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M. ulcerans Agy99 MUL_1749 (-)

annotation: transglutaminase family protein
coordinates: 1934521 - 1936188
length: 555

MGSASMSIKVALEHRTSYTFDKLVQVYPHVVRLRPAPHSRTPIEAYSLRVEPTEHFVNWQQDALGNFMAR
LVFPKPMQHLTITVGLIADLKVINPFDFFIEEWAETWPAEGLTYPKALADDLKPYLRPVDETGEESGPGD
LVRAWVANFSVPEGTRTIDFLVAINHAVNADVGYSVRMEPGVQTPDFTLRTGIGSCRDSAWLLVSILRQF
GLAARFVSGYLVQLASDIEALDGPSGPTADFTDLHAWTEVYIPGAGWIGLDPTSGLFAGEGHIPLAATPH
PASAAPISGGTGVCNTVLEFSNTVTRVHEDPRVTLPYTDEAWQTICDVGRRVDERLAAGDVRLTMGGEPT
FVSVDNQTDKEWRTAADGPHKRSRASDLAARLKARWAPEGLVQRSQRHCPLRRLIGRAPPDPRDRGRPPP
LRGHLQRLPGAPAGHDNPDIHVGGVRFKAWQPPSALHPTFSADGPLQFELIDLTAGTSRGGCTYHVTHPG
GLAYDEPPVNAVTAESRRARRFEATGFTPGKLDLSDIREKQARMFTDIGAPGILDLRRVRTVQQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1749--100% (555)transglutaminase family protein
M. ulcerans Agy99MUL_1746-5e-1025.80% (283) hypothetical protein MUL_1746
M. ulcerans Agy99MUL_3673-8e-0824.09% (303) putative transglutaminase-like protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2595-0.085.39% (397) hypothetical protein Mb2595
M. gilvum PYR-GCKMflv_3771-0.082.35% (391) transglutaminase domain-containing protein
M. tuberculosis H37RvRv2566-0.085.39% (397) hypothetical protein Rv2566
M. leprae Br4923MLBr_02678-8e-9850.48% (418) hypothetical protein MLBr_02678
M. abscessus ATCC 19977MAB_2859c-1e-17272.89% (391) transglutaminase family protein
M. marinum MMMAR_2165-0.0100.00% (396) transglutaminase family protein
M. avium 104MAV_3439-2e-1227.27% (286) transglutaminase domain-containing protein
M. smegmatis MC2 155MSMEG_3016-0.080.05% (391) hypothetical protein MSMEG_3016
M. thermoresistible (build 8)-----
M. vanbaalenii PYR-1Mvan_2628-0.071.28% (484) transglutaminase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MUL_1749|M.ulcerans_Agy99           ---------------------MMGSASMSIKVALEHRTSYTFDKLVQVYP
MMAR_2165|M.marinum_M               ----------------------MGSASMSIKVALEHRTSYTFDKLVQVYP
Mb2595|M.bovis_AF2122/97            MPLRPTQVSSTGRTRCAGRSGVISSAAMSIKVALEHRTSYTFDRLVRVYP
Rv2566|M.tuberculosis_H37Rv         MPLRPTQVSGTGRTRCAGRSGVISSAAMSIKVALEHRTSYTFDRLVRVYP
Mflv_3771|M.gilvum_PYR-GCK          ---------------------------MGIKVALEHRTSYTFDRLVEVHP
Mvan_2628|M.vanbaalenii_PYR-1       ---------------------------MGIKVALEHRTSYTFDRLVEVYP
MSMEG_3016|M.smegmatis_MC2_155      ---------------------------MGIKVALEHRTSYTFDRLVEIHP
MAB_2859c|M.abscessus_ATCC_199      ---------------------------MGIKVALEHRTSYAFDRLVQVHP
MLBr_02678|M.leprae_Br4923          ---------------------MMRSAAMNIKVTLEHRTSYTFNRLVQVCP
MAV_3439|M.avium_104                ----------------MPEADQQADGGAARRHRVTHRTEYRYSDVVTSSY
                                                                  :  : ***.* :. :*    

MUL_1749|M.ulcerans_Agy99           HVVRLRPAPHSRTPIEAYSLRVEPTEHFVNWQQDALGNFMARLVFPKPMQ
MMAR_2165|M.marinum_M               HVVRLRPAPHSRTPIEAYSLRVEPTEHFVNWQQDALGNFMARLVFPKPMQ
Mb2595|M.bovis_AF2122/97            HIVRLRPAPHSRTSIEAYSLRIEPADHFINWQQDALGNFLARLVFPNPMR
Rv2566|M.tuberculosis_H37Rv         HIVRLRPAPHSRTSIEAYSLRIEPADHFINWQQDALGNFLARLVFPNPMR
Mflv_3771|M.gilvum_PYR-GCK          HVVRLRPAPHSRTPIEAYSLQVEPADHFVNWQQDAFGNFLARLVFTTRAR
Mvan_2628|M.vanbaalenii_PYR-1       HVVRLRPAPHSRTPIEAYSLQVEPADHFINWQQDAFGNFLARLVFPTRTR
MSMEG_3016|M.smegmatis_MC2_155      HVVRLRPAPHCRTPIDAYSLTVEPADHFINWQQDAFGNHMARLVFPNRAR
MAB_2859c|M.abscessus_ATCC_199      HEIRLRPAPHTRTPIEAYSLRIAPDDHFINWQQDAFGNFLARVVFPNRTR
MLBr_02678|M.leprae_Br4923          HVVRVHLAPHSRPPIEAHSLQIEPAGHFINCQQDTLGNGLTRLVLPNPMR
MAV_3439|M.avium_104                GRGFLTPRDSLRQRCVAHRLTIDPAPADSSTSTDCYGNISSYFHVTEPHH
                                        :      *    *: * : *     . . *  **  : . ..   :

MUL_1749|M.ulcerans_Agy99           HLTITVGLIADLKVINPFDFFIEEWAETWPA-----EGLTYPKALADDLK
MMAR_2165|M.marinum_M               HLTITVGLIADLKVINPFDFFIEEWAETWPA-----EGLTYPKALADDLK
Mb2595|M.bovis_AF2122/97            QLRITVGLIADLKVINPFDFFIEDWAEIWPC-----AGMAYPKALADDLR
Rv2566|M.tuberculosis_H37Rv         QLRITVGLIADLKVINPFDFFIEDWAEIWPC-----AGMAYPKALADDLR
Mflv_3771|M.gilvum_PYR-GCK          SLTITVGLIADLKVVNPFDFFIEDYAER--------VGFAYPKALAEDLK
Mvan_2628|M.vanbaalenii_PYR-1       SLTVTVGLIADMKVVNPFDFFIEDYAEQ--------VGFTYPESLAEDLK
MSMEG_3016|M.smegmatis_MC2_155      ELTVTVGLIADLKVINPFDFFIEDYAET--------VPFEYPRALREDLK
MAB_2859c|M.abscessus_ATCC_199      QLSITVGLIADLKSVNPFDFFIEEWAEH--------IGFVYPPALAADLE
MLBr_02678|M.leprae_Br4923          RRSIGFGLITNLKMISPFDCYIENWAETWPATARSGPTFTYPEALAEDLK
MAV_3439|M.avium_104                SLTVTSDSIVDVNPPAPGLYATGPAVQPWEAAR----PAGRRGALATEFT
                                       :  . *.:::   *        .:                :*  :: 

MUL_1749|M.ulcerans_Agy99           PYLRPVDETGEESGPGDLVRAWVANFSVPEGTRTI---DFLVAINHAVNA
MMAR_2165|M.marinum_M               PYLRPVDETGEESGPGDLVRAWVANFSVPEGTRTI---DFLVAINHAVNA
Mb2595|M.bovis_AF2122/97            PYLRPVDEDGDGSGPGELTQAWVRNFTVPDGTRTI---DFLVALNRAINA
Rv2566|M.tuberculosis_H37Rv         PYLRPVDEDGDGSGPGELTQAWVRNFTVPDGTRTI---DFLVALNRAINA
Mflv_3771|M.gilvum_PYR-GCK          PYLRPVDEDGEGTGPGDLAAAWVSNFSVATGTRTI---DFLVALNRAVNA
Mvan_2628|M.vanbaalenii_PYR-1       PYLRPVDEEGPGSGPGDLVEAWVKNFTVASGTRTI---DYLVALNRAVNA
MSMEG_3016|M.smegmatis_MC2_155      PYLRPVDEGAEGSGPGELCAAWVSNFTMPPGTATI---QFLVALNQAVNA
MAB_2859c|M.abscessus_ATCC_199      PYLKPVDESEPGSGPGELVRAWVANFTMAPTTRII---DYLVTLNQALCS
MLBr_02678|M.leprae_Br4923          PYLRPVDEAGNRFVDNELVWAWIRNFPVPDGIRTINFINFLVAFNQAMNA
MAV_3439|M.avium_104                LDLDPPE-----------ITDEVRDYAAPSFAPGRPLIEVLRDLASRIFT
                                      * * :               : ::. .         : *  :   : :

MUL_1749|M.ulcerans_Agy99           DVGYSVRMEPGVQTPDFTLRTGIGSCRDSAWLLVSILRQFGLAARFVSG-
MMAR_2165|M.marinum_M               DVGYSVRMEPGVQTPDFTLRTGIGSCRDSAWLLVSILRQFGLAARFVSG-
Mb2595|M.bovis_AF2122/97            DVGYCVRMEPGVQTPDFTLRTGVGSCRDSAWLLVSILRQFGLAARFVSG-
Rv2566|M.tuberculosis_H37Rv         DVGYCVRMEPGVQTPDFTLRTGVGSCRDSAWLLVSILRQFGLAARFVSG-
Mflv_3771|M.gilvum_PYR-GCK          DVGYSVRMEPGVQTPDVTLRTGIGSCRDSAWLLVSILRQLGLAARFVSG-
Mvan_2628|M.vanbaalenii_PYR-1       DVGYSVRMEPGVQTPDFTLRTGIGSCRDSAWLLVSILRQLGLAARFVSG-
MSMEG_3016|M.smegmatis_MC2_155      DVGYSVRMEAGVQTPDHTLRTGIGSCRDSAWLLVSILRQLGFAARFVSG-
MAB_2859c|M.abscessus_ATCC_199      DVGYAVRLEPGVQSPDTTLAVGIGSCRDTAWLLVSILRQKGLAARFVSG-
MLBr_02678|M.leprae_Br4923          EVSDIVCMEHGVPTTDFTLRTGISSCRDSAWLLVSILWQMRLTAWVVSSS
MAV_3439|M.avium_104                DFTYRSGSTTISTGVAEVLAAREGVCQDFARLAIACLRAHGLAASYVSG-
                                    :.               .* .  . *:* * * :: *    ::*  **. 

MUL_1749|M.ulcerans_Agy99           ----YLVQLASDIEALDGPSGPTADFTDLHAWTEVYIPGAGWIGLDPTSG
MMAR_2165|M.marinum_M               ----YLVQLASDIEALDGPSGPTADFTDLHAWTEVYIPGAGWIGLDPTSG
Mb2595|M.bovis_AF2122/97            ----YLVQLASDIEALDGPSGPAADFTDLHAWSEAYIPGAGWIGLDPTSG
Rv2566|M.tuberculosis_H37Rv         ----YLVQLASDIEALDGPSGPAADFTDLHAWAEAYIPGAGWIGLDPTSG
Mflv_3771|M.gilvum_PYR-GCK          ----YLVQLTSDVEALDGPSGPAADFTDLHAWTEVYIPGAGWIGLDPTSG
Mvan_2628|M.vanbaalenii_PYR-1       ----YLVQLTSDIEALDGPSGPAADFTDLHAWTEVYIPGAGWIGLDPTSG
MSMEG_3016|M.smegmatis_MC2_155      ----YLVQLTSDVEALDGPSGPAADFTDLHAWTEVYIPGAGWIGLDPTSG
MAB_2859c|M.abscessus_ATCC_199      ----YLVQLTSDIAEIDGPSGPVADFTDLHAWAEVYIPGAGWVGLDPTSG
MLBr_02678|M.leprae_Br4923          ATSYNCPPISRHSTSHRGLPPNSPTCTPGPKCPSPVRAKSGWTRSRGCSP
MAV_3439|M.avium_104                ------YLATDPPPGKDRMIGIDATHAWAAVWTPHEPGQFEWLGVDPTND
                                             :             .  :     .        *      . 

MUL_1749|M.ulcerans_Agy99           LFAGEGHIPLAATPHPASAAPISGGTGVCNTVLEFSNTVTRVHEDPRVTL
MMAR_2165|M.marinum_M               LFAGEGHIPLAATPHPASAAPISGGTGVCNTVLEFSNTVTRVHEDPRVTL
Mb2595|M.bovis_AF2122/97            LLAGEGHIPLAATPHPASAAPISGGTDVCDTVLEFSNTVTRVHEDPRVTL
Rv2566|M.tuberculosis_H37Rv         LLAGEGHIPLAATPHPASAAPISGGTDVCDTVLEFSNTVTRVHEDPRVTL
Mflv_3771|M.gilvum_PYR-GCK          LFAGEGHIPLSATPHPESAAPITGATEPCETVLEFSNVVTRVHEDPRVTL
Mvan_2628|M.vanbaalenii_PYR-1       LFAGEGHIPLSATPHPESAAPITGATEPCETTLEFSNVVTRVHEDPRVTL
MSMEG_3016|M.smegmatis_MC2_155      LFAGEGHIPLSATPHPESAAPVTGATGVCEASLEFSNVVTRVHEDPRVTL
MAB_2859c|M.abscessus_ATCC_199      LFAGEGHIPLSATPHPSTSAAITGATDMCESTLDFSNTVTRVHEDPRVTL
MLBr_02678|M.leprae_Br4923          TRSAYRWQPHHILRRQRRPTAQPTRAKRCWTSLTLS---TQVQEDPHITL
MAV_3439|M.avium_104                QMIDERYIVVGRGRDYADVPPLRG--------IIYTNSQHSVIDVSVDVV
                                                       ..           :  :     * : .  .:

MUL_1749|M.ulcerans_Agy99           PYTDEAWQTICDVGRRVDERLAAGDVRLTMGGEPTFVSVDNQTD---KEW
MMAR_2165|M.marinum_M               PYTDEAWQTICDVGRRVDERLAAGDVRLTMGGEPTFVSVDNQTD---KEW
Mb2595|M.bovis_AF2122/97            PYTDESWKTICEVGQRVDERLAAADVRLTVGGEPTFVSVDNQVA---EEW
Rv2566|M.tuberculosis_H37Rv         PYTDESWKTICEVGQRVDERLAAADVRLTVGGEPTFVSVDNQVA---EEW
Mflv_3771|M.gilvum_PYR-GCK          PYTDASWAAINALGRRVDERLREADVRLTMGGEPTFVSIDNQVD---PEW
Mvan_2628|M.vanbaalenii_PYR-1       PYTEESWAAINALGRRVDERLTAGDVRLTVGGEPTFVSIDNQVD---PEW
MSMEG_3016|M.smegmatis_MC2_155      PYTDAAWASIVDLGGRVDRRLADADVRLTMGGEPTFVSIDNQVD---PEW
MAB_2859c|M.abscessus_ATCC_199      PYTASAWEAVVALGEEIDARLDAAGVGLTMGGEPTFVSIDDQTS---EQW
MLBr_02678|M.leprae_Br4923          PYSDVAWHAICAIG-------QHGYQRLTVGGKPTVVLVNIHPNKGRKEW
MAV_3439|M.avium_104                PYA-----------------------------------------------
                                    **:                                               

MUL_1749|M.ulcerans_Agy99           RTAADGPHKRSRASDLAARLKARWAPEGLVQRSQ-RHCP-----------
MMAR_2165|M.marinum_M               RTAADGPHKRSRASDLAARLKARWAPEGLVQRSQGRWYPGEPLPRWQIAL
Mb2595|M.bovis_AF2122/97            RTAADGPHKRERASDLAARLKAVWAPQGLIHRGQGRWYPGEPLPRWQIAL
Rv2566|M.tuberculosis_H37Rv         RTAADGPHKRERASDLAARLKAVWAPQGLIHRGQGRWYPGEPLPRWQIAL
Mflv_3771|M.gilvum_PYR-GCK          TTAADGPHKRERASALTARLKKVWAPQGLVQRSQGKWYPGEPLPRWQIGL
Mvan_2628|M.vanbaalenii_PYR-1       TTDADGPHKRERASALAARLKKVWAPQGLVQRSQGKWYPGEPLPRWQIGL
MSMEG_3016|M.smegmatis_MC2_155      TTDADGPHKRERASALAARLKNVWAPGGLVQRSQGKWYPGEPLPRWQIAL
MAB_2859c|M.abscessus_ATCC_199      TTAADGEHKRARASDLAARLKAAWAPTGLVQRSQGKWYPGEPLPRWQIGL
MLBr_02678|M.leprae_Br4923          TMVAKSPSKRQPASDLTARLKAAWAPQGLIHFRQGQWYTGEPLPQWQITL
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           LRRLIGR--------------------APPDPRD----------------
MMAR_2165|M.marinum_M               YRRTDGRPLWTDPTLLADPW-L-----DPPTPVDSDAAHQVLSAFAEGMG
Mb2595|M.bovis_AF2122/97            YWRTDGRPLWTNDALLADPWGA-----PPADPVDDDAAYRVLAGIADGLG
Rv2566|M.tuberculosis_H37Rv         YWRTDGRPLWTNDALLADPWGA-----PPADPVDDDAAYRVLAGIADGLG
Mflv_3771|M.gilvum_PYR-GCK          YWRADGEPLWSDDRLLADPWPET----PGVRGIAPDAHRALLAAIADGLG
Mvan_2628|M.vanbaalenii_PYR-1       FWRTDGEPLWADESLLADPWQET----SDTRTPTPDAGHRLLAVIADGLG
MSMEG_3016|M.smegmatis_MC2_155      YWRTDGLPLWTDAELLADPWSG------KTREVAPDAAERLLSEIAAGLG
MAB_2859c|M.abscessus_ATCC_199      YWRRDGQPLWSDPELLADPWDGE-----RQWSTPQGADRALLSALASDLG
MLBr_02678|M.leprae_Br4923          YWRTKGQPLWTNDALLTDTWKAGPSERNKTTLEDSELAHKVLAQAADGLG
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2165|M.marinum_M               LPLSQVRPAYEDPLARLAATVRLPSGDPVDPIDDLDPETDSDTPVGRAEL
Mb2595|M.bovis_AF2122/97            LPISQVRPAYEDPLSRLAAAVRMPAGDPVESGDDLGCDTNPDTPTGRAAL
Rv2566|M.tuberculosis_H37Rv         LPISQVRPAYEDPLSRLAAAVRMPAGDPVESGDDLGCDTNPDTPTGRAAL
Mflv_3771|M.gilvum_PYR-GCK          LPADRVRPAYEDPLTRLIAAVRRPEGPPVAADDDLA----ADDAAGRAAL
Mvan_2628|M.vanbaalenii_PYR-1       LPAGHVRPAYEDPLARLVGAVRQPAGPPVDADDDLA----VDSADGRAQL
MSMEG_3016|M.smegmatis_MC2_155      LPGTQVRPAFEDPLSRLAAAVRLPAGDPVGADEDLA----EDGADARAEL
MAB_2859c|M.abscessus_ATCC_199      LPDSQVRPAYEDPLSRLVASIRRPAGDPIDTADDPAP--YEDSAERRTGL
MLBr_02678|M.leprae_Br4923          LPLTQMRAAYKDTLRRLAAKVRIPSGAPVQLSDDRGP-TTPDSAVNRVAL
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           -----------------------------------RGR------------
MMAR_2165|M.marinum_M               LARLDASVTSAAAHVLPLHRREDGSGWASADWRLRRGRLVLIEGDSPAGL
Mb2595|M.bovis_AF2122/97            LAPR----------------------------------------------
Rv2566|M.tuberculosis_H37Rv         LARLDEAITSPAAYVLPLHRRDDGQGWASANWRLRRGRIVLLEGDSPAGL
Mflv_3771|M.gilvum_PYR-GCK          MQRLDESVGEPTAFVLPLHRRDDDAGWASADWTLRRGRIVLLDGDSPAGL
Mvan_2628|M.vanbaalenii_PYR-1       LARLEESVTEPSAFVLPVHRRDDDSGWAGAQWTLRRGRVVLLEGDSPAGL
MSMEG_3016|M.smegmatis_MC2_155      LARLESPVDAPAAHVLPLHRADDGTGWASADWRLRRGRIVLLDGDSPAGL
MAB_2859c|M.abscessus_ATCC_199      LDRLDEAVTQPTAYVLPLHRGED--GWESADWTLRRGRIVLTDGDSPAGL
MLBr_02678|M.leprae_Br4923          LTRLEESVTLPDAYMLSLHSRDDNLSWVQATLQLHRGCIVLIEDASLAGL
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2165|M.marinum_M               RLPLNSISWQPPRTSFDVDPVTVGYAL-----PEPATAEAVDAVLDDSEN
Mb2595|M.bovis_AF2122/97            --------------------------------------------------
Rv2566|M.tuberculosis_H37Rv         RLPLDSISWRPPRASFDADPVAVRSTL-----PAELHTDR--AVVEDPET
Mflv_3771|M.gilvum_PYR-GCK          RLPLNSISWKPPKPTFEADPIHRRPALGRGAALARSATATPEETSDDDEW
Mvan_2628|M.vanbaalenii_PYR-1       RLPLHSISWQPPRPTFDADPIERRPPLPRAGSVTAAASPDMATTVEDADW
MSMEG_3016|M.smegmatis_MC2_155      RLPLNSISWQPPRPSFEADPLAVD-------TDTEPAPGRRTATVVDADG
MAB_2859c|M.abscessus_ATCC_199      RLPLDAVSWQPAPQSAEADPLSAP-------AELGAQRSPAPAVVVPAEG
MLBr_02678|M.leprae_Br4923          LLPLDSISWPRPHVSFYLDPMTFWR-------AWSAEPNTAAAVLENPDS
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2165|M.marinum_M               APPTAIVAEVRDGLLYIFIPPTEALEDFVDLVTRIEAAAAKANCPLVLEG
Mb2595|M.bovis_AF2122/97            --------------------------------------------------
Rv2566|M.tuberculosis_H37Rv         APTTALVAEVRGGLVHIFLPPTDALEHFIDLVARVEAAATTANCPVVIEG
Mflv_3771|M.gilvum_PYR-GCK          VPTTALVGEIRDGLLYVFLPPVDELEHFIDLIARIESAAASIDCPVVIEG
Mvan_2628|M.vanbaalenii_PYR-1       VPTTALVGEIRDGLLYVFLPPTEELEHFVDLVERIEAAAAAIDCPVVIEG
MSMEG_3016|M.smegmatis_MC2_155      APTTALVAEIRDGLLYVFLPPTAELDDFLDLVARVEAAAAAVGVPVVVEG
MAB_2859c|M.abscessus_ATCC_199      APVTALVAEIRDGLLYLFLPPLEQVDDFVDLIARVEAAVT---CPLVIEG
MLBr_02678|M.leprae_Br4923          APPTAMVAEIRGEFLSIFLSPTETLKHFVSLVSGGETAAANIGCPVVIEG
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           --PPP---------------------------------------------
MMAR_2165|M.marinum_M               YGPPPDPRLESTTITPDPGVIEVNVAPTASFEEQRQQLETLYEEARLARL
Mb2595|M.bovis_AF2122/97            --------------------------------------------------
Rv2566|M.tuberculosis_H37Rv         YGPPPDPRLTSTTITPDPGVIEVNIAPTASFAEQRQQLETLYQQARLARL
Mflv_3771|M.gilvum_PYR-GCK          YGPPPDPRLTTMSITPDPGVIEVNVAPTESFVEQRAQLETLYREARLARL
Mvan_2628|M.vanbaalenii_PYR-1       YGPPNDARLSSVTITPDPGVIEVNVAPTASFAEQRAQLETLYAEARLARL
MSMEG_3016|M.smegmatis_MC2_155      YGPPTDPRITSTTITPDPGVIEVNVAPTASFGEQNKQLETLYEQARLARL
MAB_2859c|M.abscessus_ATCC_199      YGPPPDPRIEAMSITPDPGVIEVNVTPTASFAEQSRQLQVLYEEARKARL
MLBr_02678|M.leprae_Br4923          YGLPTDLRLKSMCVKPG------QVAAAASFAAERQQLETFYAQAGMARL
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2165|M.marinum_M               STESFDVDGSHGGTGGGNHITLGGVTPADSPLLRRPDLLVSLLTYWQRHP
Mb2595|M.bovis_AF2122/97            --------------------------------------------------
Rv2566|M.tuberculosis_H37Rv         TTEAFDVDGTHGGTGGGNHITLGGVTPADSPLLRRPDLLVSLLTYWQRHP
Mflv_3771|M.gilvum_PYR-GCK          STEAFDVDGTHGGTGGGNHITLGGVTPADSPLLRRPDLLVSMLTYWQRHP
Mvan_2628|M.vanbaalenii_PYR-1       STESFDVDGSHGGTGGGNHITLGGITPADSPLLRRPDLLVSLLTYWQRHP
MSMEG_3016|M.smegmatis_MC2_155      STESFDVDGTHSGTGGGNHITLGGITPADSPLLRRPDLLVSLLTYWQRHP
MAB_2859c|M.abscessus_ATCC_199      TTESFDVDGTHTGTGGGNHITLGGRTPATSPLLRRPDLLVSLLTYWQHHP
MLBr_02678|M.leprae_Br4923          STESFDDSGAHGRTGGNNHITLGDVTP----LRRHPDLLVSLLTCWQRHP
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2165|M.marinum_M               SLSYVFAGRFVGTTSQAPRVDEGRAEALYELEIAFAEIA---RLSAGGAA
Mb2595|M.bovis_AF2122/97            --------------------------------------------------
Rv2566|M.tuberculosis_H37Rv         SLSYLFAGRFVGTTSQAPRVDEGRAEALYELEIAFAEILRLSPSSGGGRP
Mflv_3771|M.gilvum_PYR-GCK          ALSYLFAGRFIGTTSQSPRVDEGRPDALYELEIAFAEIARLSKAEGGAAP
Mvan_2628|M.vanbaalenii_PYR-1       SLSYLFAGRFIGTTSQAPRVDEGRPESLYELEIAFAEIARLAQAPGGAK-
MSMEG_3016|M.smegmatis_MC2_155      ALSYLFAGRFIGTTSQAPRVDEGRAEALYELEIAFAEIARLTATDAPQP-
MAB_2859c|M.abscessus_ATCC_199      ALSYLFSGRFVGTTSQAPRVDEGREEALYELEIAFAEIERLADSEAPWH-
MLBr_02678|M.leprae_Br4923          SRSYRFAGQFVGPISQAPQVDEVR--------------------------
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           ---------------------------LRGHLQRLPG-------------
MMAR_2165|M.marinum_M               K-------------------PWVTDRALRHLLTDITGNTHRAEFCIDKLY
Mb2595|M.bovis_AF2122/97            --------------------------------------------------
Rv2566|M.tuberculosis_H37Rv         Q-------------------PWVTDRALRHLLTDITGNTHRAEFCIDKLY
Mflv_3771|M.gilvum_PYR-GCK          EHGRSASSAPEHGRSASSAPPWLVDRALRHLLTDITGNTHRAEFCIDKLY
Mvan_2628|M.vanbaalenii_PYR-1       --------------------AWVTDRALRHLLTDITGNTHRAEFCIDKLY
MSMEG_3016|M.smegmatis_MC2_155      ---------------------WVLDRALRHLLTDITGNTHRAEFCIDKLY
MAB_2859c|M.abscessus_ATCC_199      -----------------------IDRSLRHLLTDITGNTHRAEFCIDKLY
MLBr_02678|M.leprae_Br4923          --------------------------AFRHLVVDITGNIHHAEFCIDKLH
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           APAG----------------------------------------------
MMAR_2165|M.marinum_M               SPEGTRGRLGLLELRGFEMPPHLRMAMVQSLLVRSLVAWFWEQPLRAPLI
Mb2595|M.bovis_AF2122/97            --------------------------------------------------
Rv2566|M.tuberculosis_H37Rv         SPDSARGRLGLLELRGFEMPPHLHMAMVQSLLVRSLVAWFWDQPLRAPLI
Mflv_3771|M.gilvum_PYR-GCK          SPDSARGRLGLLELRGFEMPPHPQMAMVQSLLVRSLVAWFWDEPLRAPLI
Mvan_2628|M.vanbaalenii_PYR-1       SPDSARGRLGLLELRGFEMPPHHQMAMVQSLLVRALVAWFWEEPLRAPLI
MSMEG_3016|M.smegmatis_MC2_155      SPDGARGRLGLLELRGFEMPPHHQMAMVQALLVRSLVAWFWDEPLRAPLI
MAB_2859c|M.abscessus_ATCC_199      SPDSARGRLGLLELRGFEMPPHFQMAMVQSLLVRALVARFWAQPLSAPLV
MLBr_02678|M.leprae_Br4923          SHDNTHGRLSLLELRGFAMPLYLQMVIVRWLLVRSLVAWFWEEPLRASVI
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2165|M.marinum_M               RHGANLHGRYLLPHFLIHDIADVAADLRANGIDFETSWLDPFTEFRFPRI
Mb2595|M.bovis_AF2122/97            --------------------------------------------------
Rv2566|M.tuberculosis_H37Rv         RHGANLHGRYLLPHFLIHDIADVAADLRAHGIAFETSWLDPFTEFRFPRI
Mflv_3771|M.gilvum_PYR-GCK          RHGANLHGRYLLPHFLIHDIAEVAADLRAHGVEFDTSWLDPFTEFRFPRI
Mvan_2628|M.vanbaalenii_PYR-1       RHGANLHGRYLLPHFLIHDIAEVAADLRAHGVEFDTSWLDPFTEFRFPRI
MSMEG_3016|M.smegmatis_MC2_155      RHGANLHGRYLLPHFLIRDIADVAADLRAHGIDFLTSWLDPFTEFRFPRI
MAB_2859c|M.abscessus_ATCC_199      RHGANLHGRYLLPHFIIHDIAQVAADLRAHDIAFETSWLDPFTEFRFPRI
MLBr_02678|M.leprae_Br4923          RHGTNLHGRYLFPHFVSHDMAAIATSLREHGLAFETNWLYPFIEFRLPRL
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2165|M.marinum_M               GTAVFDGVEIELRGAIEPWNTLGEESTASGTARYVDSSVERLQIRVIGAD
Mb2595|M.bovis_AF2122/97            --------------------------------------------------
Rv2566|M.tuberculosis_H37Rv         GTAVFDGIEIELRGAIEPWHTLGEEATAAGTARYVDSSVERIQVRIIGAD
Mflv_3771|M.gilvum_PYR-GCK          GTAVLGGVEIELRGAIEPWNVLGEESTAGGTARYVDSSVERLQVRLIGAD
Mvan_2628|M.vanbaalenii_PYR-1       GTAVLGGVELELRDAIEPWNVLGEEATAGGTARYVDSSVERLQVRLIGAD
MSMEG_3016|M.smegmatis_MC2_155      GTAVFDGVELELRGAIEPWNVLGEESTAGGTARYVDSSVERIQVRLVGAD
MAB_2859c|M.abscessus_ATCC_199      GTAVFDGIEIELRGAIEPWRVLGEEATSGGTARYVDSSIERVQVRVIGAD
MLBr_02678|M.leprae_Br4923          GTSVFHGVEIELRNAIEPWTTFGEK-------------------------
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           -----------------HDNPDIHVGGVRFKAWQPPSALHPTFSADGPLQ
MMAR_2165|M.marinum_M               RHRYVVTCNGYPVPLLATDNPDIHVGGVRFKAWQPPSALHPTISADGPLQ
Mb2595|M.bovis_AF2122/97            --------------------------------------------------
Rv2566|M.tuberculosis_H37Rv         RHRYVVTCNGYPMPLLATDNPDIHVGGVRFKAWQPPSALHPTITVDGPLR
Mflv_3771|M.gilvum_PYR-GCK          RSRYLVTVNGHPVPMLATDNPDVQVGGVRYRAWQPPSALHPTITVDGPLR
Mvan_2628|M.vanbaalenii_PYR-1       RQRHVVVVNGFPVPLLATDNPDVQVGGVRYRAWQPPSALHPTITVDGPLR
MSMEG_3016|M.smegmatis_MC2_155      RDRYVVTANGHPIPLLATEKSDVQVGGVRYRAWQPPSALHPSITVDGPLR
MAB_2859c|M.abscessus_ATCC_199      RSRYVVTCNGEPIPLLSTENPDVQVAGVRYRAWQPPSALHPSITVDDPLR
MLBr_02678|M.leprae_Br4923          --------------------------------------------------
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           FELIDLTAGTSRGGCTYHVTHPGGLAYDEPPVNAVTAESRRARRFEATGF
MMAR_2165|M.marinum_M               FELIDLTAGTSRGGCTYHVTHPGGLAYDEPPVNAVTAESRRARRFEATGF
Mb2595|M.bovis_AF2122/97            --------------------------------------------------
Rv2566|M.tuberculosis_H37Rv         FELIDIATATSCGGCTYHVAHPGGRAYDEPPVNAVEAEARRARRFEATGF
Mflv_3771|M.gilvum_PYR-GCK          FELIDAATGVSRGGCTYHVSHPGGRSYDSPPVNAVEAESRRARRFEATGF
Mvan_2628|M.vanbaalenii_PYR-1       FELVDAAAGVSRGGCTYHVSHPGGRSYDRPPVNAVEAESRRGRRFEATGF
MSMEG_3016|M.smegmatis_MC2_155      FELIDTATGTSKGGCTYHIVHPGGRSYDTSPVNAVEAESRRGRRFEVIGF
MAB_2859c|M.abscessus_ATCC_199      FELIDTANALSRGGCTYHVSHPGGRSYDDPPVNAVAAEARRGRRFDATGY
MLBr_02678|M.leprae_Br4923          ------STVTSRGGCTYHASHTGSKAINTG--STLEAQARWSRRFEATGF
MAV_3439|M.avium_104                --------------------------------------------------
                                                                                      

MUL_1749|M.ulcerans_Agy99           TPGKLDLSDIREKQARMFTDIGAPGILDLRRVRTVQQ--
MMAR_2165|M.marinum_M               TPGKLDLSDIREKQARMFTDIGAPGILDLRRVRTVQQ--
Mb2595|M.bovis_AF2122/97            ---------------------------------------
Rv2566|M.tuberculosis_H37Rv         TPGKLDLSDIREKQARISTDIGAPGILDLRRVRTVQQ--
Mflv_3771|M.gilvum_PYR-GCK          TPGAVDLAALREKLARQSTDVGAPGILDLRRVRTVLQ--
Mvan_2628|M.vanbaalenii_PYR-1       TPGRVDLADLREKQARQSTDVGAPGILDLRRVRTVLQ--
MSMEG_3016|M.smegmatis_MC2_155      TPGKVDMSVIRERQARQSTDVGAPGILDLRRVRTVLR--
MAB_2859c|M.abscessus_ATCC_199      TTGRVDLSDLREKQARMSTDAVAPGILDLRRARTVGRR-
MLBr_02678|M.leprae_Br4923          IPSKITMSCIRKSKS-----VSPPTSTRLASSTSDASAP
MAV_3439|M.avium_104                ---------------------------------------