M.bovis_AF2122/97           RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTDDQRTQVEEVTNEAVQADF
Rv2555c|M.tuberculosis_H37Rv        RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTDDQRTQVEEVTNEAVQADF
MAV_3431|M.avium_104                RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTEEQRTQIEEVTNQAVQADF
TH_0114|M.thermoresistible__bu      RQVLGPNAVQAGSLNRPGYLRFDFNWQGPLSEQQRTQIEEVTNEAVQADF
MAB_2851c|M.abscessus_ATCC_199      RQVLGPNAVQAGSLNRPGYLRFDFSWQGALSEAQRQEVEDVANKAVEANY
                                    *:**********************.***.*:  ** ::*:*:*:**:*::

Mflv_3763|M.gilvum_PYR-GCK          EVHNFTTELEKAKSMGAMALFGENYPDEVRVVEIGGPFSIELCGGTHVRS
Mvan_2640|M.vanbaalenii_PYR-1       EVHSFTTELDKAKAMGAMALFGENYPDEVRVVEIGGPFSLELCGGTHVRS
MSMEG_3025|M.smegmatis_MC2_155      EVHTFVTELEKAKAMGAMAMFGERYPDQVRVVEIGGPFSLELCGGTHVHN
MMAR_2170|M.marinum_M               AVHTFTEQLEKAKAMGAMALFGESYPDEVRVVEIGGPFSIELCGGTHVAT
MUL_1754|M.ulcerans_Agy99           AVHTFTEQLEKAKAMGAMALFGECYPDEVRVVEIGGPFSIELCGGTHVAT
MLBr_00512|M.leprae_Br4923          EVHTFTEKLDTAKAMGAIALFGEAYPDEVRVVEMGGPFSLELCGGTHVHN
Mb2585c|M.bovis_AF2122/97           EVRTFTEQLDKAKAMGAIALFGESYPDEVRVVEMGGPFSLELCGGTHVSN
Rv2555c|M.tuberculosis_H37Rv        EVRTFTEQLDKAKAMGAIALFGESYPDEVRVVEMGGPFSLELCGGTHVSN
MAV_3431|M.avium_104                EVHTFTEQLEKAKAMGAIALFGESYPEQVRVVEIGGPFSLELCGGTHVHN
TH_0114|M.thermoresistible__bu      EVNTFITELEKAKSMGAIAMFGEKYPERVRVVEIGGPFSLELCGGTHVES
MAB_2851c|M.abscessus_ATCC_199      PVNTFVTDLDQAKSMGAMALFGENYGDRVRVVDIGGPFSLELCGGTHVAH
                                     *..*  .*: **:***:*:*** * :.****::*****:********  

Mflv_3763|M.gilvum_PYR-GCK          SAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
Mvan_2640|M.vanbaalenii_PYR-1       SAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
MSMEG_3025|M.smegmatis_MC2_155      SAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
MMAR_2170|M.marinum_M               SAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
MUL_1754|M.ulcerans_Agy99           SAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
MLBr_00512|M.leprae_Br4923          TAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLQV
Mb2585c|M.bovis_AF2122/97           TAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
Rv2555c|M.tuberculosis_H37Rv        TAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
MAV_3431|M.avium_104                SAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKV
TH_0114|M.thermoresistible__bu      SAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLSKERALMAAVASTLKV
MAB_2851c|M.abscessus_ATCC_199      SSQIGPVTLLGESSVGSGVRRVEAYVGLDAVRYLSKERALMAALSSSLKV
                                    ::******:*****:**************:.*:*:*******.::*:*:*

Mflv_3763|M.gilvum_PYR-GCK          PSDEVPARVENLVERLRAAEKELDRLRLVNARAAAANAAAGAEQIGGIRL
Mvan_2640|M.vanbaalenii_PYR-1       PSEEVPARVATLVEKLRAAEKELDRLRLAGARSAAVNAAAGAEQIGDVRL
MSMEG_3025|M.smegmatis_MC2_155      PSEEVPARVANLVERLKAAEKELDRMRLANARAAAVNAVAGAETVGKVRL
MMAR_2170|M.marinum_M               PSEEVPARVASLVERLKAAEKELERARLASVRAAAVNAAAGAERIGNVWL
MUL_1754|M.ulcerans_Agy99           PSEEVPARVASLVERLKAAEKELERARLASVRAAAVNAAAGAERIGNVRL
MLBr_00512|M.leprae_Br4923          PSEEVHARVATLVERLKAAEKELERARQANVQAAATKAAAGAEWIGNVRV
Mb2585c|M.bovis_AF2122/97           PSEEVPARVANLVERLRAAEKELERVRMASARAAATNAAAGAQRIGNVRL
Rv2555c|M.tuberculosis_H37Rv        PSEEVPARVANLVERLRAAEKELERVRMASARAAATNAAAGAQRIGNVRL
MAV_3431|M.avium_104                PSEEVPARVANLVERLRAAEKELERMRLASARAAAGNAAAGAERIGNVRV
TH_0114|M.thermoresistible__bu      PSEEVPDRVANLVEKLRAAEKELERLRLANAKAAVSDAVAQAEQVGRVRL
MAB_2851c|M.abscessus_ATCC_199      PSEEVPGRVATLVERLKVAEKELEQTRLASVKASIATLVDNAERIGSVTV
                                    **:**  ** .***:*:.*****:: * ...:::    .  *: :* : :

Mflv_3763|M.gilvum_PYR-GCK          VAQRMAGGISAGDLRSLVGDIRGKLGSDPAVVALISE---ADDDTVPFVV
Mvan_2640|M.vanbaalenii_PYR-1       VAQRMAGGISGADLRSLVGEIRGKLGSDPAVVALIAE---GDNDSVPFVV
MSMEG_3025|M.smegmatis_MC2_155      VAQRMSGGMSANDLRSLVGDIRGKLGSEPAVVALIAE---GENDAVPFVV
MMAR_2170|M.marinum_M               VAQRMSSEMTPADLRTLVGDIRGKLGSDPAVVALIAAPAGGESSTVPYVV
MUL_1754|M.ulcerans_Agy99           VAQRMSSEMTPADLRTLVGDIRGKLGSDPAVVALIAAPAGGESSTVPYVV
MLBr_00512|M.leprae_Br4923          VVQRMSGPIAPDDLRFLVGDIRGKLGSDPAVVALIAVTSDGPTATVPYAV
Mb2585c|M.bovis_AF2122/97           VAQRMSGGMTAADLRSLIGDIRGKLGSEPAVVALIAE---GESQTVPYAV
Rv2555c|M.tuberculosis_H37Rv        VAQRMSGGMTAADLRSLIGDIRGKLGSEPAVVALIAE---GESQTVPYAV
MAV_3431|M.avium_104                VAQRMSGGMTAADLRSLVGDIRGKLGSDPAVVALIAE---GEGGSVPYAV
TH_0114|M.thermoresistible__bu      VARRIDAGLNAGELRNLVGDIRGKLGSDPAVVALMAAT---DDGSVPFVV
MAB_2851c|M.abscessus_ATCC_199      VAHRLPDGTGAGDLRSLVGDIRGRLGSDPAVVALIAAG----EGSVPFVV
                                    *.:*:       :** *:*:***:***:******::        :**:.*

Mflv_3763|M.gilvum_PYR-GCK          AVNQAAQDRGLRANDLVKVLGAAVNGRGGGKADLAQGSGKGAAGIDAALA
Mvan_2640|M.vanbaalenii_PYR-1       AVNPAAQDRGVRADELVKVMGAAVNGRGGGKADLAQGSGKGAAGIDAALA
MSMEG_3025|M.smegmatis_MC2_155      AVNPAAQDLGLRANDLVKQFAAPVNGRGGGKADLAQGSGKGAAGIDAALA
MMAR_2170|M.marinum_M               AANRAAQGLGLGANELIKHLATAVDGRGGGKADLAQGSGKKPAGIDAALE
MUL_1754|M.ulcerans_Agy99           AANQAAQGLGLGANELIKHLAAAVDGRGGGKADLAQGSGKKPAGIAAALE
MLBr_00512|M.leprae_Br4923          AANPAAQDLGIRANDLVEQLAMVVDGRGGGKADLAQGSGKDPTGIDAALD
Mb2585c|M.bovis_AF2122/97           AANPAAQDLGIRANDLVKQLAVAVEGRGGGKADLAQGSGKNPTGIDAALD
Rv2555c|M.tuberculosis_H37Rv        AANPAAQDLGIRANDLVKQLAVAVEGRGGGKADLAQGSGKNPTGIDAALD
MAV_3431|M.avium_104                AANPAAQDLGIRANDLVKQLAAPVDGRGGGKADLAQGSGKDPAGIDAALD
TH_0114|M.thermoresistible__bu      AVNPAAQDLGLRANNLVKVLAPEVDGRGGGKVDLAQGSGKKAAGIDAALA
MAB_2851c|M.abscessus_ATCC_199      SVNQAAQDAGLRANDLVGAIGPAVDGRGGGKADTAQGSGKDPAGIDAALQ
                                    :.* ***. *: *::*:  :.  *:******.* ****** .:** *** 

Mflv_3763|M.gilvum_PYR-GCK          AIR---AEMGRS-
Mvan_2640|M.vanbaalenii_PYR-1       AIR---AEIGRS-
MSMEG_3025|M.smegmatis_MC2_155      ALR---AEIGRS-
MMAR_2170|M.marinum_M               ALR---AEIARVG
MUL_1754|M.ulcerans_Agy99           ALR---AEIARVG
MLBr_00512|M.leprae_Br4923          TVR---AQIAQVG
Mb2585c|M.bovis_AF2122/97           AVRSEIAVIARVG
Rv2555c|M.tuberculosis_H37Rv        AVRSEIAVIARVG
MAV_3431|M.avium_104                AVRSEIAAIARVG
TH_0114|M.thermoresistible__bu      ALR---AEIARS-
MAB_2851c|M.abscessus_ATCC_199      ALR---AQIRRA-
                                    ::*   * : :